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The map label for this gene is ntrY [H]

Identifier: 110633969

GI number: 110633969

Start: 1741179

End: 1743470

Strand: Reverse

Name: ntrY [H]

Synonym: Meso_1617

Alternate gene names: 110633969

Gene position: 1743470-1741179 (Counterclockwise)

Preceding gene: 110633970

Following gene: 110633968

Centisome position: 39.51

GC content: 61.39

Gene sequence:

>2292_bases
ATGAACAGAGGGGCGCCCATAACGGCTGGCAAAGCCTCTTATCAGACAGGCGCATCCAACGACGGTCGCCGCCTGATGGC
GCTGCCCGGCATCATTGCCACGGCAGGGGCACTGGTGACGGCTGCCATCTCCTTTGCCGTGCTGCTTGGCCTTCTTCAGC
CCTACATCACGCCGGATGCGCGTACGACTCTGGTCCTGATCGGCATCAATGCCGCCTTCATTCTCATCCTCCTTGGCCTG
ATTGGTCGCGAAGCACACCGGATCTACGCCGCGCGGCGCGGCGGCAAGGCTGCAGCGCGGCTGCATGTGCGTATCGTCGC
CATGTTCTCGCTGGTGGCGGCGATCCCGGCGATCCTCGTGGCGGTGGTCGCATCTATTACGCTCGATCTTGGCCTTGACC
GCTGGTTCGAGCTCCGGACCCGTGTGATCGTCAATTCGTCGCTGTCGATCGCGGATGCCTATGTGCGCGAGAACGCCGGC
ACGCTGCAGGGTACGACGCTTTCGATGGCGATCGACCTCGACCGCTCCCGCTCGCTCTACAATCTTGACCGCAACGGCTT
CCGGCAATTGCTTACGCAGCAGACAATCGGGCGGGGACTCGCGCAGGCGGCGCTGATCCGCGAGGATGCATCGGCGATTA
TAGCCGCAGACATTCCGGATATGGCAATTCCAACGCCGCGCGAGGGGGCCTTGCGACAGGCAGCCGATGGCCGGCCGGTG
CTTTTCGATCTGCCGCCCGGCAATCTAATCGCGGCCATCGTAAAGCTTCATAATATCCCCGACGCCTATCTCTATACCCT
GCGCGAACTCGATCCGCAGGTCATCAAGGCGCAGCGGCTTGTGGCCGCCAATACAGGGGAATATCGCTCCCTGGAGGCAA
ACCGCTTCAGTACGCAGGTTGCCTTTGCGCTGCTATACCTGATCGTTACGCTTGCCATAGTGCTCGCCGCCATCTGGACG
GGCATAGCCGTGGCCGACCGGATTGTGCGTCCGATCCGGCAGCTTATTGGAGCGGCAGATGCGGTTTCGATGGGCAATCT
GGACGTGGCTGTGCCGGTGCGCGGCTCCGATGGTGACGTTGCCTCCCTTGGCGACACCTTCAACAAGATGACGCTCCAGC
TCAAGACGCAGCGCGACCAGCTCATCTCGGCGCGCGACATGATCGACGAGCGCCGACGCTTCACGGAGGCGGTGCTCTCG
GGCGTCACGGCCGGCGTTATCGGCGTGAACGCCAATGGGACCGTGTCGATCGTCAACCGCTCGGCCGAGACCATGTTAGG
GATCGACGGCGAGAAAACGATCGGGAAGAATCTTTCCGCCGTGCTGCCTCAGTTGGGCGCGGTTTTCGAGACCGGACGCT
CAACCGGCAGGAAAGTGTACCGGGACCAGGTGACCTTCTATCGGCAGGGAGCGGAACGCACCTTCAATATCCAGATCACG
ACGGAGGAGGCGGTCGGTGAAACCCAGCAGCGTTCCTATGTGGTCACCGTGGACGACATTACCGACCTCGTCCAAGCGCA
GCGTTCCACTGCCTGGGCCGACGTGGCGCGACGAATCGCGCATGAGATCAAGAACCCGTTGACGCCGATTCAACTTTCCG
CCGAGCGCATCCGTCGGCGCTTCGGGAAGGTGATTACGGAGGACCGCGCCATTTTCGACCAATGCACGGACACCATTATC
CGGCAGGTCGGTGATATCGGTCGCATGGTGGACGAGTTCTCTGCCTTCGCGCGTATGCCGAAGCCCGAGATGAAGCGACT
GGACCTTCGCGAGCCGCTTCGTGAAGCTTCCTTCCTGATCGAGGTGAGCCGGCCCGACATCAAAATCGAGAACGACCTTG
GCGGCGTGCCGCTGGTGGGGCGTTTTGATACCAGGCTGATGAGTCAGGCTTTTGGCAATGTTATCAAGAACGCGGCGGAA
GCTATTGATGCTGTACCTCAAGAGGAAAGGCGCCCAGGGGCGATCCGGGTTTGCGCGCGCGACATCGGAAATGCAATCGA
GGTGCTTGTGATGGACAACGGCAAGGGCCTGCCGCGAGAAAACCGGCAGAGGCTGCTGGAACCCTACATGACCACGCGCG
AGAAGGGCACAGGGTTGGGACTTGCCATCGTGAAGAAGATTATCGAGGACCACGGCGGCAAGCTGGAGCTTCTCGATGCG
CCGCAGAGCTTTCATGAGGGCGTGGGAGCAATGATTCGGATGGTCTTGCCGGTCACGCAAGCGGATGCGGGGAATGGGGC
AGGGACGGATAATTCGGTAGACAGGACGGAAAAGGTCGACAATGGCGTCTGA

Upstream 100 bases:

>100_bases
GAATTGAGACCACAGCTTTAGGCGCAGCAACAAGCTCGTTGCAAAATCGCCACATTGCGTTGCATATCTGCAACGCAAAG
ACTCTGCAGGTGGGATAGGG

Downstream 100 bases:

>100_bases
CATACTAGTCGTCGACGATGAGGAAGACATTCGCGAATTGGTCGCCGGAATCCTCAGCGACGAAGGACATGAAACCCGAA
CGGCGGGGAATAGCGATGCG

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 763; Mature: 763

Protein sequence:

>763_residues
MNRGAPITAGKASYQTGASNDGRRLMALPGIIATAGALVTAAISFAVLLGLLQPYITPDARTTLVLIGINAAFILILLGL
IGREAHRIYAARRGGKAAARLHVRIVAMFSLVAAIPAILVAVVASITLDLGLDRWFELRTRVIVNSSLSIADAYVRENAG
TLQGTTLSMAIDLDRSRSLYNLDRNGFRQLLTQQTIGRGLAQAALIREDASAIIAADIPDMAIPTPREGALRQAADGRPV
LFDLPPGNLIAAIVKLHNIPDAYLYTLRELDPQVIKAQRLVAANTGEYRSLEANRFSTQVAFALLYLIVTLAIVLAAIWT
GIAVADRIVRPIRQLIGAADAVSMGNLDVAVPVRGSDGDVASLGDTFNKMTLQLKTQRDQLISARDMIDERRRFTEAVLS
GVTAGVIGVNANGTVSIVNRSAETMLGIDGEKTIGKNLSAVLPQLGAVFETGRSTGRKVYRDQVTFYRQGAERTFNIQIT
TEEAVGETQQRSYVVTVDDITDLVQAQRSTAWADVARRIAHEIKNPLTPIQLSAERIRRRFGKVITEDRAIFDQCTDTII
RQVGDIGRMVDEFSAFARMPKPEMKRLDLREPLREASFLIEVSRPDIKIENDLGGVPLVGRFDTRLMSQAFGNVIKNAAE
AIDAVPQEERRPGAIRVCARDIGNAIEVLVMDNGKGLPRENRQRLLEPYMTTREKGTGLGLAIVKKIIEDHGGKLELLDA
PQSFHEGVGAMIRMVLPVTQADAGNGAGTDNSVDRTEKVDNGV

Sequences:

>Translated_763_residues
MNRGAPITAGKASYQTGASNDGRRLMALPGIIATAGALVTAAISFAVLLGLLQPYITPDARTTLVLIGINAAFILILLGL
IGREAHRIYAARRGGKAAARLHVRIVAMFSLVAAIPAILVAVVASITLDLGLDRWFELRTRVIVNSSLSIADAYVRENAG
TLQGTTLSMAIDLDRSRSLYNLDRNGFRQLLTQQTIGRGLAQAALIREDASAIIAADIPDMAIPTPREGALRQAADGRPV
LFDLPPGNLIAAIVKLHNIPDAYLYTLRELDPQVIKAQRLVAANTGEYRSLEANRFSTQVAFALLYLIVTLAIVLAAIWT
GIAVADRIVRPIRQLIGAADAVSMGNLDVAVPVRGSDGDVASLGDTFNKMTLQLKTQRDQLISARDMIDERRRFTEAVLS
GVTAGVIGVNANGTVSIVNRSAETMLGIDGEKTIGKNLSAVLPQLGAVFETGRSTGRKVYRDQVTFYRQGAERTFNIQIT
TEEAVGETQQRSYVVTVDDITDLVQAQRSTAWADVARRIAHEIKNPLTPIQLSAERIRRRFGKVITEDRAIFDQCTDTII
RQVGDIGRMVDEFSAFARMPKPEMKRLDLREPLREASFLIEVSRPDIKIENDLGGVPLVGRFDTRLMSQAFGNVIKNAAE
AIDAVPQEERRPGAIRVCARDIGNAIEVLVMDNGKGLPRENRQRLLEPYMTTREKGTGLGLAIVKKIIEDHGGKLELLDA
PQSFHEGVGAMIRMVLPVTQADAGNGAGTDNSVDRTEKVDNGV
>Mature_763_residues
MNRGAPITAGKASYQTGASNDGRRLMALPGIIATAGALVTAAISFAVLLGLLQPYITPDARTTLVLIGINAAFILILLGL
IGREAHRIYAARRGGKAAARLHVRIVAMFSLVAAIPAILVAVVASITLDLGLDRWFELRTRVIVNSSLSIADAYVRENAG
TLQGTTLSMAIDLDRSRSLYNLDRNGFRQLLTQQTIGRGLAQAALIREDASAIIAADIPDMAIPTPREGALRQAADGRPV
LFDLPPGNLIAAIVKLHNIPDAYLYTLRELDPQVIKAQRLVAANTGEYRSLEANRFSTQVAFALLYLIVTLAIVLAAIWT
GIAVADRIVRPIRQLIGAADAVSMGNLDVAVPVRGSDGDVASLGDTFNKMTLQLKTQRDQLISARDMIDERRRFTEAVLS
GVTAGVIGVNANGTVSIVNRSAETMLGIDGEKTIGKNLSAVLPQLGAVFETGRSTGRKVYRDQVTFYRQGAERTFNIQIT
TEEAVGETQQRSYVVTVDDITDLVQAQRSTAWADVARRIAHEIKNPLTPIQLSAERIRRRFGKVITEDRAIFDQCTDTII
RQVGDIGRMVDEFSAFARMPKPEMKRLDLREPLREASFLIEVSRPDIKIENDLGGVPLVGRFDTRLMSQAFGNVIKNAAE
AIDAVPQEERRPGAIRVCARDIGNAIEVLVMDNGKGLPRENRQRLLEPYMTTREKGTGLGLAIVKKIIEDHGGKLELLDA
PQSFHEGVGAMIRMVLPVTQADAGNGAGTDNSVDRTEKVDNGV

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=373, Percent_Identity=23.5924932975871, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=25.9259259259259, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1790300, Length=345, Percent_Identity=23.4782608695652, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1789808, Length=228, Percent_Identity=28.5087719298246, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82751; Mature: 82751

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRGAPITAGKASYQTGASNDGRRLMALPGIIATAGALVTAAISFAVLLGLLQPYITPDA
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RTTLVLIGINAAFILILLGLIGREAHRIYAARRGGKAAARLHVRIVAMFSLVAAIPAILV
CCEEEEEECHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVVASITLDLGLDRWFELRTRVIVNSSLSIADAYVRENAGTLQGTTLSMAIDLDRSRSLY
HHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHH
NLDRNGFRQLLTQQTIGRGLAQAALIREDASAIIAADIPDMAIPTPREGALRQAADGRPV
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHCCCCCCE
LFDLPPGNLIAAIVKLHNIPDAYLYTLRELDPQVIKAQRLVAANTGEYRSLEANRFSTQV
EEECCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
AFALLYLIVTLAIVLAAIWTGIAVADRIVRPIRQLIGAADAVSMGNLDVAVPVRGSDGDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCH
ASLGDTFNKMTLQLKTQRDQLISARDMIDERRRFTEAVLSGVTAGVIGVNANGTVSIVNR
HHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCEEEECCCCEEEEEEC
SAETMLGIDGEKTIGKNLSAVLPQLGAVFETGRSTGRKVYRDQVTFYRQGAERTFNIQIT
CCHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
TEEAVGETQQRSYVVTVDDITDLVQAQRSTAWADVARRIAHEIKNPLTPIQLSAERIRRR
EHHHHCCHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
FGKVITEDRAIFDQCTDTIIRQVGDIGRMVDEFSAFARMPKPEMKRLDLREPLREASFLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHEEE
EVSRPDIKIENDLGGVPLVGRFDTRLMSQAFGNVIKNAAEAIDAVPQEERRPGAIRVCAR
EECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHH
DIGNAIEVLVMDNGKGLPRENRQRLLEPYMTTREKGTGLGLAIVKKIIEDHGGKLELLDA
HCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEECC
PQSFHEGVGAMIRMVLPVTQADAGNGAGTDNSVDRTEKVDNGV
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MNRGAPITAGKASYQTGASNDGRRLMALPGIIATAGALVTAAISFAVLLGLLQPYITPDA
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RTTLVLIGINAAFILILLGLIGREAHRIYAARRGGKAAARLHVRIVAMFSLVAAIPAILV
CCEEEEEECHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVVASITLDLGLDRWFELRTRVIVNSSLSIADAYVRENAGTLQGTTLSMAIDLDRSRSLY
HHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHH
NLDRNGFRQLLTQQTIGRGLAQAALIREDASAIIAADIPDMAIPTPREGALRQAADGRPV
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHCCCCCCE
LFDLPPGNLIAAIVKLHNIPDAYLYTLRELDPQVIKAQRLVAANTGEYRSLEANRFSTQV
EEECCCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
AFALLYLIVTLAIVLAAIWTGIAVADRIVRPIRQLIGAADAVSMGNLDVAVPVRGSDGDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCH
ASLGDTFNKMTLQLKTQRDQLISARDMIDERRRFTEAVLSGVTAGVIGVNANGTVSIVNR
HHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCEEEECCCCEEEEEEC
SAETMLGIDGEKTIGKNLSAVLPQLGAVFETGRSTGRKVYRDQVTFYRQGAERTFNIQIT
CCHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
TEEAVGETQQRSYVVTVDDITDLVQAQRSTAWADVARRIAHEIKNPLTPIQLSAERIRRR
EHHHHCCHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
FGKVITEDRAIFDQCTDTIIRQVGDIGRMVDEFSAFARMPKPEMKRLDLREPLREASFLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHEEE
EVSRPDIKIENDLGGVPLVGRFDTRLMSQAFGNVIKNAAEAIDAVPQEERRPGAIRVCAR
EECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHH
DIGNAIEVLVMDNGKGLPRENRQRLLEPYMTTREKGTGLGLAIVKKIIEDHGGKLELLDA
HCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEECC
PQSFHEGVGAMIRMVLPVTQADAGNGAGTDNSVDRTEKVDNGV
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]