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The map label for this gene is kdgR [H]

Identifier: 110633956

GI number: 110633956

Start: 1727241

End: 1728020

Strand: Direct

Name: kdgR [H]

Synonym: Meso_1604

Alternate gene names: 110633956

Gene position: 1727241-1728020 (Clockwise)

Preceding gene: 110633955

Following gene: 110633957

Centisome position: 39.14

GC content: 57.82

Gene sequence:

>780_bases
ATGACGGTTGGGGGTGTTAAGAAGAGCTCGACCGTCCTCAAGGCGCTGAAGATGCTGGAGGAAATCGGCAATCACGAGGG
CGGGATAGCCTTGTCCGACATCGCCTCCGTCGTAGAACTCGATCGCAGTACGGCCTATCGGCTGCTGACCACCTTGGTCG
ATGCGGGTTTCTTGGTCCGCTCGGAAGAGACGAAAAAGTATGGCCTTACCTACAAACTCATCTCAATAAGTCGTTTCCTG
TTGGCCAATACCGGGCCAGACGACCTCATACGGTCGAAGCTCGCAGAACTTTCAAGGCTAACCCAGGAGGCGGCGAACTT
TTCCGTCCTGGATGGCGATCAAGCGGTCATTCGCCTGCAATCGAAGGGCTCTCATCTCCTCTCGGTAGCGTTCAAGATCG
GCGACAGGTCGGACCTGCATTGCACCTCGATCGGCAAGGTCCTGCTTGCACAGCAGAGCGACCGCTTCATTCAGCGCTTC
CTGTCGCGTCCGTTGCCGAAGGTTACCCCCCAAACACTGACGAATCCGGATGACCTGCTGCGGGAACTCGAAAAAATTCG
CCAGCAAGGCTACGCATTCGACGTCCGGGAATTTGCAGACGATATGTGCTGCGTGGCAGCCCCGCTCTTCGGCGCCCACG
GCAAGCTCTTGGGCGGTATCAATTTCGCCGGTCCGATCACACGCATGAGCCCTGAGCGCATGCGCGAACTCGCCGCGATC
CTCCAGAAGGCCACGAAAGAACTATCCGACGCGATGCGCAGCTCAACCCCAGACGATTAG

Upstream 100 bases:

>100_bases
GATGATTACAATGTGACTGTGCGCTTTTCAAAATCCTGGCGAGCCCGTATTAGTTGCCGAGTGCAGCGTGCACGGTATTT
GCCGGTTCCTGGAGGATCCC

Downstream 100 bases:

>100_bases
TGATTACTATGTGACCGCACCTTTCAAAATGTGCTTTACCTCCTGACTGACTCCCAGTAGGATGATCGGGTCGATGGCTC
ACGCTGTAAACCGTGTCGAA

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MTVGGVKKSSTVLKALKMLEEIGNHEGGIALSDIASVVELDRSTAYRLLTTLVDAGFLVRSEETKKYGLTYKLISISRFL
LANTGPDDLIRSKLAELSRLTQEAANFSVLDGDQAVIRLQSKGSHLLSVAFKIGDRSDLHCTSIGKVLLAQQSDRFIQRF
LSRPLPKVTPQTLTNPDDLLRELEKIRQQGYAFDVREFADDMCCVAAPLFGAHGKLLGGINFAGPITRMSPERMRELAAI
LQKATKELSDAMRSSTPDD

Sequences:

>Translated_259_residues
MTVGGVKKSSTVLKALKMLEEIGNHEGGIALSDIASVVELDRSTAYRLLTTLVDAGFLVRSEETKKYGLTYKLISISRFL
LANTGPDDLIRSKLAELSRLTQEAANFSVLDGDQAVIRLQSKGSHLLSVAFKIGDRSDLHCTSIGKVLLAQQSDRFIQRF
LSRPLPKVTPQTLTNPDDLLRELEKIRQQGYAFDVREFADDMCCVAAPLFGAHGKLLGGINFAGPITRMSPERMRELAAI
LQKATKELSDAMRSSTPDD
>Mature_258_residues
TVGGVKKSSTVLKALKMLEEIGNHEGGIALSDIASVVELDRSTAYRLLTTLVDAGFLVRSEETKKYGLTYKLISISRFLL
ANTGPDDLIRSKLAELSRLTQEAANFSVLDGDQAVIRLQSKGSHLLSVAFKIGDRSDLHCTSIGKVLLAQQSDRFIQRFL
SRPLPKVTPQTLTNPDDLLRELEKIRQQGYAFDVREFADDMCCVAAPLFGAHGKLLGGINFAGPITRMSPERMRELAAIL
QKATKELSDAMRSSTPDD

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=247, Percent_Identity=34.0080971659919, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI87082359, Length=244, Percent_Identity=31.1475409836066, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786468, Length=244, Percent_Identity=28.6885245901639, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789999, Length=256, Percent_Identity=24.21875, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788581, Length=234, Percent_Identity=28.6324786324786, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1786715, Length=247, Percent_Identity=23.0769230769231, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1790752, Length=242, Percent_Identity=25.6198347107438, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28425; Mature: 28294

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVGGVKKSSTVLKALKMLEEIGNHEGGIALSDIASVVELDRSTAYRLLTTLVDAGFLVR
CCCCCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHEE
SEETKKYGLTYKLISISRFLLANTGPDDLIRSKLAELSRLTQEAANFSVLDGDQAVIRLQ
CCCCHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCHHEEEEC
SKGSHLLSVAFKIGDRSDLHCTSIGKVLLAQQSDRFIQRFLSRPLPKVTPQTLTNPDDLL
CCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
RELEKIRQQGYAFDVREFADDMCCVAAPLFGAHGKLLGGINFAGPITRMSPERMRELAAI
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHHHHHHH
LQKATKELSDAMRSSTPDD
HHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TVGGVKKSSTVLKALKMLEEIGNHEGGIALSDIASVVELDRSTAYRLLTTLVDAGFLVR
CCCCCCHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHEE
SEETKKYGLTYKLISISRFLLANTGPDDLIRSKLAELSRLTQEAANFSVLDGDQAVIRLQ
CCCCHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCHHEEEEC
SKGSHLLSVAFKIGDRSDLHCTSIGKVLLAQQSDRFIQRFLSRPLPKVTPQTLTNPDDLL
CCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
RELEKIRQQGYAFDVREFADDMCCVAAPLFGAHGKLLGGINFAGPITRMSPERMRELAAI
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHHHHHHH
LQKATKELSDAMRSSTPDD
HHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]