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The map label for this gene is aglR [H]

Identifier: 110635187

GI number: 110635187

Start: 3104690

End: 3105865

Strand: Reverse

Name: aglR [H]

Synonym: Meso_2854

Alternate gene names: 110635187

Gene position: 3105865-3104690 (Counterclockwise)

Preceding gene: 110635195

Following gene: 110635186

Centisome position: 70.39

GC content: 60.29

Gene sequence:

>1176_bases
GTGCAGCGTGGCGCAGGCTTGATTTACCCGTCCTTTCCTACGAATAATGTCCAAAGCGCTTTGAACGAGGTGGCGTTGGC
ACGCGAGACGATTACCCTGCGCAGGCTCGCGGAGGTGCTGGGCCTGTCCCAGACCACCGTGTCGCGCGCGCTCAACGGAT
TTCCGGAGGTGAACGAGGCAACGCGGGCACGCGTCATCGAGGCCGCGCAACGGCTTAATTACCGCCCAAGCGCCAGCGCG
GCCAGTCTCGCAACCGGTAAAGCGCGCACGATCGGTCATGTGGTGACGCTCGGCGATCACATGATGATCAATCCGCATTT
CACCGATTTCGTGGCAGGGGCTGGAGAGGTCTATGCCCGCTTCGGCTACGAGATGCTGCTTCGCATCACAGGTAGCGAGG
GCGAGCAGGACGTTTACCGCGACCTTATCAGCCGCCGTCGCGTCGACGGGGTCGTGGTGCACGGGCCAAAGACAAGGGAT
CCACGTATCCCTTTCCTCAGGAAACTTGGCATCCCGTTCGTCGTGCACGGCCGTTGCGAAGAGGATCCCGCAAGTTACAG
TTGGATCGATGTCAACAACAGGCGCGCATTCATGCGGGCCTGCAACTTCCTTATCGATCTCGGCCATCGCCGCATCGGGC
TTATAAACGGTATCGAGACGATGAACTTTGCGGATCGTCGCCGGCAGGGCTATGAGGCGGCGCTCGCGGCGCGGGGCATC
GATCTGGATACGTCGATAATGTTCAGCGCGGACATGATCGAACCCCATGGATATCGCGCGGCCGCCCAGATGCTTTCCAG
TCGCAAACCTCCAACGGCGGTTTTGGTCTCCAGCATTCTTCCCGCCATAGGCGTGATGCGCGCTTTGGCGGAACGGGAGT
TGCGGCCCGCCACAGACCTCTCGATCATCGTATTCGACGATTGCCTTTCCTTCCTGCAGCCAGGGAATGAAGCCGTTTCT
GGCGCTATCCCTTTTTTCACGGCAATGCGCTCCTCCATGCGCCTCGCCGGCCGCCGCGTTGCCGAGCTCTTGATCGAGCA
AATAGAGGGGCAGCACAGTGCTCCCAAGCACGAATTGTGGGAGGCCGAACTTGTCATCGGCCATACGACGGGGCCATGCG
CTCCGGCTGAATCTCAGGTTCCCGTTCGAGTCAAGCCTTTCCGGAGATATTCTTGA

Upstream 100 bases:

>100_bases
ACATCCCGCCTCCGCCGAGCCGAGTCAAGCGGGCGAAAACGCGGACCATTTTTGCGGCAGTGCGAAAACGGCGGGGTGAT
TTCGCGGCTCCAGTGAGCAG

Downstream 100 bases:

>100_bases
AATTCGAACGGCGGTTTCGGACGGGGGCTGCCAAAAGCAAGACAAATACGACATTCCGCGCTTTAATAAGCTTATAAAAC
TTTAATATTGCAACTCTGTC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MQRGAGLIYPSFPTNNVQSALNEVALARETITLRRLAEVLGLSQTTVSRALNGFPEVNEATRARVIEAAQRLNYRPSASA
ASLATGKARTIGHVVTLGDHMMINPHFTDFVAGAGEVYARFGYEMLLRITGSEGEQDVYRDLISRRRVDGVVVHGPKTRD
PRIPFLRKLGIPFVVHGRCEEDPASYSWIDVNNRRAFMRACNFLIDLGHRRIGLINGIETMNFADRRRQGYEAALAARGI
DLDTSIMFSADMIEPHGYRAAAQMLSSRKPPTAVLVSSILPAIGVMRALAERELRPATDLSIIVFDDCLSFLQPGNEAVS
GAIPFFTAMRSSMRLAGRRVAELLIEQIEGQHSAPKHELWEAELVIGHTTGPCAPAESQVPVRVKPFRRYS

Sequences:

>Translated_391_residues
MQRGAGLIYPSFPTNNVQSALNEVALARETITLRRLAEVLGLSQTTVSRALNGFPEVNEATRARVIEAAQRLNYRPSASA
ASLATGKARTIGHVVTLGDHMMINPHFTDFVAGAGEVYARFGYEMLLRITGSEGEQDVYRDLISRRRVDGVVVHGPKTRD
PRIPFLRKLGIPFVVHGRCEEDPASYSWIDVNNRRAFMRACNFLIDLGHRRIGLINGIETMNFADRRRQGYEAALAARGI
DLDTSIMFSADMIEPHGYRAAAQMLSSRKPPTAVLVSSILPAIGVMRALAERELRPATDLSIIVFDDCLSFLQPGNEAVS
GAIPFFTAMRSSMRLAGRRVAELLIEQIEGQHSAPKHELWEAELVIGHTTGPCAPAESQVPVRVKPFRRYS
>Mature_391_residues
MQRGAGLIYPSFPTNNVQSALNEVALARETITLRRLAEVLGLSQTTVSRALNGFPEVNEATRARVIEAAQRLNYRPSASA
ASLATGKARTIGHVVTLGDHMMINPHFTDFVAGAGEVYARFGYEMLLRITGSEGEQDVYRDLISRRRVDGVVVHGPKTRD
PRIPFLRKLGIPFVVHGRCEEDPASYSWIDVNNRRAFMRACNFLIDLGHRRIGLINGIETMNFADRRRQGYEAALAARGI
DLDTSIMFSADMIEPHGYRAAAQMLSSRKPPTAVLVSSILPAIGVMRALAERELRPATDLSIIVFDDCLSFLQPGNEAVS
GAIPFFTAMRSSMRLAGRRVAELLIEQIEGQHSAPKHELWEAELVIGHTTGPCAPAESQVPVRVKPFRRYS

Specific function: Probable regulatory protein for the binding-protein- dependent transport system for alpha-glucosides such as sucrose, maltose and trehalose [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=346, Percent_Identity=30.3468208092486, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1790194, Length=289, Percent_Identity=31.8339100346021, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787948, Length=278, Percent_Identity=29.8561151079137, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1789202, Length=289, Percent_Identity=30.1038062283737, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787580, Length=285, Percent_Identity=24.5614035087719, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1789068, Length=281, Percent_Identity=27.4021352313167, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1786540, Length=360, Percent_Identity=26.6666666666667, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789456, Length=287, Percent_Identity=29.2682926829268, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788474, Length=280, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 43176; Mature: 43176

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRGAGLIYPSFPTNNVQSALNEVALARETITLRRLAEVLGLSQTTVSRALNGFPEVNEA
CCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHH
TRARVIEAAQRLNYRPSASAASLATGKARTIGHVVTLGDHMMINPHFTDFVAGAGEVYAR
HHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHEEEEECCEEEECCCHHHHHHCCHHHHHH
FGYEMLLRITGSEGEQDVYRDLISRRRVDGVVVHGPKTRDPRIPFLRKLGIPFVVHGRCE
HHHEEEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHCCCCEEEECCCC
EDPASYSWIDVNNRRAFMRACNFLIDLGHRRIGLINGIETMNFADRRRQGYEAALAARGI
CCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEHHCCCHHCCHHHHHHHHHHHHHHHCCC
DLDTSIMFSADMIEPHGYRAAAQMLSSRKPPTAVLVSSILPAIGVMRALAERELRPATDL
CCCCHHEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SIIVFDDCLSFLQPGNEAVSGAIPFFTAMRSSMRLAGRRVAELLIEQIEGQHSAPKHELW
EEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCC
EAELVIGHTTGPCAPAESQVPVRVKPFRRYS
EEEEEEEECCCCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure
MQRGAGLIYPSFPTNNVQSALNEVALARETITLRRLAEVLGLSQTTVSRALNGFPEVNEA
CCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHH
TRARVIEAAQRLNYRPSASAASLATGKARTIGHVVTLGDHMMINPHFTDFVAGAGEVYAR
HHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHEEEEECCEEEECCCHHHHHHCCHHHHHH
FGYEMLLRITGSEGEQDVYRDLISRRRVDGVVVHGPKTRDPRIPFLRKLGIPFVVHGRCE
HHHEEEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHCCCCEEEECCCC
EDPASYSWIDVNNRRAFMRACNFLIDLGHRRIGLINGIETMNFADRRRQGYEAALAARGI
CCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEHHCCCHHCCHHHHHHHHHHHHHHHCCC
DLDTSIMFSADMIEPHGYRAAAQMLSSRKPPTAVLVSSILPAIGVMRALAERELRPATDL
CCCCHHEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SIIVFDDCLSFLQPGNEAVSGAIPFFTAMRSSMRLAGRRVAELLIEQIEGQHSAPKHELW
EEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCC
EAELVIGHTTGPCAPAESQVPVRVKPFRRYS
EEEEEEEECCCCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]