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The map label for this gene is pcs [H]

Identifier: 110634047

GI number: 110634047

Start: 1812741

End: 1813472

Strand: Reverse

Name: pcs [H]

Synonym: Meso_1695

Alternate gene names: 110634047

Gene position: 1813472-1812741 (Counterclockwise)

Preceding gene: 110634050

Following gene: 110634046

Centisome position: 41.1

GC content: 58.2

Gene sequence:

>732_bases
ATGGCGCCGATAAGGAAGAAGAAGGTCACCGCACCGCAGGCGAAAGCCTTTTCGGTCCATCTTCTGACGGCATCCGGTTC
CTTTCTGGCCTTCCTGTCGCTGGTCGCGGCGAGCGAGGGGCGATGGACGGCCATGTTCTGGTGGCTCGGCCTGGCTCTCC
TGGTAGACGGGATCGACGGTCCCATTGCGCGCAAGCTGCAGGTGAAGGATGTGCTGCCCACCTGGTCCGGCGATCTGCTG
GACAATGTCATCGACTATGTCACTTATGTGCTGATTCCCGCCTTTGCGCTTTATCAAAGCGGTTTCATGGGCGCGGGACT
CTCTTTCCTTTCGGCCGCCATCATTGTCATTTCCAGCGCCATCTATTACGCCGATACCGGCATGAAGACGGAGGAGAACT
TCTTTAAGGGTTTCCCGGTCGTCTGGAACATGATCGTATTCACCCTCTTCGTCATCGGACCGGGTGAATACGTCTCGTTC
GGCGTGGTCTTGGTGTCAGCCATTCTTACCTTCGTGCCCGTTCACTTTCTTCATCCCGTACGCGTGGAGCGGCTGAGGGT
TTTGAACCTGGGTGTCTTTCTTGCCTGGTGCGCATTCGGAGCGGTGGCCCTGCTGCAGGACCTGAAGGCGGGTGAGTGGG
TGAAGGCCGGGATCGGCGCAACGGGGCTATATCTCTACTGCATAGGGGCCATCATGCAGGCGATCCCCCGGCTTGGAAGA
AAGGGAGTTTGA

Upstream 100 bases:

>100_bases
AGGAACCGTGGGGGACGATACTGGCGCAGACGACCGGCCGGGCGCATGCTGAGCCCGTTCCTCTCCTCGGCAGGCCTAGA
GCGATCAGAGGCTTTGACTG

Downstream 100 bases:

>100_bases
CGGTGGTGAAAGCGATCCGATTGCGCGAAACCGGCGGGCCGGAGATTCTGAGGCTGGAGGACTATGATCCTGGAAAGCCC
GGGCCCGGCGAGGCCCTGAT

Product: CDP-diacylglycerol-choline O-phosphatidyltransferase

Products: NA

Alternate protein names: PC synthase; CDP-diglyceride-choline O-phosphatidyltransferase [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MAPIRKKKVTAPQAKAFSVHLLTASGSFLAFLSLVAASEGRWTAMFWWLGLALLVDGIDGPIARKLQVKDVLPTWSGDLL
DNVIDYVTYVLIPAFALYQSGFMGAGLSFLSAAIIVISSAIYYADTGMKTEENFFKGFPVVWNMIVFTLFVIGPGEYVSF
GVVLVSAILTFVPVHFLHPVRVERLRVLNLGVFLAWCAFGAVALLQDLKAGEWVKAGIGATGLYLYCIGAIMQAIPRLGR
KGV

Sequences:

>Translated_243_residues
MAPIRKKKVTAPQAKAFSVHLLTASGSFLAFLSLVAASEGRWTAMFWWLGLALLVDGIDGPIARKLQVKDVLPTWSGDLL
DNVIDYVTYVLIPAFALYQSGFMGAGLSFLSAAIIVISSAIYYADTGMKTEENFFKGFPVVWNMIVFTLFVIGPGEYVSF
GVVLVSAILTFVPVHFLHPVRVERLRVLNLGVFLAWCAFGAVALLQDLKAGEWVKAGIGATGLYLYCIGAIMQAIPRLGR
KGV
>Mature_242_residues
APIRKKKVTAPQAKAFSVHLLTASGSFLAFLSLVAASEGRWTAMFWWLGLALLVDGIDGPIARKLQVKDVLPTWSGDLLD
NVIDYVTYVLIPAFALYQSGFMGAGLSFLSAAIIVISSAIYYADTGMKTEENFFKGFPVVWNMIVFTLFVIGPGEYVSFG
VVLVSAILTFVPVHFLHPVRVERLRVLNLGVFLAWCAFGAVALLQDLKAGEWVKAGIGATGLYLYCIGAIMQAIPRLGRK
GV

Specific function: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP [H]

COG id: COG1183

COG function: function code I; Phosphatidylserine synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.24 [H]

Molecular weight: Translated: 26398; Mature: 26266

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCC
>Mature Secondary Structure 
APIRKKKVTAPQAKAFSVHLLTASGSFLAFLSLVAASEGRWTAMFWWLGLALLVDGIDG
CCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
PIARKLQVKDVLPTWSGDLLDNVIDYVTYVLIPAFALYQSGFMGAGLSFLSAAIIVISSA
CHHHHEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
IYYADTGMKTEENFFKGFPVVWNMIVFTLFVIGPGEYVSFGVVLVSAILTFVPVHFLHPV
HHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCHH
RVERLRVLNLGVFLAWCAFGAVALLQDLKAGEWVKAGIGATGLYLYCIGAIMQAIPRLGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCC
KGV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]