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The map label for this gene is mmgC [H]

Identifier: 110634822

GI number: 110634822

Start: 2658870

End: 2660090

Strand: Reverse

Name: mmgC [H]

Synonym: Meso_2481

Alternate gene names: 110634822

Gene position: 2660090-2658870 (Counterclockwise)

Preceding gene: 110634826

Following gene: 110634821

Centisome position: 60.29

GC content: 59.79

Gene sequence:

>1221_bases
ATGTCCAACACTTCGCATCAGGCCCCCCGCAACGAGGCGGAACGCGTCAGTTTTGCTTGGGACGACCCATTCCTGCTCGA
GGACCAGCTTACGGAAGAAGAGCGGATGATCCGCGATGCCGCGGCAGCTTTTGCCGCCGATCGTCTCCGTACGCGCGTCG
AGCATGCCTATATGAATGAGGAGACCGATCCGGCCATTTTCCGCGAGATGGGCGAGGCGGGTTTGCTTGGGGTCACCATT
CCCGAGGAGTATGGCGGGGCAGGGGCCAACTACGTGTCCTATGGTCTCGTCGCCCGCGAGGTGGAGCGGGTGGATTCGGG
CTACCGCTCGATGATGAGCGTGCAGTCCTCGCTGGTCATGTTTCCAATCTACGCCTATGGCTCCGAGGATCAGCGGAAGA
AATATCTGCCGAAGCTCGCCTCGGGTGAGTTCATCGGATGCTTTGGGCTCACGGAGCCTGATGCGGGCTCCGATCCCGGT
TCGATGAAAACGAGAGCGGAGAAGATAGACGGCGGCTATAGGCTCGTCGGCTCCAAGATGTGGATCTCGAACGCGCCGAT
CGCCGATGTCTTCGTGGTCTGGGCCAAGTCGGCCGCTCACGACAACCAGATACGCGGTTTTGTTCTCGAAAAGGGGATGA
AGGGCCTTTCGGCGCCCAAGATCGGCGGAAAGCTTTCATTGCGTGCTTCCATCACCGGAGAGGTCGTGATGGATGGCGTG
GAAGTGCCGGAGGATGCCCTTCTTCCTAATGTCTCGGGACTTAAGGGGCCATTCGGCTGCCTGAACCGCGCCCGCTACGG
CATTTCCTGGGGCGTGATGGGAGCGGCTGAAGATTGTTGGCACCGCGCCCGCCAATATGGGTTGGAGCGCCAGCAGTTTG
GCCGGCCGTTGGCGGCGACGCAGCTATTCCAAAAGAAGCTGGCCGACATGCAGACGGAAATCGCGCTCGGGCTGCAGGCG
AGCTTGCGTGTCGGGCGGCTTATGGACGAGCATAAATTTGCGCCGGAGATGATTTCGATCGTGAAGCGCAACAATTGCGG
CAAGGCGCTTGATATTGCCCGAATGGCGCGTGACATGCATGGGGGCAACGGCATTCAGATCGAGTATCAGGTGATGCGGC
ATTCGCAGAACCTGGAGACGGTGAACACCTATGAGGGTACGCATGACGTGCATGCCCTTATCCTGGGTCGAGCGCAGACC
GGTTTGCAGGCCTTTTTCTGA

Upstream 100 bases:

>100_bases
TATGCATCAACTTACGCTCAAATAGGATTTTTCCGGCCCGTATGCTACAGGTAAACGCATCTGCAGGTGATCCTTCACGC
GATCTAACCGAGGAGCAGGA

Downstream 100 bases:

>100_bases
TCAGCTCAGGCACGCTGCTCGCGAAAACCTTCAGAACAGGGCGAATACTAATTTTGCAGAGCGCAGCCGAAGAAGCTGCG
CTCTGTTCGATGATCGAGTA

Product: acyl-CoA dehydrogenase-like

Products: crotonoyl-CoA; CO2; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSNTSHQAPRNEAERVSFAWDDPFLLEDQLTEEERMIRDAAAAFAADRLRTRVEHAYMNEETDPAIFREMGEAGLLGVTI
PEEYGGAGANYVSYGLVAREVERVDSGYRSMMSVQSSLVMFPIYAYGSEDQRKKYLPKLASGEFIGCFGLTEPDAGSDPG
SMKTRAEKIDGGYRLVGSKMWISNAPIADVFVVWAKSAAHDNQIRGFVLEKGMKGLSAPKIGGKLSLRASITGEVVMDGV
EVPEDALLPNVSGLKGPFGCLNRARYGISWGVMGAAEDCWHRARQYGLERQQFGRPLAATQLFQKKLADMQTEIALGLQA
SLRVGRLMDEHKFAPEMISIVKRNNCGKALDIARMARDMHGGNGIQIEYQVMRHSQNLETVNTYEGTHDVHALILGRAQT
GLQAFF

Sequences:

>Translated_406_residues
MSNTSHQAPRNEAERVSFAWDDPFLLEDQLTEEERMIRDAAAAFAADRLRTRVEHAYMNEETDPAIFREMGEAGLLGVTI
PEEYGGAGANYVSYGLVAREVERVDSGYRSMMSVQSSLVMFPIYAYGSEDQRKKYLPKLASGEFIGCFGLTEPDAGSDPG
SMKTRAEKIDGGYRLVGSKMWISNAPIADVFVVWAKSAAHDNQIRGFVLEKGMKGLSAPKIGGKLSLRASITGEVVMDGV
EVPEDALLPNVSGLKGPFGCLNRARYGISWGVMGAAEDCWHRARQYGLERQQFGRPLAATQLFQKKLADMQTEIALGLQA
SLRVGRLMDEHKFAPEMISIVKRNNCGKALDIARMARDMHGGNGIQIEYQVMRHSQNLETVNTYEGTHDVHALILGRAQT
GLQAFF
>Mature_405_residues
SNTSHQAPRNEAERVSFAWDDPFLLEDQLTEEERMIRDAAAAFAADRLRTRVEHAYMNEETDPAIFREMGEAGLLGVTIP
EEYGGAGANYVSYGLVAREVERVDSGYRSMMSVQSSLVMFPIYAYGSEDQRKKYLPKLASGEFIGCFGLTEPDAGSDPGS
MKTRAEKIDGGYRLVGSKMWISNAPIADVFVVWAKSAAHDNQIRGFVLEKGMKGLSAPKIGGKLSLRASITGEVVMDGVE
VPEDALLPNVSGLKGPFGCLNRARYGISWGVMGAAEDCWHRARQYGLERQQFGRPLAATQLFQKKLADMQTEIALGLQAS
LRVGRLMDEHKFAPEMISIVKRNNCGKALDIARMARDMHGGNGIQIEYQVMRHSQNLETVNTYEGTHDVHALILGRAQTG
LQAFF

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4503943, Length=401, Percent_Identity=64.3391521197007, Blast_Score=525, Evalue=1e-149,
Organism=Homo sapiens, GI7669494, Length=381, Percent_Identity=63.254593175853, Blast_Score=489, Evalue=1e-138,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=31.6489361702128, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI226958414, Length=346, Percent_Identity=32.3699421965318, Blast_Score=175, Evalue=9e-44,
Organism=Homo sapiens, GI4501859, Length=365, Percent_Identity=31.5068493150685, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI4557233, Length=371, Percent_Identity=30.9973045822102, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI76496475, Length=350, Percent_Identity=33.1428571428571, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI4557235, Length=350, Percent_Identity=33.1428571428571, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI21361497, Length=348, Percent_Identity=30.1724137931034, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI4557231, Length=375, Percent_Identity=28.5333333333333, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI187960098, Length=375, Percent_Identity=28.5333333333333, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI4501857, Length=344, Percent_Identity=29.6511627906977, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI7656849, Length=379, Percent_Identity=28.4960422163588, Blast_Score=132, Evalue=5e-31,
Organism=Escherichia coli, GI1786223, Length=334, Percent_Identity=24.5508982035928, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081958, Length=386, Percent_Identity=26.1658031088083, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87081702, Length=174, Percent_Identity=28.735632183908, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17534353, Length=391, Percent_Identity=64.7058823529412, Blast_Score=520, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI17538396, Length=375, Percent_Identity=34.6666666666667, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI17506239, Length=289, Percent_Identity=34.9480968858132, Blast_Score=164, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI17508101, Length=366, Percent_Identity=31.1475409836066, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71990804, Length=257, Percent_Identity=36.1867704280156, Blast_Score=157, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI71985184, Length=377, Percent_Identity=29.973474801061, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17569725, Length=378, Percent_Identity=29.6296296296296, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17534899, Length=376, Percent_Identity=28.1914893617021, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71985192, Length=280, Percent_Identity=32.5, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=36.3636363636364, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17570075, Length=379, Percent_Identity=27.9683377308707, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI71982178, Length=273, Percent_Identity=30.03663003663, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17533517, Length=368, Percent_Identity=24.7282608695652, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17551932, Length=249, Percent_Identity=26.1044176706827, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17505929, Length=249, Percent_Identity=24.4979919678715, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19920834, Length=392, Percent_Identity=60.969387755102, Blast_Score=469, Evalue=1e-132,
Organism=Drosophila melanogaster, GI24666513, Length=372, Percent_Identity=31.1827956989247, Blast_Score=188, Evalue=6e-48,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=30.5851063829787, Blast_Score=178, Evalue=7e-45,
Organism=Drosophila melanogaster, GI24646207, Length=374, Percent_Identity=31.0160427807487, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=30.1587301587302, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI281363737, Length=408, Percent_Identity=29.4117647058824, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI21355753, Length=337, Percent_Identity=30.2670623145401, Blast_Score=151, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.7

Molecular weight: Translated: 44797; Mature: 44665

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTSHQAPRNEAERVSFAWDDPFLLEDQLTEEERMIRDAAAAFAADRLRTRVEHAYMNE
CCCCCCCCCCCHHHEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ETDPAIFREMGEAGLLGVTIPEEYGGAGANYVSYGLVAREVERVDSGYRSMMSVQSSLVM
CCCHHHHHHCCCCCEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
FPIYAYGSEDQRKKYLPKLASGEFIGCFGLTEPDAGSDPGSMKTRAEKIDGGYRLVGSKM
EEEEECCCCHHHHHHCCHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHCCCCEEEEECEE
WISNAPIADVFVVWAKSAAHDNQIRGFVLEKGMKGLSAPKIGGKLSLRASITGEVVMDGV
EECCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHHCCCC
EVPEDALLPNVSGLKGPFGCLNRARYGISWGVMGAAEDCWHRARQYGLERQQFGRPLAAT
CCCHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCHHHH
QLFQKKLADMQTEIALGLQASLRVGRLMDEHKFAPEMISIVKRNNCGKALDIARMARDMH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHC
GGNGIQIEYQVMRHSQNLETVNTYEGTHDVHALILGRAQTGLQAFF
CCCCEEEEEHEECCCCCCCEEECCCCCHHHHHHEEHHHHHHHHHCC
>Mature Secondary Structure 
SNTSHQAPRNEAERVSFAWDDPFLLEDQLTEEERMIRDAAAAFAADRLRTRVEHAYMNE
CCCCCCCCCCHHHEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ETDPAIFREMGEAGLLGVTIPEEYGGAGANYVSYGLVAREVERVDSGYRSMMSVQSSLVM
CCCHHHHHHCCCCCEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
FPIYAYGSEDQRKKYLPKLASGEFIGCFGLTEPDAGSDPGSMKTRAEKIDGGYRLVGSKM
EEEEECCCCHHHHHHCCHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHCCCCEEEEECEE
WISNAPIADVFVVWAKSAAHDNQIRGFVLEKGMKGLSAPKIGGKLSLRASITGEVVMDGV
EECCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCHHHCCCC
EVPEDALLPNVSGLKGPFGCLNRARYGISWGVMGAAEDCWHRARQYGLERQQFGRPLAAT
CCCHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCHHHH
QLFQKKLADMQTEIALGLQASLRVGRLMDEHKFAPEMISIVKRNNCGKALDIARMARDMH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHC
GGNGIQIEYQVMRHSQNLETVNTYEGTHDVHALILGRAQTGLQAFF
CCCCEEEEEHEECCCCCCCEEECCCCCHHHHHHEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutaryl-CoA; acceptor

Specific reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]