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The map label for this gene is ftsW [H]

Identifier: 110634358

GI number: 110634358

Start: 2154931

End: 2156085

Strand: Reverse

Name: ftsW [H]

Synonym: Meso_2008

Alternate gene names: 110634358

Gene position: 2156085-2154931 (Counterclockwise)

Preceding gene: 110634359

Following gene: 110634357

Centisome position: 48.86

GC content: 63.12

Gene sequence:

>1155_bases
ATGATCAGCCGTACCGACCGCTCCATGGTGGCGAACTGGTGGTGGACTGTCGACCGATGGTTCCTTGCCGCATTCCTCTT
TCTCATGGGACTCGGCGTCGTGCTTTCCTTCGCCGCGAGCCCGGCGGTGGCCGAGCGCATCGGCCTTGAGAGCTATCATT
TCGTGACACGCCAGATCGTCTACATGATCCCGGCGCTGGTGGTTCTAATCGGCATTTCCTTCCTCAATCCGCGCCAGGTG
CGTCGGGTCGCCCTCGCGATGCTCTGCATCGCGCTCCTGCTCATGGTGGCGACGCTCTTTTTCGGCATGGAGGTTAAGGG
CTCGCGGCGCTGGATCCATCTTTTCGGCCTGTCGATCCAGCCTTCCGAATATATGAAGCCTGCTTTCGTGGTGATCTGCG
CGTGGCTCTTCGCCGAGCACGCGCGGCAGCCGGAGATTCCCGGCAATCTCTTTGCCATGCTGCTCCTCGGTCTCGTCGCG
GCCTTGCTTGTCGCCCAGCCGGATCTCGGGCAGACCATGCTCGTTCTTGCCACCTGGGGCGCGATGTTTTTCATCGCCGG
CATGCCATGGCTGTGGATCCTCGTGCTCGGCGCGCTGGGCGCTGCCGGTGCGGTCGCCGCCTATGTCGTTTTTCCGCATG
TGGCCGAGCGTATCGATCGCTTCGTCACCGGGGAAGGAGACACCTATCAGGTGGATATGAGCCTGGAGGCGCTGACGCGC
GGCGGCTGGCTCGGCCAGGGTCCGGGCGAGGGCTCAGTCAAGCGCATCCTGCCCGACAGCCACACAGACTTCGTCTTCGC
CGTGGCGGGAGAGGAATTCGGCCTCATCATGTGCCTCATCATCCTCGCCCTTTTTGCCTTCGTCGTGCTGCGGGGGCTTT
CGATCGCGCGGCGTCAGGAAGACGATTTTACGCGCTATGCGCTTTCCGGCCTCGTCGTGCTTTTCGGCCTGCAATCCATC
ATCAACATGGCCGTCAATGTCCGCATGATGCCGGCCAAGGGCATGACGCTGCCATTCATCTCCTATGGCGGCTCCTCGCT
CATTGCCATGGCCATCTCGATGGGTTTTGTGCTGGCGTTGGCGCGCCGCCGGCCGGAGAAGCGCCGGCCGGTGAGCTTCT
CCGCTATTTCCGGCAGGGCCGCGGCTGCGGGCTGA

Upstream 100 bases:

>100_bases
CGAGTTTCGATCAGTTCAGAAATTTCGAGGTCAGGGGTGAAGCGTTTCGCGATGCGGTGCGCGCCCTGCCGGGCATTGAG
CTTATTGGGGAGAAGAGGGC

Downstream 100 bases:

>100_bases
AATGGCTGGACGAACCATTCTTCTCTCCGCCGGTGGGACGGGCGGCCATCTCTTTCCGGCAGAGGCCCTAGCGCATGAAT
TGCGGGCGCGGGGCTGGTCG

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MISRTDRSMVANWWWTVDRWFLAAFLFLMGLGVVLSFAASPAVAERIGLESYHFVTRQIVYMIPALVVLIGISFLNPRQV
RRVALAMLCIALLLMVATLFFGMEVKGSRRWIHLFGLSIQPSEYMKPAFVVICAWLFAEHARQPEIPGNLFAMLLLGLVA
ALLVAQPDLGQTMLVLATWGAMFFIAGMPWLWILVLGALGAAGAVAAYVVFPHVAERIDRFVTGEGDTYQVDMSLEALTR
GGWLGQGPGEGSVKRILPDSHTDFVFAVAGEEFGLIMCLIILALFAFVVLRGLSIARRQEDDFTRYALSGLVVLFGLQSI
INMAVNVRMMPAKGMTLPFISYGGSSLIAMAISMGFVLALARRRPEKRRPVSFSAISGRAAAAG

Sequences:

>Translated_384_residues
MISRTDRSMVANWWWTVDRWFLAAFLFLMGLGVVLSFAASPAVAERIGLESYHFVTRQIVYMIPALVVLIGISFLNPRQV
RRVALAMLCIALLLMVATLFFGMEVKGSRRWIHLFGLSIQPSEYMKPAFVVICAWLFAEHARQPEIPGNLFAMLLLGLVA
ALLVAQPDLGQTMLVLATWGAMFFIAGMPWLWILVLGALGAAGAVAAYVVFPHVAERIDRFVTGEGDTYQVDMSLEALTR
GGWLGQGPGEGSVKRILPDSHTDFVFAVAGEEFGLIMCLIILALFAFVVLRGLSIARRQEDDFTRYALSGLVVLFGLQSI
INMAVNVRMMPAKGMTLPFISYGGSSLIAMAISMGFVLALARRRPEKRRPVSFSAISGRAAAAG
>Mature_384_residues
MISRTDRSMVANWWWTVDRWFLAAFLFLMGLGVVLSFAASPAVAERIGLESYHFVTRQIVYMIPALVVLIGISFLNPRQV
RRVALAMLCIALLLMVATLFFGMEVKGSRRWIHLFGLSIQPSEYMKPAFVVICAWLFAEHARQPEIPGNLFAMLLLGLVA
ALLVAQPDLGQTMLVLATWGAMFFIAGMPWLWILVLGALGAAGAVAAYVVFPHVAERIDRFVTGEGDTYQVDMSLEALTR
GGWLGQGPGEGSVKRILPDSHTDFVFAVAGEEFGLIMCLIILALFAFVVLRGLSIARRQEDDFTRYALSGLVVLFGLQSI
INMAVNVRMMPAKGMTLPFISYGGSSLIAMAISMGFVLALARRRPEKRRPVSFSAISGRAAAAG

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=364, Percent_Identity=33.5164835164835, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1786853, Length=316, Percent_Identity=31.9620253164557, Blast_Score=121, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 42071; Mature: 42071

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISRTDRSMVANWWWTVDRWFLAAFLFLMGLGVVLSFAASPAVAERIGLESYHFVTRQIV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHH
YMIPALVVLIGISFLNPRQVRRVALAMLCIALLLMVATLFFGMEVKGSRRWIHLFGLSIQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECEEC
PSEYMKPAFVVICAWLFAEHARQPEIPGNLFAMLLLGLVAALLVAQPDLGQTMLVLATWG
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AMFFIAGMPWLWILVLGALGAAGAVAAYVVFPHVAERIDRFVTGEGDTYQVDMSLEALTR
HHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHC
GGWLGQGPGEGSVKRILPDSHTDFVFAVAGEEFGLIMCLIILALFAFVVLRGLSIARRQE
CCCCCCCCCCCCHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCH
DDFTRYALSGLVVLFGLQSIINMAVNVRMMPAKGMTLPFISYGGSSLIAMAISMGFVLAL
HHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCEECCCCHHHHHHHHHHHHHHHH
ARRRPEKRRPVSFSAISGRAAAAG
HHHCCHHCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MISRTDRSMVANWWWTVDRWFLAAFLFLMGLGVVLSFAASPAVAERIGLESYHFVTRQIV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHH
YMIPALVVLIGISFLNPRQVRRVALAMLCIALLLMVATLFFGMEVKGSRRWIHLFGLSIQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECEEC
PSEYMKPAFVVICAWLFAEHARQPEIPGNLFAMLLLGLVAALLVAQPDLGQTMLVLATWG
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AMFFIAGMPWLWILVLGALGAAGAVAAYVVFPHVAERIDRFVTGEGDTYQVDMSLEALTR
HHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHC
GGWLGQGPGEGSVKRILPDSHTDFVFAVAGEEFGLIMCLIILALFAFVVLRGLSIARRQE
CCCCCCCCCCCCHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCH
DDFTRYALSGLVVLFGLQSIINMAVNVRMMPAKGMTLPFISYGGSSLIAMAISMGFVLAL
HHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCEECCCCHHHHHHHHHHHHHHHH
ARRRPEKRRPVSFSAISGRAAAAG
HHHCCHHCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]