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The map label for this gene is iorB [H]

Identifier: 110634257

GI number: 110634257

Start: 2043426

End: 2045675

Strand: Direct

Name: iorB [H]

Synonym: Meso_1907

Alternate gene names: 110634257

Gene position: 2043426-2045675 (Clockwise)

Preceding gene: 110634256

Following gene: 110634258

Centisome position: 46.31

GC content: 65.96

Gene sequence:

>2250_bases
ATGACCATTGTTCCAAAAGACGGCTTCACCCGCAAAGGGCTCACCCGCCGCAGCGTCCTGACCGGCACCGGCGCACTCGT
CGTCAGCTTCGCGCTTGCCCCGCATGTGCTGGCGCAGCAGCAGCCCGCGGCCGCGCCCGAGCCCCCGAAATTGCCCGGCA
GCCTCGATGATGCGCGGCGGCTCGATGCCTGGATCCGCATTGACGCCAATGGCGATATCACGGTGTTCACCGGCAAGATC
GAGCTCGGCCAGGGCATCAAAACGGCGCTCCGGCAAGTGGCTGCGGAAGAACTGGAGGTCGAGCCCGGCGAGATCAACCT
TGTCACCGCCGATACCGGCCGCACGCCGGACGAGGGTTTCACCGCCGGAAGCCAATCGATGCAGAACTCCGGCACGGCGA
TCCGCAACGCCGCGGCCCAGGTTCGCGAGATCCTGATCGCCGAGGCTGCGCGCCGCTGGAACGTGCCGCCTGAAACGCTC
AGGGCCGAGGCCAAGACAATCGTCGCTCAGGACGACCGGACGATCGGCTACGGCGAACTGGTTTCCAGCCAGCTGCTCGC
CGTTGAAGCGCAACCGGAATCTCTTCTCAAGAGTCCGGATGCACTTCGCGTGATCGGCCAGTCCATTCCGCGCGTTGATA
TTCCTGCGAAGGTCACCGGCGGCGTCGCCTATGTCCAGGATCTGCGCCTGGAGGGTATGCTGCATGCACGCGTGGTCCGG
CCGCCGAGCCCTGCCGCGCAGCTGCAGGATGTCGACACCGCCTCGGTCGAACAGATGCCCGGCGTGATCTCGATCGTGCG
CGACGGAAGTTTTCTCGCCGTGGTCGCCGAGCGTGAGTTCGAGGCCGTCAACGCCATGCGCGCCCTCCAGCAGGCGGCGC
GCTGGTCGGAACAGGCCGTTCTGCCAGACCAGAACAACCTGCAGGCGTTCCTGGAGGCCACCAAGGGCGATATCGGGACG
GTGGCCGAGGAGGGTTCGCCGGAGGTCTCCGGCAAGATCTTCGAGGCGACATTCCGGCGCCCCTACCAGATCCATGGCTC
AATCGGGCCTTCCTGCGCCGTCGCGCGCATGGTCGACGGACGGCTTACGGTCTGGTCGCACACCCAGGGCGTCTATCCCG
ATCAGGAAGCGATCGCCGAAATGCTCGGCATGGATCTCGCCAATGTGCGCGTCATCCACATGGAAGGCGCTGGCTGCTAT
GGCCATAACGGCGCCGACGATGCGGCCGCGGATGCAGCCTTGATCGCCTCCGAGGTGCCTGGACGGCCGATCCGGGTGCA
GTGGATGCGTGAAGACGAACATGCCTGGGAGCCGTTCGGTCCGGCGATGCTGATGAAGATCCGCGCCGGCGTCGGCGAGG
ACGGGCGGATCACCGGCTGGAATTACGATCTGTGGAGCAATGTCCACTCCAGTCGCCCCGGCGGTGCCGGCAATCTGCTT
CCAGCGCGCCACCGGGCGCAGGCCTTCTCGGTCCCGGCGCCACGGTTCAACATTAGCCAGTCGGGCAATGGCGATCGCAA
TGCAAATCCGCTCTATGCCTTCCCGAACCGCCGGGTTCTCTGGCATTTCGTGCCGGAAATGCCCCTCAGGGTTTCGGCAC
TGCGCGCCCTGGGCGCCTATGCAAACGTGTTCGCGATAGAGAGCGCGATGGACGAACTCGCACTCCTCGCGGATATGGAC
CCGGTGGAGTTCCGGCTGCGCCACCTGGAAGACGAGCGGGCCCGCGCTGTGGTGGAGAAGGCCGCGGAGGAATTCGGCTG
GTCTTCCGGCGCGCCGAAGGGTGATCGGGGGCGCGGCTTCGCTTTCGCGCGTTACAAGAACTTGGCAGCCTATCTTGCCG
TCGCCGTTGAGCTTGAGCTGGAGCGTGAAACCGGCCGGACGCGCGTGGTGCGGGCGGTCTCCGCGATCGACAGCGGCGAG
GCGGTAAACCCCGACGGCATCCGCAACCAGACGGAGGGCGGCATCATCCAGGCGACAAGCTGGACACTTTACGAGCAGGT
GACCTTCGACGACACGCGCGTCACCAGCACGGACTGGTCGAGCTACCCGATCCTGCGCTTTCCGAGCGCACCGGACAGCG
TGGAGGTGCACGTCGTCAATTCGCCGGGACAACCTTTCCTCGGCACTGGCGAAGCTGCGCAGGGCCCGACACCGGCGGCG
ATCGGCAATGCGCTTCGCCAGCTTACCGGCGTGCGGCTTTACGATCTGCCCTTCACGCGCGAGCGCGTGAAGCAAGCAAT
CGGCGTCTGA

Upstream 100 bases:

>100_bases
TGTGCCGCTGCGGCACGCATATGCGCATCATGGCGGCGATCCGCCGTGCGGGCGAGTTGATGCAGCAAGCGGCTGCCCCG
AGCGAGAGGAGGGCCGGATA

Downstream 100 bases:

>100_bases
CGCGCAGAGCGCGCGGGAGGCGCCGCTCCCTTCTTGGGGGAGAGATACATTGCAATATCGTCTCTGCTAATCGCAATTGT
GAGATTAGCGGAGACGATGC

Product: twin-arginine translocation pathway signal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 749; Mature: 748

Protein sequence:

>749_residues
MTIVPKDGFTRKGLTRRSVLTGTGALVVSFALAPHVLAQQQPAAAPEPPKLPGSLDDARRLDAWIRIDANGDITVFTGKI
ELGQGIKTALRQVAAEELEVEPGEINLVTADTGRTPDEGFTAGSQSMQNSGTAIRNAAAQVREILIAEAARRWNVPPETL
RAEAKTIVAQDDRTIGYGELVSSQLLAVEAQPESLLKSPDALRVIGQSIPRVDIPAKVTGGVAYVQDLRLEGMLHARVVR
PPSPAAQLQDVDTASVEQMPGVISIVRDGSFLAVVAEREFEAVNAMRALQQAARWSEQAVLPDQNNLQAFLEATKGDIGT
VAEEGSPEVSGKIFEATFRRPYQIHGSIGPSCAVARMVDGRLTVWSHTQGVYPDQEAIAEMLGMDLANVRVIHMEGAGCY
GHNGADDAAADAALIASEVPGRPIRVQWMREDEHAWEPFGPAMLMKIRAGVGEDGRITGWNYDLWSNVHSSRPGGAGNLL
PARHRAQAFSVPAPRFNISQSGNGDRNANPLYAFPNRRVLWHFVPEMPLRVSALRALGAYANVFAIESAMDELALLADMD
PVEFRLRHLEDERARAVVEKAAEEFGWSSGAPKGDRGRGFAFARYKNLAAYLAVAVELELERETGRTRVVRAVSAIDSGE
AVNPDGIRNQTEGGIIQATSWTLYEQVTFDDTRVTSTDWSSYPILRFPSAPDSVEVHVVNSPGQPFLGTGEAAQGPTPAA
IGNALRQLTGVRLYDLPFTRERVKQAIGV

Sequences:

>Translated_749_residues
MTIVPKDGFTRKGLTRRSVLTGTGALVVSFALAPHVLAQQQPAAAPEPPKLPGSLDDARRLDAWIRIDANGDITVFTGKI
ELGQGIKTALRQVAAEELEVEPGEINLVTADTGRTPDEGFTAGSQSMQNSGTAIRNAAAQVREILIAEAARRWNVPPETL
RAEAKTIVAQDDRTIGYGELVSSQLLAVEAQPESLLKSPDALRVIGQSIPRVDIPAKVTGGVAYVQDLRLEGMLHARVVR
PPSPAAQLQDVDTASVEQMPGVISIVRDGSFLAVVAEREFEAVNAMRALQQAARWSEQAVLPDQNNLQAFLEATKGDIGT
VAEEGSPEVSGKIFEATFRRPYQIHGSIGPSCAVARMVDGRLTVWSHTQGVYPDQEAIAEMLGMDLANVRVIHMEGAGCY
GHNGADDAAADAALIASEVPGRPIRVQWMREDEHAWEPFGPAMLMKIRAGVGEDGRITGWNYDLWSNVHSSRPGGAGNLL
PARHRAQAFSVPAPRFNISQSGNGDRNANPLYAFPNRRVLWHFVPEMPLRVSALRALGAYANVFAIESAMDELALLADMD
PVEFRLRHLEDERARAVVEKAAEEFGWSSGAPKGDRGRGFAFARYKNLAAYLAVAVELELERETGRTRVVRAVSAIDSGE
AVNPDGIRNQTEGGIIQATSWTLYEQVTFDDTRVTSTDWSSYPILRFPSAPDSVEVHVVNSPGQPFLGTGEAAQGPTPAA
IGNALRQLTGVRLYDLPFTRERVKQAIGV
>Mature_748_residues
TIVPKDGFTRKGLTRRSVLTGTGALVVSFALAPHVLAQQQPAAAPEPPKLPGSLDDARRLDAWIRIDANGDITVFTGKIE
LGQGIKTALRQVAAEELEVEPGEINLVTADTGRTPDEGFTAGSQSMQNSGTAIRNAAAQVREILIAEAARRWNVPPETLR
AEAKTIVAQDDRTIGYGELVSSQLLAVEAQPESLLKSPDALRVIGQSIPRVDIPAKVTGGVAYVQDLRLEGMLHARVVRP
PSPAAQLQDVDTASVEQMPGVISIVRDGSFLAVVAEREFEAVNAMRALQQAARWSEQAVLPDQNNLQAFLEATKGDIGTV
AEEGSPEVSGKIFEATFRRPYQIHGSIGPSCAVARMVDGRLTVWSHTQGVYPDQEAIAEMLGMDLANVRVIHMEGAGCYG
HNGADDAAADAALIASEVPGRPIRVQWMREDEHAWEPFGPAMLMKIRAGVGEDGRITGWNYDLWSNVHSSRPGGAGNLLP
ARHRAQAFSVPAPRFNISQSGNGDRNANPLYAFPNRRVLWHFVPEMPLRVSALRALGAYANVFAIESAMDELALLADMDP
VEFRLRHLEDERARAVVEKAAEEFGWSSGAPKGDRGRGFAFARYKNLAAYLAVAVELELERETGRTRVVRAVSAIDSGEA
VNPDGIRNQTEGGIIQATSWTLYEQVTFDDTRVTSTDWSSYPILRFPSAPDSVEVHVVNSPGQPFLGTGEAAQGPTPAAI
GNALRQLTGVRLYDLPFTRERVKQAIGV

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786478, Length=429, Percent_Identity=23.5431235431235, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 80960; Mature: 80829

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIVPKDGFTRKGLTRRSVLTGTGALVVSFALAPHVLAQQQPAAAPEPPKLPGSLDDARR
CEECCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
LDAWIRIDANGDITVFTGKIELGQGIKTALRQVAAEELEVEPGEINLVTADTGRTPDEGF
CCEEEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
TAGSQSMQNSGTAIRNAAAQVREILIAEAARRWNVPPETLRAEAKTIVAQDDRTIGYGEL
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCCCCHHHH
VSSQLLAVEAQPESLLKSPDALRVIGQSIPRVDIPAKVTGGVAYVQDLRLEGMLHARVVR
HCCCEEEEECCCHHHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEEC
PPSPAAQLQDVDTASVEQMPGVISIVRDGSFLAVVAEREFEAVNAMRALQQAARWSEQAV
CCCCHHHHCCCCHHHHHHCCCEEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCC
LPDQNNLQAFLEATKGDIGTVAEEGSPEVSGKIFEATFRRPYQIHGSIGPSCAVARMVDG
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEHHCCCCEEEECCCCCHHHHHHHHCC
RLTVWSHTQGVYPDQEAIAEMLGMDLANVRVIHMEGAGCYGHNGADDAAADAALIASEVP
EEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCC
GRPIRVQWMREDEHAWEPFGPAMLMKIRAGVGEDGRITGWNYDLWSNVHSSRPGGAGNLL
CCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCEECCCCHHHHCCCCCCCCCCCCCC
PARHRAQAFSVPAPRFNISQSGNGDRNANPLYAFPNRRVLWHFVPEMPLRVSALRALGAY
CCHHHHHEECCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHH
ANVFAIESAMDELALLADMDPVEFRLRHLEDERARAVVEKAAEEFGWSSGAPKGDRGRGF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCE
AFARYKNLAAYLAVAVELELERETGRTRVVRAVSAIDSGEAVNPDGIRNQTEGGIIQATS
EHHHHHHHHHHEEEEEEEEEEHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEC
WTLYEQVTFDDTRVTSTDWSSYPILRFPSAPDSVEVHVVNSPGQPFLGTGEAAQGPTPAA
EEEEEEEECCCCEEECCCCCCCCEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHH
IGNALRQLTGVRLYDLPFTRERVKQAIGV
HHHHHHHHHCCEEEECCCCHHHHHHHHCC
>Mature Secondary Structure 
TIVPKDGFTRKGLTRRSVLTGTGALVVSFALAPHVLAQQQPAAAPEPPKLPGSLDDARR
EECCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
LDAWIRIDANGDITVFTGKIELGQGIKTALRQVAAEELEVEPGEINLVTADTGRTPDEGF
CCEEEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
TAGSQSMQNSGTAIRNAAAQVREILIAEAARRWNVPPETLRAEAKTIVAQDDRTIGYGEL
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCCCCHHHH
VSSQLLAVEAQPESLLKSPDALRVIGQSIPRVDIPAKVTGGVAYVQDLRLEGMLHARVVR
HCCCEEEEECCCHHHHCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEEC
PPSPAAQLQDVDTASVEQMPGVISIVRDGSFLAVVAEREFEAVNAMRALQQAARWSEQAV
CCCCHHHHCCCCHHHHHHCCCEEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCC
LPDQNNLQAFLEATKGDIGTVAEEGSPEVSGKIFEATFRRPYQIHGSIGPSCAVARMVDG
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEHHCCCCEEEECCCCCHHHHHHHHCC
RLTVWSHTQGVYPDQEAIAEMLGMDLANVRVIHMEGAGCYGHNGADDAAADAALIASEVP
EEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCC
GRPIRVQWMREDEHAWEPFGPAMLMKIRAGVGEDGRITGWNYDLWSNVHSSRPGGAGNLL
CCCEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCEECCCCHHHHCCCCCCCCCCCCCC
PARHRAQAFSVPAPRFNISQSGNGDRNANPLYAFPNRRVLWHFVPEMPLRVSALRALGAY
CCHHHHHEECCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHH
ANVFAIESAMDELALLADMDPVEFRLRHLEDERARAVVEKAAEEFGWSSGAPKGDRGRGF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCE
AFARYKNLAAYLAVAVELELERETGRTRVVRAVSAIDSGEAVNPDGIRNQTEGGIIQATS
EHHHHHHHHHHEEEEEEEEEEHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEC
WTLYEQVTFDDTRVTSTDWSSYPILRFPSAPDSVEVHVVNSPGQPFLGTGEAAQGPTPAA
EEEEEEEECCCCEEECCCCCCCCEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHH
IGNALRQLTGVRLYDLPFTRERVKQAIGV
HHHHHHHHHCCEEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]