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The map label for this gene is tolQ [H]

Identifier: 110635503

GI number: 110635503

Start: 3447031

End: 3447762

Strand: Reverse

Name: tolQ [H]

Synonym: Meso_3174

Alternate gene names: 110635503

Gene position: 3447762-3447031 (Counterclockwise)

Preceding gene: 110635504

Following gene: 110635502

Centisome position: 78.14

GC content: 60.93

Gene sequence:

>732_bases
ATGGAAAGTATTGAGCTCGCCGCGCCTGGTGGGGATCTCTCCATCTGGGCACTGTTTTGGCAGGCCGGATGGGTGGTCAA
GCTCGTAATGATCGGCCTGCTTGGCGCCTCTATTTGGAGTTGGGCCATCATCATCGACAAGTGGTTGAGCTTCGCGCGGA
TGCGGGTGGCACTCAACCGTTTCGAGCAGGTCTTCTGGTCGGGCCAATCGCTCGAAGAACTTTATCGTTCACTGTCCGAT
CGCAAGACCAGCGGCATGGGCTCGATTTTCGTTGCCGCGATGCGCGAATGGAAAAAGAGCTTCGAGAAAGGCGCGCGTTC
GCCCCTCGGGCTCCAGACCCGTATCGACAAGGCGATGGATCTGGCGCTCACCCGCGAAATGGAACGGCTGGAGAGCAAGC
TGGGGTTCCTTGCTTCGGTCGGCGCCTCGGCTCCCTTCATCGGCCTGTTCGGCACTGTGGTGGGCATCATGACGTCTTTC
CAGGCGATCGCTGGCTCGAAATCGACCAATCTCGCTGTCGTGGCCCCCGGTATCGCCGAGGCGCTTCTCGCCACGGCCAT
CGGCCTTCTCGCGGCCATCCCGGCTGTCATCGCATACAACAAGCTCACGGCGGATGCCGGCAACATCGCCTCGCGGATGG
AAGGCTTCGCGGACGAGTTCTCGGCCATACTCTCGCGACAAATCGATGAGAAAGTCGCCCCCAAAGCCCGGGCGGTGGAG
GAGTATGCCTGA

Upstream 100 bases:

>100_bases
AGAGCCTTTCGGGGGGCGTTGCGGCAACGGTGCGAAGACACGCATTCGCAACGGGATGGACCCGCATCGAAGCTGCCCGA
TTTTTAGAGGACGGTAGGGT

Downstream 100 bases:

>100_bases
TGGGGATGTCGGTCGCTTCGGCTAGGGGCGCAAATGGGCGCCGGCGCAAAGGCCGCCGTCATGCGCCTATGTCCGAGATC
AATGTCACGCCTTTCGTGGA

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MESIELAAPGGDLSIWALFWQAGWVVKLVMIGLLGASIWSWAIIIDKWLSFARMRVALNRFEQVFWSGQSLEELYRSLSD
RKTSGMGSIFVAAMREWKKSFEKGARSPLGLQTRIDKAMDLALTREMERLESKLGFLASVGASAPFIGLFGTVVGIMTSF
QAIAGSKSTNLAVVAPGIAEALLATAIGLLAAIPAVIAYNKLTADAGNIASRMEGFADEFSAILSRQIDEKVAPKARAVE
EYA

Sequences:

>Translated_243_residues
MESIELAAPGGDLSIWALFWQAGWVVKLVMIGLLGASIWSWAIIIDKWLSFARMRVALNRFEQVFWSGQSLEELYRSLSD
RKTSGMGSIFVAAMREWKKSFEKGARSPLGLQTRIDKAMDLALTREMERLESKLGFLASVGASAPFIGLFGTVVGIMTSF
QAIAGSKSTNLAVVAPGIAEALLATAIGLLAAIPAVIAYNKLTADAGNIASRMEGFADEFSAILSRQIDEKVAPKARAVE
EYA
>Mature_243_residues
MESIELAAPGGDLSIWALFWQAGWVVKLVMIGLLGASIWSWAIIIDKWLSFARMRVALNRFEQVFWSGQSLEELYRSLSD
RKTSGMGSIFVAAMREWKKSFEKGARSPLGLQTRIDKAMDLALTREMERLESKLGFLASVGASAPFIGLFGTVVGIMTSF
QAIAGSKSTNLAVVAPGIAEALLATAIGLLAAIPAVIAYNKLTADAGNIASRMEGFADEFSAILSRQIDEKVAPKARAVE
EYA

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=218, Percent_Identity=42.6605504587156, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI1789381, Length=233, Percent_Identity=39.9141630901288, Blast_Score=145, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 26283; Mature: 26283

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESIELAAPGGDLSIWALFWQAGWVVKLVMIGLLGASIWSWAIIIDKWLSFARMRVALNR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEQVFWSGQSLEELYRSLSDRKTSGMGSIFVAAMREWKKSFEKGARSPLGLQTRIDKAMD
HHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LALTREMERLESKLGFLASVGASAPFIGLFGTVVGIMTSFQAIAGSKSTNLAVVAPGIAE
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHH
ALLATAIGLLAAIPAVIAYNKLTADAGNIASRMEGFADEFSAILSRQIDEKVAPKARAVE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
EYA
HCC
>Mature Secondary Structure
MESIELAAPGGDLSIWALFWQAGWVVKLVMIGLLGASIWSWAIIIDKWLSFARMRVALNR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEQVFWSGQSLEELYRSLSDRKTSGMGSIFVAAMREWKKSFEKGARSPLGLQTRIDKAMD
HHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LALTREMERLESKLGFLASVGASAPFIGLFGTVVGIMTSFQAIAGSKSTNLAVVAPGIAE
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHH
ALLATAIGLLAAIPAVIAYNKLTADAGNIASRMEGFADEFSAILSRQIDEKVAPKARAVE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
EYA
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]