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The map label for this gene is blh [H]

Identifier: 110635694

GI number: 110635694

Start: 3636170

End: 3637120

Strand: Reverse

Name: blh [H]

Synonym: Meso_3366

Alternate gene names: 110635694

Gene position: 3637120-3636170 (Counterclockwise)

Preceding gene: 110635696

Following gene: 110635693

Centisome position: 82.43

GC content: 59.41

Gene sequence:

>951_bases
ATGAAGACACACCGGCTTCCTTCGGCTAAAGCACGAGCGCGTATTGGACAGGTTCGTCAGGAGGTGGCGATGGGATCCCC
AAAGGCGCCGCAGGTAACGGCGTTTTACGACAAGCGCACCTTTTCGCTGCAATATGTCGCCGCCGACCCGGAAACGGGAA
GATGTGCGATCATCGATCCGGTCCTCGATTATGACGAGAAGTCCGGCGCCACGGCGACGGATGGTGCCGATGCCATCCTT
GATTTCATCGCCAGTCAGCGCCTTACCGTCCAGTGGATACTCGACACTCATCCGCACGCGGACCACCTCTCGGCGGCTGC
CTATCTCAAGGAGAAGACCGGCGCGCCCACCGCCATCGGCGAACATGTGATCGACATGCAGAGGCTCTGGAAGGATATTT
ATAACCTGCCGGATTTTCCCGCCGACGGTTCCCAATGGGACAAGCTTTTTGCCGAAGGCGAAAACTTCCTCGTGGGTGAA
ATCGAAGCACGCGTGCTTTTTTCCCCAGGCCATACGCTGGCGTCGATCACCTATTTGATCGGGGATGCGGCCTTCGTGCA
TGATACGCTCTTCATGCCGGACGGAGGGACGGCCCGGGCGGATTTTCCCGGCGGCAGCGCGGCAAGGCTCTGGCGCTCCA
TCGAAGAAATCCTGTCGCTGCCGGATGAGACAAGGGTTTTTACCGGGCACGACTATCAGCCAGGCGGCCGGGAGCTGCGT
TGGGAAAGCACCGTCGCCGAGCAAAAGGCCGAAAATATCCACATCGCGAAATGCCGCACCGAGGAAGAGTTCGTGAGGCT
GCGTGAGGCCCGCGACAGAACCTTGCCCATGCCGAACCTCATCCTTCACGCGTTGCAGGTGAACATCAATGGCGGAAGGC
TACCGGAGCCGGAATCAAATGGCCGGCGCTATCTGAAGATTCCTCTGAATGCGCTTGGCCGGTTCCGCTGA

Upstream 100 bases:

>100_bases
TGCCTTAGAGAAACGGCGAGGTCAAGGCCGTTCGATACCTGTTCCCCATTCCTGGAGGCTAAGGCATACTGCCTTGGAAC
GCGGGACTCATCCGGCTGGC

Downstream 100 bases:

>100_bases
ACGGGAGGATTTACCGCCGCATTTTCGACAAGCCGATTGGCCATAGGCGTTCATCATTTTGTTGTTAGACGGTCATATTT
TTATGCAATTTAGCTTCCTG

Product: beta-lactamase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKTHRLPSAKARARIGQVRQEVAMGSPKAPQVTAFYDKRTFSLQYVAADPETGRCAIIDPVLDYDEKSGATATDGADAIL
DFIASQRLTVQWILDTHPHADHLSAAAYLKEKTGAPTAIGEHVIDMQRLWKDIYNLPDFPADGSQWDKLFAEGENFLVGE
IEARVLFSPGHTLASITYLIGDAAFVHDTLFMPDGGTARADFPGGSAARLWRSIEEILSLPDETRVFTGHDYQPGGRELR
WESTVAEQKAENIHIAKCRTEEEFVRLREARDRTLPMPNLILHALQVNINGGRLPEPESNGRRYLKIPLNALGRFR

Sequences:

>Translated_316_residues
MKTHRLPSAKARARIGQVRQEVAMGSPKAPQVTAFYDKRTFSLQYVAADPETGRCAIIDPVLDYDEKSGATATDGADAIL
DFIASQRLTVQWILDTHPHADHLSAAAYLKEKTGAPTAIGEHVIDMQRLWKDIYNLPDFPADGSQWDKLFAEGENFLVGE
IEARVLFSPGHTLASITYLIGDAAFVHDTLFMPDGGTARADFPGGSAARLWRSIEEILSLPDETRVFTGHDYQPGGRELR
WESTVAEQKAENIHIAKCRTEEEFVRLREARDRTLPMPNLILHALQVNINGGRLPEPESNGRRYLKIPLNALGRFR
>Mature_316_residues
MKTHRLPSAKARARIGQVRQEVAMGSPKAPQVTAFYDKRTFSLQYVAADPETGRCAIIDPVLDYDEKSGATATDGADAIL
DFIASQRLTVQWILDTHPHADHLSAAAYLKEKTGAPTAIGEHVIDMQRLWKDIYNLPDFPADGSQWDKLFAEGENFLVGE
IEARVLFSPGHTLASITYLIGDAAFVHDTLFMPDGGTARADFPGGSAARLWRSIEEILSLPDETRVFTGHDYQPGGRELR
WESTVAEQKAENIHIAKCRTEEEFVRLREARDRTLPMPNLILHALQVNINGGRLPEPESNGRRYLKIPLNALGRFR

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=288, Percent_Identity=27.4305555555556, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1787158, Length=166, Percent_Identity=28.9156626506024, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17538952, Length=269, Percent_Identity=26.7657992565056, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221330176, Length=300, Percent_Identity=27, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 35215; Mature: 35215

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTHRLPSAKARARIGQVRQEVAMGSPKAPQVTAFYDKRTFSLQYVAADPETGRCAIIDP
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEEEEEECCCCCCCEEEECH
VLDYDEKSGATATDGADAILDFIASQRLTVQWILDTHPHADHLSAAAYLKEKTGAPTAIG
HHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHH
EHVIDMQRLWKDIYNLPDFPADGSQWDKLFAEGENFLVGEIEARVLFSPGHTLASITYLI
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEEEEEEEEECCCCHHHHHHHHH
GDAAFVHDTLFMPDGGTARADFPGGSAARLWRSIEEILSLPDETRVFTGHDYQPGGRELR
HCHHHHHHEEECCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEE
WESTVAEQKAENIHIAKCRTEEEFVRLREARDRTLPMPNLILHALQVNINGGRLPEPESN
EHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHEEEHEEEECCCCCCCCCCC
GRRYLKIPLNALGRFR
CCEEEEEEHHHCCCCC
>Mature Secondary Structure
MKTHRLPSAKARARIGQVRQEVAMGSPKAPQVTAFYDKRTFSLQYVAADPETGRCAIIDP
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEEEEEECCCCCCCEEEECH
VLDYDEKSGATATDGADAILDFIASQRLTVQWILDTHPHADHLSAAAYLKEKTGAPTAIG
HHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHH
EHVIDMQRLWKDIYNLPDFPADGSQWDKLFAEGENFLVGEIEARVLFSPGHTLASITYLI
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEEEEEEEEECCCCHHHHHHHHH
GDAAFVHDTLFMPDGGTARADFPGGSAARLWRSIEEILSLPDETRVFTGHDYQPGGRELR
HCHHHHHHEEECCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEE
WESTVAEQKAENIHIAKCRTEEEFVRLREARDRTLPMPNLILHALQVNINGGRLPEPESN
EHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHEEEHEEEECCCCCCCCCCC
GRRYLKIPLNALGRFR
CCEEEEEEHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]