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The map label for this gene is cyoC [H]

Identifier: 110634818

GI number: 110634818

Start: 2656018

End: 2656740

Strand: Direct

Name: cyoC [H]

Synonym: Meso_2477

Alternate gene names: 110634818

Gene position: 2656018-2656740 (Clockwise)

Preceding gene: 110634817

Following gene: 110634819

Centisome position: 60.19

GC content: 60.03

Gene sequence:

>723_bases
ATGGCTGAGACCACGCTGAACGGCTTCGAAGCCAAGGAGGCGCACCAGAACGGCCTCAGGGGCGTGGCCGCCGACTGGTC
GTCCGACCAGCGCGCTTTCAAAAGCGCATCCTGGGGGAAGGCCATGATGTGGATCTTCCTCCTGTCCGATACCTTCGTCT
TCTCTTGTTTCCTGCTCGCCTACATGACGGTGCGCATGTCCACCGTCGAACCCTGGCCGAACGCCAGCGAGGTCTTCGCC
CTCCATATTGCCGGCGCTGACATCCCCCTCATCCTGATCGCCATCATGACCTTCGTGCTCATCTCCTCGAGCGGCACCAT
GGCAATGGCCGTGAATTTTGCTTACCGGCGCAACAGAAGCGCGACCGTGGCGCTGCTTCTTGCGACAGCGCTGCTTGGCG
CGGCCTTCGTCGGCATGCAGGCTTTCGAATGGACGAAGCTCATTACCGAGGGCGTGCGCCCGTGGGGCAACCCGTGGGGA
GCACCGCAATTCGGCGCTACCTTTTTCATGATCACCGGCTTTCACGGAACCCACGTCACGTTCGGCGTCATATTCCTCTT
GATCGTGGCGTTCAAAGTATGGCGCGGCGAGTACGACCGGGGTGAACGCGGCTTTTTCACCACCCGCCGCGGCGATTATG
AGCACGTGGAGATCATGGGCCTCTACTGGCACTTCGTCGATCTCGTCTGGGTATTCATTTTCGCATTCTTCTATCTCTGG
TGA

Upstream 100 bases:

>100_bases
TCTTTTGCTTATCTGGCTCGGACTTTTCGTCCTGCTGGCCGGTTGGGCTGGCGATCTCGTCGCATTGTGCAGACAGTTGC
TCACATGAAGGGGACAAGAA

Downstream 100 bases:

>100_bases
GGAACGGCTATGGCAACGCATACGGAGCAGACCGGTCACGGATATTCGCAGACCGCCATCGCCGCCCACGCAGAGAGCCA
GCAGCACCCGATCAGGATTT

Product: cytochrome c oxidase, subunit III

Products: ferricytochrome c; H2O

Alternate protein names: Cytochrome o ubiquinol oxidase subunit III; Ubiquinol oxidase chain C [H]

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MAETTLNGFEAKEAHQNGLRGVAADWSSDQRAFKSASWGKAMMWIFLLSDTFVFSCFLLAYMTVRMSTVEPWPNASEVFA
LHIAGADIPLILIAIMTFVLISSSGTMAMAVNFAYRRNRSATVALLLATALLGAAFVGMQAFEWTKLITEGVRPWGNPWG
APQFGATFFMITGFHGTHVTFGVIFLLIVAFKVWRGEYDRGERGFFTTRRGDYEHVEIMGLYWHFVDLVWVFIFAFFYLW

Sequences:

>Translated_240_residues
MAETTLNGFEAKEAHQNGLRGVAADWSSDQRAFKSASWGKAMMWIFLLSDTFVFSCFLLAYMTVRMSTVEPWPNASEVFA
LHIAGADIPLILIAIMTFVLISSSGTMAMAVNFAYRRNRSATVALLLATALLGAAFVGMQAFEWTKLITEGVRPWGNPWG
APQFGATFFMITGFHGTHVTFGVIFLLIVAFKVWRGEYDRGERGFFTTRRGDYEHVEIMGLYWHFVDLVWVFIFAFFYLW
>Mature_239_residues
AETTLNGFEAKEAHQNGLRGVAADWSSDQRAFKSASWGKAMMWIFLLSDTFVFSCFLLAYMTVRMSTVEPWPNASEVFAL
HIAGADIPLILIAIMTFVLISSSGTMAMAVNFAYRRNRSATVALLLATALLGAAFVGMQAFEWTKLITEGVRPWGNPWGA
PQFGATFFMITGFHGTHVTFGVIFLLIVAFKVWRGEYDRGERGFFTTRRGDYEHVEIMGLYWHFVDLVWVFIFAFFYLW

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration [H]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=155, Percent_Identity=33.5483870967742, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI1786633, Length=196, Percent_Identity=32.6530612244898, Blast_Score=98, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833
- InterPro:   IPR014206 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: 1.9.3.1

Molecular weight: Translated: 27142; Mature: 27011

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETTLNGFEAKEAHQNGLRGVAADWSSDQRAFKSASWGKAMMWIFLLSDTFVFSCFLLA
CCCCCCCCCHHHHHHHCCCCCEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
YMTVRMSTVEPWPNASEVFALHIAGADIPLILIAIMTFVLISSSGTMAMAVNFAYRRNRS
HHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCC
ATVALLLATALLGAAFVGMQAFEWTKLITEGVRPWGNPWGAPQFGATFFMITGFHGTHVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHH
FGVIFLLIVAFKVWRGEYDRGERGFFTTRRGDYEHVEIMGLYWHFVDLVWVFIFAFFYLW
HHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
AETTLNGFEAKEAHQNGLRGVAADWSSDQRAFKSASWGKAMMWIFLLSDTFVFSCFLLA
CCCCCCCCHHHHHHHCCCCCEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
YMTVRMSTVEPWPNASEVFALHIAGADIPLILIAIMTFVLISSSGTMAMAVNFAYRRNRS
HHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCC
ATVALLLATALLGAAFVGMQAFEWTKLITEGVRPWGNPWGAPQFGATFFMITGFHGTHVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHH
FGVIFLLIVAFKVWRGEYDRGERGFFTTRRGDYEHVEIMGLYWHFVDLVWVFIFAFFYLW
HHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ferrocytochrome c; O2

Specific reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]