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The map label for this gene is murG

Identifier: 110634357

GI number: 110634357

Start: 2153802

End: 2154929

Strand: Reverse

Name: murG

Synonym: Meso_2007

Alternate gene names: 110634357

Gene position: 2154929-2153802 (Counterclockwise)

Preceding gene: 110634358

Following gene: 110634356

Centisome position: 48.84

GC content: 65.34

Gene sequence:

>1128_bases
ATGGCTGGACGAACCATTCTTCTCTCCGCCGGTGGGACGGGCGGCCATCTCTTTCCGGCAGAGGCCCTAGCGCATGAATT
GCGGGCGCGGGGCTGGTCGGTGCATCTTGCCACCGACAAGCGCGCGACCCGCTTTGCCGGCACATTTCCCGCTGACGAAA
TCCACGCGATAGACTCCGCAACGTTCGGCTCGCGCAATCCCTTAGCACTTCTCAAAAGCGGGCTTTCCATCTGGCGCGGT
TTCAAACAGTCCACCGCCTTGATCAACCGCCTGAAGCCGGCGGCGGTGGTGGGATTCGGCGGCTATCCCACCCTGCCGCC
GCTCTATGCGGCGACCAGGCGCCAGGTGCCCACCCTTGTTCATGAGCAGAACGCCGTAATGGGCCGCGCCAACAAGGCGC
TCGCGCCGCGCGTGACGGCCATTGCCGGGGGATTCCTGCCCGAGAGCGACGGCCCCTTCGCATCGAAGACCGTCCTGACC
GGCAATCCGGTTCGCCCAGCGGTCATCCAGGCGTCCGGCACACCCTATGCGCCTTCCAGCGGGCGAGGGGTCTTCCGCCT
GCTCGTCTTCGGCGGCAGCCAGGGCGCGCAGTATTTCTCGCAGGTGGTGCCCGAGGCCGTCCGCCTGCTGCCTGCGACCC
TGCGGTCCCGACTCAGGATCGTGCAGCAGGCTCGACCGGAGGACGAAGGACCAGTCCGCTCCGCCTACGACGAACTGGGC
GTGAAGGCGGAGGTTTCCCCCTTCTTCACCGATCTTGCCAGCCGAATCGCCGATGCGCATCTGGTTATTTCCCGTTCAGG
CGCTTCCACGGTATCCGAGATTGCAGTCATAGGCCGTCCGGCCATTCTCGTGCCTTATCCTTACGCGCTCGATCACGACC
AGGCCGCCAACGCGACTGCGCTCGAACGCGCGGGCGGCGCAGAGATCGTGCCGCAGGAGAAGCTTTCGGCCGAGCGGTTG
CGCGGGCTCCTGGAAGTGGCCATGGGTGCGCCGGATAAACTCGCCGCCATGGCCGCGGCGGCGAAAAGCGTCGGCCGGCC
GGATGCTTCGAGATTGCTGGCGGACGTTACGGAAGCTATTGCATCGGGGGAGACTGTTACAGAGTTCAAACGGAGAAGAA
GCGCATGA

Upstream 100 bases:

>100_bases
TCGATGGGTTTTGTGCTGGCGTTGGCGCGCCGCCGGCCGGAGAAGCGCCGGCCGGTGAGCTTCTCCGCTATTTCCGGCAG
GGCCGCGGCTGCGGGCTGAA

Downstream 100 bases:

>100_bases
AAATGCCGCAGACAATCGGAGTGGTGCACTTTGTGGGCATCGGCGGCATCGGCATGAGCGGCATCGCAGAGGTTCTGCAC
ACGCTCGGCTACCATGTGCA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MAGRTILLSAGGTGGHLFPAEALAHELRARGWSVHLATDKRATRFAGTFPADEIHAIDSATFGSRNPLALLKSGLSIWRG
FKQSTALINRLKPAAVVGFGGYPTLPPLYAATRRQVPTLVHEQNAVMGRANKALAPRVTAIAGGFLPESDGPFASKTVLT
GNPVRPAVIQASGTPYAPSSGRGVFRLLVFGGSQGAQYFSQVVPEAVRLLPATLRSRLRIVQQARPEDEGPVRSAYDELG
VKAEVSPFFTDLASRIADAHLVISRSGASTVSEIAVIGRPAILVPYPYALDHDQAANATALERAGGAEIVPQEKLSAERL
RGLLEVAMGAPDKLAAMAAAAKSVGRPDASRLLADVTEAIASGETVTEFKRRRSA

Sequences:

>Translated_375_residues
MAGRTILLSAGGTGGHLFPAEALAHELRARGWSVHLATDKRATRFAGTFPADEIHAIDSATFGSRNPLALLKSGLSIWRG
FKQSTALINRLKPAAVVGFGGYPTLPPLYAATRRQVPTLVHEQNAVMGRANKALAPRVTAIAGGFLPESDGPFASKTVLT
GNPVRPAVIQASGTPYAPSSGRGVFRLLVFGGSQGAQYFSQVVPEAVRLLPATLRSRLRIVQQARPEDEGPVRSAYDELG
VKAEVSPFFTDLASRIADAHLVISRSGASTVSEIAVIGRPAILVPYPYALDHDQAANATALERAGGAEIVPQEKLSAERL
RGLLEVAMGAPDKLAAMAAAAKSVGRPDASRLLADVTEAIASGETVTEFKRRRSA
>Mature_374_residues
AGRTILLSAGGTGGHLFPAEALAHELRARGWSVHLATDKRATRFAGTFPADEIHAIDSATFGSRNPLALLKSGLSIWRGF
KQSTALINRLKPAAVVGFGGYPTLPPLYAATRRQVPTLVHEQNAVMGRANKALAPRVTAIAGGFLPESDGPFASKTVLTG
NPVRPAVIQASGTPYAPSSGRGVFRLLVFGGSQGAQYFSQVVPEAVRLLPATLRSRLRIVQQARPEDEGPVRSAYDELGV
KAEVSPFFTDLASRIADAHLVISRSGASTVSEIAVIGRPAILVPYPYALDHDQAANATALERAGGAEIVPQEKLSAERLR
GLLEVAMGAPDKLAAMAAAAKSVGRPDASRLLADVTEAIASGETVTEFKRRRSA

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=364, Percent_Identity=36.8131868131868, Blast_Score=176, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_MESSB (Q11GS5)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_674565.1
- ProteinModelPortal:   Q11GS5
- SMR:   Q11GS5
- STRING:   Q11GS5
- GeneID:   4182800
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_2007
- NMPDR:   fig|266779.1.peg.602
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q11GS5
- ProtClustDB:   PRK00726
- BioCyc:   MSP266779:MESO_2007-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39465; Mature: 39333

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRTILLSAGGTGGHLFPAEALAHELRARGWSVHLATDKRATRFAGTFPADEIHAIDSA
CCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHCCCCCCHHHHHHCCC
TFGSRNPLALLKSGLSIWRGFKQSTALINRLKPAAVVGFGGYPTLPPLYAATRRQVPTLV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCHHH
HEQNAVMGRANKALAPRVTAIAGGFLPESDGPFASKTVLTGNPVRPAVIQASGTPYAPSS
HHCCHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEECCCCCCCCC
GRGVFRLLVFGGSQGAQYFSQVVPEAVRLLPATLRSRLRIVQQARPEDEGPVRSAYDELG
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHC
VKAEVSPFFTDLASRIADAHLVISRSGASTVSEIAVIGRPAILVPYPYALDHDQAANATA
CCEECHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHH
LERAGGAEIVPQEKLSAERLRGLLEVAMGAPDKLAAMAAAAKSVGRPDASRLLADVTEAI
HHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ASGETVTEFKRRRSA
HCCCHHHHHHHHHCC
>Mature Secondary Structure 
AGRTILLSAGGTGGHLFPAEALAHELRARGWSVHLATDKRATRFAGTFPADEIHAIDSA
CCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHCCCCCCHHHHHHCCC
TFGSRNPLALLKSGLSIWRGFKQSTALINRLKPAAVVGFGGYPTLPPLYAATRRQVPTLV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCHHH
HEQNAVMGRANKALAPRVTAIAGGFLPESDGPFASKTVLTGNPVRPAVIQASGTPYAPSS
HHCCHHHHCCCCCCCCHHHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEECCCCCCCCC
GRGVFRLLVFGGSQGAQYFSQVVPEAVRLLPATLRSRLRIVQQARPEDEGPVRSAYDELG
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHC
VKAEVSPFFTDLASRIADAHLVISRSGASTVSEIAVIGRPAILVPYPYALDHDQAANATA
CCEECHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHH
LERAGGAEIVPQEKLSAERLRGLLEVAMGAPDKLAAMAAAAKSVGRPDASRLLADVTEAI
HHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ASGETVTEFKRRRSA
HCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA