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The map label for this gene is ddpA [H]

Identifier: 110634205

GI number: 110634205

Start: 1993143

End: 1994765

Strand: Direct

Name: ddpA [H]

Synonym: Meso_1855

Alternate gene names: 110634205

Gene position: 1993143-1994765 (Clockwise)

Preceding gene: 110634191

Following gene: 110634206

Centisome position: 45.17

GC content: 60.07

Gene sequence:

>1623_bases
ATGTCGAATTTCATGCTCACGCGCAGGCAACTTCTGGCCGGAACGGCGTCGGCCGGCATAACGTTCGGCGTCGGGCCGAC
GATGCCCTTCGCGGCAGCCGCCGATAAGCGAACGCTGCGTCTGGCCGACGGCAATATCGGTCAGGCCGACCCGCACAAGC
CCGTGGACTTTCCGGGCTCCATCCTCATGTTCAATCTTTACGACTTTCTGGTGCGTCCAGCGCCCGGTGGAGAGATTGAG
CCTTCCGTGGCGGAATCCTGGGAGATTTCGGAGGACGGCAAGGTCTACGCCTTCACCATTCGCGACGGCATCAAGTTCCA
TGACGGTTCGCCGCTGACGGCCGAGGATGTTGTCTTCTCCGCCAACCGCATGATCACGATGAAGCGTGGCTTCTCGTTCC
TCTTGGCCGCTGTCGAGAAAGCCGAGCAGGATGGCAACAAGGTTATCTTCCGGCTGCGCGAGCCGTTTTCACCCTTCCTT
GCAGCGCTGGTGCGCCTTGCTATAGTCAACAAAAAGCTCGTGACGGCCAATCTGAAGGACGGCGAATTCGGGGAGTTCGG
TGACTACGGCGAGGCATTCCTGAGCAGCAACGACGCCGGCAGCGGACCATACAAAATCGCCAGGCATGATTCCCAGAACG
AAACGGTGATGGAGATCAATCCCGATTATTTCGCGGGCTTTGCGCCCAATCCGCCCGAGGTGGTGCGCTCGAAATTCGGC
GTCGAGGCCGTGACCGTGCGCCAGCTCATGCCGCGAGGCGAGATCGACCTTACGCGCCTGCCGCTGCCGCCGGAGATTGT
CGCCGCGCTTTCGCAGTCGGACGGCATTTCTATCGGCCAAGACCGCAAGCCCACCATCTTTCACTTCAAGATGAACACGC
AGAAGGCGCCGCTCGATGACGTGAATGTCAGGAAAGCGATCGCGCTTGCCTTCGACTATGACCAGCTTTACGCGCTTCTT
GATGTGGCCGGCCAGCAGCAGGGTACGCCGATCCGCGGCCCGATCCCGGCGGATGTCATGGGTTATGATCCCGGTGTACC
CCTGATCAAGCGCGATATCGAGGCGGCAAAGGCCGCACTCGCCGAGTCCAAATATGCCGATCAGCCCTTGGAGCTCAATC
TCGTTTGGTTCAAGTCGGTAGCGCTGCAGGAGAAGTTCGCGCTCCTGCTGCAGGCCAATCTGGCCGAGCTCGGAATGAAG
GTGAATATCACCTCCGCCCCGTGGCCTCAGATCGTGGAAATGGCCACCAGTCCCGAAGCGACGCCCCACCTTGCCTGTGT
GGCGACCTCTCTTTCGACAACGGACGTGGACTCCATGCTGTGGGCCGAATATCACAGCTCGGCGGCAGGCACCTATCTTT
CCATGCACTGGCTGCAAAAACCGGAAATCGATGCCGCGCTCGAAAAGGGCCGCCAAACCACCGATCCCGCGGCGCGTCAC
GAGCTTTACAAGGAGCTGGCGCGCGTGATCGCGGACGAGTATCCGTCGGTCTTCCTTTACCAGGCCATCGATCTCGTGGC
ATTCCGGGAAAACCTGCATGTGCCGGGCTTCGAAGACCCGAAGCAGTCCATTCCGATCATGGCCGGCAATTACCGGTACG
ACAGGATGACAATGGATGTTTGA

Upstream 100 bases:

>100_bases
CCCGACGAAGCCATAAAAGGCAGCCGGAAGCGGCGCCCCGCTCCAAGGCGAGACTTGCTTCCTTAATGCCGGCGATTCTA
GCTTGAGAAGGGGAACAGGA

Downstream 100 bases:

>100_bases
CCGGCGACGGGCAGGCATGGAAATCTCCTTGCCTGTTTCGGTCCGGCAAATCCGTTTCGGCGCGGCTCGGCTAGCGCTCC
GGCGAAAGCCGGAGCCACGC

Product: twin-arginine translocation pathway signal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 539

Protein sequence:

>540_residues
MSNFMLTRRQLLAGTASAGITFGVGPTMPFAAAADKRTLRLADGNIGQADPHKPVDFPGSILMFNLYDFLVRPAPGGEIE
PSVAESWEISEDGKVYAFTIRDGIKFHDGSPLTAEDVVFSANRMITMKRGFSFLLAAVEKAEQDGNKVIFRLREPFSPFL
AALVRLAIVNKKLVTANLKDGEFGEFGDYGEAFLSSNDAGSGPYKIARHDSQNETVMEINPDYFAGFAPNPPEVVRSKFG
VEAVTVRQLMPRGEIDLTRLPLPPEIVAALSQSDGISIGQDRKPTIFHFKMNTQKAPLDDVNVRKAIALAFDYDQLYALL
DVAGQQQGTPIRGPIPADVMGYDPGVPLIKRDIEAAKAALAESKYADQPLELNLVWFKSVALQEKFALLLQANLAELGMK
VNITSAPWPQIVEMATSPEATPHLACVATSLSTTDVDSMLWAEYHSSAAGTYLSMHWLQKPEIDAALEKGRQTTDPAARH
ELYKELARVIADEYPSVFLYQAIDLVAFRENLHVPGFEDPKQSIPIMAGNYRYDRMTMDV

Sequences:

>Translated_540_residues
MSNFMLTRRQLLAGTASAGITFGVGPTMPFAAAADKRTLRLADGNIGQADPHKPVDFPGSILMFNLYDFLVRPAPGGEIE
PSVAESWEISEDGKVYAFTIRDGIKFHDGSPLTAEDVVFSANRMITMKRGFSFLLAAVEKAEQDGNKVIFRLREPFSPFL
AALVRLAIVNKKLVTANLKDGEFGEFGDYGEAFLSSNDAGSGPYKIARHDSQNETVMEINPDYFAGFAPNPPEVVRSKFG
VEAVTVRQLMPRGEIDLTRLPLPPEIVAALSQSDGISIGQDRKPTIFHFKMNTQKAPLDDVNVRKAIALAFDYDQLYALL
DVAGQQQGTPIRGPIPADVMGYDPGVPLIKRDIEAAKAALAESKYADQPLELNLVWFKSVALQEKFALLLQANLAELGMK
VNITSAPWPQIVEMATSPEATPHLACVATSLSTTDVDSMLWAEYHSSAAGTYLSMHWLQKPEIDAALEKGRQTTDPAARH
ELYKELARVIADEYPSVFLYQAIDLVAFRENLHVPGFEDPKQSIPIMAGNYRYDRMTMDV
>Mature_539_residues
SNFMLTRRQLLAGTASAGITFGVGPTMPFAAAADKRTLRLADGNIGQADPHKPVDFPGSILMFNLYDFLVRPAPGGEIEP
SVAESWEISEDGKVYAFTIRDGIKFHDGSPLTAEDVVFSANRMITMKRGFSFLLAAVEKAEQDGNKVIFRLREPFSPFLA
ALVRLAIVNKKLVTANLKDGEFGEFGDYGEAFLSSNDAGSGPYKIARHDSQNETVMEINPDYFAGFAPNPPEVVRSKFGV
EAVTVRQLMPRGEIDLTRLPLPPEIVAALSQSDGISIGQDRKPTIFHFKMNTQKAPLDDVNVRKAIALAFDYDQLYALLD
VAGQQQGTPIRGPIPADVMGYDPGVPLIKRDIEAAKAALAESKYADQPLELNLVWFKSVALQEKFALLLQANLAELGMKV
NITSAPWPQIVEMATSPEATPHLACVATSLSTTDVDSMLWAEYHSSAAGTYLSMHWLQKPEIDAALEKGRQTTDPAARHE
LYKELARVIADEYPSVFLYQAIDLVAFRENLHVPGFEDPKQSIPIMAGNYRYDRMTMDV

Specific function: Part of the ABC transporter complex ddpABCDF, which is probably involved in D,D-dipeptide transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787762, Length=494, Percent_Identity=26.9230769230769, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1789966, Length=468, Percent_Identity=27.7777777777778, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1787495, Length=529, Percent_Identity=25.5198487712665, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1787052, Length=512, Percent_Identity=24.21875, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789887, Length=419, Percent_Identity=24.3436754176611, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081878, Length=479, Percent_Identity=21.7118997912317, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789397, Length=87, Percent_Identity=36.7816091954023, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59377; Mature: 59246

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFMLTRRQLLAGTASAGITFGVGPTMPFAAAADKRTLRLADGNIGQADPHKPVDFPGS
CCCCHHHHHHHHHCCCCCCEEECCCCCCCCHHCCCCCEEEEECCCCCCCCCCCCCCCCCH
ILMFNLYDFLVRPAPGGEIEPSVAESWEISEDGKVYAFTIRDGIKFHDGSPLTAEDVVFS
HHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCEEEEEEECCCEECCCCCCCHHHEEEE
ANRMITMKRGFSFLLAAVEKAEQDGNKVIFRLREPFSPFLAALVRLAIVNKKLVTANLKD
CCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCC
GEFGEFGDYGEAFLSSNDAGSGPYKIARHDSQNETVMEINPDYFAGFAPNPPEVVRSKFG
CCCCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCEEEEECCCEEECCCCCCHHHHHHHHC
VEAVTVRQLMPRGEIDLTRLPLPPEIVAALSQSDGISIGQDRKPTIFHFKMNTQKAPLDD
CHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCC
VNVRKAIALAFDYDQLYALLDVAGQQQGTPIRGPIPADVMGYDPGVPLIKRDIEAAKAAL
CCHHEEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AESKYADQPLELNLVWFKSVALQEKFALLLQANLAELGMKVNITSAPWPQIVEMATSPEA
HHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHCCCCC
TPHLACVATSLSTTDVDSMLWAEYHSSAAGTYLSMHWLQKPEIDAALEKGRQTTDPAARH
CCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHCCCCCCCHHHHH
ELYKELARVIADEYPSVFLYQAIDLVAFRENLHVPGFEDPKQSIPIMAGNYRYDRMTMDV
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEECCEEECEEEECC
>Mature Secondary Structure 
SNFMLTRRQLLAGTASAGITFGVGPTMPFAAAADKRTLRLADGNIGQADPHKPVDFPGS
CCCHHHHHHHHHCCCCCCEEECCCCCCCCHHCCCCCEEEEECCCCCCCCCCCCCCCCCH
ILMFNLYDFLVRPAPGGEIEPSVAESWEISEDGKVYAFTIRDGIKFHDGSPLTAEDVVFS
HHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCEEEEEEECCCEECCCCCCCHHHEEEE
ANRMITMKRGFSFLLAAVEKAEQDGNKVIFRLREPFSPFLAALVRLAIVNKKLVTANLKD
CCCEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEEECCC
GEFGEFGDYGEAFLSSNDAGSGPYKIARHDSQNETVMEINPDYFAGFAPNPPEVVRSKFG
CCCCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCEEEEECCCEEECCCCCCHHHHHHHHC
VEAVTVRQLMPRGEIDLTRLPLPPEIVAALSQSDGISIGQDRKPTIFHFKMNTQKAPLDD
CHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCC
VNVRKAIALAFDYDQLYALLDVAGQQQGTPIRGPIPADVMGYDPGVPLIKRDIEAAKAAL
CCHHEEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AESKYADQPLELNLVWFKSVALQEKFALLLQANLAELGMKVNITSAPWPQIVEMATSPEA
HHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHCCCCC
TPHLACVATSLSTTDVDSMLWAEYHSSAAGTYLSMHWLQKPEIDAALEKGRQTTDPAARH
CCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHCCCCCCCHHHHH
ELYKELARVIADEYPSVFLYQAIDLVAFRENLHVPGFEDPKQSIPIMAGNYRYDRMTMDV
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEECCEEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]