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The map label for this gene is mmgC [H]

Identifier: 110635278

GI number: 110635278

Start: 3208552

End: 3209718

Strand: Reverse

Name: mmgC [H]

Synonym: Meso_2949

Alternate gene names: 110635278

Gene position: 3209718-3208552 (Counterclockwise)

Preceding gene: 110635279

Following gene: 110635277

Centisome position: 72.74

GC content: 57.84

Gene sequence:

>1167_bases
ATGCAACTACTCGAGCAGATAAACGCCGCCCGCAAATGGAACGACGACGAACGCGCCGTCATCGACCAGGTCGAGCGCAT
GGTAGAGAAGGTGATCCGCCCGAACGCCGCTGCCTACGACGAGAGCGGCGATTTTCCCTGGGCAAACGTGGAGGCAATCA
ACGAGCTCGGATTGAATACGATTTTCCTGCCCGAGGCTTATGGCGGGATGCCGATGTCTTACGCTCTCTACCTTGAGATC
GTCTCCATAATTTCCGAGGCCTGTGCGTCGACAGGCATCATTTATGCTACCAATTTCCACGGGATGAAGCCGCTGGTCGA
GTTCGGCGATGATGCGCAGCGCGAACGTCTGCTCCCGCGGATCGCCGCGGGGGGATTGGGCGCGCTGGCGATTACCGAGC
CAAGCGCCGGTTCGGACGCCACCTCCATGAAGACCAGCTTTTCTCCCGACGGCGACGAGATCGTTGTCAACGGTTCGAAG
ATCTTCATCTCGAATGGCGACGTCGCCGATCTCTACCTCCTGTTTGGTAAGTGGAGCCAGATCGAGGACCCAAAGAAAGC
CATTTCCGCGCTTATCCTTGAGAAGGGCGCCGAGGGCTTTGAGGTGGTTTCGAAGGAGCGGAAGATGGGGCACAACGCTT
CGTCCACCTGCACGCTCTCCTTCGACAATGTTCGTGTTCCGAGGGCCAATCTTCTCAAAGAGCCAGGCGATGGCCTGTCC
ATCCTGCTGGCCTCGCTCAACCATTCTCGACCGTCGGTCGCGGCACATGCGCGCGGCATCGCCCGCGCCGCTTTTCGAGA
CATGGTCTCTTATGGGAACGATAGAGTGCAAAGCGGGCGCAAGATACTGGATTTCCAGGGAAATCAATTTACGCTTGCTG
ATCTTGCATGCGAACTTGCCATGCTGGAAACCTGGATAGACCACGTCGCCTCGCTTGTGGATTCGAAGGTTTCCGACATC
GGCTTGGCCGCATCTGTTGCCAAGTTGCGCGCGTCCGATCTCGCAATGAAGATGGCCATCGAATGCGTGCAGATGCACGG
CGGATACGGCTATTGCCGCGATTACCGCGCCGAGCGGCTGATGCGCGATGCCAAGATCACCCAGATCTGGGAAGGCACGA
ACCAGATTCACCGCCAACTCATCGGACGGAGCTTCAGAACAAAATGA

Upstream 100 bases:

>100_bases
GGACGTTGCCCGGCTCGTCGCGGCATTGTTCAACGAGGAGATCGGGTTTCTCACGGGTGAAACTATCTATGTCGATGGCG
CGCAAGGGATAAACCATTAG

Downstream 100 bases:

>100_bases
CCGAGATCAAGAAGGTTGCCATCTGCGGCGCAGGCGGAACCATGGGGGCGGGTATAGCGATGGTGGCTGCCCGAGCCGGT
TTTCAGACAATCTGTTTCGA

Product: acyl-CoA dehydrogenase-like

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MQLLEQINAARKWNDDERAVIDQVERMVEKVIRPNAAAYDESGDFPWANVEAINELGLNTIFLPEAYGGMPMSYALYLEI
VSIISEACASTGIIYATNFHGMKPLVEFGDDAQRERLLPRIAAGGLGALAITEPSAGSDATSMKTSFSPDGDEIVVNGSK
IFISNGDVADLYLLFGKWSQIEDPKKAISALILEKGAEGFEVVSKERKMGHNASSTCTLSFDNVRVPRANLLKEPGDGLS
ILLASLNHSRPSVAAHARGIARAAFRDMVSYGNDRVQSGRKILDFQGNQFTLADLACELAMLETWIDHVASLVDSKVSDI
GLAASVAKLRASDLAMKMAIECVQMHGGYGYCRDYRAERLMRDAKITQIWEGTNQIHRQLIGRSFRTK

Sequences:

>Translated_388_residues
MQLLEQINAARKWNDDERAVIDQVERMVEKVIRPNAAAYDESGDFPWANVEAINELGLNTIFLPEAYGGMPMSYALYLEI
VSIISEACASTGIIYATNFHGMKPLVEFGDDAQRERLLPRIAAGGLGALAITEPSAGSDATSMKTSFSPDGDEIVVNGSK
IFISNGDVADLYLLFGKWSQIEDPKKAISALILEKGAEGFEVVSKERKMGHNASSTCTLSFDNVRVPRANLLKEPGDGLS
ILLASLNHSRPSVAAHARGIARAAFRDMVSYGNDRVQSGRKILDFQGNQFTLADLACELAMLETWIDHVASLVDSKVSDI
GLAASVAKLRASDLAMKMAIECVQMHGGYGYCRDYRAERLMRDAKITQIWEGTNQIHRQLIGRSFRTK
>Mature_388_residues
MQLLEQINAARKWNDDERAVIDQVERMVEKVIRPNAAAYDESGDFPWANVEAINELGLNTIFLPEAYGGMPMSYALYLEI
VSIISEACASTGIIYATNFHGMKPLVEFGDDAQRERLLPRIAAGGLGALAITEPSAGSDATSMKTSFSPDGDEIVVNGSK
IFISNGDVADLYLLFGKWSQIEDPKKAISALILEKGAEGFEVVSKERKMGHNASSTCTLSFDNVRVPRANLLKEPGDGLS
ILLASLNHSRPSVAAHARGIARAAFRDMVSYGNDRVQSGRKILDFQGNQFTLADLACELAMLETWIDHVASLVDSKVSDI
GLAASVAKLRASDLAMKMAIECVQMHGGYGYCRDYRAERLMRDAKITQIWEGTNQIHRQLIGRSFRTK

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557231, Length=377, Percent_Identity=32.6259946949602, Blast_Score=205, Evalue=8e-53,
Organism=Homo sapiens, GI187960098, Length=377, Percent_Identity=32.6259946949602, Blast_Score=204, Evalue=8e-53,
Organism=Homo sapiens, GI4557233, Length=392, Percent_Identity=34.9489795918367, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI76496475, Length=374, Percent_Identity=33.9572192513369, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI4557235, Length=374, Percent_Identity=33.9572192513369, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI4501859, Length=377, Percent_Identity=30.2387267904509, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI226958412, Length=391, Percent_Identity=30.9462915601023, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI21361497, Length=377, Percent_Identity=31.2997347480106, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI226958414, Length=336, Percent_Identity=33.0357142857143, Blast_Score=188, Evalue=9e-48,
Organism=Homo sapiens, GI7656849, Length=384, Percent_Identity=29.9479166666667, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI4501857, Length=385, Percent_Identity=28.8311688311688, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI4503943, Length=288, Percent_Identity=29.5138888888889, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI7669494, Length=274, Percent_Identity=28.8321167883212, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI48976061, Length=350, Percent_Identity=24, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI211971008, Length=350, Percent_Identity=24, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI87081958, Length=346, Percent_Identity=28.9017341040462, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1786223, Length=373, Percent_Identity=25.201072386059, Blast_Score=126, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17534899, Length=403, Percent_Identity=33.4987593052109, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17569725, Length=375, Percent_Identity=34.9333333333333, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17570075, Length=397, Percent_Identity=34.2569269521411, Blast_Score=210, Evalue=9e-55,
Organism=Caenorhabditis elegans, GI17533517, Length=374, Percent_Identity=32.620320855615, Blast_Score=201, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17508101, Length=374, Percent_Identity=29.9465240641711, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17506239, Length=376, Percent_Identity=30.0531914893617, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI71985184, Length=369, Percent_Identity=30.8943089430894, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17538396, Length=382, Percent_Identity=31.151832460733, Blast_Score=181, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI71990804, Length=297, Percent_Identity=34.006734006734, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17551932, Length=376, Percent_Identity=27.9255319148936, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71985192, Length=326, Percent_Identity=29.1411042944785, Blast_Score=147, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI17505929, Length=363, Percent_Identity=28.6501377410468, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=31.8965517241379, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI71982178, Length=279, Percent_Identity=26.1648745519713, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17534353, Length=382, Percent_Identity=26.9633507853403, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17562446, Length=359, Percent_Identity=23.3983286908078, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356377, Length=379, Percent_Identity=36.1477572559367, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24660351, Length=379, Percent_Identity=35.0923482849604, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI24666513, Length=376, Percent_Identity=34.5744680851064, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24646207, Length=374, Percent_Identity=33.1550802139037, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI281363737, Length=372, Percent_Identity=33.0645161290323, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI21355753, Length=388, Percent_Identity=31.9587628865979, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI19920834, Length=386, Percent_Identity=27.2020725388601, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42512; Mature: 42512

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLLEQINAARKWNDDERAVIDQVERMVEKVIRPNAAAYDESGDFPWANVEAINELGLNT
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCE
IFLPEAYGGMPMSYALYLEIVSIISEACASTGIIYATNFHGMKPLVEFGDDAQRERLLPR
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHCCCCHHHHHHHHH
IAAGGLGALAITEPSAGSDATSMKTSFSPDGDEIVVNGSKIFISNGDVADLYLLFGKWSQ
HHCCCCCEEEEECCCCCCCCHHCCCCCCCCCCEEEEECCEEEEECCCHHHHHHHHHCCCC
IEDPKKAISALILEKGAEGFEVVSKERKMGHNASSTCTLSFDNVRVPRANLLKEPGDGLS
CCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEECCEECCHHHHHCCCCCCHH
ILLASLNHSRPSVAAHARGIARAAFRDMVSYGNDRVQSGRKILDFQGNQFTLADLACELA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEECCCCEEEHHHHHHHHH
MLETWIDHVASLVDSKVSDIGLAASVAKLRASDLAMKMAIECVQMHGGYGYCRDYRAERL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MRDAKITQIWEGTNQIHRQLIGRSFRTK
HHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQLLEQINAARKWNDDERAVIDQVERMVEKVIRPNAAAYDESGDFPWANVEAINELGLNT
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCE
IFLPEAYGGMPMSYALYLEIVSIISEACASTGIIYATNFHGMKPLVEFGDDAQRERLLPR
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHCCCCHHHHHHHHH
IAAGGLGALAITEPSAGSDATSMKTSFSPDGDEIVVNGSKIFISNGDVADLYLLFGKWSQ
HHCCCCCEEEEECCCCCCCCHHCCCCCCCCCCEEEEECCEEEEECCCHHHHHHHHHCCCC
IEDPKKAISALILEKGAEGFEVVSKERKMGHNASSTCTLSFDNVRVPRANLLKEPGDGLS
CCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEECCEECCHHHHHCCCCCCHH
ILLASLNHSRPSVAAHARGIARAAFRDMVSYGNDRVQSGRKILDFQGNQFTLADLACELA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEECCCCEEEHHHHHHHHH
MLETWIDHVASLVDSKVSDIGLAASVAKLRASDLAMKMAIECVQMHGGYGYCRDYRAERL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MRDAKITQIWEGTNQIHRQLIGRSFRTK
HHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]