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The map label for this gene is ffh [H]

Identifier: 110635669

GI number: 110635669

Start: 3612340

End: 3613908

Strand: Reverse

Name: ffh [H]

Synonym: Meso_3341

Alternate gene names: 110635669

Gene position: 3613908-3612340 (Counterclockwise)

Preceding gene: 110635670

Following gene: 110635668

Centisome position: 81.9

GC content: 64.31

Gene sequence:

>1569_bases
ATGTTCGAGACTCTCCAGGAACGCCTTGGCGCAATCCTGAACAATCTCACCGGGCGCGGAGCGCTTTCGGAGGCGGATGT
TTCCGCCGCCCTGCGCGAGGTGCGCCGGGCGTTGATCGAGGCCGACGTGGCGCTCGATGTCGTACGTTCCTTCACGGACC
GGGTGCGCGAAAAGGCCGTTGGCGCCCAGGTGCTCAAATCCGTGAAGCCGGGCCAGATGGTCGTCAAGATCGTTCATGAC
GAACTGGTCGAGATGCTGGGCAGCGAGGGCGAGAGCGTTGACCTCAATGCCCCGGCGCCGGTCGTCGTGATGATGGTGGG
CTTGCAGGGTTCCGGCAAAACCACGACGTCGGGCAAGATCGCCAAGCGAATGTCGGAGCGCCAGGGCAAGAAGGTGCTGA
TGGCATCGCTCGACACGCGTAGGCCCGCCGCGCAGGAGCAGCTTCGCCAGCTCGGAGAGCAGACGGGCATTGCCACGCTG
CCCATAGTGGCGGGGCAGACTCCTGTCGATATCGCGCGGCGCGCCGTGCAGGCGGCCAAGCTCGGCGGCCATGACGTGGT
GATCCTCGATACGGCCGGCCGTACGCATATCGACGAGCCACTGATGGCCGAGATGAGCGATATCAGGCGGGCGTCCAACC
CGCATGAGATCCTGCTCGTGGCCGACTCGCTGACCGGTCAGGATGCGGTGAACCTCGCGAAGAATTTTGACGAGCGCGTC
GGCATTACCGGCCTTGTGCTTACCCGGATGGACGGCGACGGGCGCGGCGGCGCGGCGCTTTCCATGCGTGCGGTCACCGG
CAAGCCGATCAAGCTGATCGGCACCGGCGAGAAAATGGACGCGCTGGAGGAATTCCATCCCCGGCGCATCGCCGACCGCA
TTCTCGGCATGGGCGATATCGTTTCGCTCGTGGAGAAAGCTGCCGAAACCATTGACGCGAAGAAGGCCGCGGCGATGGCG
AAGAAGATGCAGGAGGGCAAGTTCGACTTGAACGACCTCGCCGATCAGCTTCGCCAGATGCAGAAGATGGGCGGCATGGG
CGGCATCATGGGCATGATGCCTGGCATGGGAAAGATGAAGGATCAGCTTGCTGCCGCCGGCCTTGACGACAAGATGTTTG
GCCGCCAGATCGCCATCATCCAGTCGATGACGCCCAAGGAGCGCGCCAATCCGGATCTCCTGAAGCACAGCCGCAAACAG
CGCATCGCCGCAGGCTCCGGTACCGATGCCGCGCAGATCAATAAGCTGCTCAAGATGCACCGCCAGATGGCCGACATGAT
GAAGGCGATGGGCGGCAAGGGCAAGAAAGGCGGCATGATGCGCGGCCTCATGGGAGGGATGGCGCAGAAAATGGGTCTCG
GCGGTATGCCGGGGGGCATGGGAGGCATGCCGGACCTTTCCAAGATGGACCCGAAGCAGCTTGAAGCATTGCAGAGACAG
CTAGGCGGCGCCGGTGGCCTGCCGCCTGGCCTTCCCAAGGGGCTCTCCGGCCTGCCGGGGGGCGGAGGCCTTCCGGGTTT
GCCTGGGCTTCCCGGTGCTGGCCTGCCCGGCCTGCCGAAGAAGAAATGA

Upstream 100 bases:

>100_bases
CGCAATGCGCCCCCGGGTGCTTTTCGGTTTTGCGAGGTTTAACCCTCGCCGCGGATGCATTACCTCTCGTGTCTGACAAC
ACGGGACAAGAGGAACGCGG

Downstream 100 bases:

>100_bases
GGGGGAGAAGCCAATGAGCATGGATGTGGATCCCGCCAGGGAACGCCTGTTGGAACTGCGCGCCTCGATCGACAATCTCG
ACGCCGCGCTGATCCACGTT

Product: signal recognition particle subunit FFH/SRP54 (srp54)

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MFETLQERLGAILNNLTGRGALSEADVSAALREVRRALIEADVALDVVRSFTDRVREKAVGAQVLKSVKPGQMVVKIVHD
ELVEMLGSEGESVDLNAPAPVVVMMVGLQGSGKTTTSGKIAKRMSERQGKKVLMASLDTRRPAAQEQLRQLGEQTGIATL
PIVAGQTPVDIARRAVQAAKLGGHDVVILDTAGRTHIDEPLMAEMSDIRRASNPHEILLVADSLTGQDAVNLAKNFDERV
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGTGEKMDALEEFHPRRIADRILGMGDIVSLVEKAAETIDAKKAAAMA
KKMQEGKFDLNDLADQLRQMQKMGGMGGIMGMMPGMGKMKDQLAAAGLDDKMFGRQIAIIQSMTPKERANPDLLKHSRKQ
RIAAGSGTDAAQINKLLKMHRQMADMMKAMGGKGKKGGMMRGLMGGMAQKMGLGGMPGGMGGMPDLSKMDPKQLEALQRQ
LGGAGGLPPGLPKGLSGLPGGGGLPGLPGLPGAGLPGLPKKK

Sequences:

>Translated_522_residues
MFETLQERLGAILNNLTGRGALSEADVSAALREVRRALIEADVALDVVRSFTDRVREKAVGAQVLKSVKPGQMVVKIVHD
ELVEMLGSEGESVDLNAPAPVVVMMVGLQGSGKTTTSGKIAKRMSERQGKKVLMASLDTRRPAAQEQLRQLGEQTGIATL
PIVAGQTPVDIARRAVQAAKLGGHDVVILDTAGRTHIDEPLMAEMSDIRRASNPHEILLVADSLTGQDAVNLAKNFDERV
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGTGEKMDALEEFHPRRIADRILGMGDIVSLVEKAAETIDAKKAAAMA
KKMQEGKFDLNDLADQLRQMQKMGGMGGIMGMMPGMGKMKDQLAAAGLDDKMFGRQIAIIQSMTPKERANPDLLKHSRKQ
RIAAGSGTDAAQINKLLKMHRQMADMMKAMGGKGKKGGMMRGLMGGMAQKMGLGGMPGGMGGMPDLSKMDPKQLEALQRQ
LGGAGGLPPGLPKGLSGLPGGGGLPGLPGLPGAGLPGLPKKK
>Mature_522_residues
MFETLQERLGAILNNLTGRGALSEADVSAALREVRRALIEADVALDVVRSFTDRVREKAVGAQVLKSVKPGQMVVKIVHD
ELVEMLGSEGESVDLNAPAPVVVMMVGLQGSGKTTTSGKIAKRMSERQGKKVLMASLDTRRPAAQEQLRQLGEQTGIATL
PIVAGQTPVDIARRAVQAAKLGGHDVVILDTAGRTHIDEPLMAEMSDIRRASNPHEILLVADSLTGQDAVNLAKNFDERV
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGTGEKMDALEEFHPRRIADRILGMGDIVSLVEKAAETIDAKKAAAMA
KKMQEGKFDLNDLADQLRQMQKMGGMGGIMGMMPGMGKMKDQLAAAGLDDKMFGRQIAIIQSMTPKERANPDLLKHSRKQ
RIAAGSGTDAAQINKLLKMHRQMADMMKAMGGKGKKGGMMRGLMGGMAQKMGLGGMPGGMGGMPDLSKMDPKQLEALQRQ
LGGAGGLPPGLPKGLSGLPGGGGLPGLPGLPGAGLPGLPKKK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=513, Percent_Identity=30.9941520467836, Blast_Score=218, Evalue=7e-57,
Organism=Homo sapiens, GI226371618, Length=449, Percent_Identity=32.0712694877506, Blast_Score=195, Evalue=8e-50,
Organism=Homo sapiens, GI23308697, Length=311, Percent_Identity=29.5819935691318, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI295424842, Length=311, Percent_Identity=29.5819935691318, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI89061728, Length=159, Percent_Identity=35.8490566037736, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1788963, Length=429, Percent_Identity=53.1468531468531, Blast_Score=442, Evalue=1e-125,
Organism=Escherichia coli, GI1789874, Length=268, Percent_Identity=37.3134328358209, Blast_Score=154, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17539958, Length=494, Percent_Identity=30.3643724696356, Blast_Score=214, Evalue=6e-56,
Organism=Caenorhabditis elegans, GI193206261, Length=293, Percent_Identity=30.7167235494881, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6325345, Length=500, Percent_Identity=32.2, Blast_Score=231, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6320498, Length=317, Percent_Identity=26.1829652996845, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI17647949, Length=495, Percent_Identity=31.3131313131313, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24641198, Length=320, Percent_Identity=28.75, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 54992; Mature: 54992

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.5 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.5 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFETLQERLGAILNNLTGRGALSEADVSAALREVRRALIEADVALDVVRSFTDRVREKAV
CHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAQVLKSVKPGQMVVKIVHDELVEMLGSEGESVDLNAPAPVVVMMVGLQGSGKTTTSGKI
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCCCCCCCHHHH
AKRMSERQGKKVLMASLDTRRPAAQEQLRQLGEQTGIATLPIVAGQTPVDIARRAVQAAK
HHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEECEECCCCCHHHHHHHHHHHH
LGGHDVVILDTAGRTHIDEPLMAEMSDIRRASNPHEILLVADSLTGQDAVNLAKNFDERV
CCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGTGEKMDALEEFHPRRIADRILGMGDI
CCEEEEEEEECCCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHCHHHH
VSLVEKAAETIDAKKAAAMAKKMQEGKFDLNDLADQLRQMQKMGGMGGIMGMMPGMGKMK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHH
DQLAAAGLDDKMFGRQIAIIQSMTPKERANPDLLKHSRKQRIAAGSGTDAAQINKLLKMH
HHHHHCCCCHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RQMADMMKAMGGKGKKGGMMRGLMGGMAQKMGLGGMPGGMGGMPDLSKMDPKQLEALQRQ
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LGGAGGLPPGLPKGLSGLPGGGGLPGLPGLPGAGLPGLPKKK
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFETLQERLGAILNNLTGRGALSEADVSAALREVRRALIEADVALDVVRSFTDRVREKAV
CHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAQVLKSVKPGQMVVKIVHDELVEMLGSEGESVDLNAPAPVVVMMVGLQGSGKTTTSGKI
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCCCCCCCHHHH
AKRMSERQGKKVLMASLDTRRPAAQEQLRQLGEQTGIATLPIVAGQTPVDIARRAVQAAK
HHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEECEECCCCCHHHHHHHHHHHH
LGGHDVVILDTAGRTHIDEPLMAEMSDIRRASNPHEILLVADSLTGQDAVNLAKNFDERV
CCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GITGLVLTRMDGDGRGGAALSMRAVTGKPIKLIGTGEKMDALEEFHPRRIADRILGMGDI
CCEEEEEEEECCCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHCHHHH
VSLVEKAAETIDAKKAAAMAKKMQEGKFDLNDLADQLRQMQKMGGMGGIMGMMPGMGKMK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHH
DQLAAAGLDDKMFGRQIAIIQSMTPKERANPDLLKHSRKQRIAAGSGTDAAQINKLLKMH
HHHHHCCCCHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RQMADMMKAMGGKGKKGGMMRGLMGGMAQKMGLGGMPGGMGGMPDLSKMDPKQLEALQRQ
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LGGAGGLPPGLPKGLSGLPGGGGLPGLPGLPGAGLPGLPKKK
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA