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The map label for this gene is gsiC [H]

Identifier: 110634206

GI number: 110634206

Start: 1995074

End: 1996087

Strand: Direct

Name: gsiC [H]

Synonym: Meso_1856

Alternate gene names: 110634206

Gene position: 1995074-1996087 (Clockwise)

Preceding gene: 110634205

Following gene: 110634207

Centisome position: 45.21

GC content: 61.05

Gene sequence:

>1014_bases
ATGACGCGCTTTCTCTTCAACCGGCTGATGAGCGGCATCATCGTCGTCATCGGCGTTTCCGTACTGATGTTCCTACTCGC
GCGTGTCATTCCGGGCGACCCGGCGCGCCTTGCACTGGGGCCGGAGGCGAGCGCGGAACAGGTGGAGGCCATGCGCCAGC
AGATGGGCTTCGACCGGCCCATCGCCGAGCAGTACATACGCTTCATGAAGGGTGCGCTGAACTTCGATTTTGGCAGGTCG
CTCTATACCGACAATCCCGTTTCGCAGGACGTTGCCGCCACCTTCCCTGCCACGCTGGAGCTAGTGATCTTCGCTGGCGT
CGCCATGACGTTGATCGGCGGCGCGATGGGAATTGCCAGCGCCCACTTCAAGGACCGCTGGCCGGACAATGCTGCGCGTA
TCCTCTCTTTGCTGGCCGTGGCTCTGCCCAATTTTGTCTGGGCCCTTTTCCTGATGCTGCTTCTTTCCTTCTGGCTCGGT
CTCCTGCCGCTCACGGGCAGGCTGTCGGAAAGCCTGACGGCGCCGCCGGCCGTCACCGGGCTGTACACGGTCGATGCCCT
GTTGGCGGGCCAGTGGCAGGTTTTCCGTGACGCGCTTGCCCATATCGTGCTGCCGGCGGTGGCCCTTTCCCTCCCTGGCC
TGGCGCAGATCTCGCGCCTCACCCGCACCAACATGGTCGATAGCTACGATCGGCCTTTTGTCGAGTTCGCGCGGGCTTAC
GGCTTGGCTGAAAGCTCGATCGCGCTCAAATGGGCGCTGCGGCCGGCCATCATCCCGACCTTGATGATCCTGGGCATGCA
GATCGTCGCGCTGCTCGGCAACGCCTTCATCGTCGAGACGATCTTCCATTGGCCCGGAATGGCGAAATACGGCGTCAATG
CCATTATGCGCAAGGATCTTAACGCGGTGATCGCCGTGGTCATGCTGATTTCGGTCTTCTTCGTGCTGATCAATATGATC
ATCGACACGATCGTCTCCTTTATCGACCCCAAGATCAGGTTGAAGGCCTCATGA

Upstream 100 bases:

>100_bases
ACATTTCGCCTCCAGGTCACCCGGATTGTTTCGAATCAAAGCAGCGCACGATCGAGCCCGGCGCACCCCTGCCCTCCCTA
GTGGAAAAAGGGCCCTCGGT

Downstream 100 bases:

>100_bases
GCAAGGCTGATCCCAGATGGCGCGGATGGCGCCGCTTCGCCCGCAACCGCTTGTCGGTGTTTGGGGCGGCGCTCATCGCG
CTCGTGCTATTTTGCGCCCT

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTRFLFNRLMSGIIVVIGVSVLMFLLARVIPGDPARLALGPEASAEQVEAMRQQMGFDRPIAEQYIRFMKGALNFDFGRS
LYTDNPVSQDVAATFPATLELVIFAGVAMTLIGGAMGIASAHFKDRWPDNAARILSLLAVALPNFVWALFLMLLLSFWLG
LLPLTGRLSESLTAPPAVTGLYTVDALLAGQWQVFRDALAHIVLPAVALSLPGLAQISRLTRTNMVDSYDRPFVEFARAY
GLAESSIALKWALRPAIIPTLMILGMQIVALLGNAFIVETIFHWPGMAKYGVNAIMRKDLNAVIAVVMLISVFFVLINMI
IDTIVSFIDPKIRLKAS

Sequences:

>Translated_337_residues
MTRFLFNRLMSGIIVVIGVSVLMFLLARVIPGDPARLALGPEASAEQVEAMRQQMGFDRPIAEQYIRFMKGALNFDFGRS
LYTDNPVSQDVAATFPATLELVIFAGVAMTLIGGAMGIASAHFKDRWPDNAARILSLLAVALPNFVWALFLMLLLSFWLG
LLPLTGRLSESLTAPPAVTGLYTVDALLAGQWQVFRDALAHIVLPAVALSLPGLAQISRLTRTNMVDSYDRPFVEFARAY
GLAESSIALKWALRPAIIPTLMILGMQIVALLGNAFIVETIFHWPGMAKYGVNAIMRKDLNAVIAVVMLISVFFVLINMI
IDTIVSFIDPKIRLKAS
>Mature_336_residues
TRFLFNRLMSGIIVVIGVSVLMFLLARVIPGDPARLALGPEASAEQVEAMRQQMGFDRPIAEQYIRFMKGALNFDFGRSL
YTDNPVSQDVAATFPATLELVIFAGVAMTLIGGAMGIASAHFKDRWPDNAARILSLLAVALPNFVWALFLMLLLSFWLGL
LPLTGRLSESLTAPPAVTGLYTVDALLAGQWQVFRDALAHIVLPAVALSLPGLAQISRLTRTNMVDSYDRPFVEFARAYG
LAESSIALKWALRPAIIPTLMILGMQIVALLGNAFIVETIFHWPGMAKYGVNAIMRKDLNAVIAVVMLISVFFVLINMII
DTIVSFIDPKIRLKAS

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787761, Length=328, Percent_Identity=38.719512195122, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1787053, Length=335, Percent_Identity=33.7313432835821, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=32.5443786982249, Blast_Score=197, Evalue=8e-52,
Organism=Escherichia coli, GI1789888, Length=337, Percent_Identity=34.1246290801187, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1787550, Length=269, Percent_Identity=30.8550185873606, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1787497, Length=336, Percent_Identity=29.7619047619048, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1788504, Length=304, Percent_Identity=25, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36897; Mature: 36765

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRFLFNRLMSGIIVVIGVSVLMFLLARVIPGDPARLALGPEASAEQVEAMRQQMGFDRP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCC
IAEQYIRFMKGALNFDFGRSLYTDNPVSQDVAATFPATLELVIFAGVAMTLIGGAMGIAS
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHFKDRWPDNAARILSLLAVALPNFVWALFLMLLLSFWLGLLPLTGRLSESLTAPPAVTG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LYTVDALLAGQWQVFRDALAHIVLPAVALSLPGLAQISRLTRTNMVDSYDRPFVEFARAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
GLAESSIALKWALRPAIIPTLMILGMQIVALLGNAFIVETIFHWPGMAKYGVNAIMRKDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
NAVIAVVMLISVFFVLINMIIDTIVSFIDPKIRLKAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure 
TRFLFNRLMSGIIVVIGVSVLMFLLARVIPGDPARLALGPEASAEQVEAMRQQMGFDRP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCCC
IAEQYIRFMKGALNFDFGRSLYTDNPVSQDVAATFPATLELVIFAGVAMTLIGGAMGIAS
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHFKDRWPDNAARILSLLAVALPNFVWALFLMLLLSFWLGLLPLTGRLSESLTAPPAVTG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LYTVDALLAGQWQVFRDALAHIVLPAVALSLPGLAQISRLTRTNMVDSYDRPFVEFARAY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
GLAESSIALKWALRPAIIPTLMILGMQIVALLGNAFIVETIFHWPGMAKYGVNAIMRKDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
NAVIAVVMLISVFFVLINMIIDTIVSFIDPKIRLKAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA