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The map label for this gene is sseA [H]

Identifier: 110634976

GI number: 110634976

Start: 2853941

End: 2854801

Strand: Reverse

Name: sseA [H]

Synonym: Meso_2642

Alternate gene names: 110634976

Gene position: 2854801-2853941 (Counterclockwise)

Preceding gene: 110634977

Following gene: 110634975

Centisome position: 64.7

GC content: 61.79

Gene sequence:

>861_bases
ATGTCAACAAATCAGAAAGCGCCGCCGGTCGTTTCGGCAGAGTGGCTGCTCGCCCATCTTAACGACGCCGATGTGCAGGT
CATCGACGGGACGACGTTCACGCCGGGAACGGGACAGGACGCGCCCACCGCCCATCGGGAGAGACGGATTCCGGGGGCGA
TCTTCTTCGACATAGACCGGATCTGCGATCCGCGGCCCGGACCTCCGAAAAGGATGCTTCCCGGCCCCGAACTTTTCGCA
AGTTTCATGGGCGAACTCGGCCTGCGGGATGACGCGCATCTGGTGGCCTATGACGTCCATGGACTTTATAGCGCTGCCCG
GATCTGGTGGATGTTGCGCATATACGGACACGAACGCATCTCCGTCTTGGACGGCGGCCTGCCGGCCTGGACTGCCGCGG
GCGGCGCGACCGAATCCGGCGAGCCGAAACGCCTTCCGCCGACCCAGTGGCCGGTGCGTCCTCGCGGCGGCTTGGTTCGC
GACTGGCGCCAGATCCTCGACAATATCGATAGCCGGCAGGAAACCGTTGTCGATGTCCGGCCGGCAGAGATGTTCAACGG
AGATACCTCCGCCATCTATCCCGGTGTGCGAAGCGGGCATATACCTGGCTCCGTCAATGTCTCGCAGCGCGATCTCCGGT
TCGAGAACGGAAAATTCCGGAGTATCCAGGACATGCGTGCCATCATTGCTGCGGCAGGCGTCGATCCCGACGGGCCGATG
GTGGCAAGCTGTGGATCGGGCGTCACCGCCTGCGTTTTGTCCCTGGCTATGGAAATCATTCGGGGAGAACCTATTCCGGT
ATATGACGGTTCGTGGGAGGAATGGGGCAGCAGGCCTGATTTACCCGTCGAGATAAACTGA

Upstream 100 bases:

>100_bases
TCGCCGCGTCGGAGCCGGTGCTGCGGGACATTTTGGGTCGCATGGCCGGCGCCGCCGCAAAGCTCGGATAAGGCAGCCGG
AGCAAAACAGGGAGGCTGGA

Downstream 100 bases:

>100_bases
CGTACGGTCATTGGCGGTTTGCCGAAAGCTGCCGTTTGTGCAGCAACTGAGTGCGGCAATACGGGGCCGGAAGCAGCCAT
TCCGCTTTCGGCTTCAGCGG

Product: rhodanese-like protein

Products: NA

Alternate protein names: MST; Rhodanese-like protein [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MSTNQKAPPVVSAEWLLAHLNDADVQVIDGTTFTPGTGQDAPTAHRERRIPGAIFFDIDRICDPRPGPPKRMLPGPELFA
SFMGELGLRDDAHLVAYDVHGLYSAARIWWMLRIYGHERISVLDGGLPAWTAAGGATESGEPKRLPPTQWPVRPRGGLVR
DWRQILDNIDSRQETVVDVRPAEMFNGDTSAIYPGVRSGHIPGSVNVSQRDLRFENGKFRSIQDMRAIIAAAGVDPDGPM
VASCGSGVTACVLSLAMEIIRGEPIPVYDGSWEEWGSRPDLPVEIN

Sequences:

>Translated_286_residues
MSTNQKAPPVVSAEWLLAHLNDADVQVIDGTTFTPGTGQDAPTAHRERRIPGAIFFDIDRICDPRPGPPKRMLPGPELFA
SFMGELGLRDDAHLVAYDVHGLYSAARIWWMLRIYGHERISVLDGGLPAWTAAGGATESGEPKRLPPTQWPVRPRGGLVR
DWRQILDNIDSRQETVVDVRPAEMFNGDTSAIYPGVRSGHIPGSVNVSQRDLRFENGKFRSIQDMRAIIAAAGVDPDGPM
VASCGSGVTACVLSLAMEIIRGEPIPVYDGSWEEWGSRPDLPVEIN
>Mature_285_residues
STNQKAPPVVSAEWLLAHLNDADVQVIDGTTFTPGTGQDAPTAHRERRIPGAIFFDIDRICDPRPGPPKRMLPGPELFAS
FMGELGLRDDAHLVAYDVHGLYSAARIWWMLRIYGHERISVLDGGLPAWTAAGGATESGEPKRLPPTQWPVRPRGGLVRD
WRQILDNIDSRQETVVDVRPAEMFNGDTSAIYPGVRSGHIPGSVNVSQRDLRFENGKFRSIQDMRAIIAAAGVDPDGPMV
ASCGSGVTACVLSLAMEIIRGEPIPVYDGSWEEWGSRPDLPVEIN

Specific function: Transfers a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Its participation in detoxification of cyanide may be small. May be involved in the enhancement of serine sensitivity [H]

COG id: COG2897

COG function: function code P; Rhodanese-related sulfurtransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 rhodanese domains [H]

Homologues:

Organism=Homo sapiens, GI61835204, Length=284, Percent_Identity=38.0281690140845, Blast_Score=195, Evalue=5e-50,
Organism=Homo sapiens, GI194473681, Length=284, Percent_Identity=38.0281690140845, Blast_Score=195, Evalue=5e-50,
Organism=Homo sapiens, GI194473668, Length=284, Percent_Identity=38.0281690140845, Blast_Score=194, Evalue=5e-50,
Organism=Homo sapiens, GI17402865, Length=278, Percent_Identity=35.6115107913669, Blast_Score=174, Evalue=1e-43,
Organism=Escherichia coli, GI87082121, Length=275, Percent_Identity=39.6363636363636, Blast_Score=197, Evalue=5e-52,
Organism=Escherichia coli, GI87081967, Length=256, Percent_Identity=27.34375, Blast_Score=85, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71997283, Length=311, Percent_Identity=27.3311897106109, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17561888, Length=303, Percent_Identity=25.4125412541254, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17559150, Length=250, Percent_Identity=22.4, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17543836, Length=261, Percent_Identity=27.2030651340996, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17543838, Length=261, Percent_Identity=27.2030651340996, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR001307 [H]

Pfam domain/function: PF00581 Rhodanese [H]

EC number: =2.8.1.2 [H]

Molecular weight: Translated: 31269; Mature: 31138

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNQKAPPVVSAEWLLAHLNDADVQVIDGTTFTPGTGQDAPTAHRERRIPGAIFFDIDR
CCCCCCCCCCCCHHHHHHCCCCCCEEEECCCEECCCCCCCCCCHHHHHCCCCEEEEEHHH
ICDPRPGPPKRMLPGPELFASFMGELGLRDDAHLVAYDVHGLYSAARIWWMLRIYGHERI
HCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCEE
SVLDGGLPAWTAAGGATESGEPKRLPPTQWPVRPRGGLVRDWRQILDNIDSRQETVVDVR
EEECCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHEEEECC
PAEMFNGDTSAIYPGVRSGHIPGSVNVSQRDLRFENGKFRSIQDMRAIIAAAGVDPDGPM
HHHHHCCCCCEECCCCCCCCCCCCCCCCHHHEEECCCCCCHHHHHHHHHHHCCCCCCCCE
VASCGSGVTACVLSLAMEIIRGEPIPVYDGSWEEWGSRPDLPVEIN
EECCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCEEEC
>Mature Secondary Structure 
STNQKAPPVVSAEWLLAHLNDADVQVIDGTTFTPGTGQDAPTAHRERRIPGAIFFDIDR
CCCCCCCCCCCHHHHHHCCCCCCEEEECCCEECCCCCCCCCCHHHHHCCCCEEEEEHHH
ICDPRPGPPKRMLPGPELFASFMGELGLRDDAHLVAYDVHGLYSAARIWWMLRIYGHERI
HCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCEE
SVLDGGLPAWTAAGGATESGEPKRLPPTQWPVRPRGGLVRDWRQILDNIDSRQETVVDVR
EEECCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHEEEECC
PAEMFNGDTSAIYPGVRSGHIPGSVNVSQRDLRFENGKFRSIQDMRAIIAAAGVDPDGPM
HHHHHCCCCCEECCCCCCCCCCCCCCCCHHHEEECCCCCCHHHHHHHHHHHCCCCCCCCE
VASCGSGVTACVLSLAMEIIRGEPIPVYDGSWEEWGSRPDLPVEIN
EECCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]