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The map label for this gene is hflX [H]

Identifier: 110633964

GI number: 110633964

Start: 1735780

End: 1737162

Strand: Reverse

Name: hflX [H]

Synonym: Meso_1612

Alternate gene names: 110633964

Gene position: 1737162-1735780 (Counterclockwise)

Preceding gene: 110633965

Following gene: 110633951

Centisome position: 39.37

GC content: 60.52

Gene sequence:

>1383_bases
TTGGCAGGAAAACCCAAGGCGCACCATGCGGCGGGAGTCGCCCAGGATGGGGCGGGTGCTTCAGCGCGCACCAAGGCTGT
CGTCGTAGCGCCTAGCGTTGCGGCGCGTGCTCGCGCTGCCGTCGAGGATGGTGAGCAGCGGCGGCATATACCACTTTCGC
CTCAGGCCAAACTGGACGAGGCTGTAGGGCTTGCCGAGGCAATCGATCTCGAGATCACCCACAGTGAGTTTTTCACGGTC
GCGCAACCGCGGCCGGCAACGCTGATCGGTGCGGGCAAGGTCAAGGATCTGGCGAATATCGTGGCCGAGACGGGCGCGGA
GCTCGTCATCATTGACCATCAGCTTACCCCGGTTCAGCAACGGAATCTGGAGCGCGAGCTCAAGGCCAAGGTGCTCGACC
GCACCGGTCTGATACTCGAGATTTTCGGACGTCGCGCGCGGACGAAAGAGGGGCGTTTGCAGGTTGACCTCGCTCATCTC
GAATATCAGCGCGGCCGGCTTGTTCGCAGCTGGACCCACCTGGAGCGGCAGCGCGGCGGCGGCGGCTTCATGGGCGGCCC
AGGCGAAACGCAGATCGAGGCGGATCGCCGCCTCCTGCAAGAGCGTATAATCCGCATTAAACGTGAGTTGGAGACCGTCC
GTCGCACTCGTGACCTGCATCGCACCAAGCGGCGCAAGGTGCCTTTTCCCATTGTTGCGATTGTTGGCTACACGAATGCC
GGCAAATCGACGCTCTTCAACAGGCTTACCGGCGCCTCGGTGCTGGCGGAGGATATGCTGTTTGCCACGCTTGATCCGAC
GCTGAGGCGCGTTCGTTTCCCGCACGGGACCGTCGTGATTCTTTCCGATACGGTCGGCTTCATCTCCGACCTTCCGCCGC
ATCTCGTGGCTGCTTTCCGAGCAACGCTCGAAGAAGTGGTGGAAGCGGATGTCATCCTGCACCTGCGCGACATTTCCGAT
CCCGACACGGCGGCCCATGCCAGAGACGTGGAACAGGTGTTGGCGAGTCTCGGCGTGGATACCTCCGATCCGGCCCGTGC
GGTCGAGGTTTGGAACAAAATCGACAGGTTGAGCGAGGCTGATCGCGAGCGATTGTTGCGCGACGATATCAACAAAACGG
CGCCTATCGCCATCTCGGCCATAACGGGTGAGGGAATTGAGGACCTGATGGCTCTTGTCGAGGAGCGTCTTTCAGGCGAG
GTTTCCGAAGTCCTTTTTACCCTTTCTTCCGAACAGATGGGACTGATGGATTGGATTTACCGGCACGCCCGAGTCACGAA
CCGGAAGGACAACGAGGACGGCGGCTCCACAGTGAAAATTCGCGCTACTCAAGCGGCGCGTGAGGAAATTAGCCGGAGAT
TATCTAGGAATAACAAAGGGTAG

Upstream 100 bases:

>100_bases
TGGGCACTCACAGCTTGTCTACAAGCATGCGATCTCCACGATCATGCCCAGCCAGCCGGTGCAGCTGTTCGAGGCGGAGG
AAGGTAGTCGGGAAGGCTGA

Downstream 100 bases:

>100_bases
GGAGGATTATTTAATCTTCTTCGCTTCCTGCCAGTGCGCTTCCATTTCCTCAAGTGAGGCAGCGCCGAGCGCCTTACCTT
CTTCGCGCAAGCGCCGTTCG

Product: GTP-binding protein, HSR1-related

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MAGKPKAHHAAGVAQDGAGASARTKAVVVAPSVAARARAAVEDGEQRRHIPLSPQAKLDEAVGLAEAIDLEITHSEFFTV
AQPRPATLIGAGKVKDLANIVAETGAELVIIDHQLTPVQQRNLERELKAKVLDRTGLILEIFGRRARTKEGRLQVDLAHL
EYQRGRLVRSWTHLERQRGGGGFMGGPGETQIEADRRLLQERIIRIKRELETVRRTRDLHRTKRRKVPFPIVAIVGYTNA
GKSTLFNRLTGASVLAEDMLFATLDPTLRRVRFPHGTVVILSDTVGFISDLPPHLVAAFRATLEEVVEADVILHLRDISD
PDTAAHARDVEQVLASLGVDTSDPARAVEVWNKIDRLSEADRERLLRDDINKTAPIAISAITGEGIEDLMALVEERLSGE
VSEVLFTLSSEQMGLMDWIYRHARVTNRKDNEDGGSTVKIRATQAAREEISRRLSRNNKG

Sequences:

>Translated_460_residues
MAGKPKAHHAAGVAQDGAGASARTKAVVVAPSVAARARAAVEDGEQRRHIPLSPQAKLDEAVGLAEAIDLEITHSEFFTV
AQPRPATLIGAGKVKDLANIVAETGAELVIIDHQLTPVQQRNLERELKAKVLDRTGLILEIFGRRARTKEGRLQVDLAHL
EYQRGRLVRSWTHLERQRGGGGFMGGPGETQIEADRRLLQERIIRIKRELETVRRTRDLHRTKRRKVPFPIVAIVGYTNA
GKSTLFNRLTGASVLAEDMLFATLDPTLRRVRFPHGTVVILSDTVGFISDLPPHLVAAFRATLEEVVEADVILHLRDISD
PDTAAHARDVEQVLASLGVDTSDPARAVEVWNKIDRLSEADRERLLRDDINKTAPIAISAITGEGIEDLMALVEERLSGE
VSEVLFTLSSEQMGLMDWIYRHARVTNRKDNEDGGSTVKIRATQAAREEISRRLSRNNKG
>Mature_459_residues
AGKPKAHHAAGVAQDGAGASARTKAVVVAPSVAARARAAVEDGEQRRHIPLSPQAKLDEAVGLAEAIDLEITHSEFFTVA
QPRPATLIGAGKVKDLANIVAETGAELVIIDHQLTPVQQRNLERELKAKVLDRTGLILEIFGRRARTKEGRLQVDLAHLE
YQRGRLVRSWTHLERQRGGGGFMGGPGETQIEADRRLLQERIIRIKRELETVRRTRDLHRTKRRKVPFPIVAIVGYTNAG
KSTLFNRLTGASVLAEDMLFATLDPTLRRVRFPHGTVVILSDTVGFISDLPPHLVAAFRATLEEVVEADVILHLRDISDP
DTAAHARDVEQVLASLGVDTSDPARAVEVWNKIDRLSEADRERLLRDDINKTAPIAISAITGEGIEDLMALVEERLSGEV
SEVLFTLSSEQMGLMDWIYRHARVTNRKDNEDGGSTVKIRATQAAREEISRRLSRNNKG

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=301, Percent_Identity=34.21926910299, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI310133116, Length=285, Percent_Identity=34.0350877192982, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI310124269, Length=266, Percent_Identity=34.2105263157895, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI310124267, Length=266, Percent_Identity=34.2105263157895, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI310124171, Length=266, Percent_Identity=34.2105263157895, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI310124169, Length=266, Percent_Identity=34.2105263157895, Blast_Score=142, Evalue=7e-34,
Organism=Escherichia coli, GI1790615, Length=359, Percent_Identity=47.075208913649, Blast_Score=298, Evalue=6e-82,
Organism=Caenorhabditis elegans, GI17561038, Length=398, Percent_Identity=32.1608040201005, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24650079, Length=404, Percent_Identity=32.1782178217822, Blast_Score=143, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50753; Mature: 50621

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGKPKAHHAAGVAQDGAGASARTKAVVVAPSVAARARAAVEDGEQRRHIPLSPQAKLDE
CCCCCCCHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCHHHHH
AVGLAEAIDLEITHSEFFTVAQPRPATLIGAGKVKDLANIVAETGAELVIIDHQLTPVQQ
HHCHHHHHEEEEECCCEEEECCCCCCEEEECCHHHHHHHHHHHCCCCEEEEECCCCCHHH
RNLERELKAKVLDRTGLILEIFGRRARTKEGRLQVDLAHLEYQRGRLVRSWTHLERQRGG
HHHHHHHHHHHHHHCCHHHHHHCCHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCC
GGFMGGPGETQIEADRRLLQERIIRIKRELETVRRTRDLHRTKRRKVPFPIVAIVGYTNA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
GKSTLFNRLTGASVLAEDMLFATLDPTLRRVRFPHGTVVILSDTVGFISDLPPHLVAAFR
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEEECCHHHHHCCCHHHHHHHH
ATLEEVVEADVILHLRDISDPDTAAHARDVEQVLASLGVDTSDPARAVEVWNKIDRLSEA
HHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
DRERLLRDDINKTAPIAISAITGEGIEDLMALVEERLSGEVSEVLFTLSSEQMGLMDWIY
HHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHH
RHARVTNRKDNEDGGSTVKIRATQAAREEISRRLSRNNKG
HHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AGKPKAHHAAGVAQDGAGASARTKAVVVAPSVAARARAAVEDGEQRRHIPLSPQAKLDE
CCCCCCHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCHHHHH
AVGLAEAIDLEITHSEFFTVAQPRPATLIGAGKVKDLANIVAETGAELVIIDHQLTPVQQ
HHCHHHHHEEEEECCCEEEECCCCCCEEEECCHHHHHHHHHHHCCCCEEEEECCCCCHHH
RNLERELKAKVLDRTGLILEIFGRRARTKEGRLQVDLAHLEYQRGRLVRSWTHLERQRGG
HHHHHHHHHHHHHHCCHHHHHHCCHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCC
GGFMGGPGETQIEADRRLLQERIIRIKRELETVRRTRDLHRTKRRKVPFPIVAIVGYTNA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
GKSTLFNRLTGASVLAEDMLFATLDPTLRRVRFPHGTVVILSDTVGFISDLPPHLVAAFR
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEEECCHHHHHCCCHHHHHHHH
ATLEEVVEADVILHLRDISDPDTAAHARDVEQVLASLGVDTSDPARAVEVWNKIDRLSEA
HHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
DRERLLRDDINKTAPIAISAITGEGIEDLMALVEERLSGEVSEVLFTLSSEQMGLMDWIY
HHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHH
RHARVTNRKDNEDGGSTVKIRATQAAREEISRRLSRNNKG
HHHHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]