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The map label for this gene is rpiA [H]

Identifier: 110633812

GI number: 110633812

Start: 1556121

End: 1556828

Strand: Direct

Name: rpiA [H]

Synonym: Meso_1459

Alternate gene names: 110633812

Gene position: 1556121-1556828 (Clockwise)

Preceding gene: 110633810

Following gene: 110633813

Centisome position: 35.27

GC content: 62.57

Gene sequence:

>708_bases
GTGACGGACGCAAAGACGCTTAAGATTGAAGCCGCCAGGGTGGCGCTGGGCTATGTCGAAGATGGCATGAAGCTTGGAAT
CGGCACGGGCTCGACCGCCGAGGAGTTCGTGCGGCTGCTTGCGACGCGCGTTAGCTCGGGGATGAAGATCGTCGGCGTTC
CCACCTCCGAGCGCACGGCTGCCCTTTGCCGCGAGCTGTCGGTTCCCCTTTCGACGCTGGATGAGACGCCGGAACTTGAT
CTGACGGTGGACGGCGCGGACGAAGTGGGGCCGGACCTCACGCTGATCAAGGGCGGCGGCGGTGCGCTGCTTCGCGAGAA
AATCGTTGCCGCGGCTTCACGCCGGATGATCGTGATTGCCGATGAGAGCAAGGTCGTTGATGTGCTTGGCACCTTTCCGC
TGCCCATCGAGGTGAATCCCTTTGGCCTTCGCGCCACCAGGATCGCCATTGAGGCCGCCGCCGCGCGCCTCGGTCTTGCC
GGCGAGATGAGGACACGTATGGCCGGCCAGGAGCCGTTCGTAACGGACGGTGGACATTTCATAATCGATGCATCTTTTGG
CCGTATTCAAGCGCCAAGAGCACTGGCGGAGGCGCTGAATGCAATTCCCGGTGTTGTGGAACACGGTCTCTTCATCGGAC
TGGCTGGCGCGGCGATTATTGCAGGCAGGAACGGTGTCAGGACGCTCGACGCCGGCAGCCGAATCTAG

Upstream 100 bases:

>100_bases
CATTGGCGCCTGCCCGATACGGTGCACCATTCACAGCTGCAAAGCATTTGCGGGAAAAGGTGAAACGGGTTAGGAAGCCG
GTCTGGTTTGGGGCAGGATA

Downstream 100 bases:

>100_bases
ACATGGAGAAGAAGCGAAGATGAAACTGGCCCAACGCGCTCGCATGATCGCATTGACCGCCGCGGTAGCACTGACGGCTC
TGTCATTCCCGGCAGGCGCG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MTDAKTLKIEAARVALGYVEDGMKLGIGTGSTAEEFVRLLATRVSSGMKIVGVPTSERTAALCRELSVPLSTLDETPELD
LTVDGADEVGPDLTLIKGGGGALLREKIVAAASRRMIVIADESKVVDVLGTFPLPIEVNPFGLRATRIAIEAAAARLGLA
GEMRTRMAGQEPFVTDGGHFIIDASFGRIQAPRALAEALNAIPGVVEHGLFIGLAGAAIIAGRNGVRTLDAGSRI

Sequences:

>Translated_235_residues
MTDAKTLKIEAARVALGYVEDGMKLGIGTGSTAEEFVRLLATRVSSGMKIVGVPTSERTAALCRELSVPLSTLDETPELD
LTVDGADEVGPDLTLIKGGGGALLREKIVAAASRRMIVIADESKVVDVLGTFPLPIEVNPFGLRATRIAIEAAAARLGLA
GEMRTRMAGQEPFVTDGGHFIIDASFGRIQAPRALAEALNAIPGVVEHGLFIGLAGAAIIAGRNGVRTLDAGSRI
>Mature_234_residues
TDAKTLKIEAARVALGYVEDGMKLGIGTGSTAEEFVRLLATRVSSGMKIVGVPTSERTAALCRELSVPLSTLDETPELDL
TVDGADEVGPDLTLIKGGGGALLREKIVAAASRRMIVIADESKVVDVLGTFPLPIEVNPFGLRATRIAIEAAAARLGLAG
EMRTRMAGQEPFVTDGGHFIIDASFGRIQAPRALAEALNAIPGVVEHGLFIGLAGAAIIAGRNGVRTLDAGSRI

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=220, Percent_Identity=41.3636363636364, Blast_Score=141, Evalue=6e-34,
Organism=Escherichia coli, GI1789280, Length=224, Percent_Identity=40.625, Blast_Score=137, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17551758, Length=215, Percent_Identity=40.9302325581395, Blast_Score=136, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6324669, Length=242, Percent_Identity=32.6446280991736, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281364072, Length=216, Percent_Identity=37.962962962963, Blast_Score=126, Evalue=1e-29,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 24412; Mature: 24280

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAKTLKIEAARVALGYVEDGMKLGIGTGSTAEEFVRLLATRVSSGMKIVGVPTSERTA
CCCCCEEEEEEHHEEEEECCCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHH
ALCRELSVPLSTLDETPELDLTVDGADEVGPDLTLIKGGGGALLREKIVAAASRRMIVIA
HHHHHHCCCHHHHCCCCCEEEEECCHHHCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEE
DESKVVDVLGTFPLPIEVNPFGLRATRIAIEAAAARLGLAGEMRTRMAGQEPFVTDGGHF
CCCCEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEECCCCE
IIDASFGRIQAPRALAEALNAIPGVVEHGLFIGLAGAAIIAGRNGVRTLDAGSRI
EEECCCCCCCCCHHHHHHHHHCHHHHHCCHHEEECCEEEEECCCCCEECCCCCCC
>Mature Secondary Structure 
TDAKTLKIEAARVALGYVEDGMKLGIGTGSTAEEFVRLLATRVSSGMKIVGVPTSERTA
CCCCEEEEEEHHEEEEECCCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHH
ALCRELSVPLSTLDETPELDLTVDGADEVGPDLTLIKGGGGALLREKIVAAASRRMIVIA
HHHHHHCCCHHHHCCCCCEEEEECCHHHCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEE
DESKVVDVLGTFPLPIEVNPFGLRATRIAIEAAAARLGLAGEMRTRMAGQEPFVTDGGHF
CCCCEEEECCCCCCCEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEECCCCE
IIDASFGRIQAPRALAEALNAIPGVVEHGLFIGLAGAAIIAGRNGVRTLDAGSRI
EEECCCCCCCCCHHHHHHHHHCHHHHHCCHHEEECCEEEEECCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]