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The map label for this gene is dgoR [H]

Identifier: 110634217

GI number: 110634217

Start: 2006882

End: 2007619

Strand: Direct

Name: dgoR [H]

Synonym: Meso_1867

Alternate gene names: 110634217

Gene position: 2006882-2007619 (Clockwise)

Preceding gene: 110634210

Following gene: 110634222

Centisome position: 45.48

GC content: 61.92

Gene sequence:

>738_bases
ATGCCGGAGCTTACTCGAAGGCCCTCGCTTTTTTCGCACACGCTCAACCAGCTCGGCCGGCAGATTGTCAGCGGCCGGTT
CGGCGAGAGCGGTGTCATCCCGCCGGAACCGAAACTTTGCGAGCAGCTCGGCGCCAGCCGGGGCGTCGTGCGCGAAGTGC
TGCGTGTGCTCAGCCAAAAAGGCTTGATCTCTGCCCAACCCAAGATCGGCATTCGCGTGGAGCCCGAGCACCACTGGAAC
GTCATGGACATCGACGTCCTCAACTGGCTTTGGGAATTCGGCCCACGGACAAACTACGTCCGGGAATTTCTGGAATTCCG
GCTGATCTTTGAGCCGGCAGCTGCAAGCGCCGCCGCTAAGAATGCGACGGAGGCCGACCGGAGAGAAATACTTGAGCTTT
ACAGGATCCTGGCGGAGGAAAGCGACCGCATATCGGACCGCAGCTCCGACGAGCGTGCGCAGGACGCGGATTTGCAGTTC
CACCTGGCTGTCTTCCGCGCATCCCGAAACAGGCTGCTCGTCTATACGGGAACGCTGATCGGCCACATCATGCGGCAGCA
GATCGCGATGACGACCTCCACTCCCGGCGTGTTCCGCGATGCGGTGCCGCTGCACAAGCAAATGGCAGAGGCGATCGCCA
CGGGAAATCATCGCGAGGCGGAGCGCGCCGCCCGTGACAATGTTATCTGGACGCAAAACGCGCTCGAGAAGCTCAGGGAA
CATCAGGCCGGCGCCTGA

Upstream 100 bases:

>100_bases
CTTATGATATGAGTAGCCTATTTACTCATATGATAAGAGGATTGTGTCAACCGCAAAATTGATATGTAGAGGTTTTCCAC
GCACCTACTCGGAGTCGCGC

Downstream 100 bases:

>100_bases
GCGGCAGCAGCCGAAGTCGATGACGCGCGCGCCGAGCTTTGGGATGCGTGCGAGGCGGTCGATCTTGGCTGCGCCGCACA
CCTGGTTCGACAAGGATGTC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MPELTRRPSLFSHTLNQLGRQIVSGRFGESGVIPPEPKLCEQLGASRGVVREVLRVLSQKGLISAQPKIGIRVEPEHHWN
VMDIDVLNWLWEFGPRTNYVREFLEFRLIFEPAAASAAAKNATEADRREILELYRILAEESDRISDRSSDERAQDADLQF
HLAVFRASRNRLLVYTGTLIGHIMRQQIAMTTSTPGVFRDAVPLHKQMAEAIATGNHREAERAARDNVIWTQNALEKLRE
HQAGA

Sequences:

>Translated_245_residues
MPELTRRPSLFSHTLNQLGRQIVSGRFGESGVIPPEPKLCEQLGASRGVVREVLRVLSQKGLISAQPKIGIRVEPEHHWN
VMDIDVLNWLWEFGPRTNYVREFLEFRLIFEPAAASAAAKNATEADRREILELYRILAEESDRISDRSSDERAQDADLQF
HLAVFRASRNRLLVYTGTLIGHIMRQQIAMTTSTPGVFRDAVPLHKQMAEAIATGNHREAERAARDNVIWTQNALEKLRE
HQAGA
>Mature_244_residues
PELTRRPSLFSHTLNQLGRQIVSGRFGESGVIPPEPKLCEQLGASRGVVREVLRVLSQKGLISAQPKIGIRVEPEHHWNV
MDIDVLNWLWEFGPRTNYVREFLEFRLIFEPAAASAAAKNATEADRREILELYRILAEESDRISDRSSDERAQDADLQFH
LAVFRASRNRLLVYTGTLIGHIMRQQIAMTTSTPGVFRDAVPLHKQMAEAIATGNHREAERAARDNVIWTQNALEKLREH
QAGA

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=214, Percent_Identity=31.7757009345794, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI48994961, Length=209, Percent_Identity=26.7942583732057, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789353, Length=223, Percent_Identity=30.4932735426009, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1790032, Length=231, Percent_Identity=26.4069264069264, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27766; Mature: 27635

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPELTRRPSLFSHTLNQLGRQIVSGRFGESGVIPPEPKLCEQLGASRGVVREVLRVLSQK
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHC
GLISAQPKIGIRVEPEHHWNVMDIDVLNWLWEFGPRTNYVREFLEFRLIFEPAAASAAAK
CCCCCCCCCCEEECCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHC
NATEADRREILELYRILAEESDRISDRSSDERAQDADLQFHLAVFRASRNRLLVYTGTLI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHCCCEEEEEHHHHH
GHIMRQQIAMTTSTPGVFRDAVPLHKQMAEAIATGNHREAERAARDNVIWTQNALEKLRE
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEECHHHHHHHHH
HQAGA
HCCCC
>Mature Secondary Structure 
PELTRRPSLFSHTLNQLGRQIVSGRFGESGVIPPEPKLCEQLGASRGVVREVLRVLSQK
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHC
GLISAQPKIGIRVEPEHHWNVMDIDVLNWLWEFGPRTNYVREFLEFRLIFEPAAASAAAK
CCCCCCCCCCEEECCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHC
NATEADRREILELYRILAEESDRISDRSSDERAQDADLQFHLAVFRASRNRLLVYTGTLI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHCCCEEEEEHHHHH
GHIMRQQIAMTTSTPGVFRDAVPLHKQMAEAIATGNHREAERAARDNVIWTQNALEKLRE
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEECHHHHHHHHH
HQAGA
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]