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The map label for this gene is nrdR

Identifier: 110633488

GI number: 110633488

Start: 1243157

End: 1243621

Strand: Direct

Name: nrdR

Synonym: Meso_1135

Alternate gene names: 110633488

Gene position: 1243157-1243621 (Clockwise)

Preceding gene: 110633487

Following gene: 110633489

Centisome position: 28.17

GC content: 63.01

Gene sequence:

>465_bases
ATGCGCTGTCCCTATTGCCAGTCGGAAGACACCCAGGTGAAGGATTCGCGGCCCGCCGAAGATGGCGCCGCGATCCGCCG
CCGCCGTGCCTGTCCCGTCTGCGGCGGCCGCTTCACCACCTTCGAGCGCGTGCAGCTGCGCGATCTGGTCGTGGTGAAGA
GGACCGGCCGCAAGGTGCCTTTCGACCGCGATAAGCTGCATCGATCCTTCGAGATCGCGCTTAGGAAGCGTAATGTCGAT
CCTGATCGGGTTGAGCGTGCCGTAACCGGCATCGTGCGGCAGCTCGAAAGCTTCGGGGAGAACGAGATTAGTACGGACGA
TATCGGCCTGCTCGTCATGGAGGCGCTGAAGTCGCTCGACGACGTTGCCTATGTCCGCTACGCCTCGGTCTATCGGAATT
TCCGCGAGGCGAAGGATTTCCAGGACGTGCTCGGCGAGCTGAGAGGCGAGCCGGAGCTGGAGTAG

Upstream 100 bases:

>100_bases
GCGGTGAAGAAAAAGGTGATTGCCCTTACCGAACGTTTCCCGCTCTATTCATATCTGGACTGAGCGCTGAGAAGCGCGGG
TTTGACGAGCGGAAGCTGAG

Downstream 100 bases:

>100_bases
ACGGGGTGAACACCCTAGATAGCCACATTGAGACGGTTTAGATGCCTAGCGCCCCAATTTCCGCGCACGACCGCCGCTTC
ATGGCGGCGGCGGTCCGGCT

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MRCPYCQSEDTQVKDSRPAEDGAAIRRRRACPVCGGRFTTFERVQLRDLVVVKRTGRKVPFDRDKLHRSFEIALRKRNVD
PDRVERAVTGIVRQLESFGENEISTDDIGLLVMEALKSLDDVAYVRYASVYRNFREAKDFQDVLGELRGEPELE

Sequences:

>Translated_154_residues
MRCPYCQSEDTQVKDSRPAEDGAAIRRRRACPVCGGRFTTFERVQLRDLVVVKRTGRKVPFDRDKLHRSFEIALRKRNVD
PDRVERAVTGIVRQLESFGENEISTDDIGLLVMEALKSLDDVAYVRYASVYRNFREAKDFQDVLGELRGEPELE
>Mature_154_residues
MRCPYCQSEDTQVKDSRPAEDGAAIRRRRACPVCGGRFTTFERVQLRDLVVVKRTGRKVPFDRDKLHRSFEIALRKRNVD
PDRVERAVTGIVRQLESFGENEISTDDIGLLVMEALKSLDDVAYVRYASVYRNFREAKDFQDVLGELRGEPELE

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=47.6190476190476, Blast_Score=129, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_MESSB (Q11J94)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_673696.1
- STRING:   Q11J94
- GeneID:   4182543
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_1135
- NMPDR:   fig|266779.1.peg.2451
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   Q11J94
- ProtClustDB:   PRK00464
- BioCyc:   MSP266779:MESO_1135-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17781; Mature: 17781

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPYCQSEDTQVKDSRPAEDGAAIRRRRACPVCGGRFTTFERVQLRDLVVVKRTGRKVP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
FDRDKLHRSFEIALRKRNVDPDRVERAVTGIVRQLESFGENEISTDDIGLLVMEALKSLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
DVAYVRYASVYRNFREAKDFQDVLGELRGEPELE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRCPYCQSEDTQVKDSRPAEDGAAIRRRRACPVCGGRFTTFERVQLRDLVVVKRTGRKVP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
FDRDKLHRSFEIALRKRNVDPDRVERAVTGIVRQLESFGENEISTDDIGLLVMEALKSLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
DVAYVRYASVYRNFREAKDFQDVLGELRGEPELE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA