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The map label for this gene is pgsA [H]

Identifier: 110634326

GI number: 110634326

Start: 2118855

End: 2119463

Strand: Direct

Name: pgsA [H]

Synonym: Meso_1976

Alternate gene names: 110634326

Gene position: 2118855-2119463 (Clockwise)

Preceding gene: 110634325

Following gene: 110634327

Centisome position: 48.02

GC content: 57.8

Gene sequence:

>609_bases
ATGAGCCAGCAATCCATGTCGCAACAACGCGCCTTCAACCTTCCAAACCTGCTCACTTATGCGCGCATCATGGCGGTGCC
GCTGATTGTGCTTTGCTTCTTTCTTGAAGGGCGGCTGCAATCCAGCGACTTTGCCCGCTGGTCGGCGCTTGGACTGTTTC
TCGCCGCAAGCGTCACCGATTACCTGGATGGCTATCTCGCGCGAAGCTGGAAGCAAACCTCCAATATCGGCAGAATGCTG
GACCCGATTGCCGACAAGCTGCTCGTGGCAACCTGCCTTCTCCTTCTTGCCGCTGATACGGATCGCACGATCGCAGGCTG
GACGCTCTGGGCCGCGATCGTCATCCTGTGCCGGGAGATCCTGGTATCGGGCTTGAGAGAATATCTTGCCGGGCTGAAGG
TGAGCGTGCCGGTAACACAGCTTGCCAAATGGAAGACAGCCATCCAGATGGTGGCGATCGGCTTCCTCCTCGCCGGCCCT
GCCGGTGACAAGATCGTCCCCTATATAACCGAGACCGGCATCGCGCTTTTGTGGTTTTCCGCGCTCGTGACGCTCTATAC
CGGCTACGATTATTTCCGCGCCGGCTTGAAGCATATCATCGAGGAATAG

Upstream 100 bases:

>100_bases
GGAATCCATAGCCCGGCTGATTTACAATCACTTTCATGAGAGTGGCTAGTGACCAGCCGCTTGACCGCGGTCTACCTGGT
CTGATTTGACTAGGCCGACA

Downstream 100 bases:

>100_bases
CATGAAGCTCATCTATTTCGCATGGGTCCGGGAGCGCATTGGTAAGGAGACCGAGGAGGTTACCTTGCCAGGTGAGGTGA
GGACGGTTGCGGAGCTTCTT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MSQQSMSQQRAFNLPNLLTYARIMAVPLIVLCFFLEGRLQSSDFARWSALGLFLAASVTDYLDGYLARSWKQTSNIGRML
DPIADKLLVATCLLLLAADTDRTIAGWTLWAAIVILCREILVSGLREYLAGLKVSVPVTQLAKWKTAIQMVAIGFLLAGP
AGDKIVPYITETGIALLWFSALVTLYTGYDYFRAGLKHIIEE

Sequences:

>Translated_202_residues
MSQQSMSQQRAFNLPNLLTYARIMAVPLIVLCFFLEGRLQSSDFARWSALGLFLAASVTDYLDGYLARSWKQTSNIGRML
DPIADKLLVATCLLLLAADTDRTIAGWTLWAAIVILCREILVSGLREYLAGLKVSVPVTQLAKWKTAIQMVAIGFLLAGP
AGDKIVPYITETGIALLWFSALVTLYTGYDYFRAGLKHIIEE
>Mature_201_residues
SQQSMSQQRAFNLPNLLTYARIMAVPLIVLCFFLEGRLQSSDFARWSALGLFLAASVTDYLDGYLARSWKQTSNIGRMLD
PIADKLLVATCLLLLAADTDRTIAGWTLWAAIVILCREILVSGLREYLAGLKVSVPVTQLAKWKTAIQMVAIGFLLAGPA
GDKIVPYITETGIALLWFSALVTLYTGYDYFRAGLKHIIEE

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=193, Percent_Identity=37.8238341968912, Blast_Score=119, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320059, Length=175, Percent_Identity=33.1428571428571, Blast_Score=78, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22369; Mature: 22237

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQSMSQQRAFNLPNLLTYARIMAVPLIVLCFFLEGRLQSSDFARWSALGLFLAASVTD
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
YLDGYLARSWKQTSNIGRMLDPIADKLLVATCLLLLAADTDRTIAGWTLWAAIVILCREI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LVSGLREYLAGLKVSVPVTQLAKWKTAIQMVAIGFLLAGPAGDKIVPYITETGIALLWFS
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
ALVTLYTGYDYFRAGLKHIIEE
HHHHHHHCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQQSMSQQRAFNLPNLLTYARIMAVPLIVLCFFLEGRLQSSDFARWSALGLFLAASVTD
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
YLDGYLARSWKQTSNIGRMLDPIADKLLVATCLLLLAADTDRTIAGWTLWAAIVILCREI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LVSGLREYLAGLKVSVPVTQLAKWKTAIQMVAIGFLLAGPAGDKIVPYITETGIALLWFS
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
ALVTLYTGYDYFRAGLKHIIEE
HHHHHHHCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA