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The map label for this gene is nagA [H]

Identifier: 110635196

GI number: 110635196

Start: 3114158

End: 3115339

Strand: Reverse

Name: nagA [H]

Synonym: Meso_2863

Alternate gene names: 110635196

Gene position: 3115339-3114158 (Counterclockwise)

Preceding gene: 110635197

Following gene: 110635195

Centisome position: 70.6

GC content: 64.55

Gene sequence:

>1182_bases
ATGGACATAACCATCCTCGCCGGGGCGCGCCTGTTTGATGGTGAGCGCTTCATCGACCGGCACGCTCTCGTCGTGGTGGC
TGGTCGCGTTAGGGATATCGTGCCTGAAGCGGAACTCGCCGGCAGACAGGACGTGACGCGGCTCGACGGCGGAATTCTGG
CGCCAGGCTTCATCGACGTGCAGGTGAATGGCGGCGGCGGGCGTCTTCTCAACAATGATCCGACGCCTGAAACCTTCTTC
GTTATAGCGCGGGCGCATCGGCAATACGGCACGACGGCACTGCTGCCCACTCTTGTCACCGATACGCGTGAGGTAACGCG
CAGGGCTGTCGAGGCCGCAACCGAAGCCGCCAAGGCAGACGAGGGCGTGCTCGGTATCCATCTAGAGGGTCCACATCTGG
CGCCAGCCCGGCGCGGCGCGCATCTGGCCGATCTCATGCGGCCGATGGACGATGAAGATCTCGATCTCTTGTGCCGCGCG
GCGGGCGCCATGCCGGTGCTTCACGTTACCCTTGCCGCAGAGCAGGTGACGCCGTGGCAGGTGGAGCGGCTTGCCAAGGC
CGGCATTATCGTGAGCCTCGGCCATACGGATTGCACGAGCGAGGATGCGCTGCGCCTGTTCAATGCGGGCGCGCGGGGAA
TTACGCATCTATATAACGCGATGAGCGCGCTGTCGCACCGCGCGCCGGGGCTGGTGGGTGCTGCCCTTGATGCCGGTGAC
GTCTGGGGCGGCATCATTGCCGATGGGCATCATGTCGACCCGGCGGCACTTCGTCTTGCACTGCGTGCCAAACGCGGGCC
GGCCAAGCTTTTCCACGTAACCGACGCGATGGCGCTCGTCGGAAGCGAGGCCGAGAGTTTCGAGTTGAACGGCCGTACGG
TGCGGCGTGAGCCGGGCGAGGTCTGCTCGAAGCTGGTGCTCGAAGACGGAACATTGGCGGGATCCGACCTTGATATGGCG
ACGGGCGTGCGTTTTGGCGTGCAGATGCTGGAGCTCTCGGTGGAAGAGTCGCTCAGGATGGCCTGCGCCTATCCCGCCAC
CTATCTCGGGATCGGCAGTGAGCGCGGATATTTGAAGCTGGGCCGCCGGGCTGATTGCATCCACCTTTCGGAGGATCTGC
GCGTGCAGCAGGTATGGATGGCGGGCAAGGCGCGCTTCGGCAGAATGGCGGCATGGGCCTAG

Upstream 100 bases:

>100_bases
CACTTGCCGCCTATTACCGGCTGGTGGAGCGGCTTGCGCGCGAGCGCGGATTCAACCCCGATACGCCAGACAAGCTTAAG
AAGGTGACGGAGACGATCTG

Downstream 100 bases:

>100_bases
GCCAGAGTGAAGAGTGGCGCTAAATTGCGCCGCTCACCAGTAAGAGGCATTCATGAATTTCATTCCGGATACCGCAATAA
TCCTGCAATTTGCGATAGCG

Product: N-acetylglucosamine 6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MDITILAGARLFDGERFIDRHALVVVAGRVRDIVPEAELAGRQDVTRLDGGILAPGFIDVQVNGGGGRLLNNDPTPETFF
VIARAHRQYGTTALLPTLVTDTREVTRRAVEAATEAAKADEGVLGIHLEGPHLAPARRGAHLADLMRPMDDEDLDLLCRA
AGAMPVLHVTLAAEQVTPWQVERLAKAGIIVSLGHTDCTSEDALRLFNAGARGITHLYNAMSALSHRAPGLVGAALDAGD
VWGGIIADGHHVDPAALRLALRAKRGPAKLFHVTDAMALVGSEAESFELNGRTVRREPGEVCSKLVLEDGTLAGSDLDMA
TGVRFGVQMLELSVEESLRMACAYPATYLGIGSERGYLKLGRRADCIHLSEDLRVQQVWMAGKARFGRMAAWA

Sequences:

>Translated_393_residues
MDITILAGARLFDGERFIDRHALVVVAGRVRDIVPEAELAGRQDVTRLDGGILAPGFIDVQVNGGGGRLLNNDPTPETFF
VIARAHRQYGTTALLPTLVTDTREVTRRAVEAATEAAKADEGVLGIHLEGPHLAPARRGAHLADLMRPMDDEDLDLLCRA
AGAMPVLHVTLAAEQVTPWQVERLAKAGIIVSLGHTDCTSEDALRLFNAGARGITHLYNAMSALSHRAPGLVGAALDAGD
VWGGIIADGHHVDPAALRLALRAKRGPAKLFHVTDAMALVGSEAESFELNGRTVRREPGEVCSKLVLEDGTLAGSDLDMA
TGVRFGVQMLELSVEESLRMACAYPATYLGIGSERGYLKLGRRADCIHLSEDLRVQQVWMAGKARFGRMAAWA
>Mature_393_residues
MDITILAGARLFDGERFIDRHALVVVAGRVRDIVPEAELAGRQDVTRLDGGILAPGFIDVQVNGGGGRLLNNDPTPETFF
VIARAHRQYGTTALLPTLVTDTREVTRRAVEAATEAAKADEGVLGIHLEGPHLAPARRGAHLADLMRPMDDEDLDLLCRA
AGAMPVLHVTLAAEQVTPWQVERLAKAGIIVSLGHTDCTSEDALRLFNAGARGITHLYNAMSALSHRAPGLVGAALDAGD
VWGGIIADGHHVDPAALRLALRAKRGPAKLFHVTDAMALVGSEAESFELNGRTVRREPGEVCSKLVLEDGTLAGSDLDMA
TGVRFGVQMLELSVEESLRMACAYPATYLGIGSERGYLKLGRRADCIHLSEDLRVQQVWMAGKARFGRMAAWA

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=420, Percent_Identity=34.7619047619048, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI224922791, Length=424, Percent_Identity=34.6698113207547, Blast_Score=155, Evalue=6e-38,
Organism=Escherichia coli, GI1786892, Length=382, Percent_Identity=40.0523560209424, Blast_Score=251, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI17553768, Length=355, Percent_Identity=30.9859154929577, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI19920392, Length=347, Percent_Identity=35.4466858789625, Blast_Score=171, Evalue=9e-43,
Organism=Drosophila melanogaster, GI281361140, Length=360, Percent_Identity=34.4444444444444, Blast_Score=168, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 42106; Mature: 42106

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDITILAGARLFDGERFIDRHALVVVAGRVRDIVPEAELAGRQDVTRLDGGILAPGFIDV
CCEEEEECCEEECCHHHHCCCEEEEEECHHHHHCCCHHHCCCCCHHHHCCCEECCCEEEE
QVNGGGGRLLNNDPTPETFFVIARAHRQYGTTALLPTLVTDTREVTRRAVEAATEAAKAD
EEECCCCEECCCCCCCCEEEEEEEHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCC
EGVLGIHLEGPHLAPARRGAHLADLMRPMDDEDLDLLCRAAGAMPVLHVTLAAEQVTPWQ
CCEEEEEECCCCCCHHHCCCHHHHHHCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCHHH
VERLAKAGIIVSLGHTDCTSEDALRLFNAGARGITHLYNAMSALSHRAPGLVGAALDAGD
HHHHHHCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCC
VWGGIIADGHHVDPAALRLALRAKRGPAKLFHVTDAMALVGSEAESFELNGRTVRREPGE
CCCCEECCCCCCCHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCCEEEECCCEECCCHHH
VCSKLVLEDGTLAGSDLDMATGVRFGVQMLELSVEESLRMACAYPATYLGIGSERGYLKL
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCEEE
GRRADCIHLSEDLRVQQVWMAGKARFGRMAAWA
CCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDITILAGARLFDGERFIDRHALVVVAGRVRDIVPEAELAGRQDVTRLDGGILAPGFIDV
CCEEEEECCEEECCHHHHCCCEEEEEECHHHHHCCCHHHCCCCCHHHHCCCEECCCEEEE
QVNGGGGRLLNNDPTPETFFVIARAHRQYGTTALLPTLVTDTREVTRRAVEAATEAAKAD
EEECCCCEECCCCCCCCEEEEEEEHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCC
EGVLGIHLEGPHLAPARRGAHLADLMRPMDDEDLDLLCRAAGAMPVLHVTLAAEQVTPWQ
CCEEEEEECCCCCCHHHCCCHHHHHHCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCHHH
VERLAKAGIIVSLGHTDCTSEDALRLFNAGARGITHLYNAMSALSHRAPGLVGAALDAGD
HHHHHHCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCC
VWGGIIADGHHVDPAALRLALRAKRGPAKLFHVTDAMALVGSEAESFELNGRTVRREPGE
CCCCEECCCCCCCHHHHHHHHHCCCCCCEEEEHHHHHHHHCCCCCEEEECCCEECCCHHH
VCSKLVLEDGTLAGSDLDMATGVRFGVQMLELSVEESLRMACAYPATYLGIGSERGYLKL
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCEEE
GRRADCIHLSEDLRVQQVWMAGKARFGRMAAWA
CCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]