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The map label for this gene is allB [H]

Identifier: 110634975

GI number: 110634975

Start: 2852202

End: 2853560

Strand: Reverse

Name: allB [H]

Synonym: Meso_2641

Alternate gene names: 110634975

Gene position: 2853560-2852202 (Counterclockwise)

Preceding gene: 110634976

Following gene: 110634974

Centisome position: 64.67

GC content: 62.47

Gene sequence:

>1359_bases
ATGTCCGACTTTGATCTCGTGCTGTCCGGCAGGGTCGTATTGCCTGATGTGGTTGTTGAGAACGGTTACGTAGCGGTTCG
CGACGGTAGGGTGGAGCATGTCGGTAAAGGCGATGCGCCATCGGCGCGGGAGCGACACGTTCTTGGTAATGCCCTGATCC
TGCCCGGTGCGATCGACGCTCAGGTGCATTCCCTGAGCCAGAAGCATCAGGAGGATTTCATCTGGTCCACCCGCTCCGCA
GCCGCGGGCGGCGTCACCACCATTGTCGATATGCCATATGATGAGGGCAATCTGGTCTGTTCCGCCGCGGCCGTTCGCAA
GAAGGTCGATCATGCGAGCTCGCAGGCGCGCGTGGACTTCGCCCTATACGGCACGATCGATCCGATGGAGGGCCCGGCAC
GCATCGCCGAACAGGCCGAAGCTGGTGTGGCCGCATTCAAGTTTTCCACCTTCGGCACCGATCCAGTGCGCTTTCCGCGC
ATTTCCCCCGCCTTGCTTGAGGAGTGTTTTGTTGCGGTCGCCAAGACCGGTCTGACCGCCGGCGTCCACAACGAAGACGA
CGAGATGGTGCACCACGCCATGGCCAGGGTGAAGGCTGCGGGCATTTCCGATTATCGCGCCCATGCAATGAGCCGGCCGC
CGTTAACCGAGCTTCTTGCCACCCTTCAGATCTACGAGATCGGCGCGCAGACGGGATGCCCCGCTCATGTGGTCCATTGT
TCGCTGTCCCGTGGATACGAGATCGCCCGCAGCTATCGCGATCAGGGCTACGCCGCCACCATTGAGGCCTGCATCCATTA
TCTGACGCTGGACGAGGACAATGACGTCAAGCGTCTTGGCGGCAAGGCCAAGATCAATCCGCCGCTCCGGCCCCGCGCCG
AGGTCGAAAAGCTCTGGGAACATGTGCGCCGGGGCAACGTCACCCTCGTCTCCACCGATCATGTGAGCTGGTCGGAAAAC
CGCAAGAACAATTCGGACATGCTGGCCAATTCATCGGGTGTTCCCGGCCTCGAAGTTATGGTGCCGCTTTTCGTCAAGGG
CGCGCTGGCGCGCGACATTCCCCTGACCTGGGCCGCGAAGCTCATGGCCGAGAGCCCGGCGAGGCACTTCCGGATCGATC
ATGCCAAGGGAGCGCTGACCGCCGGGCGCGATGCCGATATTACCGTGCTGTTCCCGAGACCCAAGATCTATGACGCTGCC
GAAAGCGGCCACAACGTCGTCGGCTGGTCTCCCTATAACGGCATCGAACTGCCCTGGACCGTTGGTCTGACCTATCTGCG
TGGGCGGCAGGTCTTCGACGGCACCGAAACGGCGGCCCCCGGTACTGGCCGGTTCGTGCGCCCCGAGGCGCGCCACTGA

Upstream 100 bases:

>100_bases
GTTCGGCTATTGGGATTTCCCTCCGCGATATCTGTCGGCCTAGGGTGGCCGGAAATCAACCTTCCACCCATGCCTGCCGA
TCTGGGAGCGAAAGCCATAA

Downstream 100 bases:

>100_bases
TGCCGCGTTTCGCGCCTGCCTTTGCTCGCGCTCCTGGCCTCTCGCTCTTCGTAACGGGGCCGGAGGGCATGCCGGCATGA
TCCCGAATTCCCCCATTCGC

Product: amidohydrolase

Products: NA

Alternate protein names: Allantoin-utilizing enzyme [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSDFDLVLSGRVVLPDVVVENGYVAVRDGRVEHVGKGDAPSARERHVLGNALILPGAIDAQVHSLSQKHQEDFIWSTRSA
AAGGVTTIVDMPYDEGNLVCSAAAVRKKVDHASSQARVDFALYGTIDPMEGPARIAEQAEAGVAAFKFSTFGTDPVRFPR
ISPALLEECFVAVAKTGLTAGVHNEDDEMVHHAMARVKAAGISDYRAHAMSRPPLTELLATLQIYEIGAQTGCPAHVVHC
SLSRGYEIARSYRDQGYAATIEACIHYLTLDEDNDVKRLGGKAKINPPLRPRAEVEKLWEHVRRGNVTLVSTDHVSWSEN
RKNNSDMLANSSGVPGLEVMVPLFVKGALARDIPLTWAAKLMAESPARHFRIDHAKGALTAGRDADITVLFPRPKIYDAA
ESGHNVVGWSPYNGIELPWTVGLTYLRGRQVFDGTETAAPGTGRFVRPEARH

Sequences:

>Translated_452_residues
MSDFDLVLSGRVVLPDVVVENGYVAVRDGRVEHVGKGDAPSARERHVLGNALILPGAIDAQVHSLSQKHQEDFIWSTRSA
AAGGVTTIVDMPYDEGNLVCSAAAVRKKVDHASSQARVDFALYGTIDPMEGPARIAEQAEAGVAAFKFSTFGTDPVRFPR
ISPALLEECFVAVAKTGLTAGVHNEDDEMVHHAMARVKAAGISDYRAHAMSRPPLTELLATLQIYEIGAQTGCPAHVVHC
SLSRGYEIARSYRDQGYAATIEACIHYLTLDEDNDVKRLGGKAKINPPLRPRAEVEKLWEHVRRGNVTLVSTDHVSWSEN
RKNNSDMLANSSGVPGLEVMVPLFVKGALARDIPLTWAAKLMAESPARHFRIDHAKGALTAGRDADITVLFPRPKIYDAA
ESGHNVVGWSPYNGIELPWTVGLTYLRGRQVFDGTETAAPGTGRFVRPEARH
>Mature_451_residues
SDFDLVLSGRVVLPDVVVENGYVAVRDGRVEHVGKGDAPSARERHVLGNALILPGAIDAQVHSLSQKHQEDFIWSTRSAA
AGGVTTIVDMPYDEGNLVCSAAAVRKKVDHASSQARVDFALYGTIDPMEGPARIAEQAEAGVAAFKFSTFGTDPVRFPRI
SPALLEECFVAVAKTGLTAGVHNEDDEMVHHAMARVKAAGISDYRAHAMSRPPLTELLATLQIYEIGAQTGCPAHVVHCS
LSRGYEIARSYRDQGYAATIEACIHYLTLDEDNDVKRLGGKAKINPPLRPRAEVEKLWEHVRRGNVTLVSTDHVSWSENR
KNNSDMLANSSGVPGLEVMVPLFVKGALARDIPLTWAAKLMAESPARHFRIDHAKGALTAGRDADITVLFPRPKIYDAAE
SGHNVVGWSPYNGIELPWTVGLTYLRGRQVFDGTETAAPGTGRFVRPEARH

Specific function: Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring [H]

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Allantoinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503375, Length=469, Percent_Identity=26.0127931769723, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI4503379, Length=465, Percent_Identity=23.2258064516129, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI4503051, Length=465, Percent_Identity=23.010752688172, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI62422571, Length=466, Percent_Identity=22.9613733905579, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI190194363, Length=468, Percent_Identity=25, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI4503377, Length=467, Percent_Identity=22.6980728051392, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI18105007, Length=405, Percent_Identity=24.1975308641975, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI19923821, Length=468, Percent_Identity=24.1452991452991, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI87082175, Length=460, Percent_Identity=27.6086956521739, Blast_Score=148, Evalue=9e-37,
Organism=Escherichia coli, GI1786722, Length=440, Percent_Identity=27.7272727272727, Blast_Score=142, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71989490, Length=451, Percent_Identity=25.4988913525499, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17539558, Length=465, Percent_Identity=25.3763440860215, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193204318, Length=407, Percent_Identity=24.0786240786241, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6322218, Length=400, Percent_Identity=28.5, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI18859883, Length=423, Percent_Identity=26.241134751773, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24642586, Length=417, Percent_Identity=25.6594724220624, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI221377917, Length=448, Percent_Identity=25.4464285714286, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI17137462, Length=442, Percent_Identity=23.5294117647059, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017593
- InterPro:   IPR006680
- InterPro:   IPR004722
- InterPro:   IPR002195
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.5 [H]

Molecular weight: Translated: 49091; Mature: 48960

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFDLVLSGRVVLPDVVVENGYVAVRDGRVEHVGKGDAPSARERHVLGNALILPGAIDA
CCCCEEEEECCEEECCEEECCCEEEEECCCEEECCCCCCCCHHHHHHCCCEEEECCCCHH
QVHSLSQKHQEDFIWSTRSAAAGGVTTIVDMPYDEGNLVCSAAAVRKKVDHASSQARVDF
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHCCCCCCEEEE
ALYGTIDPMEGPARIAEQAEAGVAAFKFSTFGTDPVRFPRISPALLEECFVAVAKTGLTA
EEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
GVHNEDDEMVHHAMARVKAAGISDYRAHAMSRPPLTELLATLQIYEIGAQTGCPAHVVHC
CCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHEECCCCCCCCEEEEE
SLSRGYEIARSYRDQGYAATIEACIHYLTLDEDNDVKRLGGKAKINPPLRPRAEVEKLWE
ECCCCHHHHHHHHCCCCHHHHHHHHHHEECCCCCCHHHCCCCCCCCCCCCCHHHHHHHHH
HVRRGNVTLVSTDHVSWSENRKNNSDMLANSSGVPGLEVMVPLFVKGALARDIPLTWAAK
HHHCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
LMAESPARHFRIDHAKGALTAGRDADITVLFPRPKIYDAAESGHNVVGWSPYNGIELPWT
HHHCCCHHHEEEECCCCCEECCCCCCEEEECCCCCCCCHHHCCCCEEEECCCCCCCCCHH
VGLTYLRGRQVFDGTETAAPGTGRFVRPEARH
HCHHHHCCCEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDFDLVLSGRVVLPDVVVENGYVAVRDGRVEHVGKGDAPSARERHVLGNALILPGAIDA
CCCEEEEECCEEECCEEECCCEEEEECCCEEECCCCCCCCHHHHHHCCCEEEECCCCHH
QVHSLSQKHQEDFIWSTRSAAAGGVTTIVDMPYDEGNLVCSAAAVRKKVDHASSQARVDF
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHCCCCCCEEEE
ALYGTIDPMEGPARIAEQAEAGVAAFKFSTFGTDPVRFPRISPALLEECFVAVAKTGLTA
EEEECCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
GVHNEDDEMVHHAMARVKAAGISDYRAHAMSRPPLTELLATLQIYEIGAQTGCPAHVVHC
CCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHEECCCCCCCCEEEEE
SLSRGYEIARSYRDQGYAATIEACIHYLTLDEDNDVKRLGGKAKINPPLRPRAEVEKLWE
ECCCCHHHHHHHHCCCCHHHHHHHHHHEECCCCCCHHHCCCCCCCCCCCCCHHHHHHHHH
HVRRGNVTLVSTDHVSWSENRKNNSDMLANSSGVPGLEVMVPLFVKGALARDIPLTWAAK
HHHCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
LMAESPARHFRIDHAKGALTAGRDADITVLFPRPKIYDAAESGHNVVGWSPYNGIELPWT
HHHCCCHHHEEEECCCCCEECCCCCCEEEECCCCCCCCHHHCCCCEEEECCCCCCCCCHH
VGLTYLRGRQVFDGTETAAPGTGRFVRPEARH
HCHHHHCCCEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA