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The map label for this gene is ykoU [H]

Identifier: 110633503

GI number: 110633503

Start: 1256494

End: 1259031

Strand: Direct

Name: ykoU [H]

Synonym: Meso_1150

Alternate gene names: 110633503

Gene position: 1256494-1259031 (Clockwise)

Preceding gene: 110633502

Following gene: 110633505

Centisome position: 28.48

GC content: 62.73

Gene sequence:

>2538_bases
ATGGCGCTCACCACCTATCGCAGGAAGCGGAACTTTTCAGCTACGCCCGAGCCTCCGGGTGAGGAGAAGGCTTCGCCGCG
CGGCGATAGTTTCGTGATCCAAAAGCACGCCGCGCGCCGCCTTCATTACGATCTTCGGCTGGAGATGGATGGGGTTCTCA
AGAGTTGGGCGGTCACGCGCGGGCCGAGTCTCGTGCCGGGCGAAAAGCGGCTTGCCGTCCATGTGGAGGATCACCCGCTC
GATTATGGCGATTTCGAAGGGACCATTCCCAAGGGCGAATATGGCGGCGGGACCGTTATCGTCTGGGACCGCGGAAGCTG
GTCTCCGATCGGTGATGCGAAAAAGGGTTATGCCAAGGGCCATCTGGAATTCGAATTGCACGGCGAGAAGCTGACGGGCC
GCTGGCATCTGGTGCGCATGGCGAAGAAGCCGCGCGAGAAGAAGGAAAACTGGCTGCTCATTAAGGGCGAGGACGATGCC
GCGCGCAGCGAGGCTGATCCGGATATTCTGGAGGAGCGCCCGGAGTCGGTGAAAACCGGACGGGTGATCGAAGAGGTGGA
AGGCGAGGCGCCGGGCTGGTCGTCGAAGACCGGGCGGATCGAGCAGCCGGCGGAGGCAAAACCGGCGCGGAAGAAGCGCG
CGACCAAGGCCGGTAGCGAGAAATCCGCTGGCGAGAAAATTTCGGTACCCAAGCGGGCGAAGAAAGCGGGCTATCCCGGC
TTCATAGAGCCGGCGCTCGCCACATTGCGCAGCACGCCTCCGCCCGGCGGCAGGTGGTTGCACGAGATCAAGTTCGACGG
CTATCGGCTGCAAGCGCATATCCGCGACGGCAAAGCGCGGCTATTGACGCGCAGCGGCCTCGACTGGACCGAAAAATTTG
GGGACGCGATCGTGACCGCCTTGGGCAGCCTTCCCGTCCGGCAGGCCATTATGGACGGAGAACTGATCGTGGAGGGAGCG
GGCGGCGCTTCGGACTTCTCCGCCCTCCAGGCAGCGCTATCCGAAGGTCGCGTCGACCGCATGGCGCTCTATCTGTTCGA
CCTGCTCTATCTTGACGGCTACGACTTCCGCCCCGTTCCGCTGGCTGAGAGAAAAGCCACCCTCCAGAAGCTCCTCGATG
GCGCGCCACCAGTCCTGCGCTACAGCGAGCATTTCGAAGAGGATGGCGAGCTTGTTTTCCGCCATGCCTGCCGCCTGAGT
CTTGAAGGCATTGTCTCGAAGGCCGGCGATGCGGCCTATCGTTCCGGGCGCGGCAAGGATTGGATCAAGTCGAAATGTTC
CATGCGGCAGGAGTTCGTCGTCGCGGGTTACGTGCCATCCACCACCTCCAACCGCGCCATCGGTTCACTGGTGCTGGGCT
ATTATGAAAACGAGCGGTTGATATATGCCGGCCGTGTCGGCACCGGCTTCAGCCATGCGCTTGCGCAGGATCTTTTCAAG
CGTCTGGATAAAATGCGCATCGCGAAAAGCCCCTTCGCAAAGAAGCTGACGTCTGAAGAAGCGCGCGGCGCGAAATTCGT
GCGGCCCGAGCTCGTGGCGGAAGTGGAGTTTCGGACTTGGACAGCCGACAACTTGATCCGCCATGCCTCCTTCCGGGGTC
TGCGGGAGGATAAAAGCGCGACGGATGTCACCCGCGAGACGAACCAATCCAAGCCCGCCGAGCGCGCGGCGCCTGCAATC
AGGCTTACGCACCCGGACCGGATTTACTGGAAGGATGCCGGTGTCACCAAGCAGGGGCTCTCGGACTATTATGCGGAAGT
CTGGCCGCGCATGGGTCCTTTCATCGTCAATCGTCCGCTGGCGCTTGTGCGCTGTCCCGATGGTGTTGAGGGCCAGTGCT
TCTTTCAGAAGCATGCCTGGCGCGGTCAATCCCACGAGATCATGAAAGCCGTAGACCCGGAGGACGACGAGCCCATTATC
GCCATCGATGGTCTGCCGGGCCTGATAGGGCTTGTGCAGGGCGGCACGCTGGAGATCCACCCGTGGGGATCGCAACTGGA
GGATCTGGAGCGCCCCGACCTCATTAATATGGACCTTGATCCTGGCCCGGATGTCACCTGGCAGGACGTGATCGATGCCG
CAAGGGAGGTGCGCGAGCGGCTGGCGCAAGCGGGCCTTGAAAGCTTTGTGAAGACGTCCGGCGGCAAGGGCCTGCATGTT
GTGGCGCCGCTGAAGCCGCGCGCGGATTGGCCTGAGGTGAAGGCCTTCGCAAAGGGCATCGCCGATGCGATGGCTTCCGA
CACACCCGAGCGCTTCGTTGCCACCGTGACGAAAGCCAAGCGCAAGGGAAAGATCCTTGTCGACTATCTTCGCAACGGCA
GGGGGGCGACGGCCGTCGCACCCTATTCCACACGGGCGCGGGCGGGGGCGGCGGTGTCGATGCCGCTGTTCTGGGAGGAA
CTGAGCCCCGCCATCACCGCCGATTATTTTACCGTGGCCAATGCTCCAACACGTTTGGCCGCCATTGGGAAGGACCCGTG
GGAGGATTTTTGGCGGGCGGCGGTGCCGCTTGGCAGGAAGGCGCGCCGCGCCGCGTGA

Upstream 100 bases:

>100_bases
AGGCTCTGCGCCAAAGCGCGGGAGCAGGCAAGGCACCGAAGAAGACGCGCGCCGGCACGCGCAAGAAGAGTGCTTCCGGC
GAGCGCCGCAAGGCGGGCTG

Downstream 100 bases:

>100_bases
GTTTCACCTGCTCCGCTTCTTCTCCTCGGTGATGGAGCGCTTAAGCGCATCCATGATGCTGATGACGTTATCCGGTGGCT
CCGGCTCATCTTCCTTCGTC

Product: ATP dependent DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 845; Mature: 844

Protein sequence:

>845_residues
MALTTYRRKRNFSATPEPPGEEKASPRGDSFVIQKHAARRLHYDLRLEMDGVLKSWAVTRGPSLVPGEKRLAVHVEDHPL
DYGDFEGTIPKGEYGGGTVIVWDRGSWSPIGDAKKGYAKGHLEFELHGEKLTGRWHLVRMAKKPREKKENWLLIKGEDDA
ARSEADPDILEERPESVKTGRVIEEVEGEAPGWSSKTGRIEQPAEAKPARKKRATKAGSEKSAGEKISVPKRAKKAGYPG
FIEPALATLRSTPPPGGRWLHEIKFDGYRLQAHIRDGKARLLTRSGLDWTEKFGDAIVTALGSLPVRQAIMDGELIVEGA
GGASDFSALQAALSEGRVDRMALYLFDLLYLDGYDFRPVPLAERKATLQKLLDGAPPVLRYSEHFEEDGELVFRHACRLS
LEGIVSKAGDAAYRSGRGKDWIKSKCSMRQEFVVAGYVPSTTSNRAIGSLVLGYYENERLIYAGRVGTGFSHALAQDLFK
RLDKMRIAKSPFAKKLTSEEARGAKFVRPELVAEVEFRTWTADNLIRHASFRGLREDKSATDVTRETNQSKPAERAAPAI
RLTHPDRIYWKDAGVTKQGLSDYYAEVWPRMGPFIVNRPLALVRCPDGVEGQCFFQKHAWRGQSHEIMKAVDPEDDEPII
AIDGLPGLIGLVQGGTLEIHPWGSQLEDLERPDLINMDLDPGPDVTWQDVIDAAREVRERLAQAGLESFVKTSGGKGLHV
VAPLKPRADWPEVKAFAKGIADAMASDTPERFVATVTKAKRKGKILVDYLRNGRGATAVAPYSTRARAGAAVSMPLFWEE
LSPAITADYFTVANAPTRLAAIGKDPWEDFWRAAVPLGRKARRAA

Sequences:

>Translated_845_residues
MALTTYRRKRNFSATPEPPGEEKASPRGDSFVIQKHAARRLHYDLRLEMDGVLKSWAVTRGPSLVPGEKRLAVHVEDHPL
DYGDFEGTIPKGEYGGGTVIVWDRGSWSPIGDAKKGYAKGHLEFELHGEKLTGRWHLVRMAKKPREKKENWLLIKGEDDA
ARSEADPDILEERPESVKTGRVIEEVEGEAPGWSSKTGRIEQPAEAKPARKKRATKAGSEKSAGEKISVPKRAKKAGYPG
FIEPALATLRSTPPPGGRWLHEIKFDGYRLQAHIRDGKARLLTRSGLDWTEKFGDAIVTALGSLPVRQAIMDGELIVEGA
GGASDFSALQAALSEGRVDRMALYLFDLLYLDGYDFRPVPLAERKATLQKLLDGAPPVLRYSEHFEEDGELVFRHACRLS
LEGIVSKAGDAAYRSGRGKDWIKSKCSMRQEFVVAGYVPSTTSNRAIGSLVLGYYENERLIYAGRVGTGFSHALAQDLFK
RLDKMRIAKSPFAKKLTSEEARGAKFVRPELVAEVEFRTWTADNLIRHASFRGLREDKSATDVTRETNQSKPAERAAPAI
RLTHPDRIYWKDAGVTKQGLSDYYAEVWPRMGPFIVNRPLALVRCPDGVEGQCFFQKHAWRGQSHEIMKAVDPEDDEPII
AIDGLPGLIGLVQGGTLEIHPWGSQLEDLERPDLINMDLDPGPDVTWQDVIDAAREVRERLAQAGLESFVKTSGGKGLHV
VAPLKPRADWPEVKAFAKGIADAMASDTPERFVATVTKAKRKGKILVDYLRNGRGATAVAPYSTRARAGAAVSMPLFWEE
LSPAITADYFTVANAPTRLAAIGKDPWEDFWRAAVPLGRKARRAA
>Mature_844_residues
ALTTYRRKRNFSATPEPPGEEKASPRGDSFVIQKHAARRLHYDLRLEMDGVLKSWAVTRGPSLVPGEKRLAVHVEDHPLD
YGDFEGTIPKGEYGGGTVIVWDRGSWSPIGDAKKGYAKGHLEFELHGEKLTGRWHLVRMAKKPREKKENWLLIKGEDDAA
RSEADPDILEERPESVKTGRVIEEVEGEAPGWSSKTGRIEQPAEAKPARKKRATKAGSEKSAGEKISVPKRAKKAGYPGF
IEPALATLRSTPPPGGRWLHEIKFDGYRLQAHIRDGKARLLTRSGLDWTEKFGDAIVTALGSLPVRQAIMDGELIVEGAG
GASDFSALQAALSEGRVDRMALYLFDLLYLDGYDFRPVPLAERKATLQKLLDGAPPVLRYSEHFEEDGELVFRHACRLSL
EGIVSKAGDAAYRSGRGKDWIKSKCSMRQEFVVAGYVPSTTSNRAIGSLVLGYYENERLIYAGRVGTGFSHALAQDLFKR
LDKMRIAKSPFAKKLTSEEARGAKFVRPELVAEVEFRTWTADNLIRHASFRGLREDKSATDVTRETNQSKPAERAAPAIR
LTHPDRIYWKDAGVTKQGLSDYYAEVWPRMGPFIVNRPLALVRCPDGVEGQCFFQKHAWRGQSHEIMKAVDPEDDEPIIA
IDGLPGLIGLVQGGTLEIHPWGSQLEDLERPDLINMDLDPGPDVTWQDVIDAAREVRERLAQAGLESFVKTSGGKGLHVV
APLKPRADWPEVKAFAKGIADAMASDTPERFVATVTKAKRKGKILVDYLRNGRGATAVAPYSTRARAGAAVSMPLFWEEL
SPAITADYFTVANAPTRLAAIGKDPWEDFWRAAVPLGRKARRAA

Specific function: Probably involved in the repair of DNA double-strand breaks by non-homologous-end joining (NHEJ) during spore germination [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR014145
- InterPro:   IPR014143 [H]

Pfam domain/function: PF01068 DNA_ligase_A_M [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 93528; Mature: 93397

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTTYRRKRNFSATPEPPGEEKASPRGDSFVIQKHAARRLHYDLRLEMDGVLKSWAVTR
CCCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCEEEEEEHHHHHHHHHHCC
GPSLVPGEKRLAVHVEDHPLDYGDFEGTIPKGEYGGGTVIVWDRGSWSPIGDAKKGYAKG
CCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCC
HLEFELHGEKLTGRWHLVRMAKKPREKKENWLLIKGEDDAARSEADPDILEERPESVKTG
EEEEEECCCEECCHHEEHHHHHCCCCCCCCEEEEECCCCHHCCCCCHHHHHCCCCHHHHH
RVIEEVEGEAPGWSSKTGRIEQPAEAKPARKKRATKAGSEKSAGEKISVPKRAKKAGYPG
HHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCC
FIEPALATLRSTPPPGGRWLHEIKFDGYRLQAHIRDGKARLLTRSGLDWTEKFGDAIVTA
CHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHH
LGSLPVRQAIMDGELIVEGAGGASDFSALQAALSEGRVDRMALYLFDLLYLDGYDFRPVP
HHCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC
LAERKATLQKLLDGAPPVLRYSEHFEEDGELVFRHACRLSLEGIVSKAGDAAYRSGRGKD
HHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHH
WIKSKCSMRQEFVVAGYVPSTTSNRAIGSLVLGYYENERLIYAGRVGTGFSHALAQDLFK
HHHHHHHHHHCEEEEECCCCCCCCHHHHHHHEEEEECCEEEEEECCCCCHHHHHHHHHHH
RLDKMRIAKSPFAKKLTSEEARGAKFVRPELVAEVEFRTWTADNLIRHASFRGLREDKSA
HHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHEEEEEEEECHHHHHHHHHHCCCCCCCCH
TDVTRETNQSKPAERAAPAIRLTHPDRIYWKDAGVTKQGLSDYYAEVWPRMGPFIVNRPL
HHHHHHCCCCCCHHHCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEECCCE
ALVRCPDGVEGQCFFQKHAWRGQSHEIMKAVDPEDDEPIIAIDGLPGLIGLVQGGTLEIH
EEEECCCCCCCCEEEEHHCCCCCCHHHHHHCCCCCCCCEEEECCCCHHHHHCCCCEEEEE
PWGSQLEDLERPDLINMDLDPGPDVTWQDVIDAAREVRERLAQAGLESFVKTSGGKGLHV
CCCCHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VAPLKPRADWPEVKAFAKGIADAMASDTPERFVATVTKAKRKGKILVDYLRNGRGATAVA
EECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEHHHCCCCCEEEC
PYSTRARAGAAVSMPLFWEELSPAITADYFTVANAPTRLAAIGKDPWEDFWRAAVPLGRK
CCCCHHCCCCEEECCHHHHHCCCCCEECEEEECCCCCCEEECCCCHHHHHHHHHCCCCCH
ARRAA
HHCCC
>Mature Secondary Structure 
ALTTYRRKRNFSATPEPPGEEKASPRGDSFVIQKHAARRLHYDLRLEMDGVLKSWAVTR
CCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCEEEEEEHHHHHHHHHHCC
GPSLVPGEKRLAVHVEDHPLDYGDFEGTIPKGEYGGGTVIVWDRGSWSPIGDAKKGYAKG
CCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCC
HLEFELHGEKLTGRWHLVRMAKKPREKKENWLLIKGEDDAARSEADPDILEERPESVKTG
EEEEEECCCEECCHHEEHHHHHCCCCCCCCEEEEECCCCHHCCCCCHHHHHCCCCHHHHH
RVIEEVEGEAPGWSSKTGRIEQPAEAKPARKKRATKAGSEKSAGEKISVPKRAKKAGYPG
HHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCC
FIEPALATLRSTPPPGGRWLHEIKFDGYRLQAHIRDGKARLLTRSGLDWTEKFGDAIVTA
CHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHH
LGSLPVRQAIMDGELIVEGAGGASDFSALQAALSEGRVDRMALYLFDLLYLDGYDFRPVP
HHCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCC
LAERKATLQKLLDGAPPVLRYSEHFEEDGELVFRHACRLSLEGIVSKAGDAAYRSGRGKD
HHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHH
WIKSKCSMRQEFVVAGYVPSTTSNRAIGSLVLGYYENERLIYAGRVGTGFSHALAQDLFK
HHHHHHHHHHCEEEEECCCCCCCCHHHHHHHEEEEECCEEEEEECCCCCHHHHHHHHHHH
RLDKMRIAKSPFAKKLTSEEARGAKFVRPELVAEVEFRTWTADNLIRHASFRGLREDKSA
HHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHEEEEEEEECHHHHHHHHHHCCCCCCCCH
TDVTRETNQSKPAERAAPAIRLTHPDRIYWKDAGVTKQGLSDYYAEVWPRMGPFIVNRPL
HHHHHHCCCCCCHHHCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEECCCE
ALVRCPDGVEGQCFFQKHAWRGQSHEIMKAVDPEDDEPIIAIDGLPGLIGLVQGGTLEIH
EEEECCCCCCCCEEEEHHCCCCCCHHHHHHCCCCCCCCEEEECCCCHHHHHCCCCEEEEE
PWGSQLEDLERPDLINMDLDPGPDVTWQDVIDAAREVRERLAQAGLESFVKTSGGKGLHV
CCCCHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VAPLKPRADWPEVKAFAKGIADAMASDTPERFVATVTKAKRKGKILVDYLRNGRGATAVA
EECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEHHHCCCCCEEEC
PYSTRARAGAAVSMPLFWEELSPAITADYFTVANAPTRLAAIGKDPWEDFWRAAVPLGRK
CCCCHHCCCCEEECCHHHHHCCCCCEECEEEECCCCCCEEECCCCHHHHHHHHHCCCCCH
ARRAA
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]