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The map label for this gene is tsf

Identifier: 110633735

GI number: 110633735

Start: 1475309

End: 1476232

Strand: Direct

Name: tsf

Synonym: Meso_1382

Alternate gene names: 110633735

Gene position: 1475309-1476232 (Clockwise)

Preceding gene: 110633734

Following gene: 110633736

Centisome position: 33.44

GC content: 61.9

Gene sequence:

>924_bases
ATGAGCATTTCAGCTGCACTGGTCAAGCAACTGCGCGAAGTGACGGGCGCAGGCATGATGGACTGCAAGACCGCGCTTGC
TGAGACTGGCGGCGATCTTGAGGCTGCGGTCGACTGGCTGCGCAAGAAGGGCATTTCCAAGGCGGACAAGAAGGCCGGCC
GCACGGCGGCCGAGGGCCTTATCGGCCTTGCCGCGGATGCCACGAGCGCCGTGGCCGTCGAGGTCAACTCCGAAACCGAT
TTCGTGGCACGCAACGATGCGTTCCAGGAGTTGGTGCGCAATATTGCTCAGGTCGCATTGGGAACCGACGGCAATGTCGA
GGCTGTTTCCGCGGCCTCGTATCCCGGCAGCGGAAAGTCCGTGGCGGATGCAGTTCGCGATGCCATCGCAACCATCGGCG
AAAATATGGCGCTGCGCCGCTCCGCGAAGCTTTCGGTCAGCAAGGGCGCGGTTGCGACCTATGTGCACAACTCCGTGAGC
GAAGGCCTTGGCAAGATCGGTGTTCTCGTTGCGATCGAGACCGAGGGCAACGCCGAGGCGGCCCGCAATTTCGGGCGCCA
GGTGGCAATGCACGTTGCCGCGACCAACCCGCTTGCCCTGTCGGAGGCGGAGGTGGATCCGGCTGCCGTCGCCCGTGAGA
AGGAGATTTTCTCCGATCAGGCCCGTCAGTCCGGAAAGCCCGAAAACATCATCGAGAAGATGGTCGAGGGCCGGCTGCGC
AAATTCTATGAGGAAGTTGTGCTCGTGAAGCAGGCTTTCGTCATAAATCCGGACCTGACGATCGAGAAGGCGCTCAAAGA
AGCGGAGAAGGAGATCGGTGCCCCGGCAAAGATCACCGGCTTCATCCGCTTCGCGCTTGGCGAGGGTGTCGAGCGTGAAA
GCTCGGATTTCGCCGCTGAGGTCGCGGCCGCAGCCAAGAAGTAA

Upstream 100 bases:

>100_bases
CGGGTAGCCAAGCATAGAAAGGGTTTCTGTAGGAGACCCCTCTACCCTATTTTCCGGGTCGCCTTTCATGGCGACCCACA
TGAATTAAAGAGAGGCGACG

Downstream 100 bases:

>100_bases
ACACCGCAATTGAGCTTCAATCGAGGGCACCGCGTGACAACGCGGTGCCCTTCGTGTAGGGCCACTTGTCTGAAGCATCG
AAACGGCTCTAATCGTCTAA

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSISAALVKQLREVTGAGMMDCKTALAETGGDLEAAVDWLRKKGISKADKKAGRTAAEGLIGLAADATSAVAVEVNSETD
FVARNDAFQELVRNIAQVALGTDGNVEAVSAASYPGSGKSVADAVRDAIATIGENMALRRSAKLSVSKGAVATYVHNSVS
EGLGKIGVLVAIETEGNAEAARNFGRQVAMHVAATNPLALSEAEVDPAAVAREKEIFSDQARQSGKPENIIEKMVEGRLR
KFYEEVVLVKQAFVINPDLTIEKALKEAEKEIGAPAKITGFIRFALGEGVERESSDFAAEVAAAAKK

Sequences:

>Translated_307_residues
MSISAALVKQLREVTGAGMMDCKTALAETGGDLEAAVDWLRKKGISKADKKAGRTAAEGLIGLAADATSAVAVEVNSETD
FVARNDAFQELVRNIAQVALGTDGNVEAVSAASYPGSGKSVADAVRDAIATIGENMALRRSAKLSVSKGAVATYVHNSVS
EGLGKIGVLVAIETEGNAEAARNFGRQVAMHVAATNPLALSEAEVDPAAVAREKEIFSDQARQSGKPENIIEKMVEGRLR
KFYEEVVLVKQAFVINPDLTIEKALKEAEKEIGAPAKITGFIRFALGEGVERESSDFAAEVAAAAKK
>Mature_306_residues
SISAALVKQLREVTGAGMMDCKTALAETGGDLEAAVDWLRKKGISKADKKAGRTAAEGLIGLAADATSAVAVEVNSETDF
VARNDAFQELVRNIAQVALGTDGNVEAVSAASYPGSGKSVADAVRDAIATIGENMALRRSAKLSVSKGAVATYVHNSVSE
GLGKIGVLVAIETEGNAEAARNFGRQVAMHVAATNPLALSEAEVDPAAVAREKEIFSDQARQSGKPENIIEKMVEGRLRK
FYEEVVLVKQAFVINPDLTIEKALKEAEKEIGAPAKITGFIRFALGEGVERESSDFAAEVAAAAKK

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=242, Percent_Identity=36.7768595041322, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI291084500, Length=263, Percent_Identity=33.8403041825095, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI291084498, Length=110, Percent_Identity=48.1818181818182, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI291084502, Length=110, Percent_Identity=48.1818181818182, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI1786366, Length=305, Percent_Identity=42.2950819672131, Blast_Score=206, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17561440, Length=299, Percent_Identity=26.0869565217391, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI19921466, Length=307, Percent_Identity=26.3843648208469, Blast_Score=95, Evalue=6e-20,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_MESSB (Q11IJ7)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_673943.1
- ProteinModelPortal:   Q11IJ7
- SMR:   Q11IJ7
- STRING:   Q11IJ7
- GeneID:   4181229
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_1382
- NMPDR:   fig|266779.1.peg.2210
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- PhylomeDB:   Q11IJ7
- ProtClustDB:   PRK09377
- BioCyc:   MSP266779:MESO_1382-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 32145; Mature: 32014

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISAALVKQLREVTGAGMMDCKTALAETGGDLEAAVDWLRKKGISKADKKAGRTAAEGL
CCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCHHHHHH
IGLAADATSAVAVEVNSETDFVARNDAFQELVRNIAQVALGTDGNVEAVSAASYPGSGKS
HHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHH
VADAVRDAIATIGENMALRRSAKLSVSKGAVATYVHNSVSEGLGKIGVLVAIETEGNAEA
HHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCHHH
ARNFGRQVAMHVAATNPLALSEAEVDPAAVAREKEIFSDQARQSGKPENIIEKMVEGRLR
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KFYEEVVLVKQAFVINPDLTIEKALKEAEKEIGAPAKITGFIRFALGEGVERESSDFAAE
HHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHH
VAAAAKK
HHHHHCC
>Mature Secondary Structure 
SISAALVKQLREVTGAGMMDCKTALAETGGDLEAAVDWLRKKGISKADKKAGRTAAEGL
CCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCHHHHHH
IGLAADATSAVAVEVNSETDFVARNDAFQELVRNIAQVALGTDGNVEAVSAASYPGSGKS
HHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHH
VADAVRDAIATIGENMALRRSAKLSVSKGAVATYVHNSVSEGLGKIGVLVAIETEGNAEA
HHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCHHH
ARNFGRQVAMHVAATNPLALSEAEVDPAAVAREKEIFSDQARQSGKPENIIEKMVEGRLR
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KFYEEVVLVKQAFVINPDLTIEKALKEAEKEIGAPAKITGFIRFALGEGVERESSDFAAE
HHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHH
VAAAAKK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA