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The map label for this gene is trxB [H]

Identifier: 110634461

GI number: 110634461

Start: 2269240

End: 2270214

Strand: Reverse

Name: trxB [H]

Synonym: Meso_2112

Alternate gene names: 110634461

Gene position: 2270214-2269240 (Counterclockwise)

Preceding gene: 110634463

Following gene: 110634460

Centisome position: 51.45

GC content: 61.74

Gene sequence:

>975_bases
ATGACCACCCGCCACGCGCCAGTTCTGATAATCGGATCAGGACCGGCCGGCTACACTGCGGCCATTTATGCCGCGCGCGC
CATGCTGAAGCCTCTTCTGGTTTCCGGCCTGGAGCAAGGCGGTCAGCTCATGATCACGACGGAGGTGGAGAACTATCCCG
GTTTCGCCGAGCCCATTCAGGGCCCGTGGCTCATGGAGCAAATGCGGCTGCAGGCGGAGCATGTGGGCACGGAGATCGTG
AATGATCTGATCGTGGAAGCGGATATCCGGTCGCGGCCCTTTCGGCTGAAGGGCGACTCCGGCACGGTTTATACCTGTGA
TGCTCTCATCATCGCCACCGGCGCAAAGGCGAGATGGCTCGGGCTGCCATCAGAAAATACTTTCATGGGCTTCGGTCTTT
CGGCTTGCGCGACCTGTGACGGCTTTTTCTATCGCGGCAAGGAAGTTGTCGTCATCGGAGGCGGCAACACGGCGGTCGAA
GAGGCTCTTTATCTCTCAAATCTGGCAAAGCGTGTAACCGTCATCCACCGGCGCGGCGAATTCCGGGCCGAGCGCATCCT
GCAGGAGCGGCTCCTGCGGAAGGAAAACGTGGAAATCATGTGGGATACGGTCGTGGACGAAATCCTCGGCGAAACCCCAA
AGCCACCTCTGCCGCCATCCGTCACCGGCATTCGCGTTCAAAACGTGCAGACGGGCGAGGTGCGCGACCTTCCGGTGGAC
GGTGTTTTCGTCGCCATCGGCCACGCGCCTGCCGTCGAGCTATTCGAAGGCAAGCTCAAGCAGAAGCCGAACGGGTATCT
CTGGACCGAGCCGAATTCGACCCGCACGGATGTGCCCGGTGTCTTTGCGGCGGGCGACGTTGCCGACGATGTCTACCGGC
AGGCGGTAACGGCGGCAGGGCTTGGCTGCATGGCGGCGCTGGAGGCGGAGCGATATTTGGCGGAATTGGAGACGCACCGC
GAGGCCGCCGAATAG

Upstream 100 bases:

>100_bases
CAAACCGTCCTTCGCCTTGCAGAAAGTGGTATGCGATACTTAGATCTACGCAGCTGTATGCCTTTTGCGCTGCATGCCGA
ACCAGGAAAGGACCCGAGCC

Downstream 100 bases:

>100_bases
TCCGGCTCAGCTGCGCGCCTTATAAAAGCGAGGGGATCGGGCGTTGGATTGGGACAAGCTACGTGTATTCCATGCTGCCG
CGGCGGCAGGATCCTTTACG

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTTRHAPVLIIGSGPAGYTAAIYAARAMLKPLLVSGLEQGGQLMITTEVENYPGFAEPIQGPWLMEQMRLQAEHVGTEIV
NDLIVEADIRSRPFRLKGDSGTVYTCDALIIATGAKARWLGLPSENTFMGFGLSACATCDGFFYRGKEVVVIGGGNTAVE
EALYLSNLAKRVTVIHRRGEFRAERILQERLLRKENVEIMWDTVVDEILGETPKPPLPPSVTGIRVQNVQTGEVRDLPVD
GVFVAIGHAPAVELFEGKLKQKPNGYLWTEPNSTRTDVPGVFAAGDVADDVYRQAVTAAGLGCMAALEAERYLAELETHR
EAAE

Sequences:

>Translated_324_residues
MTTRHAPVLIIGSGPAGYTAAIYAARAMLKPLLVSGLEQGGQLMITTEVENYPGFAEPIQGPWLMEQMRLQAEHVGTEIV
NDLIVEADIRSRPFRLKGDSGTVYTCDALIIATGAKARWLGLPSENTFMGFGLSACATCDGFFYRGKEVVVIGGGNTAVE
EALYLSNLAKRVTVIHRRGEFRAERILQERLLRKENVEIMWDTVVDEILGETPKPPLPPSVTGIRVQNVQTGEVRDLPVD
GVFVAIGHAPAVELFEGKLKQKPNGYLWTEPNSTRTDVPGVFAAGDVADDVYRQAVTAAGLGCMAALEAERYLAELETHR
EAAE
>Mature_323_residues
TTRHAPVLIIGSGPAGYTAAIYAARAMLKPLLVSGLEQGGQLMITTEVENYPGFAEPIQGPWLMEQMRLQAEHVGTEIVN
DLIVEADIRSRPFRLKGDSGTVYTCDALIIATGAKARWLGLPSENTFMGFGLSACATCDGFFYRGKEVVVIGGGNTAVEE
ALYLSNLAKRVTVIHRRGEFRAERILQERLLRKENVEIMWDTVVDEILGETPKPPLPPSVTGIRVQNVQTGEVRDLPVDG
VFVAIGHAPAVELFEGKLKQKPNGYLWTEPNSTRTDVPGVFAAGDVADDVYRQAVTAAGLGCMAALEAERYLAELETHRE
AAE

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=323, Percent_Identity=57.5851393188854, Blast_Score=361, Evalue=1e-101,
Organism=Escherichia coli, GI87081763, Length=315, Percent_Identity=32.3809523809524, Blast_Score=151, Evalue=7e-38,
Organism=Saccharomyces cerevisiae, GI6320560, Length=323, Percent_Identity=45.2012383900929, Blast_Score=283, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6321898, Length=323, Percent_Identity=44.5820433436532, Blast_Score=281, Evalue=1e-76,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 35225; Mature: 35094

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRHAPVLIIGSGPAGYTAAIYAARAMLKPLLVSGLEQGGQLMITTEVENYPGFAEPIQ
CCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCC
GPWLMEQMRLQAEHVGTEIVNDLIVEADIRSRPFRLKGDSGTVYTCDALIIATGAKARWL
CCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEECCCCCEEEECEEEEECCCCEEEE
GLPSENTFMGFGLSACATCDGFFYRGKEVVVIGGGNTAVEEALYLSNLAKRVTVIHRRGE
ECCCCCCEEECCHHHHHHHCCCEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCH
FRAERILQERLLRKENVEIMWDTVVDEILGETPKPPLPPSVTGIRVQNVQTGEVRDLPVD
HHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCC
GVFVAIGHAPAVELFEGKLKQKPNGYLWTEPNSTRTDVPGVFAAGDVADDVYRQAVTAAG
CEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHHC
LGCMAALEAERYLAELETHREAAE
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTRHAPVLIIGSGPAGYTAAIYAARAMLKPLLVSGLEQGGQLMITTEVENYPGFAEPIQ
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCC
GPWLMEQMRLQAEHVGTEIVNDLIVEADIRSRPFRLKGDSGTVYTCDALIIATGAKARWL
CCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEECCCCCEEEECEEEEECCCCEEEE
GLPSENTFMGFGLSACATCDGFFYRGKEVVVIGGGNTAVEEALYLSNLAKRVTVIHRRGE
ECCCCCCEEECCHHHHHHHCCCEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCH
FRAERILQERLLRKENVEIMWDTVVDEILGETPKPPLPPSVTGIRVQNVQTGEVRDLPVD
HHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCC
GVFVAIGHAPAVELFEGKLKQKPNGYLWTEPNSTRTDVPGVFAAGDVADDVYRQAVTAAG
CEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHHC
LGCMAALEAERYLAELETHREAAE
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA