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The map label for this gene is mraY

Identifier: 110634360

GI number: 110634360

Start: 2157530

End: 2158612

Strand: Reverse

Name: mraY

Synonym: Meso_2010

Alternate gene names: 110634360

Gene position: 2158612-2157530 (Counterclockwise)

Preceding gene: 110634361

Following gene: 110634359

Centisome position: 48.92

GC content: 60.02

Gene sequence:

>1083_bases
ATGTTGATGCTGCTGGTTGCACTCGCCGATGAATTCTCGGTGCTAAATGTTTTTCGCTACATAACCTTTCGCACCGGAGG
CGCGCTGATAACGGCTGCATTCATCGTCTTCCTCTTCGGGCCAGCGATCATCAGCTCGCTGCGGCTTCGCCAGGGCAAAG
GCCAGCCGATCCGGGCTGACGGGCCGCAGACCCATTTCAAGAAGGCCGGCACGCCCACGATGGGCGGACTGATGATCTTT
TCCGGTATCCTGGGCTCATCCATTCTGTGGGGCAATCTGTCCAGCGTTTACGTCTGGGTGGTGCTGATGGTCATGGTCGG
TTTCGGCGCCATCGGCTTCTACGACGATTATCTGAAGGTCACGAAGCAGTCGCATCTGGGCTTTTCCGGGAAATCCCGTC
TGGCGCTCGAATTCGTGATAGCGGGCTTTGCCGCCTGGATCATCATGAGCGCGGGGCAGGAGCCGTTCTCCTCCTCGCTC
ACTTTCCCATTCTTCAAGGAACTGCTGCTCAATCTCGGAATCTTCTTCATCCCCTTCGCCGCCTTCGTGATCGTCGGCGC
AGGCAACGCGGTCAATCTCACCGACGGCCTTGACGGGCTCGCCACGGTGCCGGTGATGGTGGCGGCCGCCTCCTTCGGCG
TGATCGCCTATCTGTCGGGAAATGCGATCTTCGCGGATTACCTGCAGATCCATTTCGTGCCGGGAACGGGCGAACTCTCG
GTCATCCTTGGCGCGGTGATCGGCGCCGGGCTCGGCTTCCTCTGGTTCAACGCGCCGCCGGCGGCGATCTTCATGGGCGA
TACCGGTTCGCTGGCGCTCGGCGGGCTTATCGGCACCGTGGCGGTAGCGACCAAACACGAGATTGTGCTTGCCATTATCG
GTGGCCTTTTCGTGATCGAGATTCTGTCCGTCATCATCCAGGTCGCCGTCTTCAAGATGACCGGCAAGCGCGTCTTCCTC
ATGGCGCCGATCCACCATCACTTCGAAAAGCTCGGCTGGACGGAGAGCCAGGTCGTGATCCGGTTCTGGATCATTGCCGT
CGTCCTGGCGCTGATCGGGCTTTCAACGCTGAAGCTGCGGTAG

Upstream 100 bases:

>100_bases
CCTGTCCAGGCTGGTCGACGTACTTTTGAAGAATTATCCGGCGGCGGTCGATGAACCGGGCCGGGTTTGATAGCGCGGAC
AGGCGCGGGGGCTGTTTTCG

Downstream 100 bases:

>100_bases
GGGGTGGGAATGGTCCGGCTGTGTATCCAGGTGGGGCTTTTCCAATGATCCCCGCCACCACCTTCCACGGCAGACAAGTC
GCGCTGTTCGGCCTCGGCGG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MLMLLVALADEFSVLNVFRYITFRTGGALITAAFIVFLFGPAIISSLRLRQGKGQPIRADGPQTHFKKAGTPTMGGLMIF
SGILGSSILWGNLSSVYVWVVLMVMVGFGAIGFYDDYLKVTKQSHLGFSGKSRLALEFVIAGFAAWIIMSAGQEPFSSSL
TFPFFKELLLNLGIFFIPFAAFVIVGAGNAVNLTDGLDGLATVPVMVAAASFGVIAYLSGNAIFADYLQIHFVPGTGELS
VILGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGLIGTVAVATKHEIVLAIIGGLFVIEILSVIIQVAVFKMTGKRVFL
MAPIHHHFEKLGWTESQVVIRFWIIAVVLALIGLSTLKLR

Sequences:

>Translated_360_residues
MLMLLVALADEFSVLNVFRYITFRTGGALITAAFIVFLFGPAIISSLRLRQGKGQPIRADGPQTHFKKAGTPTMGGLMIF
SGILGSSILWGNLSSVYVWVVLMVMVGFGAIGFYDDYLKVTKQSHLGFSGKSRLALEFVIAGFAAWIIMSAGQEPFSSSL
TFPFFKELLLNLGIFFIPFAAFVIVGAGNAVNLTDGLDGLATVPVMVAAASFGVIAYLSGNAIFADYLQIHFVPGTGELS
VILGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGLIGTVAVATKHEIVLAIIGGLFVIEILSVIIQVAVFKMTGKRVFL
MAPIHHHFEKLGWTESQVVIRFWIIAVVLALIGLSTLKLR
>Mature_360_residues
MLMLLVALADEFSVLNVFRYITFRTGGALITAAFIVFLFGPAIISSLRLRQGKGQPIRADGPQTHFKKAGTPTMGGLMIF
SGILGSSILWGNLSSVYVWVVLMVMVGFGAIGFYDDYLKVTKQSHLGFSGKSRLALEFVIAGFAAWIIMSAGQEPFSSSL
TFPFFKELLLNLGIFFIPFAAFVIVGAGNAVNLTDGLDGLATVPVMVAAASFGVIAYLSGNAIFADYLQIHFVPGTGELS
VILGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGLIGTVAVATKHEIVLAIIGGLFVIEILSVIIQVAVFKMTGKRVFL
MAPIHHHFEKLGWTESQVVIRFWIIAVVLALIGLSTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=361, Percent_Identity=50.6925207756233, Blast_Score=340, Evalue=7e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_MESSB (Q11GS2)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_674568.1
- STRING:   Q11GS2
- GeneID:   4182803
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_2010
- NMPDR:   fig|266779.1.peg.605
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- PhylomeDB:   Q11GS2
- ProtClustDB:   PRK00108
- BioCyc:   MSP266779:MESO_2010-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 38398; Mature: 38398

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x143edffc)-; HASH(0x456970a0)-; HASH(0x144c9b90)-; HASH(0x455f96a8)-; HASH(0x12eb18c8)-; HASH(0x144c401c)-; HASH(0x456ae8d8)-; HASH(0x14793698)-; HASH(0x4564ec38)-; HASH(0x45653678)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMLLVALADEFSVLNVFRYITFRTGGALITAAFIVFLFGPAIISSLRLRQGKGQPIRAD
CCEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GPQTHFKKAGTPTMGGLMIFSGILGSSILWGNLSSVYVWVVLMVMVGFGAIGFYDDYLKV
CCHHHHHCCCCCCHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
TKQSHLGFSGKSRLALEFVIAGFAAWIIMSAGQEPFSSSLTFPFFKELLLNLGIFFIPFA
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AFVIVGAGNAVNLTDGLDGLATVPVMVAAASFGVIAYLSGNAIFADYLQIHFVPGTGELS
HHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCEEEEEECCEEEEEEEEEEEECCCCHHH
VILGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGLIGTVAVATKHEIVLAIIGGLFVIE
HHHHHHHHCCHHEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSVIIQVAVFKMTGKRVFLMAPIHHHFEKLGWTESQVVIRFWIIAVVLALIGLSTLKLR
HHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHCCH
>Mature Secondary Structure
MLMLLVALADEFSVLNVFRYITFRTGGALITAAFIVFLFGPAIISSLRLRQGKGQPIRAD
CCEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GPQTHFKKAGTPTMGGLMIFSGILGSSILWGNLSSVYVWVVLMVMVGFGAIGFYDDYLKV
CCHHHHHCCCCCCHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
TKQSHLGFSGKSRLALEFVIAGFAAWIIMSAGQEPFSSSLTFPFFKELLLNLGIFFIPFA
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AFVIVGAGNAVNLTDGLDGLATVPVMVAAASFGVIAYLSGNAIFADYLQIHFVPGTGELS
HHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCEEEEEECCEEEEEEEEEEEECCCCHHH
VILGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGLIGTVAVATKHEIVLAIIGGLFVIE
HHHHHHHHCCHHEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSVIIQVAVFKMTGKRVFLMAPIHHHFEKLGWTESQVVIRFWIIAVVLALIGLSTLKLR
HHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA