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The map label for this gene is nadA1 [H]

Identifier: 110634898

GI number: 110634898

Start: 2746176

End: 2747150

Strand: Reverse

Name: nadA1 [H]

Synonym: Meso_2557

Alternate gene names: 110634898

Gene position: 2747150-2746176 (Counterclockwise)

Preceding gene: 110634899

Following gene: 110634897

Centisome position: 62.26

GC content: 61.64

Gene sequence:

>975_bases
ATGCTCGATATCCCCCGCACCGACGCGCTTTACGATAAGGTGAAGCGAGTGATCCCGCCGATCGAATGGCCGGCTTTCGT
GGACGATATCGAGGCAATTCTCGCGCTGAAGCGCAGGCGCAACGCGGTCATACTGGCGCACAACTATCAAACGCCGGAGA
TCTTCCACTGCGTTGGCGACATCGTGGGCGACAGCCTGGCGCTCGCCCGCGAGGCGGTGAACACGGATGCCGATGTCATC
GTGCTTGCCGGCGTCCATTTCATGGCCGAGACGGCAAAACTGCTCAATCCGGAAAAAACGGTGCTGATCCCGGATATGGG
GGCAGGGTGCTCGCTGGCCGATTCCATCACGGCAGAAGATGTGCGCCTGATGCGCCAGCATTATCCGGGCGTTCCCGTGA
TCACTTACGTCAACACGTCGGCGGCGGTGAAGGCGGAATCCGACATCTGCTGCACTTCCGGCAATGCGCGCGCGGTGGTG
GAATCGCTTGGCGTGCCGCGTGTGATCATGATCCCGGACGAGTATCTGGCAAAGAACATTGCCGCTGAAACGGACGTGGA
GATCATCGCCTGGAAAGGGCATTGCGAGGTGCATGAACGCTTCACCGGGGCTGATATCCGCGAATTGCGGGAGGCCAATC
CCGGCGTGGTGGTGCTCGCGCATCCCGAGTGCCCGCCGGAAGTGGTCGCGGAATCGGATTTCTCCGGCTCCACGGCCGCC
ATGTCGGACTATGTGGGACGGGAAAAGCCGCATCGCGTCGTGCTGATGACGGAATGCTCCATGAGCGACAATGTCGCGGT
GGCTCATCCGGATGTCGAGTTCGTCCGCCCCTGCAATCTCTGCCCGCATATGAAGCGCATCACGCTTGCCAATATCCGCA
AGGCGTTGGAGGAGAACCAGCACGTGGTGACGGTCGATCCTGAGGTGGCCGAGCGCGCGCGGCGCGCCGTGGAGCGGATG
CTCGCTGTCAAATGA

Upstream 100 bases:

>100_bases
CGCAGGAACAAAATTACCGGTTATTCGGGCTTGACAAGACTTATGCTCAGCGCAAGCATATATATGATATGCTCAATCGG
AGCATAATTGGAGATTGTCC

Downstream 100 bases:

>100_bases
ACGGCTTTGATCTTCACGACCTCAGCGGCCGCCCGGTCATTATCGGCGCTGGCCTTGCTGGGCTCGCAACCGCGCTTCAT
CTTTCACCCATGCCTGTCGT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MLDIPRTDALYDKVKRVIPPIEWPAFVDDIEAILALKRRRNAVILAHNYQTPEIFHCVGDIVGDSLALAREAVNTDADVI
VLAGVHFMAETAKLLNPEKTVLIPDMGAGCSLADSITAEDVRLMRQHYPGVPVITYVNTSAAVKAESDICCTSGNARAVV
ESLGVPRVIMIPDEYLAKNIAAETDVEIIAWKGHCEVHERFTGADIRELREANPGVVVLAHPECPPEVVAESDFSGSTAA
MSDYVGREKPHRVVLMTECSMSDNVAVAHPDVEFVRPCNLCPHMKRITLANIRKALEENQHVVTVDPEVAERARRAVERM
LAVK

Sequences:

>Translated_324_residues
MLDIPRTDALYDKVKRVIPPIEWPAFVDDIEAILALKRRRNAVILAHNYQTPEIFHCVGDIVGDSLALAREAVNTDADVI
VLAGVHFMAETAKLLNPEKTVLIPDMGAGCSLADSITAEDVRLMRQHYPGVPVITYVNTSAAVKAESDICCTSGNARAVV
ESLGVPRVIMIPDEYLAKNIAAETDVEIIAWKGHCEVHERFTGADIRELREANPGVVVLAHPECPPEVVAESDFSGSTAA
MSDYVGREKPHRVVLMTECSMSDNVAVAHPDVEFVRPCNLCPHMKRITLANIRKALEENQHVVTVDPEVAERARRAVERM
LAVK
>Mature_324_residues
MLDIPRTDALYDKVKRVIPPIEWPAFVDDIEAILALKRRRNAVILAHNYQTPEIFHCVGDIVGDSLALAREAVNTDADVI
VLAGVHFMAETAKLLNPEKTVLIPDMGAGCSLADSITAEDVRLMRQHYPGVPVITYVNTSAAVKAESDICCTSGNARAVV
ESLGVPRVIMIPDEYLAKNIAAETDVEIIAWKGHCEVHERFTGADIRELREANPGVVVLAHPECPPEVVAESDFSGSTAA
MSDYVGREKPHRVVLMTECSMSDNVAVAHPDVEFVRPCNLCPHMKRITLANIRKALEENQHVVTVDPEVAERARRAVERM
LAVK

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=328, Percent_Identity=35.3658536585366, Blast_Score=170, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 35568; Mature: 35568

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDIPRTDALYDKVKRVIPPIEWPAFVDDIEAILALKRRRNAVILAHNYQTPEIFHCVGD
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
IVGDSLALAREAVNTDADVIVLAGVHFMAETAKLLNPEKTVLIPDMGAGCSLADSITAED
HHCCHHHHHHHHHCCCCCEEEEECHHHHHHHHHHCCCCCEEEECCCCCCCCCHHCCCHHH
VRLMRQHYPGVPVITYVNTSAAVKAESDICCTSGNARAVVESLGVPRVIMIPDEYLAKNI
HHHHHHHCCCCCEEEEECCCCEEECCCCEEEECCCHHHHHHHCCCCEEEECCHHHHHHHH
AAETDVEIIAWKGHCEVHERFTGADIRELREANPGVVVLAHPECPPEVVAESDFSGSTAA
CCCCCEEEEEECCCCHHHHHCCCCHHHHHHCCCCCEEEEECCCCCHHHHCCCCCCCCHHH
MSDYVGREKPHRVVLMTECSMSDNVAVAHPDVEFVRPCNLCPHMKRITLANIRKALEENQ
HHHHHCCCCCCEEEEEEECCCCCCEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
HVVTVDPEVAERARRAVERMLAVK
EEEEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDIPRTDALYDKVKRVIPPIEWPAFVDDIEAILALKRRRNAVILAHNYQTPEIFHCVGD
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
IVGDSLALAREAVNTDADVIVLAGVHFMAETAKLLNPEKTVLIPDMGAGCSLADSITAED
HHCCHHHHHHHHHCCCCCEEEEECHHHHHHHHHHCCCCCEEEECCCCCCCCCHHCCCHHH
VRLMRQHYPGVPVITYVNTSAAVKAESDICCTSGNARAVVESLGVPRVIMIPDEYLAKNI
HHHHHHHCCCCCEEEEECCCCEEECCCCEEEECCCHHHHHHHCCCCEEEECCHHHHHHHH
AAETDVEIIAWKGHCEVHERFTGADIRELREANPGVVVLAHPECPPEVVAESDFSGSTAA
CCCCCEEEEEECCCCHHHHHCCCCHHHHHHCCCCCEEEEECCCCCHHHHCCCCCCCCHHH
MSDYVGREKPHRVVLMTECSMSDNVAVAHPDVEFVRPCNLCPHMKRITLANIRKALEENQ
HHHHHCCCCCCEEEEEEECCCCCCEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
HVVTVDPEVAERARRAVERMLAVK
EEEEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]