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The map label for this gene is yafC [H]

Identifier: 110634460

GI number: 110634460

Start: 2268306

End: 2269196

Strand: Reverse

Name: yafC [H]

Synonym: Meso_2111

Alternate gene names: 110634460

Gene position: 2269196-2268306 (Counterclockwise)

Preceding gene: 110634461

Following gene: 110634457

Centisome position: 51.43

GC content: 59.15

Gene sequence:

>891_bases
TTGGATTGGGACAAGCTACGTGTATTCCATGCTGCCGCGGCGGCAGGATCCTTTACGCACGCCGCGGAGTCGCTCCATCT
GTCGCAGTCAGCGATTTCAAGGCAAGTAAGCGCGCTTGAGCAGGAACTTGGAGTGAGCCTGTTTCATCGCCATGCGCGCG
GCCTCGTGCTCACGGAGCAGGGGGAAATGCTCTACCGCACCGCGCACGATGTCCTTATGAAGCTCGAGACGGTGAAGGTG
CGGCTTTCGGAGGCCAAGGACCGTCCCTCGGGCGTGCTGCGCGTCTCGACCACCGTCGGCTTGGGTAATGGATGGCTGAC
GGAGCGCCTGCCGGAATTCGGCGCGCTTTACCCGGACATCCAGCTCCAGGTGATCCTCGACAACGAGGAGCTTGACCTTA
CCATGCGGCAGGCCGATTGCGCCTTGCGCATGCGGCAGCCGCAGCAGCCGGATCTGATCCAGCGCAAGCTCTTCACGGTC
CATTTCCATCTATACGCATCGCCTGCCTATCTGAACCGCTACGGCAAGCCTAACTCGATCGACGAATTGGATCGGCATCG
TATCGTGATCTTCGGCGAGACGGTGCCGCCGCATTTGAGCGACATGAATTGGCTGGAGACGGCCGGCAGGCCGGAAGGAT
CGAAACGCGCCGCCGCGCTCCAGATCAACAACATTCTTTCAATAAAGATCGCGGTACAGCGAGGGGCCGGCATCGCCATC
TTGCCGGATTATGCCGTGGGCAGCGACAGCGGCCTTGTGCAGCTTTTGCCGGAAACTGAAGTGCCGTCCTTCGACACGTA
TTTCTGCTACCCGGACACGATGAAAAATCAGGCAAAAATGCAGGTCTTCAGGGACTTCCTGATTTCCAAATCGAGAGGCT
GGATCTACTAG

Upstream 100 bases:

>100_bases
CTGGAGGCGGAGCGATATTTGGCGGAATTGGAGACGCACCGCGAGGCCGCCGAATAGTCCGGCTCAGCTGCGCGCCTTAT
AAAAGCGAGGGGATCGGGCG

Downstream 100 bases:

>100_bases
GCCGCGGCGATTCTACAATCGGCTGCGCCGCAGCGAAATTCCGCCGGTTCTAGGACTCACAGGGGACTGTAGATCGCTCA
ATCTGTGCATCGTGCTTTCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MDWDKLRVFHAAAAAGSFTHAAESLHLSQSAISRQVSALEQELGVSLFHRHARGLVLTEQGEMLYRTAHDVLMKLETVKV
RLSEAKDRPSGVLRVSTTVGLGNGWLTERLPEFGALYPDIQLQVILDNEELDLTMRQADCALRMRQPQQPDLIQRKLFTV
HFHLYASPAYLNRYGKPNSIDELDRHRIVIFGETVPPHLSDMNWLETAGRPEGSKRAAALQINNILSIKIAVQRGAGIAI
LPDYAVGSDSGLVQLLPETEVPSFDTYFCYPDTMKNQAKMQVFRDFLISKSRGWIY

Sequences:

>Translated_296_residues
MDWDKLRVFHAAAAAGSFTHAAESLHLSQSAISRQVSALEQELGVSLFHRHARGLVLTEQGEMLYRTAHDVLMKLETVKV
RLSEAKDRPSGVLRVSTTVGLGNGWLTERLPEFGALYPDIQLQVILDNEELDLTMRQADCALRMRQPQQPDLIQRKLFTV
HFHLYASPAYLNRYGKPNSIDELDRHRIVIFGETVPPHLSDMNWLETAGRPEGSKRAAALQINNILSIKIAVQRGAGIAI
LPDYAVGSDSGLVQLLPETEVPSFDTYFCYPDTMKNQAKMQVFRDFLISKSRGWIY
>Mature_296_residues
MDWDKLRVFHAAAAAGSFTHAAESLHLSQSAISRQVSALEQELGVSLFHRHARGLVLTEQGEMLYRTAHDVLMKLETVKV
RLSEAKDRPSGVLRVSTTVGLGNGWLTERLPEFGALYPDIQLQVILDNEELDLTMRQADCALRMRQPQQPDLIQRKLFTV
HFHLYASPAYLNRYGKPNSIDELDRHRIVIFGETVPPHLSDMNWLETAGRPEGSKRAAALQINNILSIKIAVQRGAGIAI
LPDYAVGSDSGLVQLLPETEVPSFDTYFCYPDTMKNQAKMQVFRDFLISKSRGWIY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=31.0344827586207, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI87081978, Length=287, Percent_Identity=28.9198606271777, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI145693193, Length=293, Percent_Identity=27.6450511945392, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789440, Length=292, Percent_Identity=28.4246575342466, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787128, Length=295, Percent_Identity=27.7966101694915, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789639, Length=299, Percent_Identity=26.7558528428094, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787589, Length=239, Percent_Identity=28.8702928870293, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789173, Length=298, Percent_Identity=27.5167785234899, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788706, Length=180, Percent_Identity=30.5555555555556, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI157672245, Length=116, Percent_Identity=38.7931034482759, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786448, Length=175, Percent_Identity=29.7142857142857, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790262, Length=140, Percent_Identity=33.5714285714286, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788887, Length=296, Percent_Identity=28.0405405405405, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788626, Length=311, Percent_Identity=26.6881028938907, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786713, Length=119, Percent_Identity=35.2941176470588, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790399, Length=259, Percent_Identity=25.8687258687259, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33329; Mature: 33329

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWDKLRVFHAAAAAGSFTHAAESLHLSQSAISRQVSALEQELGVSLFHRHARGLVLTEQ
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECC
GEMLYRTAHDVLMKLETVKVRLSEAKDRPSGVLRVSTTVGLGNGWLTERLPEFGALYPDI
CCHHHHHHHHHHHHHHHHEEEEHHCCCCCCCEEEEEEEEECCCCHHHHHCHHHCCCCCCE
QLQVILDNEELDLTMRQADCALRMRQPQQPDLIQRKLFTVHFHLYASPAYLNRYGKPNSI
EEEEEECCCCCEEEEHHHHHHHHHCCCCCCCHHHHEEEEEEEEEEECHHHHHCCCCCCCC
DELDRHRIVIFGETVPPHLSDMNWLETAGRPEGSKRAAALQINNILSIKIAVQRGAGIAI
CCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCCCCEEEEEECCEEEEEEEEECCCCEEE
LPDYAVGSDSGLVQLLPETEVPSFDTYFCYPDTMKNQAKMQVFRDFLISKSRGWIY
ECCCCCCCCCCEEEECCCCCCCCCCEEEECCHHHCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDWDKLRVFHAAAAAGSFTHAAESLHLSQSAISRQVSALEQELGVSLFHRHARGLVLTEQ
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECC
GEMLYRTAHDVLMKLETVKVRLSEAKDRPSGVLRVSTTVGLGNGWLTERLPEFGALYPDI
CCHHHHHHHHHHHHHHHHEEEEHHCCCCCCCEEEEEEEEECCCCHHHHHCHHHCCCCCCE
QLQVILDNEELDLTMRQADCALRMRQPQQPDLIQRKLFTVHFHLYASPAYLNRYGKPNSI
EEEEEECCCCCEEEEHHHHHHHHHCCCCCCCHHHHEEEEEEEEEEECHHHHHCCCCCCCC
DELDRHRIVIFGETVPPHLSDMNWLETAGRPEGSKRAAALQINNILSIKIAVQRGAGIAI
CCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCCCCEEEEEECCEEEEEEEEECCCCEEE
LPDYAVGSDSGLVQLLPETEVPSFDTYFCYPDTMKNQAKMQVFRDFLISKSRGWIY
ECCCCCCCCCCEEEECCCCCCCCCCEEEECCHHHCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]