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The map label for this gene is ligC [H]

Identifier: 110635034

GI number: 110635034

Start: 2933699

End: 2934796

Strand: Reverse

Name: ligC [H]

Synonym: Meso_2700

Alternate gene names: 110635034

Gene position: 2934796-2933699 (Counterclockwise)

Preceding gene: 110635035

Following gene: 110635033

Centisome position: 66.51

GC content: 64.03

Gene sequence:

>1098_bases
ATGGCCGGACGGCACGGACGCAATTCACCGGAGACAATAAACGCCGCGGCGGCGCTCGAAATGCCGATACCGCCTATGGA
GGCGAAGACGGTGGAGACCCTGCCCGAGGAGCCGGGCTGGGACTTTGAGCCGAAATGGGATGGCTTCCGCTGCCTTGCCC
ATCGCGATGGCGATAAGATCGAGCTTTACGCCAAATCCGGCAAGCCGCTCGGCCGTTACTTTCCCGAGGTCGTGGAAATT
GTGCGCGCCCTGCCTGGCCGAAAATTCATTCTGGATGGCGAACTGGTCATCGCCCAGGGCGAGGCGCTTTCCTTCGATGC
CCTGCAACTGCGGTTGCACCCGGCGGAAAGCCGGATACGCAAGCTCGCGCGCGAGACACCGGCGATGCTGATCCTCTTCG
ACATGCTGATGAAGCCTGACGGCGAAAGCCTCATGACGGCGCCCCTGACGGCGCGGCGCAGCGCATTGGAAAGCTTTCTG
GCGCAGGCGGTGGTTTCCGGTATTCGGCTTTCGCCCCATACGCGCGACCGAAGAGAAGCCGAAGCCTGGCTGGAGGGCGC
GGGCGGAGCGCTCGATGGAGTCATCGCGAAGAAGTTCGACGGTGCATATGAAAGTGGCGAGCGCGCCATGCTGAAGGTCA
AGCGCATCCGCTCTGCCGATTGCGTCGTGGGCGGCTTCCGCTACGGGAAAGACAGCACTCTCGTCGGCTCGCTCCTGCTC
GGGCTCTTCAACGGTGAGGGGAAGCTCGACCATGTCGGTTTCACCTCCATGATCAGCAATGAGGAGCGGCCGGCTTTGAC
GCGCCGGCTGGAAAAGCTCAAGGGACCGCCTGGCTTTACCGGGAAGGCGCCGGGCGGGCCTAGCCGCTGGTCGACCGAGC
GCAGCAGTGAATGGGAGCCGCTCCGGCACGAGCTCGTGGTGGAAGTCGCCTACGACCAGGTGACGGGAGATCGCTTCCGC
CACGGCACCAGGCTTTTGCGCTGGCGCCCGGACAAAGCCCCGCATCAATGCACATTCGAACAGCTTGAGCATGAGGCCCG
CCCAGGCAAGTTGATCGAGGAGGTGATCCGCAGGCGCCGGGACGCGCGCCGTGAATGA

Upstream 100 bases:

>100_bases
TGCGGGCGGGCTGATGAAAATCGGCGTTCCCGCACCAACTCCCTTCCGGCGCGGGAACGCCGCCACAACGCCGGCGTTTC
TGCCCCGAAAGGGTGCAGCC

Downstream 100 bases:

>100_bases
CCTCTGCCGCAATGAAACAAGGCAGTACGGGTCATAAGATCAGAACCTCCCCCGCACGGTCGGCCTAAGGACAATCCGGC
ACCAGAGGAAGCGCAATCGT

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MAGRHGRNSPETINAAAALEMPIPPMEAKTVETLPEEPGWDFEPKWDGFRCLAHRDGDKIELYAKSGKPLGRYFPEVVEI
VRALPGRKFILDGELVIAQGEALSFDALQLRLHPAESRIRKLARETPAMLILFDMLMKPDGESLMTAPLTARRSALESFL
AQAVVSGIRLSPHTRDRREAEAWLEGAGGALDGVIAKKFDGAYESGERAMLKVKRIRSADCVVGGFRYGKDSTLVGSLLL
GLFNGEGKLDHVGFTSMISNEERPALTRRLEKLKGPPGFTGKAPGGPSRWSTERSSEWEPLRHELVVEVAYDQVTGDRFR
HGTRLLRWRPDKAPHQCTFEQLEHEARPGKLIEEVIRRRRDARRE

Sequences:

>Translated_365_residues
MAGRHGRNSPETINAAAALEMPIPPMEAKTVETLPEEPGWDFEPKWDGFRCLAHRDGDKIELYAKSGKPLGRYFPEVVEI
VRALPGRKFILDGELVIAQGEALSFDALQLRLHPAESRIRKLARETPAMLILFDMLMKPDGESLMTAPLTARRSALESFL
AQAVVSGIRLSPHTRDRREAEAWLEGAGGALDGVIAKKFDGAYESGERAMLKVKRIRSADCVVGGFRYGKDSTLVGSLLL
GLFNGEGKLDHVGFTSMISNEERPALTRRLEKLKGPPGFTGKAPGGPSRWSTERSSEWEPLRHELVVEVAYDQVTGDRFR
HGTRLLRWRPDKAPHQCTFEQLEHEARPGKLIEEVIRRRRDARRE
>Mature_364_residues
AGRHGRNSPETINAAAALEMPIPPMEAKTVETLPEEPGWDFEPKWDGFRCLAHRDGDKIELYAKSGKPLGRYFPEVVEIV
RALPGRKFILDGELVIAQGEALSFDALQLRLHPAESRIRKLARETPAMLILFDMLMKPDGESLMTAPLTARRSALESFLA
QAVVSGIRLSPHTRDRREAEAWLEGAGGALDGVIAKKFDGAYESGERAMLKVKRIRSADCVVGGFRYGKDSTLVGSLLLG
LFNGEGKLDHVGFTSMISNEERPALTRRLEKLKGPPGFTGKAPGGPSRWSTERSSEWEPLRHELVVEVAYDQVTGDRFRH
GTRLLRWRPDKAPHQCTFEQLEHEARPGKLIEEVIRRRRDARRE

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Drosophila melanogaster, GI85815841, Length=273, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022865
- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 40848; Mature: 40717

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS00697 DNA_LIGASE_A1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRHGRNSPETINAAAALEMPIPPMEAKTVETLPEEPGWDFEPKWDGFRCLAHRDGDKI
CCCCCCCCCCCCCCHHEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEE
ELYAKSGKPLGRYFPEVVEIVRALPGRKFILDGELVIAQGEALSFDALQLRLHPAESRIR
EEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEEEEEECCHHHHHH
KLARETPAMLILFDMLMKPDGESLMTAPLTARRSALESFLAQAVVSGIRLSPHTRDRREA
HHHHHCCHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
EAWLEGAGGALDGVIAKKFDGAYESGERAMLKVKRIRSADCVVGGFRYGKDSTLVGSLLL
HHHHHCCCCHHHHHHHHHHCCCHHCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHH
GLFNGEGKLDHVGFTSMISNEERPALTRRLEKLKGPPGFTGKAPGGPSRWSTERSSEWEP
HHHCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCH
LRHELVVEVAYDQVTGDRFRHGTRLLRWRPDKAPHQCTFEQLEHEARPGKLIEEVIRRRR
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHH
DARRE
HCCCC
>Mature Secondary Structure 
AGRHGRNSPETINAAAALEMPIPPMEAKTVETLPEEPGWDFEPKWDGFRCLAHRDGDKI
CCCCCCCCCCCCCHHEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEE
ELYAKSGKPLGRYFPEVVEIVRALPGRKFILDGELVIAQGEALSFDALQLRLHPAESRIR
EEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEEEEEECCHHHHHH
KLARETPAMLILFDMLMKPDGESLMTAPLTARRSALESFLAQAVVSGIRLSPHTRDRREA
HHHHHCCHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
EAWLEGAGGALDGVIAKKFDGAYESGERAMLKVKRIRSADCVVGGFRYGKDSTLVGSLLL
HHHHHCCCCHHHHHHHHHHCCCHHCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHH
GLFNGEGKLDHVGFTSMISNEERPALTRRLEKLKGPPGFTGKAPGGPSRWSTERSSEWEP
HHHCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCH
LRHELVVEVAYDQVTGDRFRHGTRLLRWRPDKAPHQCTFEQLEHEARPGKLIEEVIRRRR
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHH
DARRE
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]