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The map label for this gene is stc [H]

Identifier: 110635284

GI number: 110635284

Start: 3214921

End: 3216600

Strand: Reverse

Name: stc [H]

Synonym: Meso_2955

Alternate gene names: 110635284

Gene position: 3216600-3214921 (Counterclockwise)

Preceding gene: 110635297

Following gene: 110635283

Centisome position: 72.9

GC content: 58.81

Gene sequence:

>1680_bases
ATGGCGCCATCACGGCCAATGCGCTGTCCAGCGGAGGAAAAAGCAATGACGCACAGCGATGGCGAGCACGTGCATGGAAT
CGCGGTAATCGATCCGACGGGAGCGGTGCAGTTTCACGCAGGCGCCGCCTCAGACATGCGAGTGCGCGCCATGATCAGCG
ACCCCGCCTGGCTCGCTGAAGCGGCGGAGCGGCGGCTTAGCGCTCTCACTTTAAACGATCAGAGCATGGCGGTGCTGGCC
GTCCCGTTTGTTGGCGGGCATTTCATCGCATTGTTCGAGGAACGTGGAGCGACCGCGATCAAATTTTTGCTGAACGTGGA
TTTCGCGTTCGACATTATAGAGCAGTTGCTTAGCGACCCCTATGATGGAATGGCCATAATCAATGCCGATGAACGGCTCG
TCTACGTCTCGCCCGTTCATGAGAAATTCTTCGGCCTGGAGCCGGGCGGCGGCATCGGTCGTAAAGTACGCGACGTGATC
GAGAATACGCGGCTGCATATCGTGGTGCGCACCGGCATTGCCGAGATCGGTCAGATCCAGAAGATGAATGGAAGCGAGCG
CGTGGTTTCCCGCCTGCCGGTCCGACGAGGGGGAAAGATTGTCGGCGCGATAGGCCGCGTGATGTTCAAGGGCCCGCAAC
AGGTGGAAGCGCTAGCGCGCCGGATCAGTGCGCTGGAACAGGAAATCGCCACGTATAAGTCCGAGCAGCGCAAGCACACA
GAGGCCGAGAAATACCTCTCGTGCATCATCGGGCAGAGCGAGGCTATGGTTCGCCTGCGAGACCAGATTCGCAAGATTGC
GCCGCTGGACATCCCCGTTCTGGTGCAAGGCGAGAGCGGAACGGGCAAGGAATTGGTTGCCCGAGCGCTCCACATGATGA
GCCCACGTCGCGATGCTCGGCTCGTCAATGTCAACGCTGCCGCGCTGCCGGCGCAACTGGTTGAGAGCGAGCTTTTTGGC
TACGAGGGAGGCGCGTTCACAGGCGCCGACAGGAAAGGCCGTGCAGGTAAGTTCGAACTGGCCGACAAGGGTACGATCTT
TCTCGATGAAATCGGCGATATGCCGCTTGAAACGCAATCTAAGCTGCTGCGCATTCTGCAAGACCGTGTTGTCGAGCGGG
TCGGCGGCGCCACCCCCAAGAAGATAGATTTTCGCTTATGTTCGGCGACAAACCGCGACCTTGCGGATTTTGTCGAAACG
GGCCGTTTCCGGCTCGATTTGTTCTACCGGATAAGCCCCATAATTATCCAGATTCCGCCACTGGCGGATAGGCTGGAAGA
CATCCCCCTGCTGCTCGCACATTTTTTGAAGGAACTGTCGGCGCAGCATGGCCGGGATGTTCCCGAGGTAGACAGCAATG
TCTCCGATTATCTCATGGAACGAAGCTGGCCGGGCAATGTGCGTGAACTCTTTCATAACATCGAGCGCGCGCTTGTGTTC
TGCGACAATGGAAAATTGCGAATAGAGAATTTCCAGGAGGCTGAGCGGATGGGGCGCGCTGCGCCGCGCGAGGCGAGCGT
CGTTAGAACGGACACACCTGGCTCCCTGCGTGACACGCTGGATCGCGTCGAACAGGAACTTGTCGTGGCGGCGCTCGACC
GGTTCCACGGCAACAAGAAGAAGGCCGCCGAGTATCTGGGGATCTCGCGCAGCTATCTCTACAAGAAGCTTTCGGGCTGA

Upstream 100 bases:

>100_bases
GACACGGTCGATACTCCAAAATGCAATGTTCGTGCCAGTTTCCGTATGTGTACACTTTATCGGGAAACCGGGTTGACTGT
GTGTGCGCTGAGGACACAAG

Downstream 100 bases:

>100_bases
ACAAATCTGCCGGGGTTTGGCACGGTGATTGCGAAGTCTTCCGTTGAAACGGGAGACTGATAATGGAAGCTACAGTAGCA
GGCGCGAGCCGTGATGGGGT

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 558

Protein sequence:

>559_residues
MAPSRPMRCPAEEKAMTHSDGEHVHGIAVIDPTGAVQFHAGAASDMRVRAMISDPAWLAEAAERRLSALTLNDQSMAVLA
VPFVGGHFIALFEERGATAIKFLLNVDFAFDIIEQLLSDPYDGMAIINADERLVYVSPVHEKFFGLEPGGGIGRKVRDVI
ENTRLHIVVRTGIAEIGQIQKMNGSERVVSRLPVRRGGKIVGAIGRVMFKGPQQVEALARRISALEQEIATYKSEQRKHT
EAEKYLSCIIGQSEAMVRLRDQIRKIAPLDIPVLVQGESGTGKELVARALHMMSPRRDARLVNVNAAALPAQLVESELFG
YEGGAFTGADRKGRAGKFELADKGTIFLDEIGDMPLETQSKLLRILQDRVVERVGGATPKKIDFRLCSATNRDLADFVET
GRFRLDLFYRISPIIIQIPPLADRLEDIPLLLAHFLKELSAQHGRDVPEVDSNVSDYLMERSWPGNVRELFHNIERALVF
CDNGKLRIENFQEAERMGRAAPREASVVRTDTPGSLRDTLDRVEQELVVAALDRFHGNKKKAAEYLGISRSYLYKKLSG

Sequences:

>Translated_559_residues
MAPSRPMRCPAEEKAMTHSDGEHVHGIAVIDPTGAVQFHAGAASDMRVRAMISDPAWLAEAAERRLSALTLNDQSMAVLA
VPFVGGHFIALFEERGATAIKFLLNVDFAFDIIEQLLSDPYDGMAIINADERLVYVSPVHEKFFGLEPGGGIGRKVRDVI
ENTRLHIVVRTGIAEIGQIQKMNGSERVVSRLPVRRGGKIVGAIGRVMFKGPQQVEALARRISALEQEIATYKSEQRKHT
EAEKYLSCIIGQSEAMVRLRDQIRKIAPLDIPVLVQGESGTGKELVARALHMMSPRRDARLVNVNAAALPAQLVESELFG
YEGGAFTGADRKGRAGKFELADKGTIFLDEIGDMPLETQSKLLRILQDRVVERVGGATPKKIDFRLCSATNRDLADFVET
GRFRLDLFYRISPIIIQIPPLADRLEDIPLLLAHFLKELSAQHGRDVPEVDSNVSDYLMERSWPGNVRELFHNIERALVF
CDNGKLRIENFQEAERMGRAAPREASVVRTDTPGSLRDTLDRVEQELVVAALDRFHGNKKKAAEYLGISRSYLYKKLSG
>Mature_558_residues
APSRPMRCPAEEKAMTHSDGEHVHGIAVIDPTGAVQFHAGAASDMRVRAMISDPAWLAEAAERRLSALTLNDQSMAVLAV
PFVGGHFIALFEERGATAIKFLLNVDFAFDIIEQLLSDPYDGMAIINADERLVYVSPVHEKFFGLEPGGGIGRKVRDVIE
NTRLHIVVRTGIAEIGQIQKMNGSERVVSRLPVRRGGKIVGAIGRVMFKGPQQVEALARRISALEQEIATYKSEQRKHTE
AEKYLSCIIGQSEAMVRLRDQIRKIAPLDIPVLVQGESGTGKELVARALHMMSPRRDARLVNVNAAALPAQLVESELFGY
EGGAFTGADRKGRAGKFELADKGTIFLDEIGDMPLETQSKLLRILQDRVVERVGGATPKKIDFRLCSATNRDLADFVETG
RFRLDLFYRISPIIIQIPPLADRLEDIPLLLAHFLKELSAQHGRDVPEVDSNVSDYLMERSWPGNVRELFHNIERALVFC
DNGKLRIENFQEAERMGRAAPREASVVRTDTPGSLRDTLDRVEQELVVAALDRFHGNKKKAAEYLGISRSYLYKKLSG

Specific function: Required For Induction Of Expression Of The Hydrogenase- 4 Structural Genes. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082117, Length=403, Percent_Identity=39.9503722084367, Blast_Score=254, Evalue=7e-69,
Organism=Escherichia coli, GI1788550, Length=346, Percent_Identity=43.9306358381503, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI1790437, Length=315, Percent_Identity=45.3968253968254, Blast_Score=245, Evalue=6e-66,
Organism=Escherichia coli, GI1789233, Length=323, Percent_Identity=40.8668730650155, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1789087, Length=327, Percent_Identity=41.8960244648318, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1790299, Length=353, Percent_Identity=38.2436260623229, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI1788905, Length=327, Percent_Identity=39.4495412844037, Blast_Score=216, Evalue=4e-57,
Organism=Escherichia coli, GI1786524, Length=396, Percent_Identity=36.8686868686869, Blast_Score=215, Evalue=8e-57,
Organism=Escherichia coli, GI87082152, Length=312, Percent_Identity=40.7051282051282, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI87081872, Length=316, Percent_Identity=37.3417721518987, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1787583, Length=312, Percent_Identity=34.6153846153846, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI87081858, Length=300, Percent_Identity=32.6666666666667, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1789828, Length=289, Percent_Identity=30.7958477508651, Blast_Score=115, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 62048; Mature: 61917

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPSRPMRCPAEEKAMTHSDGEHVHGIAVIDPTGAVQFHAGAASDMRVRAMISDPAWLAE
CCCCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCCEEEECCCCCCCEEEEEECCCHHHHH
AAERRLSALTLNDQSMAVLAVPFVGGHFIALFEERGATAIKFLLNVDFAFDIIEQLLSDP
HHHHHHHEEEECCCCEEEEEEECCCCEEEEEEECCCCCEEHHHHHCCHHHHHHHHHHCCC
YDGMAIINADERLVYVSPVHEKFFGLEPGGGIGRKVRDVIENTRLHIVVRTGIAEIGQIQ
CCCEEEEECCCCEEEEECHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEEECCHHHHHHHH
KMNGSERVVSRLPVRRGGKIVGAIGRVMFKGPQQVEALARRISALEQEIATYKSEQRKHT
HCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAEKYLSCIIGQSEAMVRLRDQIRKIAPLDIPVLVQGESGTGKELVARALHMMSPRRDAR
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCE
LVNVNAAALPAQLVESELFGYEGGAFTGADRKGRAGKFELADKGTIFLDEIGDMPLETQS
EEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCCCCHHHH
KLLRILQDRVVERVGGATPKKIDFRLCSATNRDLADFVETGRFRLDLFYRISPIIIQIPP
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHCCCEEEEEEEEECCEEEECCC
LADRLEDIPLLLAHFLKELSAQHGRDVPEVDSNVSDYLMERSWPGNVRELFHNIERALVF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHEEEE
CDNGKLRIENFQEAERMGRAAPREASVVRTDTPGSLRDTLDRVEQELVVAALDRFHGNKK
ECCCCEEECCHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
KAAEYLGISRSYLYKKLSG
HHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure 
APSRPMRCPAEEKAMTHSDGEHVHGIAVIDPTGAVQFHAGAASDMRVRAMISDPAWLAE
CCCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCCEEEECCCCCCCEEEEEECCCHHHHH
AAERRLSALTLNDQSMAVLAVPFVGGHFIALFEERGATAIKFLLNVDFAFDIIEQLLSDP
HHHHHHHEEEECCCCEEEEEEECCCCEEEEEEECCCCCEEHHHHHCCHHHHHHHHHHCCC
YDGMAIINADERLVYVSPVHEKFFGLEPGGGIGRKVRDVIENTRLHIVVRTGIAEIGQIQ
CCCEEEEECCCCEEEEECHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEEECCHHHHHHHH
KMNGSERVVSRLPVRRGGKIVGAIGRVMFKGPQQVEALARRISALEQEIATYKSEQRKHT
HCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAEKYLSCIIGQSEAMVRLRDQIRKIAPLDIPVLVQGESGTGKELVARALHMMSPRRDAR
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCE
LVNVNAAALPAQLVESELFGYEGGAFTGADRKGRAGKFELADKGTIFLDEIGDMPLETQS
EEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCCCCHHHH
KLLRILQDRVVERVGGATPKKIDFRLCSATNRDLADFVETGRFRLDLFYRISPIIIQIPP
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHCCCEEEEEEEEECCEEEECCC
LADRLEDIPLLLAHFLKELSAQHGRDVPEVDSNVSDYLMERSWPGNVRELFHNIERALVF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHEEEE
CDNGKLRIENFQEAERMGRAAPREASVVRTDTPGSLRDTLDRVEQELVVAALDRFHGNKK
ECCCCEEECCHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
KAAEYLGISRSYLYKKLSG
HHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA