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The map label for this gene is gsiB [H]

Identifier: 110634718

GI number: 110634718

Start: 2528875

End: 2530419

Strand: Direct

Name: gsiB [H]

Synonym: Meso_2375

Alternate gene names: 110634718

Gene position: 2528875-2530419 (Clockwise)

Preceding gene: 110634710

Following gene: 110634720

Centisome position: 57.31

GC content: 58.25

Gene sequence:

>1545_bases
ATGGTGAATCGCCGGCAACTGATGTTTGGGGCCGCAGCCATGGGATTAACCGGCTCGCTCGCATTTCGGGCTTACGCTCA
GAGTGCAGCGGCAGGCGAAGGCACACTTACTTTCGGAACGCTTGGTCTTCTCGCCGGGCTTGATCCGCATGTTGCCGCCA
GCTCGGTGTGGCGCAAGACCACGACGATGATTTACGATCGGCTGCTCGGCTACGACACGACTGGAAAGTTGCAGGGCGAG
CTCGCCGAAAGCTGGGAGTTCAGCGATCCGACCACCTTCGTCGTCAAGCTGAAACCGGGCGTGACCTTCCACAAGGGGCA
GCGGTTCAGTGCCGCAGACGTCGTTTACACGTTCTCGCGTATACAGGATCCTGCGGTGGGTGCGACGTTAGCAAAGCCGC
TGGAGGGCGTCGAAGTGGAATCGCGTGATGACGCGACCGTTGTCTTCAAGCTGCCGCAACCCGACGTGAGTTTTCCAAGC
CTGCTCGCCTCGGAAGAGGTGGCGATCGTTTCAGCCGAATGGATGGCCGGTTCGCCGAACGTCTCGGTTGAAGCGAACGG
AACCGGTCCATTCATGCTCGAAAGCTTCGATCCGAAAGTCCAGACGGTGGTCAAGCGCAATCCCGACTTCTATGATGGTC
CGGCCAAGCTGGAAAGCATCATCTTCCGCTCGATCGCCGACGACAGCGCTCGAATAAACGCGCTCAAGACCGGCAGTGTG
GATCTGATCGACACAGTCCCATGGAATCAGATCGATGGTTTGAAGAATGCGCCCGGATTAACTGTGTTCTCGGCGCCGGC
AGCATTCATGAGCCTTTGGTGCAACGTCTCTCGTCCGGTAATGGCCGACCCGAGAGTCCGTCGCGCAATCGCCTATGCGA
TCGACCGCAACGCAGTGTCGACGGCAGCCTTTTTTGGCTACGGCGCGCCATTGGGCGGGCTTCCCATGCCGGAGACGTCG
CCTTTTCATAATCCGGAATCGGCAGAAATCTTCAACTACGATCCGGAAAAGGCACGTGCTCTGTTGAAGGAAGCCGGCGC
GGAAGGACTGGAGATCGAATTCCTCGTCTCTCAGGCTCCGGCAGTCTATGTGGTGGTGGGGCAGATCGTCGCCGCGAATC
TGGCTGCGGTGGGCATCAAGGCGAATATCCAGTTGGTTGATTTCCCCACCGTGGTCGAGCGGAAGAACTCTGGCAACTAC
GATCTCGTTATCTATGGCACGAACATCCGCGGCCCAGACCCGAACCTTGCCTATTCCTATTTCTTCGAGCCTGGTACCGG
CTTCTGGGCTAACGGCGCCAAGTTCCAGGACCCCAAGGTGAGTGATCTCCTGGCGAGGGGCCGGTCCGAACTCGACTCCG
AGAAGCGGAAGGAAGTCTACAAGGAGCTCGAACTTTACCTGCTGGAGATCAGCCCTTGGATCTTCATCACCTGGCGCGAC
GACGCCATGGCATACAAATCATCGCTGCAGGGAATGGCACATCTCGAGGGAGCTCTGAACGTCGTCAGCGTTTCCATTTC
CGCACCGCACCTATTCTGGTCATAA

Upstream 100 bases:

>100_bases
ATTGACCTCTCGATCGCGCCCTTGACAACAGCACCACTCATCCATTAATAGAAACACTGTAACGATAATAGCAACAATAT
GCCAGGTAGGGGACTTTCAA

Downstream 100 bases:

>100_bases
TGACCCCGACAGGGCCGGACGCATTGTGCGTCCGGTTCCTTTGGCGAGAGTGACCATGACTGCATCTGAAACAGTTCTCC
AGGTCAAGAACCTGAGCATG

Product: twin-arginine translocation pathway signal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MVNRRQLMFGAAAMGLTGSLAFRAYAQSAAAGEGTLTFGTLGLLAGLDPHVAASSVWRKTTTMIYDRLLGYDTTGKLQGE
LAESWEFSDPTTFVVKLKPGVTFHKGQRFSAADVVYTFSRIQDPAVGATLAKPLEGVEVESRDDATVVFKLPQPDVSFPS
LLASEEVAIVSAEWMAGSPNVSVEANGTGPFMLESFDPKVQTVVKRNPDFYDGPAKLESIIFRSIADDSARINALKTGSV
DLIDTVPWNQIDGLKNAPGLTVFSAPAAFMSLWCNVSRPVMADPRVRRAIAYAIDRNAVSTAAFFGYGAPLGGLPMPETS
PFHNPESAEIFNYDPEKARALLKEAGAEGLEIEFLVSQAPAVYVVVGQIVAANLAAVGIKANIQLVDFPTVVERKNSGNY
DLVIYGTNIRGPDPNLAYSYFFEPGTGFWANGAKFQDPKVSDLLARGRSELDSEKRKEVYKELELYLLEISPWIFITWRD
DAMAYKSSLQGMAHLEGALNVVSVSISAPHLFWS

Sequences:

>Translated_514_residues
MVNRRQLMFGAAAMGLTGSLAFRAYAQSAAAGEGTLTFGTLGLLAGLDPHVAASSVWRKTTTMIYDRLLGYDTTGKLQGE
LAESWEFSDPTTFVVKLKPGVTFHKGQRFSAADVVYTFSRIQDPAVGATLAKPLEGVEVESRDDATVVFKLPQPDVSFPS
LLASEEVAIVSAEWMAGSPNVSVEANGTGPFMLESFDPKVQTVVKRNPDFYDGPAKLESIIFRSIADDSARINALKTGSV
DLIDTVPWNQIDGLKNAPGLTVFSAPAAFMSLWCNVSRPVMADPRVRRAIAYAIDRNAVSTAAFFGYGAPLGGLPMPETS
PFHNPESAEIFNYDPEKARALLKEAGAEGLEIEFLVSQAPAVYVVVGQIVAANLAAVGIKANIQLVDFPTVVERKNSGNY
DLVIYGTNIRGPDPNLAYSYFFEPGTGFWANGAKFQDPKVSDLLARGRSELDSEKRKEVYKELELYLLEISPWIFITWRD
DAMAYKSSLQGMAHLEGALNVVSVSISAPHLFWS
>Mature_514_residues
MVNRRQLMFGAAAMGLTGSLAFRAYAQSAAAGEGTLTFGTLGLLAGLDPHVAASSVWRKTTTMIYDRLLGYDTTGKLQGE
LAESWEFSDPTTFVVKLKPGVTFHKGQRFSAADVVYTFSRIQDPAVGATLAKPLEGVEVESRDDATVVFKLPQPDVSFPS
LLASEEVAIVSAEWMAGSPNVSVEANGTGPFMLESFDPKVQTVVKRNPDFYDGPAKLESIIFRSIADDSARINALKTGSV
DLIDTVPWNQIDGLKNAPGLTVFSAPAAFMSLWCNVSRPVMADPRVRRAIAYAIDRNAVSTAAFFGYGAPLGGLPMPETS
PFHNPESAEIFNYDPEKARALLKEAGAEGLEIEFLVSQAPAVYVVVGQIVAANLAAVGIKANIQLVDFPTVVERKNSGNY
DLVIYGTNIRGPDPNLAYSYFFEPGTGFWANGAKFQDPKVSDLLARGRSELDSEKRKEVYKELELYLLEISPWIFITWRD
DAMAYKSSLQGMAHLEGALNVVSVSISAPHLFWS

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787052, Length=506, Percent_Identity=29.2490118577075, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1789966, Length=496, Percent_Identity=26.8145161290323, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1787762, Length=519, Percent_Identity=24.2774566473988, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1787551, Length=494, Percent_Identity=26.3157894736842, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1789887, Length=448, Percent_Identity=22.3214285714286, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787495, Length=512, Percent_Identity=22.4609375, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789397, Length=463, Percent_Identity=21.5982721382289, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87081878, Length=466, Percent_Identity=22.5321888412017, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 55750; Mature: 55750

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNRRQLMFGAAAMGLTGSLAFRAYAQSAAAGEGTLTFGTLGLLAGLDPHVAASSVWRKT
CCCCCEEEHHHHHHCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHH
TTMIYDRLLGYDTTGKLQGELAESWEFSDPTTFVVKLKPGVTFHKGQRFSAADVVYTFSR
HHHHHHHHHCCCCCCCCCCHHHHCCCCCCCEEEEEEECCCCEEECCCCCCHHHHHHHHHH
IQDPAVGATLAKPLEGVEVESRDDATVVFKLPQPDVSFPSLLASEEVAIVSAEWMAGSPN
CCCCCCCHHHHCCCCCCEECCCCCCEEEEECCCCCCCCHHHHCCCCEEEEEEEEECCCCC
VSVEANGTGPFMLESFDPKVQTVVKRNPDFYDGPAKLESIIFRSIADDSARINALKTGSV
EEEEECCCCCEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCE
DLIDTVPWNQIDGLKNAPGLTVFSAPAAFMSLWCNVSRPVMADPRVRRAIAYAIDRNAVS
EEEECCCCHHCCCCCCCCCEEEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHH
TAAFFGYGAPLGGLPMPETSPFHNPESAEIFNYDPEKARALLKEAGAEGLEIEFLVSQAP
HHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCEEEEEECCCC
AVYVVVGQIVAANLAAVGIKANIQLVDFPTVVERKNSGNYDLVIYGTNIRGPDPNLAYSY
EEEEEHHHHHHHHHHEEEEEEEEEEEECCHHHCCCCCCCEEEEEEECCCCCCCCCCEEEE
FFEPGTGFWANGAKFQDPKVSDLLARGRSELDSEKRKEVYKELELYLLEISPWIFITWRD
EECCCCCCCCCCCCCCCCCHHHHHHCCHHHCCHHHHHHHHHHHEEEEEEECCEEEEEECC
DAMAYKSSLQGMAHLEGALNVVSVSISAPHLFWS
HHHHHHHHHCHHHHHCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure
MVNRRQLMFGAAAMGLTGSLAFRAYAQSAAAGEGTLTFGTLGLLAGLDPHVAASSVWRKT
CCCCCEEEHHHHHHCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHH
TTMIYDRLLGYDTTGKLQGELAESWEFSDPTTFVVKLKPGVTFHKGQRFSAADVVYTFSR
HHHHHHHHHCCCCCCCCCCHHHHCCCCCCCEEEEEEECCCCEEECCCCCCHHHHHHHHHH
IQDPAVGATLAKPLEGVEVESRDDATVVFKLPQPDVSFPSLLASEEVAIVSAEWMAGSPN
CCCCCCCHHHHCCCCCCEECCCCCCEEEEECCCCCCCCHHHHCCCCEEEEEEEEECCCCC
VSVEANGTGPFMLESFDPKVQTVVKRNPDFYDGPAKLESIIFRSIADDSARINALKTGSV
EEEEECCCCCEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCE
DLIDTVPWNQIDGLKNAPGLTVFSAPAAFMSLWCNVSRPVMADPRVRRAIAYAIDRNAVS
EEEECCCCHHCCCCCCCCCEEEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHH
TAAFFGYGAPLGGLPMPETSPFHNPESAEIFNYDPEKARALLKEAGAEGLEIEFLVSQAP
HHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCEEEEEECCCC
AVYVVVGQIVAANLAAVGIKANIQLVDFPTVVERKNSGNYDLVIYGTNIRGPDPNLAYSY
EEEEEHHHHHHHHHHEEEEEEEEEEEECCHHHCCCCCCCEEEEEEECCCCCCCCCCEEEE
FFEPGTGFWANGAKFQDPKVSDLLARGRSELDSEKRKEVYKELELYLLEISPWIFITWRD
EECCCCCCCCCCCCCCCCCHHHHHHCCHHHCCHHHHHHHHHHHEEEEEEECCEEEEEECC
DAMAYKSSLQGMAHLEGALNVVSVSISAPHLFWS
HHHHHHHHHCHHHHHCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA