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The map label for this gene is dppA [H]

Identifier: 110633666

GI number: 110633666

Start: 1404142

End: 1405623

Strand: Reverse

Name: dppA [H]

Synonym: Meso_1313

Alternate gene names: 110633666

Gene position: 1405623-1404142 (Counterclockwise)

Preceding gene: 110633668

Following gene: 110633665

Centisome position: 31.86

GC content: 59.72

Gene sequence:

>1482_bases
ATGAGAATGTTTGCACGATCGCTGGCCGCGGCTGTCATTCTGGCCGCTTCGGCTTCCGCAGCTCTGAGCGCGCGGACAGA
CCTCGTGCTGGGCGTCGTGCTCGAGCCGCCGCATCTCGACCCCACGGCGGGGGCTGCCGCGGCAATCGACGAGATTGTCT
ACGCCAATATCTTCGAGGGCCTTACCCGTATTGGCCCCAACGGCGATGTCGTACCGGCTCTCGCCGAGAGCTGGGAGATC
TCAGAGGACGGCAAGATCTACACGTTCAAGCTGCGTGAGGGCGTCAAATATCACGACGGGACAAGCTTCGATGCCGAGGA
TGTGAAATTCTCGATCGAGCGCGCGATGGGGAAAGATTCGACCAATGCGCAGAAAGTGCTCTTCTCGGGGATCCAAACCG
TCGAGGTGGTGGATCCCACGACCGTGAAGGTCACGCTCCAGCAGCCGCAGGGCTCGTTTCTTTACAATATGGCCTGGGGC
GATGCCGTTATCGTCGCGCCCGAATCGGCCGACGGCAATAAGGAGAAGCCCATCGGCACCGGCCCGTTCAAATTCGGAAA
CTGGGCAAAAGGCTCGTCTGTCACGATTACAAGGAATCCGGAGTATTGGGGCGAGCCAGCGCGTCTGGAAAAGGCCGAGT
TCCGCTTCATCCCGGATGCAGCGGCCGCCGTGGCGGCGCTGCTTTCAGGCGATGTGCAGGCGTTCCCCAATCTGCAGGCC
GGGGACGCGCTGCCGCAGATCGAGGCCGATCCGCGCTTCAAGGTTGTCATCGGCGCCACCGAGGGCGAGACGATCCTGGC
GATGAACAATGGCAAGGAGCCCTTCAATAATCTGAAGGTGCGTCAGGCGATCTCTCATGCCGTCAATCGCGACGAGGTGA
TCCTCGGCGCCACCAACAGCCATGGCGTACCGATCGGTTCTCACTTCTCACCGGCAAATTCCGCCTATGTGGACCTTACC
GGCACCTACCCGTATGATCCCGAGAAAGCCAAGGCGCTTCTGGCCGAGGCCGGCTATCCTGACGGCTTTTCGGCGACGCT
GAAGCTTCCGCCGCCGCCCTATGCACGGCTTGGCGGTGAAATCATCGCCTCCGAATTGCGGGAGGTGGGGATCAATCTCG
AGATCATTCCCATGGAATGGGCCCAGTGGCTGGAGCAGGTCTTCACCAATAAAGAATTTGACCTCACCATCATCTCCCAC
ACGGAGCCGAACGACATCAACATCTATGCGCGCGACGATTATTACTTCAGTTACCGGAACCCCAGGTTCAACGAGATCAT
GACGAAGCTCGACGCCACCGTCGAACCCGAAAAGCGAAAGGAACTTTACGGGCAGGCGCAGCGCATCATCGCTGAGGATG
CGGTGAACGTGTTCCTCTTCCAGCTCCCGAAGATCGGGGTGTGGGACGCGAAGCTCGAAGGCATGTGGGAGAATATGCCC
ATCCAGGCAAACGATCTCACCAAGGTGCGTTGGGTGGATTGA

Upstream 100 bases:

>100_bases
GGCCGACGATAACAAGTGCGATCTATTCGCCCTTGGATTCAGGCTTCAATCATTGCAGAACATGCACCTTCAATCAGATG
CCGGATTTGGGGAGTGACGA

Downstream 100 bases:

>100_bases
GATCTCGGGGAACCTTGAAGGCTTGCGCTCTACGTGGCCCCCCTCTGGCCTGCCGGCCATCTCCCCCACGAGGGGGGAGA
TTGGCTGTGGCAACCTTTGC

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MRMFARSLAAAVILAASASAALSARTDLVLGVVLEPPHLDPTAGAAAAIDEIVYANIFEGLTRIGPNGDVVPALAESWEI
SEDGKIYTFKLREGVKYHDGTSFDAEDVKFSIERAMGKDSTNAQKVLFSGIQTVEVVDPTTVKVTLQQPQGSFLYNMAWG
DAVIVAPESADGNKEKPIGTGPFKFGNWAKGSSVTITRNPEYWGEPARLEKAEFRFIPDAAAAVAALLSGDVQAFPNLQA
GDALPQIEADPRFKVVIGATEGETILAMNNGKEPFNNLKVRQAISHAVNRDEVILGATNSHGVPIGSHFSPANSAYVDLT
GTYPYDPEKAKALLAEAGYPDGFSATLKLPPPPYARLGGEIIASELREVGINLEIIPMEWAQWLEQVFTNKEFDLTIISH
TEPNDINIYARDDYYFSYRNPRFNEIMTKLDATVEPEKRKELYGQAQRIIAEDAVNVFLFQLPKIGVWDAKLEGMWENMP
IQANDLTKVRWVD

Sequences:

>Translated_493_residues
MRMFARSLAAAVILAASASAALSARTDLVLGVVLEPPHLDPTAGAAAAIDEIVYANIFEGLTRIGPNGDVVPALAESWEI
SEDGKIYTFKLREGVKYHDGTSFDAEDVKFSIERAMGKDSTNAQKVLFSGIQTVEVVDPTTVKVTLQQPQGSFLYNMAWG
DAVIVAPESADGNKEKPIGTGPFKFGNWAKGSSVTITRNPEYWGEPARLEKAEFRFIPDAAAAVAALLSGDVQAFPNLQA
GDALPQIEADPRFKVVIGATEGETILAMNNGKEPFNNLKVRQAISHAVNRDEVILGATNSHGVPIGSHFSPANSAYVDLT
GTYPYDPEKAKALLAEAGYPDGFSATLKLPPPPYARLGGEIIASELREVGINLEIIPMEWAQWLEQVFTNKEFDLTIISH
TEPNDINIYARDDYYFSYRNPRFNEIMTKLDATVEPEKRKELYGQAQRIIAEDAVNVFLFQLPKIGVWDAKLEGMWENMP
IQANDLTKVRWVD
>Mature_493_residues
MRMFARSLAAAVILAASASAALSARTDLVLGVVLEPPHLDPTAGAAAAIDEIVYANIFEGLTRIGPNGDVVPALAESWEI
SEDGKIYTFKLREGVKYHDGTSFDAEDVKFSIERAMGKDSTNAQKVLFSGIQTVEVVDPTTVKVTLQQPQGSFLYNMAWG
DAVIVAPESADGNKEKPIGTGPFKFGNWAKGSSVTITRNPEYWGEPARLEKAEFRFIPDAAAAVAALLSGDVQAFPNLQA
GDALPQIEADPRFKVVIGATEGETILAMNNGKEPFNNLKVRQAISHAVNRDEVILGATNSHGVPIGSHFSPANSAYVDLT
GTYPYDPEKAKALLAEAGYPDGFSATLKLPPPPYARLGGEIIASELREVGINLEIIPMEWAQWLEQVFTNKEFDLTIISH
TEPNDINIYARDDYYFSYRNPRFNEIMTKLDATVEPEKRKELYGQAQRIIAEDAVNVFLFQLPKIGVWDAKLEGMWENMP
IQANDLTKVRWVD

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=490, Percent_Identity=31.4285714285714, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1787052, Length=493, Percent_Identity=28.8032454361055, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1789887, Length=345, Percent_Identity=30.7246376811594, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1787762, Length=488, Percent_Identity=26.844262295082, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1787551, Length=462, Percent_Identity=24.2424242424242, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787495, Length=511, Percent_Identity=24.26614481409, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1789397, Length=512, Percent_Identity=24.0234375, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI87081878, Length=516, Percent_Identity=24.2248062015504, Blast_Score=101, Evalue=9e-23,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 53994; Mature: 53994

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMFARSLAAAVILAASASAALSARTDLVLGVVLEPPHLDPTAGAAAAIDEIVYANIFEG
CCHHHHHHHHHHHHHHCCHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
LTRIGPNGDVVPALAESWEISEDGKIYTFKLREGVKYHDGTSFDAEDVKFSIERAMGKDS
HHHCCCCCCCCHHHHCCCCCCCCCCEEEEEECCCCEECCCCCCCHHHHHHHHHHHCCCCC
TNAQKVLFSGIQTVEVVDPTTVKVTLQQPQGSFLYNMAWGDAVIVAPESADGNKEKPIGT
CCHHHHHHCCCCEEEEECCCEEEEEEECCCCCEEEEEECCCEEEEECCCCCCCCCCCCCC
GPFKFGNWAKGSSVTITRNPEYWGEPARLEKAEFRFIPDAAAAVAALLSGDVQAFPNLQA
CCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCHHHHHHHHHHCCCHHHCCCCCC
GDALPQIEADPRFKVVIGATEGETILAMNNGKEPFNNLKVRQAISHAVNRDEVILGATNS
CCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCC
HGVPIGSHFSPANSAYVDLTGTYPYDPEKAKALLAEAGYPDGFSATLKLPPPPYARLGGE
CCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHCHH
IIASELREVGINLEIIPMEWAQWLEQVFTNKEFDLTIISHTEPNDINIYARDDYYFSYRN
HHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEECCEEEEECC
PRFNEIMTKLDATVEPEKRKELYGQAQRIIAEDAVNVFLFQLPKIGVWDAKLEGMWENMP
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEECHHHCCHHCCCC
IQANDLTKVRWVD
CCCCCCCEEEECC
>Mature Secondary Structure
MRMFARSLAAAVILAASASAALSARTDLVLGVVLEPPHLDPTAGAAAAIDEIVYANIFEG
CCHHHHHHHHHHHHHHCCHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
LTRIGPNGDVVPALAESWEISEDGKIYTFKLREGVKYHDGTSFDAEDVKFSIERAMGKDS
HHHCCCCCCCCHHHHCCCCCCCCCCEEEEEECCCCEECCCCCCCHHHHHHHHHHHCCCCC
TNAQKVLFSGIQTVEVVDPTTVKVTLQQPQGSFLYNMAWGDAVIVAPESADGNKEKPIGT
CCHHHHHHCCCCEEEEECCCEEEEEEECCCCCEEEEEECCCEEEEECCCCCCCCCCCCCC
GPFKFGNWAKGSSVTITRNPEYWGEPARLEKAEFRFIPDAAAAVAALLSGDVQAFPNLQA
CCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCHHHHHHHHHHCCCHHHCCCCCC
GDALPQIEADPRFKVVIGATEGETILAMNNGKEPFNNLKVRQAISHAVNRDEVILGATNS
CCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCC
HGVPIGSHFSPANSAYVDLTGTYPYDPEKAKALLAEAGYPDGFSATLKLPPPPYARLGGE
CCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHCHH
IIASELREVGINLEIIPMEWAQWLEQVFTNKEFDLTIISHTEPNDINIYARDDYYFSYRN
HHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEECCEEEEECC
PRFNEIMTKLDATVEPEKRKELYGQAQRIIAEDAVNVFLFQLPKIGVWDAKLEGMWENMP
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEECHHHCCHHCCCC
IQANDLTKVRWVD
CCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]