Click here to switch to the map view.

The map label for this gene is yfdE [H]

Identifier: 110634386

GI number: 110634386

Start: 2188518

End: 2189690

Strand: Direct

Name: yfdE [H]

Synonym: Meso_2036

Alternate gene names: 110634386

Gene position: 2188518-2189690 (Clockwise)

Preceding gene: 110634384

Following gene: 110634387

Centisome position: 49.6

GC content: 61.81

Gene sequence:

>1173_bases
ATGGCCGAACCGCCGCTTTCCAATATCCGTGTCATCGAGCTTGCCCGCATTCTCGCAGGCCCCTGGGCAGGCCAGCTTCT
GGCCGATCTCGGCGCCGAAGTTATCAAGGTCGAAAACCCGGACGGGGGCGATGACACCCGCAAATGGGGCCCGCCCTTCG
TGACGGGAAAGGACGGAGAGAACCTTTCGGCCGCCTATTTTCATTCCTGCAACAGGGGAAAGCGCTCGATCGCGCTTGAT
TTCACGAGGGAGGAAGACCGCGCGGTTCTCCTGAAGCTGATCGCCTCGGCCGACGTGCTGATCGAGAACTTCAAGCTCGG
CGGCCTAAAAAAATACGGCCTCGATTACGAGAGCCTGAAGGCGATCAACCCGCGCCTCGTCTACTGCTCCATCACCGGAT
TCGGGCAGGATGGACCCTATGCTCCGCGTGCGGGCTATGATTTCATCATACAGGGCATGTCCGGCCTGATGTCGATCACC
GGGCCCGCCGACGGCGAGCCGCAGAAGGTGGGTGTTGCCGTCACCGATATCTTCACCGGCCTTTATTCCGTCATCGCAAT
TCAGGCGGCGCTCCGCCACGCGGAAAAGACCGGCGAGGGGCAGCATATCGACATGGCGCTGTTCGATACGCAGGTTTCGG
TGCTCGCCAACCAGAACCTGAATTATTTGGTCTCCGGCATCGCCCCGGTCCGCATGGGCAATGCGCATCCCAATATCTCC
CCTTACGAGGTCTTCGAGGTGGTGGACGGGCATTTCATCCTGGCTGTCGGCAATGACGGGCAGTTCGAGCGTTTCTGCGC
CGTAATAGGCCGCGAGGAACTGGCGGCCAATCCTGAATTCTCCACCAACGCCGCGCGCGTCGCCAACCGCGAGCGGCTCA
GGAGCGAAATCGCGCTGAGGCTGAAGACATTCGCACGCGATCTGCTCCTTAAAAGCCTCGAAGAGGCGGGCGTGCCGGCA
AGCCCCATTAACACGATCGCCGACATGTTCGCCGACCCGCAGACCATCGCCCGCGGAATGCGGCTCGACCTGAAGGACGC
GGACGGCAACGCGCTTCCCTCCGTGCGCGCGCCGATGGTCATGTCGCAAACCCCGCTTGCCTATACGCGCCCAAGCCCGC
GGCTGGGCGAACATACCGAGGAAATCCTGCGCGAACTGGAGGAAAGCACGTGA

Upstream 100 bases:

>100_bases
TTCCAACACAAACGACGGTAGGGCTTTGATGTTTCATGGCGTTGGGGGGCGAAATCGCCCTTTCCGTGCCTCTCACCGAG
AGAATGGAGCAGCAAGGACG

Downstream 100 bases:

>100_bases
AGAGCGGCGGTCAACTCATCGTCGAAGCCTTGGAAGCAAATGGCGTGGATCGCCTCTACTGCGTGCCGGGCGAAAGCTAT
CTGGCAGTGCTCGACGCGCT

Product: L-carnitine dehydratase/bile acid-inducible protein F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MAEPPLSNIRVIELARILAGPWAGQLLADLGAEVIKVENPDGGDDTRKWGPPFVTGKDGENLSAAYFHSCNRGKRSIALD
FTREEDRAVLLKLIASADVLIENFKLGGLKKYGLDYESLKAINPRLVYCSITGFGQDGPYAPRAGYDFIIQGMSGLMSIT
GPADGEPQKVGVAVTDIFTGLYSVIAIQAALRHAEKTGEGQHIDMALFDTQVSVLANQNLNYLVSGIAPVRMGNAHPNIS
PYEVFEVVDGHFILAVGNDGQFERFCAVIGREELAANPEFSTNAARVANRERLRSEIALRLKTFARDLLLKSLEEAGVPA
SPINTIADMFADPQTIARGMRLDLKDADGNALPSVRAPMVMSQTPLAYTRPSPRLGEHTEEILRELEEST

Sequences:

>Translated_390_residues
MAEPPLSNIRVIELARILAGPWAGQLLADLGAEVIKVENPDGGDDTRKWGPPFVTGKDGENLSAAYFHSCNRGKRSIALD
FTREEDRAVLLKLIASADVLIENFKLGGLKKYGLDYESLKAINPRLVYCSITGFGQDGPYAPRAGYDFIIQGMSGLMSIT
GPADGEPQKVGVAVTDIFTGLYSVIAIQAALRHAEKTGEGQHIDMALFDTQVSVLANQNLNYLVSGIAPVRMGNAHPNIS
PYEVFEVVDGHFILAVGNDGQFERFCAVIGREELAANPEFSTNAARVANRERLRSEIALRLKTFARDLLLKSLEEAGVPA
SPINTIADMFADPQTIARGMRLDLKDADGNALPSVRAPMVMSQTPLAYTRPSPRLGEHTEEILRELEEST
>Mature_389_residues
AEPPLSNIRVIELARILAGPWAGQLLADLGAEVIKVENPDGGDDTRKWGPPFVTGKDGENLSAAYFHSCNRGKRSIALDF
TREEDRAVLLKLIASADVLIENFKLGGLKKYGLDYESLKAINPRLVYCSITGFGQDGPYAPRAGYDFIIQGMSGLMSITG
PADGEPQKVGVAVTDIFTGLYSVIAIQAALRHAEKTGEGQHIDMALFDTQVSVLANQNLNYLVSGIAPVRMGNAHPNISP
YEVFEVVDGHFILAVGNDGQFERFCAVIGREELAANPEFSTNAARVANRERLRSEIALRLKTFARDLLLKSLEEAGVPAS
PINTIADMFADPQTIARGMRLDLKDADGNALPSVRAPMVMSQTPLAYTRPSPRLGEHTEEILRELEEST

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=383, Percent_Identity=41.5143603133159, Blast_Score=306, Evalue=2e-83,
Organism=Homo sapiens, GI300863124, Length=408, Percent_Identity=39.9509803921569, Blast_Score=294, Evalue=9e-80,
Organism=Homo sapiens, GI13376042, Length=408, Percent_Identity=36.7647058823529, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI300863126, Length=383, Percent_Identity=35.509138381201, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI266456254, Length=383, Percent_Identity=25.8485639686684, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI42794625, Length=383, Percent_Identity=25.8485639686684, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI266458397, Length=254, Percent_Identity=31.1023622047244, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI266458393, Length=254, Percent_Identity=31.1023622047244, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI266458395, Length=184, Percent_Identity=31.5217391304348, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI42822893, Length=184, Percent_Identity=31.5217391304348, Blast_Score=89, Evalue=5e-18,
Organism=Escherichia coli, GI87082093, Length=383, Percent_Identity=38.6422976501305, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1788717, Length=407, Percent_Identity=30.7125307125307, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1786222, Length=393, Percent_Identity=25.6997455470738, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI115535051, Length=299, Percent_Identity=24.4147157190635, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI32564160, Length=152, Percent_Identity=30.2631578947368, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648431, Length=382, Percent_Identity=45.0261780104712, Blast_Score=308, Evalue=3e-84,
Organism=Drosophila melanogaster, GI24585488, Length=211, Percent_Identity=30.3317535545024, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 42366; Mature: 42235

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEPPLSNIRVIELARILAGPWAGQLLADLGAEVIKVENPDGGDDTRKWGPPFVTGKDGE
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEEECCCCC
NLSAAYFHSCNRGKRSIALDFTREEDRAVLLKLIASADVLIENFKLGGLKKYGLDYESLK
CCCHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHH
AINPRLVYCSITGFGQDGPYAPRAGYDFIIQGMSGLMSITGPADGEPQKVGVAVTDIFTG
CCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCCEECCHHHHHHHH
LYSVIAIQAALRHAEKTGEGQHIDMALFDTQVSVLANQNLNYLVSGIAPVRMGNAHPNIS
HHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHCCCCCEEHHCCCCEEECCCCCCCC
PYEVFEVVDGHFILAVGNDGQFERFCAVIGREELAANPEFSTNAARVANRERLRSEIALR
HHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
LKTFARDLLLKSLEEAGVPASPINTIADMFADPQTIARGMRLDLKDADGNALPSVRAPMV
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHCCCEEEEECCCCCCCCCCCCCEE
MSQTPLAYTRPSPRLGEHTEEILRELEEST
ECCCCCEECCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEPPLSNIRVIELARILAGPWAGQLLADLGAEVIKVENPDGGDDTRKWGPPFVTGKDGE
CCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCCEEECCCCC
NLSAAYFHSCNRGKRSIALDFTREEDRAVLLKLIASADVLIENFKLGGLKKYGLDYESLK
CCCHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHH
AINPRLVYCSITGFGQDGPYAPRAGYDFIIQGMSGLMSITGPADGEPQKVGVAVTDIFTG
CCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCCEECCHHHHHHHH
LYSVIAIQAALRHAEKTGEGQHIDMALFDTQVSVLANQNLNYLVSGIAPVRMGNAHPNIS
HHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHCCCCCEEHHCCCCEEECCCCCCCC
PYEVFEVVDGHFILAVGNDGQFERFCAVIGREELAANPEFSTNAARVANRERLRSEIALR
HHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
LKTFARDLLLKSLEEAGVPASPINTIADMFADPQTIARGMRLDLKDADGNALPSVRAPMV
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHCCCEEEEECCCCCCCCCCCCCEE
MSQTPLAYTRPSPRLGEHTEEILRELEEST
ECCCCCEECCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]