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The map label for this gene is sdaA [H]

Identifier: 110633720

GI number: 110633720

Start: 1459943

End: 1461343

Strand: Direct

Name: sdaA [H]

Synonym: Meso_1367

Alternate gene names: 110633720

Gene position: 1459943-1461343 (Clockwise)

Preceding gene: 110633719

Following gene: 110633721

Centisome position: 33.09

GC content: 63.67

Gene sequence:

>1401_bases
ATGTTCCTTTCAGTCTTCGATCTTTTCAAGATCGGCATCGGTCCGTCGAGTTCACATACGATGGGGCCGATGGTAGCCGC
AGAGCGCTTTCTGCGCGAAATCGCGGAAGGGGAGTGGCCGCGGCCGGCGGGCGTGCAAGTCAATCGGCTGTCCGTCAGCC
TGCACGGCTCGCTCGCATTCACGGGTGTGGGACACGCTACCGACCGCGCCGCGATCCTTGGGCTGCAAGGTTTCACACCG
ACGACGGTGGACCCGGACCAGGCGGATTCCATTCTGGAACAAATCGGCAGCACAAAGCGGCTTTCGCCCGCCGGACATCC
CGAATACCGCTTCGACCCCGAGACGGATCTCGTCTTTGACAGGAAGGCGCCTCTGCCCGGCCATGCGAATGGAATGGCGT
TCAGCGCTTTCGATGCGGATGATCGGCTGCTTTTGCGACGCGTCTATTACTCCGTGGGCGGCGGGTTCGTAGTCTCGCAG
GAGGAGCTTGAAGCGCTGAAGGCCGAGAAGAGGCCGGGCGCGGATAGCAGCGTCCCCTATCCCTTTACCAATGCCCGCCA
GATGCTGGAGATGGCCGCCTCAAGCGGCCTCTCGATCGCCGAGATGAAGCGTGCCAACGAGCTGGCTCACAGAAGCGCTC
AGGAACTTGACGCGGGCCTCGATCGCATTTGGGACGCCATGCATGGCTGCATCGAGCGCGGGCTGACGCAGGAAGGCATC
ATGCCGGGCGGGCTGAAAGTGCGCCGCCGCGCGCGTGAACTGCACCGCAAGCTGGAAGAGGAATGGCGGCAGAACAGGCC
CAACCCCCTTGCCGCCAATGACTGGCTTTCCGTTTATGCCATGGCCGTCAATGAAGAGAACGCGGCGGGCGGAAGGGTCG
TCACCGCTCCCACCAACGGCGCGGCGGGCGTCGTGCCGGCGGTGATGCGCTACTGGCTGCGGTTCCATCCCGAGGCAGAC
AGGAACGGCATTCGCGATTTCCTGCTCACTGCCGCGGCGATTGGCGGACTCATCAAATTCAATGCGTCGATTTCCGGCGC
GGAGGTGGGCTGCCAGGGGGAAGTGGGCTCCGCCTCGGCCATGGCGGCGGCGGGGCTGGCCGCGGTCATGGGCGGCACGC
CCGAGCAAGTGGAAAACGCGGCCGAGATCGCGTTGGAACACCATCTTGGCATGACCTGCGACCCGGTGGCCGGTCTCGTG
CAAGTGCCCTGCATCGAGCGTAATGCGCTGGGTGCGGTCAAGGCTGTTACGGCGGCATCTCTGGCCATCAAAGGCGACGG
CCAGCATTTCGTATCGCTGGACGCCGCGGTCGAGACCATGCGCCAGACGGGGCTCGATATGAACGAGCGCTATAAGGAAA
CAAGTCTCGGCGGGCTTGCGGTCAATGTAGTAGAATGCTGA

Upstream 100 bases:

>100_bases
GGCCTGCGCCCCGTTTTCTTTTGGACCTTGCGTTGCCATGCCGGCATAGGCATATCCGCCTTGTTCGTGCGATGAGCAAA
CAGGCTCGCTGGAGTCCGCC

Downstream 100 bases:

>100_bases
CCGCCTGTGGAAAGGGCGGGGCCGCGTTGACCTTGCCTCTGATATTCCCGATGGTGCGGCCATGGCCCTTTATCTCATAA
AATTGTGCGTTGGTTGCGAA

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MFLSVFDLFKIGIGPSSSHTMGPMVAAERFLREIAEGEWPRPAGVQVNRLSVSLHGSLAFTGVGHATDRAAILGLQGFTP
TTVDPDQADSILEQIGSTKRLSPAGHPEYRFDPETDLVFDRKAPLPGHANGMAFSAFDADDRLLLRRVYYSVGGGFVVSQ
EELEALKAEKRPGADSSVPYPFTNARQMLEMAASSGLSIAEMKRANELAHRSAQELDAGLDRIWDAMHGCIERGLTQEGI
MPGGLKVRRRARELHRKLEEEWRQNRPNPLAANDWLSVYAMAVNEENAAGGRVVTAPTNGAAGVVPAVMRYWLRFHPEAD
RNGIRDFLLTAAAIGGLIKFNASISGAEVGCQGEVGSASAMAAAGLAAVMGGTPEQVENAAEIALEHHLGMTCDPVAGLV
QVPCIERNALGAVKAVTAASLAIKGDGQHFVSLDAAVETMRQTGLDMNERYKETSLGGLAVNVVEC

Sequences:

>Translated_466_residues
MFLSVFDLFKIGIGPSSSHTMGPMVAAERFLREIAEGEWPRPAGVQVNRLSVSLHGSLAFTGVGHATDRAAILGLQGFTP
TTVDPDQADSILEQIGSTKRLSPAGHPEYRFDPETDLVFDRKAPLPGHANGMAFSAFDADDRLLLRRVYYSVGGGFVVSQ
EELEALKAEKRPGADSSVPYPFTNARQMLEMAASSGLSIAEMKRANELAHRSAQELDAGLDRIWDAMHGCIERGLTQEGI
MPGGLKVRRRARELHRKLEEEWRQNRPNPLAANDWLSVYAMAVNEENAAGGRVVTAPTNGAAGVVPAVMRYWLRFHPEAD
RNGIRDFLLTAAAIGGLIKFNASISGAEVGCQGEVGSASAMAAAGLAAVMGGTPEQVENAAEIALEHHLGMTCDPVAGLV
QVPCIERNALGAVKAVTAASLAIKGDGQHFVSLDAAVETMRQTGLDMNERYKETSLGGLAVNVVEC
>Mature_466_residues
MFLSVFDLFKIGIGPSSSHTMGPMVAAERFLREIAEGEWPRPAGVQVNRLSVSLHGSLAFTGVGHATDRAAILGLQGFTP
TTVDPDQADSILEQIGSTKRLSPAGHPEYRFDPETDLVFDRKAPLPGHANGMAFSAFDADDRLLLRRVYYSVGGGFVVSQ
EELEALKAEKRPGADSSVPYPFTNARQMLEMAASSGLSIAEMKRANELAHRSAQELDAGLDRIWDAMHGCIERGLTQEGI
MPGGLKVRRRARELHRKLEEEWRQNRPNPLAANDWLSVYAMAVNEENAAGGRVVTAPTNGAAGVVPAVMRYWLRFHPEAD
RNGIRDFLLTAAAIGGLIKFNASISGAEVGCQGEVGSASAMAAAGLAAVMGGTPEQVENAAEIALEHHLGMTCDPVAGLV
QVPCIERNALGAVKAVTAASLAIKGDGQHFVSLDAAVETMRQTGLDMNERYKETSLGGLAVNVVEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1789161, Length=466, Percent_Identity=48.9270386266094, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI48994925, Length=465, Percent_Identity=50.1075268817204, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI1788116, Length=463, Percent_Identity=47.732181425486, Blast_Score=419, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49796; Mature: 49796

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLSVFDLFKIGIGPSSSHTMGPMVAAERFLREIAEGEWPRPAGVQVNRLSVSLHGSLAF
CEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCEEE
TGVGHATDRAAILGLQGFTPTTVDPDQADSILEQIGSTKRLSPAGHPEYRFDPETDLVFD
EECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEE
RKAPLPGHANGMAFSAFDADDRLLLRRVYYSVGGGFVVSQEELEALKAEKRPGADSSVPY
CCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHCCCCCCCCCCC
PFTNARQMLEMAASSGLSIAEMKRANELAHRSAQELDAGLDRIWDAMHGCIERGLTQEGI
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
MPGGLKVRRRARELHRKLEEEWRQNRPNPLAANDWLSVYAMAVNEENAAGGRVVTAPTNG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEEECCCCCCCCEEEECCCCC
AAGVVPAVMRYWLRFHPEADRNGIRDFLLTAAAIGGLIKFNASISGAEVGCQGEVGSASA
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCHHH
MAAAGLAAVMGGTPEQVENAAEIALEHHLGMTCDPVAGLVQVPCIERNALGAVKAVTAAS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHH
LAIKGDGQHFVSLDAAVETMRQTGLDMNERYKETSLGGLAVNVVEC
EEEECCCCEEEEHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure
MFLSVFDLFKIGIGPSSSHTMGPMVAAERFLREIAEGEWPRPAGVQVNRLSVSLHGSLAF
CEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCEEE
TGVGHATDRAAILGLQGFTPTTVDPDQADSILEQIGSTKRLSPAGHPEYRFDPETDLVFD
EECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEE
RKAPLPGHANGMAFSAFDADDRLLLRRVYYSVGGGFVVSQEELEALKAEKRPGADSSVPY
CCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHCCCCCCCCCCC
PFTNARQMLEMAASSGLSIAEMKRANELAHRSAQELDAGLDRIWDAMHGCIERGLTQEGI
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
MPGGLKVRRRARELHRKLEEEWRQNRPNPLAANDWLSVYAMAVNEENAAGGRVVTAPTNG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEEEECCCCCCCCEEEECCCCC
AAGVVPAVMRYWLRFHPEADRNGIRDFLLTAAAIGGLIKFNASISGAEVGCQGEVGSASA
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCHHH
MAAAGLAAVMGGTPEQVENAAEIALEHHLGMTCDPVAGLVQVPCIERNALGAVKAVTAAS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHH
LAIKGDGQHFVSLDAAVETMRQTGLDMNERYKETSLGGLAVNVVEC
EEEECCCCEEEEHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]