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The map label for this gene is qor [H]

Identifier: 110634046

GI number: 110634046

Start: 1811761

End: 1812738

Strand: Reverse

Name: qor [H]

Synonym: Meso_1694

Alternate gene names: 110634046

Gene position: 1812738-1811761 (Counterclockwise)

Preceding gene: 110634047

Following gene: 110634045

Centisome position: 41.08

GC content: 61.96

Gene sequence:

>978_bases
GTGGTGAAAGCGATCCGATTGCGCGAAACCGGCGGGCCGGAGATTCTGAGGCTGGAGGACTATGATCCTGGAAAGCCCGG
GCCCGGCGAGGCCCTGATCGAGCAAAGGGCGATCGGCCTTAATTTTATCGACGTCTACCACCGCACGGGCCTTTACCCGA
CAGCAAAGCCTTTTACGCCCGGCAGTGAGGCTGCGGGTGTCGTCCTGGAGGTGGGCGAGGGCGTGGAGGACCTGAAGCCT
GGCGATCGGGTTGCCTATTGCGTGGCCACTGGCGGCGCCTATGCCGAGCAGCGGCTTGTTCGCGCAGACCGGCTTGTGCG
CGTGCCCGACGCGGTTTCGGACGAGCAGGCGGCAAGTGCTATGCTGAAGGGGCTTACCGCCTGGTACCTCCTGCGGCGAA
CATTTCCGGTAAAGGCAGGCGATACGATCCTTTGCCACGCGGCCGCAGGCGGCGTCGGGCTTGTGCTGGGCCAGTGGGCA
AAGCATCTCGGGGCCAAGGTTATCGGTACGGCCGGTTCACCGGAAAAGGTGGAGCTTGCGAAGGCGCATGGTTACGACCA
TGTGATCGACTACACGAAAGAGGATTTCGTTGCTGCCGTGGGAGAGTTGACCTCAGGCGGCAAATGCGACGTTGTCTATG
ACTCGGTCGGCAAGGATACCTTCCCCGGTTCGCTCGACTGTCTGCGGCCGTTCGGCATGTTCGTCAGCTTCGGCCAATCC
TCGGGCGTCGTGCCGCCGTTCAGCATCAACCTCCTGGCGCAGAAGGGGTCGCTCTTTGCGACACGACCGAGCCTATTCAC
CTATATCGCGGCAAGAAAGGACCTGGAGGAGGGCGCCCAAGAACTCTTCTCCATGATCGAAAGGGGTGCGGTGCAGGTGA
GGGTGAACCAGCGCTATCCTCTTGCCGATGTGGGCAGGGCGCATAAGGATCTGGAAGCGCGGCGCACGACAGGCATGACA
GTACTTATTCCAGGCTGA

Upstream 100 bases:

>100_bases
AGTGGGTGAAGGCCGGGATCGGCGCAACGGGGCTATATCTCTACTGCATAGGGGCCATCATGCAGGCGATCCCCCGGCTT
GGAAGAAAGGGAGTTTGACG

Downstream 100 bases:

>100_bases
ATAGCTTGAAGCACTTTCAACCCGGCGAACTCTATTGCATTGCCAGGAAGCGTGTCTACGATGAACCTGGGAACAAAAAA
ATGAACGGGAGATTTTGTGC

Product: zinc-binding alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MVKAIRLRETGGPEILRLEDYDPGKPGPGEALIEQRAIGLNFIDVYHRTGLYPTAKPFTPGSEAAGVVLEVGEGVEDLKP
GDRVAYCVATGGAYAEQRLVRADRLVRVPDAVSDEQAASAMLKGLTAWYLLRRTFPVKAGDTILCHAAAGGVGLVLGQWA
KHLGAKVIGTAGSPEKVELAKAHGYDHVIDYTKEDFVAAVGELTSGGKCDVVYDSVGKDTFPGSLDCLRPFGMFVSFGQS
SGVVPPFSINLLAQKGSLFATRPSLFTYIAARKDLEEGAQELFSMIERGAVQVRVNQRYPLADVGRAHKDLEARRTTGMT
VLIPG

Sequences:

>Translated_325_residues
MVKAIRLRETGGPEILRLEDYDPGKPGPGEALIEQRAIGLNFIDVYHRTGLYPTAKPFTPGSEAAGVVLEVGEGVEDLKP
GDRVAYCVATGGAYAEQRLVRADRLVRVPDAVSDEQAASAMLKGLTAWYLLRRTFPVKAGDTILCHAAAGGVGLVLGQWA
KHLGAKVIGTAGSPEKVELAKAHGYDHVIDYTKEDFVAAVGELTSGGKCDVVYDSVGKDTFPGSLDCLRPFGMFVSFGQS
SGVVPPFSINLLAQKGSLFATRPSLFTYIAARKDLEEGAQELFSMIERGAVQVRVNQRYPLADVGRAHKDLEARRTTGMT
VLIPG
>Mature_325_residues
MVKAIRLRETGGPEILRLEDYDPGKPGPGEALIEQRAIGLNFIDVYHRTGLYPTAKPFTPGSEAAGVVLEVGEGVEDLKP
GDRVAYCVATGGAYAEQRLVRADRLVRVPDAVSDEQAASAMLKGLTAWYLLRRTFPVKAGDTILCHAAAGGVGLVLGQWA
KHLGAKVIGTAGSPEKVELAKAHGYDHVIDYTKEDFVAAVGELTSGGKCDVVYDSVGKDTFPGSLDCLRPFGMFVSFGQS
SGVVPPFSINLLAQKGSLFATRPSLFTYIAARKDLEEGAQELFSMIERGAVQVRVNQRYPLADVGRAHKDLEARRTTGMT
VLIPG

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=327, Percent_Identity=28.4403669724771, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI13236495, Length=327, Percent_Identity=28.4403669724771, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI18379349, Length=308, Percent_Identity=30.8441558441558, Blast_Score=134, Evalue=9e-32,
Organism=Homo sapiens, GI22538446, Length=336, Percent_Identity=30.952380952381, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI22538444, Length=336, Percent_Identity=30.952380952381, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI194239676, Length=327, Percent_Identity=27.5229357798165, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI24308257, Length=247, Percent_Identity=31.1740890688259, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI28557745, Length=224, Percent_Identity=32.5892857142857, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI47519420, Length=362, Percent_Identity=25.1381215469613, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI156627571, Length=218, Percent_Identity=30.2752293577982, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI197927207, Length=194, Percent_Identity=24.7422680412371, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI226059159, Length=129, Percent_Identity=34.1085271317829, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI226059133, Length=129, Percent_Identity=34.1085271317829, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI226056130, Length=138, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=49.5412844036697, Blast_Score=313, Evalue=1e-86,
Organism=Escherichia coli, GI87081918, Length=322, Percent_Identity=28.8819875776398, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI226510941, Length=296, Percent_Identity=26.0135135135135, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17507255, Length=316, Percent_Identity=27.2151898734177, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17556000, Length=202, Percent_Identity=32.1782178217822, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71988145, Length=354, Percent_Identity=23.1638418079096, Blast_Score=71, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=324, Percent_Identity=37.962962962963, Blast_Score=226, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6323961, Length=270, Percent_Identity=29.6296296296296, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319621, Length=266, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324486, Length=270, Percent_Identity=28.1481481481481, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=253, Percent_Identity=26.4822134387352, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34790; Mature: 34790

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKAIRLRETGGPEILRLEDYDPGKPGPGEALIEQRAIGLNFIDVYHRTGLYPTAKPFTP
CCCEEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCC
GSEAAGVVLEVGEGVEDLKPGDRVAYCVATGGAYAEQRLVRADRLVRVPDAVSDEQAASA
CCCCCEEEEEECCCHHHCCCCCEEEEEEECCCHHHHHHHHHHHHEEECCCCCCHHHHHHH
MLKGLTAWYLLRRTFPVKAGDTILCHAAAGGVGLVLGQWAKHLGAKVIGTAGSPEKVELA
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEH
KAHGYDHVIDYTKEDFVAAVGELTSGGKCDVVYDSVGKDTFPGSLDCLRPFGMFVSFGQS
HHCCCHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHEECCC
SGVVPPFSINLLAQKGSLFATRPSLFTYIAARKDLEEGAQELFSMIERGAVQVRVNQRYP
CCCCCCCEEEEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCC
LADVGRAHKDLEARRTTGMTVLIPG
HHHHHHHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure
MVKAIRLRETGGPEILRLEDYDPGKPGPGEALIEQRAIGLNFIDVYHRTGLYPTAKPFTP
CCCEEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCC
GSEAAGVVLEVGEGVEDLKPGDRVAYCVATGGAYAEQRLVRADRLVRVPDAVSDEQAASA
CCCCCEEEEEECCCHHHCCCCCEEEEEEECCCHHHHHHHHHHHHEEECCCCCCHHHHHHH
MLKGLTAWYLLRRTFPVKAGDTILCHAAAGGVGLVLGQWAKHLGAKVIGTAGSPEKVELA
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEH
KAHGYDHVIDYTKEDFVAAVGELTSGGKCDVVYDSVGKDTFPGSLDCLRPFGMFVSFGQS
HHCCCHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHEECCC
SGVVPPFSINLLAQKGSLFATRPSLFTYIAARKDLEEGAQELFSMIERGAVQVRVNQRYP
CCCCCCCEEEEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCC
LADVGRAHKDLEARRTTGMTVLIPG
HHHHHHHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]