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The map label for this gene is ruvB

Identifier: 110635505

GI number: 110635505

Start: 3448562

End: 3449599

Strand: Reverse

Name: ruvB

Synonym: Meso_3176

Alternate gene names: 110635505

Gene position: 3449599-3448562 (Counterclockwise)

Preceding gene: 110635506

Following gene: 110635504

Centisome position: 78.18

GC content: 63.58

Gene sequence:

>1038_bases
ATGAGCGAGCCGGACCGCATCGTTTCTGCTGTCCAGCGCGGCGAGGATATCGACACGACGATGCGTCCGCAGTCGCTGGA
CGAATTTGTCGGCCAGAAGACGGCACGCGCCAATCTCAAAGTGTTTATTGAGGCGGCGCGCTCGCGGGGCGAAGCGCTGG
ATCACGTGCTGTTCGTCGGCCCACCGGGCCTCGGCAAGACCACGCTTGCCCAGATCATGGCGCGAGAGCTCGGCGTCAAT
TTCCGGTCCACCTCCGGCCCGGTTATCGCCAAGGCAGGTGACCTTGCGGCGCTTCTCACCAATCTTGAGGAGCGCGACGT
GCTCTTCATCGACGAGATCCACCGGCTCAATCCTGCCGTGGAAGAAATCCTCTATCCCGCGATGGAGGACTACCAGCTCG
ATCTCATCATAGGCGAGGGCCCCGCGGCGCGCTCGGTCAAGATCGACCTTGCCAAATTCACGCTCGTTGCCGCGACCACC
CGCCTTGGGCTCTTGACCACGCCGCTGCGTGACCGGTTCGGCATCCCGATCAGGCTCGAATTCTACACGGTCGACGAATT
GCAGGCGATCGTCACGCGAGGCGCACGCATTATGGGCATGCCGCTTGCCGAAGACGGCGCGGAGGAGATCGCACGCCGCG
CCCGAGGAACGCCCCGAATCGCCGGCCGCCTTCTGCGCCGGGTGCGCGATTTCGCCTATGTGGCGGGCGCGGAAAACGTG
ACGCGGCAGATCGCCGACGCGGCGCTTTCAAGGCTTGAGGTGGATGCGCTCGGCCTTGATCAGCTTGACCGGCGCTATCT
CCATATGATCGTGGAGAATTTCGGTGGCGGCCCTGTGGGGATCGAGACAATCGCGGCTGCGCTTTCCGAGCCGCGCGACG
CCATCGAAGACATTATCGAGCCCTATCTCATCCAGCAGGGCTTCATTCAGCGCACACCGCGCGGCCGGGTGCTTGCGGCC
AAGGCCTGGAGGCATCTCGGGCTGAACCCGCCGAAGGAGCTTGCGCAGTCGCAGATCAATTTATTCGAGGAGGAGTGA

Upstream 100 bases:

>100_bases
TCGAGTTCGTGAAGGAAATCGGGAGACCCTGGGCGCGCCGGAGGAGGCCGCGGCTGACGTGCCGCGCCGCCTCCCGCATT
CCCGGCATGGAGCTTTTGTC

Downstream 100 bases:

>100_bases
ATTTCGCGAAAGGGAGCAGCGAGTAGAGATCTGGTAAGGCGATCAGACCAGCAGATCTTTCCATTCACTGCTCCCTGTTC
GCTATTCGCTTGTACGCTAT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MSEPDRIVSAVQRGEDIDTTMRPQSLDEFVGQKTARANLKVFIEAARSRGEALDHVLFVGPPGLGKTTLAQIMARELGVN
FRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLNPAVEEILYPAMEDYQLDLIIGEGPAARSVKIDLAKFTLVAATT
RLGLLTTPLRDRFGIPIRLEFYTVDELQAIVTRGARIMGMPLAEDGAEEIARRARGTPRIAGRLLRRVRDFAYVAGAENV
TRQIADAALSRLEVDALGLDQLDRRYLHMIVENFGGGPVGIETIAAALSEPRDAIEDIIEPYLIQQGFIQRTPRGRVLAA
KAWRHLGLNPPKELAQSQINLFEEE

Sequences:

>Translated_345_residues
MSEPDRIVSAVQRGEDIDTTMRPQSLDEFVGQKTARANLKVFIEAARSRGEALDHVLFVGPPGLGKTTLAQIMARELGVN
FRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLNPAVEEILYPAMEDYQLDLIIGEGPAARSVKIDLAKFTLVAATT
RLGLLTTPLRDRFGIPIRLEFYTVDELQAIVTRGARIMGMPLAEDGAEEIARRARGTPRIAGRLLRRVRDFAYVAGAENV
TRQIADAALSRLEVDALGLDQLDRRYLHMIVENFGGGPVGIETIAAALSEPRDAIEDIIEPYLIQQGFIQRTPRGRVLAA
KAWRHLGLNPPKELAQSQINLFEEE
>Mature_344_residues
SEPDRIVSAVQRGEDIDTTMRPQSLDEFVGQKTARANLKVFIEAARSRGEALDHVLFVGPPGLGKTTLAQIMARELGVNF
RSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLNPAVEEILYPAMEDYQLDLIIGEGPAARSVKIDLAKFTLVAATTR
LGLLTTPLRDRFGIPIRLEFYTVDELQAIVTRGARIMGMPLAEDGAEEIARRARGTPRIAGRLLRRVRDFAYVAGAENVT
RQIADAALSRLEVDALGLDQLDRRYLHMIVENFGGGPVGIETIAAALSEPRDAIEDIIEPYLIQQGFIQRTPRGRVLAAK
AWRHLGLNPPKELAQSQINLFEEE

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=334, Percent_Identity=62.874251497006, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI1787119, Length=124, Percent_Identity=34.6774193548387, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_MESSB (Q11DH7)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_675713.1
- ProteinModelPortal:   Q11DH7
- SMR:   Q11DH7
- STRING:   Q11DH7
- GeneID:   4182266
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_3176
- NMPDR:   fig|266779.1.peg.109
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- PhylomeDB:   Q11DH7
- ProtClustDB:   PRK00080
- BioCyc:   MSP266779:MESO_3176-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 38049; Mature: 37918

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPDRIVSAVQRGEDIDTTMRPQSLDEFVGQKTARANLKVFIEAARSRGEALDHVLFVG
CCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHCEEEEEC
PPGLGKTTLAQIMARELGVNFRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLNPAV
CCCCCHHHHHHHHHHHHCCCEECCCCCEEECCCHHHHHHHCCCCCCEEHHHHHHHCCHHH
EEILYPAMEDYQLDLIIGEGPAARSVKIDLAKFTLVAATTRLGLLTTPLRDRFGIPIRLE
HHHHHHCCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEE
FYTVDELQAIVTRGARIMGMPLAEDGAEEIARRARGTPRIAGRLLRRVRDFAYVAGAENV
EEEHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHH
TRQIADAALSRLEVDALGLDQLDRRYLHMIVENFGGGPVGIETIAAALSEPRDAIEDIIE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHH
PYLIQQGFIQRTPRGRVLAAKAWRHLGLNPPKELAQSQINLFEEE
HHHHHHHHHHCCCCCCEEHHHHHHHCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEPDRIVSAVQRGEDIDTTMRPQSLDEFVGQKTARANLKVFIEAARSRGEALDHVLFVG
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHCEEEEEC
PPGLGKTTLAQIMARELGVNFRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLNPAV
CCCCCHHHHHHHHHHHHCCCEECCCCCEEECCCHHHHHHHCCCCCCEEHHHHHHHCCHHH
EEILYPAMEDYQLDLIIGEGPAARSVKIDLAKFTLVAATTRLGLLTTPLRDRFGIPIRLE
HHHHHHCCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEE
FYTVDELQAIVTRGARIMGMPLAEDGAEEIARRARGTPRIAGRLLRRVRDFAYVAGAENV
EEEHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHH
TRQIADAALSRLEVDALGLDQLDRRYLHMIVENFGGGPVGIETIAAALSEPRDAIEDIIE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHH
PYLIQQGFIQRTPRGRVLAAKAWRHLGLNPPKELAQSQINLFEEE
HHHHHHHHHHCCCCCCEEHHHHHHHCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA