Click here to switch to the map view.

The map label for this gene is aiiA [H]

Identifier: 110634747

GI number: 110634747

Start: 2563501

End: 2564214

Strand: Reverse

Name: aiiA [H]

Synonym: Meso_2405

Alternate gene names: 110634747

Gene position: 2564214-2563501 (Counterclockwise)

Preceding gene: 110634748

Following gene: 110634746

Centisome position: 58.11

GC content: 63.87

Gene sequence:

>714_bases
ATGACCGAGGCCAGCTATGAGATACTCATGCCGGGCTTTCCTGGGCGCAGCTCCCGCGGTTTCCTCGGCTGGAGCACGAT
CCTGCTGCTGAAAACCGCCCGCGGGCTGGCGCTGTTCGACACAGGCGCCAGCGGCGACCGCCCCGGGCTGATGGCGGCGC
TGCGCGGGCGCGGCATCGAGCCGGACCGGATCGGGACGGTCATCCTTTCGCATCTGCATTTCGATCATATGGCCAATGCC
GAATGCTTCCCGAAGGCGGAGATCATCCTGCACGAGGACGAATATGCCTATGTGCGCGAACATGGCGCGGCGGACCCGGC
CATATCGGTCTTCCAGGTCGATGGGTTGCTGCGAAGCGCGCAGCTGAGCCTTGTTGCCGGCGAGATCGAGGTCCTGCCGG
GTGTGCGGATGATCAGGACACCTGGCCATAGCGGCGGTCATGTCTCTCTGGTGCTGACGGTCGAAAATCGCCGCGTGGTG
CTGGCGCAGGACGCAATCAAGCATCGCGGCGAACTGGTCTCCCGCCATTCGGCGGGCTCCTTCGACGAAGCGGCAGCCAA
TGCCAGTATACGGCGCATTGCTGGAATGGCCGACGTGATCGTACCGGGTCACGACGGTCCCATCACCGTTGAAAATGGCG
AATACATCGCCTCCGGCGTCTCTGCCGAGATTTCGCTCACCTTGCGCGAGAAGCGCTTTCCGCTGGAGGCCTGA

Upstream 100 bases:

>100_bases
CCGGGCGTCGCCATCTTCGTCACCGTAATGGGCACCAATCTGGTCGGCGACCGGTTGCGCGACCTGCTCGATCCGCGGTT
GCGCCAGGTGGAATCCTGAC

Downstream 100 bases:

>100_bases
GATGGCGACGCTGCTCCATAATGCCTTCATCTGCACCGGCCGCCCCGACGGTTTCTTCCAGGATGGCGCTATTCTGATCC
GCGACGGCAGGGTCGACTGG

Product: beta-lactamase-like

Products: NA

Alternate protein names: AHL-lactonase AiiA [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTEASYEILMPGFPGRSSRGFLGWSTILLLKTARGLALFDTGASGDRPGLMAALRGRGIEPDRIGTVILSHLHFDHMANA
ECFPKAEIILHEDEYAYVREHGAADPAISVFQVDGLLRSAQLSLVAGEIEVLPGVRMIRTPGHSGGHVSLVLTVENRRVV
LAQDAIKHRGELVSRHSAGSFDEAAANASIRRIAGMADVIVPGHDGPITVENGEYIASGVSAEISLTLREKRFPLEA

Sequences:

>Translated_237_residues
MTEASYEILMPGFPGRSSRGFLGWSTILLLKTARGLALFDTGASGDRPGLMAALRGRGIEPDRIGTVILSHLHFDHMANA
ECFPKAEIILHEDEYAYVREHGAADPAISVFQVDGLLRSAQLSLVAGEIEVLPGVRMIRTPGHSGGHVSLVLTVENRRVV
LAQDAIKHRGELVSRHSAGSFDEAAANASIRRIAGMADVIVPGHDGPITVENGEYIASGVSAEISLTLREKRFPLEA
>Mature_236_residues
TEASYEILMPGFPGRSSRGFLGWSTILLLKTARGLALFDTGASGDRPGLMAALRGRGIEPDRIGTVILSHLHFDHMANAE
CFPKAEIILHEDEYAYVREHGAADPAISVFQVDGLLRSAQLSLVAGEIEVLPGVRMIRTPGHSGGHVSLVLTVENRRVVL
AQDAIKHRGELVSRHSAGSFDEAAANASIRRIAGMADVIVPGHDGPITVENGEYIASGVSAEISLTLREKRFPLEA

Specific function: Catalyzes hydrolysis of N-hexanoyl-(S)-homoserine lactone, but not the R-enantiomer. Hydrolyzes short- and long- chain N-acyl homoserine lactones with or without 3-oxo substitution at C3, has maximum activity on C10-AHL [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.1.81 [H]

Molecular weight: Translated: 25423; Mature: 25292

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEASYEILMPGFPGRSSRGFLGWSTILLLKTARGLALFDTGASGDRPGLMAALRGRGIE
CCCCCEEEEECCCCCCCCCCCCHHHHEEEEHHCCCEEEEECCCCCCCCCHHHHHHCCCCC
PDRIGTVILSHLHFDHMANAECFPKAEIILHEDEYAYVREHGAADPAISVFQVDGLLRSA
CHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHCCCCCCCEEEEEECCHHHHH
QLSLVAGEIEVLPGVRMIRTPGHSGGHVSLVLTVENRRVVLAQDAIKHRGELVSRHSAGS
EEEEEECEEEECCCEEEEECCCCCCCEEEEEEEECCCEEEEEHHHHHHHHHHHHCCCCCC
FDEAAANASIRRIAGMADVIVPGHDGPITVENGEYIASGVSAEISLTLREKRFPLEA
CHHHHHCCHHHHHCCCEEEEEECCCCCEEEECCCEEECCCCEEEEEEEECCCCCCCC
>Mature Secondary Structure 
TEASYEILMPGFPGRSSRGFLGWSTILLLKTARGLALFDTGASGDRPGLMAALRGRGIE
CCCCEEEEECCCCCCCCCCCCHHHHEEEEHHCCCEEEEECCCCCCCCCHHHHHHCCCCC
PDRIGTVILSHLHFDHMANAECFPKAEIILHEDEYAYVREHGAADPAISVFQVDGLLRSA
CHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHCCCCCCCEEEEEECCHHHHH
QLSLVAGEIEVLPGVRMIRTPGHSGGHVSLVLTVENRRVVLAQDAIKHRGELVSRHSAGS
EEEEEECEEEECCCEEEEECCCCCCCEEEEEEEECCCEEEEEHHHHHHHHHHHHCCCCCC
FDEAAANASIRRIAGMADVIVPGHDGPITVENGEYIASGVSAEISLTLREKRFPLEA
CHHHHHCCHHHHHCCCEEEEEECCCCCEEEECCCEEECCCCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11916693; 12147491 [H]