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The map label for this gene is fabZ

Identifier: 110633743

GI number: 110633743

Start: 1484256

End: 1484726

Strand: Direct

Name: fabZ

Synonym: Meso_1390

Alternate gene names: 110633743

Gene position: 1484256-1484726 (Clockwise)

Preceding gene: 110633742

Following gene: 110633744

Centisome position: 33.64

GC content: 56.48

Gene sequence:

>471_bases
ATGGCCGACGGTGTGTCGCCCGCGATGGAAAGCCTCGACATTTTGAACGTGCTGCGACTCCTGCCGCACCGCTATCCATT
TCTGCTGGTGGACAGGATTGTAGAAATAGATGGCGACAACTCAGCCATCGGCATCAAGAATGTCACGGTGAACGAGCCCC
ACTTCATGGGGCATTTCCCGGAGCGTCCGGTCATGCCGGGGGTGCTGATCATCGAGGCTATGGCCCAGACCGCAGGAGCC
ATCTGCATTCAGCATGCAAAGCAAATAAAGCCGTCGGTCGTCTATTTTCTGACAATTGAGAATGCGAAGTTTCGCAAGCC
CGTGGTGCCGGGCGACAGAATGGAAATCCATGTGAAGAAGGTGAAGCAGCGCGGCATGATCTGGAAGTTTGCCTGCGAGG
CGATAGTAGACGGCGGAAAGGTTGCGGAGGCCATGATCTCGGCCCTGCTCTCGGCCGAAGAACCGGAATGA

Upstream 100 bases:

>100_bases
GATGGGCCGGCGTGCCGGCCAAGCCCATGCGGCAGGCGTTCCGCGAAATCGCGGCGCTGCGCAGCCTGGTGCAGGATATG
CGGAAGGGGAGTAAGGGATA

Downstream 100 bases:

>100_bases
CCTGACGATGGCGGAAGCGTTCATCCACCCGACGGCGATAGTCGAAGAAGGGGCCGTACTTGGTGCCGGCGTAAGAATCG
GGCCGTTCTGCCATGTCTCC

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MADGVSPAMESLDILNVLRLLPHRYPFLLVDRIVEIDGDNSAIGIKNVTVNEPHFMGHFPERPVMPGVLIIEAMAQTAGA
ICIQHAKQIKPSVVYFLTIENAKFRKPVVPGDRMEIHVKKVKQRGMIWKFACEAIVDGGKVAEAMISALLSAEEPE

Sequences:

>Translated_156_residues
MADGVSPAMESLDILNVLRLLPHRYPFLLVDRIVEIDGDNSAIGIKNVTVNEPHFMGHFPERPVMPGVLIIEAMAQTAGA
ICIQHAKQIKPSVVYFLTIENAKFRKPVVPGDRMEIHVKKVKQRGMIWKFACEAIVDGGKVAEAMISALLSAEEPE
>Mature_155_residues
ADGVSPAMESLDILNVLRLLPHRYPFLLVDRIVEIDGDNSAIGIKNVTVNEPHFMGHFPERPVMPGVLIIEAMAQTAGAI
CIQHAKQIKPSVVYFLTIENAKFRKPVVPGDRMEIHVKKVKQRGMIWKFACEAIVDGGKVAEAMISALLSAEEPE

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=144, Percent_Identity=45.1388888888889, Blast_Score=132, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_MESSB (Q11II9)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_673951.1
- ProteinModelPortal:   Q11II9
- SMR:   Q11II9
- STRING:   Q11II9
- GeneID:   4181237
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_1390
- NMPDR:   fig|266779.1.peg.2202
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   NVSANES
- PhylomeDB:   Q11II9
- ProtClustDB:   PRK00006
- BioCyc:   MSP266779:MESO_1390-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 17228; Mature: 17096

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: ACT_SITE 58-58

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADGVSPAMESLDILNVLRLLPHRYPFLLVDRIVEIDGDNSAIGIKNVTVNEPHFMGHFP
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCC
ERPVMPGVLIIEAMAQTAGAICIQHAKQIKPSVVYFLTIENAKFRKPVVPGDRMEIHVKK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHH
VKQRGMIWKFACEAIVDGGKVAEAMISALLSAEEPE
HHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ADGVSPAMESLDILNVLRLLPHRYPFLLVDRIVEIDGDNSAIGIKNVTVNEPHFMGHFP
CCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCC
ERPVMPGVLIIEAMAQTAGAICIQHAKQIKPSVVYFLTIENAKFRKPVVPGDRMEIHVKK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHH
VKQRGMIWKFACEAIVDGGKVAEAMISALLSAEEPE
HHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA