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The map label for this gene is lpxA [H]

Identifier: 110633744

GI number: 110633744

Start: 1484734

End: 1485567

Strand: Direct

Name: lpxA [H]

Synonym: Meso_1391

Alternate gene names: 110633744

Gene position: 1484734-1485567 (Clockwise)

Preceding gene: 110633743

Following gene: 110633745

Centisome position: 33.65

GC content: 61.87

Gene sequence:

>834_bases
ATGGCGGAAGCGTTCATCCACCCGACGGCGATAGTCGAAGAAGGGGCCGTACTTGGTGCCGGCGTAAGAATCGGGCCGTT
CTGCCATGTCTCCGCTGAAGCGGTGCTTGGGGATGGGGTGGAGCTGATCGGGCACGTGACTGTTCTTGGCGCGACCACTC
TGGGCGCCGGTTGTCAGGTCTATCCCACAGCCGTGCTGGGCGGAGCGCCGCAGAATTACAAGCATGAGGGCGGCCCAACG
ACGCTTACCGTCGGGCGCGACTGCATCATCCGCGAGGGTGTCACCCTTCATAGGGGCACGGATACGAGCCGCGGCAAGAC
CACCATCGGCGATAATTGCATGTTCATGGCCTACAGCCATGTGGCGCATGATTGCGACGTGGGCAGCAACGTGACCATGG
CGAATTGTGCTTGCCTGGGAGGCCATGTCACGGTCGGCGATGGCGTCATCATTTCCGGTTACGCGGCGGTTCACCAGTTT
GTACGGGTCGGTCACCACGCCTTCCTTGCCGGTTACGCGGCGGTCGTGGGGGATGTCATCCCCTATGGCATGGCAGTGGG
GGACCGGGCCAAATTGCGCGGGCTGAACGTGATCGGCATGAAGCGCAGCGGAATGGCGCGGCCGGACATCATGCAGATCC
GAAAGGCATATCGCCTCCTTTTTTCGGAGGAACAGCCGCTTGCACAGAATATCGAGCGCGTGCGGCAGGAGTTCGGCGGC
TCGGCACTGGTTATGGATATCCTTGACTTCATGGCGGGCCGCGAACGCAAATATTTCGTTCTGCCAGCGCGGGGAGCGTC
CGTGGAAGAGGACGATGAGCACGGAGGCGCATGA

Upstream 100 bases:

>100_bases
ATCTGGAAGTTTGCCTGCGAGGCGATAGTAGACGGCGGAAAGGTTGCGGAGGCCATGATCTCGGCCCTGCTCTCGGCCGA
AGAACCGGAATGACCTGACG

Downstream 100 bases:

>100_bases
GCCGCGCGCGATCGATCTGACGGCGGGAGACCGGATCGCCGTCGTCGCGGGAAGCGGGCTCTTGCCGAGGGAAGTTGCAA
ACGGCCTTGTCCGCGCCGGG

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MAEAFIHPTAIVEEGAVLGAGVRIGPFCHVSAEAVLGDGVELIGHVTVLGATTLGAGCQVYPTAVLGGAPQNYKHEGGPT
TLTVGRDCIIREGVTLHRGTDTSRGKTTIGDNCMFMAYSHVAHDCDVGSNVTMANCACLGGHVTVGDGVIISGYAAVHQF
VRVGHHAFLAGYAAVVGDVIPYGMAVGDRAKLRGLNVIGMKRSGMARPDIMQIRKAYRLLFSEEQPLAQNIERVRQEFGG
SALVMDILDFMAGRERKYFVLPARGASVEEDDEHGGA

Sequences:

>Translated_277_residues
MAEAFIHPTAIVEEGAVLGAGVRIGPFCHVSAEAVLGDGVELIGHVTVLGATTLGAGCQVYPTAVLGGAPQNYKHEGGPT
TLTVGRDCIIREGVTLHRGTDTSRGKTTIGDNCMFMAYSHVAHDCDVGSNVTMANCACLGGHVTVGDGVIISGYAAVHQF
VRVGHHAFLAGYAAVVGDVIPYGMAVGDRAKLRGLNVIGMKRSGMARPDIMQIRKAYRLLFSEEQPLAQNIERVRQEFGG
SALVMDILDFMAGRERKYFVLPARGASVEEDDEHGGA
>Mature_276_residues
AEAFIHPTAIVEEGAVLGAGVRIGPFCHVSAEAVLGDGVELIGHVTVLGATTLGAGCQVYPTAVLGGAPQNYKHEGGPTT
LTVGRDCIIREGVTLHRGTDTSRGKTTIGDNCMFMAYSHVAHDCDVGSNVTMANCACLGGHVTVGDGVIISGYAAVHQFV
RVGHHAFLAGYAAVVGDVIPYGMAVGDRAKLRGLNVIGMKRSGMARPDIMQIRKAYRLLFSEEQPLAQNIERVRQEFGGS
ALVMDILDFMAGRERKYFVLPARGASVEEDDEHGGA

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=253, Percent_Identity=41.501976284585, Blast_Score=188, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 29193; Mature: 29062

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00296 CHAPERONINS_CPN60

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEAFIHPTAIVEEGAVLGAGVRIGPFCHVSAEAVLGDGVELIGHVTVLGATTLGAGCQV
CCCCCCCCHHHHHCCCEEECCCEECCEEEECHHHHHCCCHHHHHHHHEEEHHHCCCCCEE
YPTAVLGGAPQNYKHEGGPTTLTVGRDCIIREGVTLHRGTDTSRGKTTIGDNCMFMAYSH
ECHHHCCCCCCCCCCCCCCEEEEECCCEEEECCEEEECCCCCCCCCCEECCCEEEEEHHH
VAHDCDVGSNVTMANCACLGGHVTVGDGVIISGYAAVHQFVRVGHHAFLAGYAAVVGDVI
HHHCCCCCCCCEEEHEEEECCEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
PYGMAVGDRAKLRGLNVIGMKRSGMARPDIMQIRKAYRLLFSEEQPLAQNIERVRQEFGG
HHCCCCCCCHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
SALVMDILDFMAGRERKYFVLPARGASVEEDDEHGGA
CCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
AEAFIHPTAIVEEGAVLGAGVRIGPFCHVSAEAVLGDGVELIGHVTVLGATTLGAGCQV
CCCCCCCHHHHHCCCEEECCCEECCEEEECHHHHHCCCHHHHHHHHEEEHHHCCCCCEE
YPTAVLGGAPQNYKHEGGPTTLTVGRDCIIREGVTLHRGTDTSRGKTTIGDNCMFMAYSH
ECHHHCCCCCCCCCCCCCCEEEEECCCEEEECCEEEECCCCCCCCCCEECCCEEEEEHHH
VAHDCDVGSNVTMANCACLGGHVTVGDGVIISGYAAVHQFVRVGHHAFLAGYAAVVGDVI
HHHCCCCCCCCEEEHEEEECCEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
PYGMAVGDRAKLRGLNVIGMKRSGMARPDIMQIRKAYRLLFSEEQPLAQNIERVRQEFGG
HHCCCCCCCHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
SALVMDILDFMAGRERKYFVLPARGASVEEDDEHGGA
CCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]