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The map label for this gene is rutB [H]

Identifier: 110634651

GI number: 110634651

Start: 2461553

End: 2462293

Strand: Direct

Name: rutB [H]

Synonym: Meso_2306

Alternate gene names: 110634651

Gene position: 2461553-2462293 (Clockwise)

Preceding gene: 110634645

Following gene: 110634653

Centisome position: 55.79

GC content: 56.82

Gene sequence:

>741_bases
ATGCAATTCTCAGCGATTCCGCAACACATCGTAGATCGGGTAGTCGACAGGCGCGGCGCCTTGCACATCCACCAGAACAT
CGACCCGACGAAAACGGCCCTCGTTGTCATCGATCTACAGAACTGTTTTATGGTCGAGGAGCTAGCGTTCGCCTATTCAT
GCGGGGCGATAAAGCTCGTTCCGATCGTGAACCGCGTTGCAGACGAGGTTCGGCGAGCAGGCGGCAAGGTCTTCTGGATC
AGAAACACCATCAGTGAGGACATGCGCGAAAACTGGTCGAACTGGTTCGCAATGAACGGGTACGACCCCGAACGCGCGGC
TCGGCGCGAAGTCAACATGATCGTTGGCTCACCCGGCCATCAGATCCACTCGGATCTCGTGATCGCACCCCAGGATGAGA
TCGTCGACAAGCATCGTTTCAGTGCATTCATCCAGGGATCGTCCGATATAGATGACAGGCTTCGGGCTCAGGGTATCGAC
ACGCTCATTTTCGCGGGCATCGCTACCAACGTCTGCTGCGAATCGTCGGCGCGTGACGCGATGATGTTGAACTACAAAGT
CATTGTGGTCACCGATGCGACCGCAGCAGCGACAGAGGAGGAGCAGTTGGCATCTCTCAGCATCATCTATTCTAACTTCG
GCGACGTGATGGAAGCCGATATGGTGGTCGCGTGTCTGCGGAACGGGGCTGAGCGGCTTAGTGCCGGGAACGCGGAGGTC
CACGCAGCCCCTAATGGATAA

Upstream 100 bases:

>100_bases
CTCATATAAATTCGCACGCATCCTTGGAAGGGAATTCCAACGGCAAAAATATGAAACTCGCCGCAGCGTGATGCGGCGCA
TCATCAAGGGAGACAGGCGC

Downstream 100 bases:

>100_bases
TGCGCGAGAGTTCGTTCGCGGCGACGATGAATTTGGGCAGGACTTCAGCCTTCAGGCGCTCGAGTGACATGCGTGATACG
TGCGAGCTGCAGCCTAATGT

Product: isochorismatase hydrolase

Products: NA

Alternate protein names: Ureidoacrylate amidohydrolase [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MQFSAIPQHIVDRVVDRRGALHIHQNIDPTKTALVVIDLQNCFMVEELAFAYSCGAIKLVPIVNRVADEVRRAGGKVFWI
RNTISEDMRENWSNWFAMNGYDPERAARREVNMIVGSPGHQIHSDLVIAPQDEIVDKHRFSAFIQGSSDIDDRLRAQGID
TLIFAGIATNVCCESSARDAMMLNYKVIVVTDATAAATEEEQLASLSIIYSNFGDVMEADMVVACLRNGAERLSAGNAEV
HAAPNG

Sequences:

>Translated_246_residues
MQFSAIPQHIVDRVVDRRGALHIHQNIDPTKTALVVIDLQNCFMVEELAFAYSCGAIKLVPIVNRVADEVRRAGGKVFWI
RNTISEDMRENWSNWFAMNGYDPERAARREVNMIVGSPGHQIHSDLVIAPQDEIVDKHRFSAFIQGSSDIDDRLRAQGID
TLIFAGIATNVCCESSARDAMMLNYKVIVVTDATAAATEEEQLASLSIIYSNFGDVMEADMVVACLRNGAERLSAGNAEV
HAAPNG
>Mature_246_residues
MQFSAIPQHIVDRVVDRRGALHIHQNIDPTKTALVVIDLQNCFMVEELAFAYSCGAIKLVPIVNRVADEVRRAGGKVFWI
RNTISEDMRENWSNWFAMNGYDPERAARREVNMIVGSPGHQIHSDLVIAPQDEIVDKHRFSAFIQGSSDIDDRLRAQGID
TLIFAGIATNVCCESSARDAMMLNYKVIVVTDATAAATEEEQLASLSIIYSNFGDVMEADMVVACLRNGAERLSAGNAEV
HAAPNG

Specific function: In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby rele

COG id: COG1335

COG function: function code Q; Amidases related to nicotinamidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismatase family. RutB subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081820, Length=219, Percent_Identity=31.0502283105023, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87081992, Length=203, Percent_Identity=27.5862068965517, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019916
- InterPro:   IPR000868 [H]

Pfam domain/function: PF00857 Isochorismatase [H]

EC number: NA

Molecular weight: Translated: 27119; Mature: 27119

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFSAIPQHIVDRVVDRRGALHIHQNIDPTKTALVVIDLQNCFMVEELAFAYSCGAIKLV
CCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCEEHH
PIVNRVADEVRRAGGKVFWIRNTISEDMRENWSNWFAMNGYDPERAARREVNMIVGSPGH
HHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHCEEEECCCCHHHHHHHHHEEEECCCCC
QIHSDLVIAPQDEIVDKHRFSAFIQGSSDIDDRLRAQGIDTLIFAGIATNVCCESSARDA
HHCCCEEECCHHHHHHHHHHHHEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCE
MMLNYKVIVVTDATAAATEEEQLASLSIIYSNFGDVMEADMVVACLRNGAERLSAGNAEV
EEEEEEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEE
HAAPNG
EECCCC
>Mature Secondary Structure
MQFSAIPQHIVDRVVDRRGALHIHQNIDPTKTALVVIDLQNCFMVEELAFAYSCGAIKLV
CCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCEEHH
PIVNRVADEVRRAGGKVFWIRNTISEDMRENWSNWFAMNGYDPERAARREVNMIVGSPGH
HHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHCEEEECCCCHHHHHHHHHEEEECCCCC
QIHSDLVIAPQDEIVDKHRFSAFIQGSSDIDDRLRAQGIDTLIFAGIATNVCCESSARDA
HHCCCEEECCHHHHHHHHHHHHEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCE
MMLNYKVIVVTDATAAATEEEQLASLSIIYSNFGDVMEADMVVACLRNGAERLSAGNAEV
EEEEEEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEE
HAAPNG
EECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA