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The map label for this gene is degA [H]

Identifier: 110633447

GI number: 110633447

Start: 1198842

End: 1199897

Strand: Direct

Name: degA [H]

Synonym: Meso_1093

Alternate gene names: 110633447

Gene position: 1198842-1199897 (Clockwise)

Preceding gene: 110633446

Following gene: 110633448

Centisome position: 27.17

GC content: 65.72

Gene sequence:

>1056_bases
ATGTCTCAAAGAGCCACGCAAAAACAAGTCGCCGAGAGGGCAGGCGTCGCGCAGGCGACGGTCTCGCTTGTCCTCAATGG
CGGCCGCGACAAGGTGGCGCCCGAAACAGCAGAGCGCATCGAGGCGGCGATTTCCGAGCTCGGCTATCAGCCGAACCGCT
TCGCACAGGCGCTTCGCACCAAGCGGACCCATGTCATCGCCTGTGTCGTGCCCGACCTTACAAACCCTTTTTACCCCTCG
CTCGTGGTCGCAGTGCAGAAGATCGCCCGCGCTGCAGGCTACGAGGTGGTGACCATCGACACCGAGGGAGAGCTTGCCAA
CGAACTGCAGGTGATCCTCGCCGCCCAGCAGGGCCGGTTCGACGGAGTCGTCGGCGTGTTCTTCAAGGCCAACGCCCGGG
ATCTCGCTCCGCTCGGCAAAAGCGGCGTGCCCGTGGTCCGTATCGAGGTCAGCCGCAAGGCCGGCGGCCCGCTGCCGATT
GACGATCTGTTCATCGACAATGTCGCCGCCGCCCGCGCATTGACGCTCCACCTTCTCGAGCTCGGCCATCGGTCGATTGC
CATGATCGCCGCCCCCGGCGGACCGCAGCAGGTGCGCCTGCAAGGTTATCTCGAGGCGATGGCGACGATCGGGGCCGAGC
CGATTGTGCTCGAAGCCGCTCATTTCACGCTGGAGGCTGGACGCGAAGTCGCCGACCGGCTGATCGAAAGCGGCCGCTCC
GTCAGCGCCATTATCGCCGCCAACGACCTGATGGCCATCGGCGTCATGCAGGGGCTGGCGGCCAATGGGCTCTCGGTGCC
TGGCGACGTTTCGGTGGCCGGCTTCGACGACATACTCGCCGCAGCGCTGGTCACCCCGGCCCTGACGACCGTGGCGCAGT
TTCAGGATCGGCTCGGCGCCCGCGCCGCGGAAAAGCTGATCAAGCGCCTGGCTGGCGAGCCTACGGCCCCGGGCCAGGCG
GAGGAAATGGCCTACGAACTTATCATCCGCGCTTCGGTCGCACCGTTTACGGCGCGGCCGGACCAAACGCATCGAACAGG
GGAGGAAATATCATGA

Upstream 100 bases:

>100_bases
AAAGCTGACATTTAACGAGAGCAGACTGGCCTGAAAGGCGCCAGGTTGACTCCGTTGTTACGTATCAGTATCCATTGCTA
CGTAGCAAAAAAGAGATCGG

Downstream 100 bases:

>100_bases
TCAGGCTGAAGCTTTTGGCAGCCACCGCATTGATCGCCGGCACCGCGCAGATGGCCGCCGCACAGGAAAAGGTATCCTGG
TGGTATGAGCAGGCGACGCC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Degradation activator [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MSQRATQKQVAERAGVAQATVSLVLNGGRDKVAPETAERIEAAISELGYQPNRFAQALRTKRTHVIACVVPDLTNPFYPS
LVVAVQKIARAAGYEVVTIDTEGELANELQVILAAQQGRFDGVVGVFFKANARDLAPLGKSGVPVVRIEVSRKAGGPLPI
DDLFIDNVAAARALTLHLLELGHRSIAMIAAPGGPQQVRLQGYLEAMATIGAEPIVLEAAHFTLEAGREVADRLIESGRS
VSAIIAANDLMAIGVMQGLAANGLSVPGDVSVAGFDDILAAALVTPALTTVAQFQDRLGARAAEKLIKRLAGEPTAPGQA
EEMAYELIIRASVAPFTARPDQTHRTGEEIS

Sequences:

>Translated_351_residues
MSQRATQKQVAERAGVAQATVSLVLNGGRDKVAPETAERIEAAISELGYQPNRFAQALRTKRTHVIACVVPDLTNPFYPS
LVVAVQKIARAAGYEVVTIDTEGELANELQVILAAQQGRFDGVVGVFFKANARDLAPLGKSGVPVVRIEVSRKAGGPLPI
DDLFIDNVAAARALTLHLLELGHRSIAMIAAPGGPQQVRLQGYLEAMATIGAEPIVLEAAHFTLEAGREVADRLIESGRS
VSAIIAANDLMAIGVMQGLAANGLSVPGDVSVAGFDDILAAALVTPALTTVAQFQDRLGARAAEKLIKRLAGEPTAPGQA
EEMAYELIIRASVAPFTARPDQTHRTGEEIS
>Mature_350_residues
SQRATQKQVAERAGVAQATVSLVLNGGRDKVAPETAERIEAAISELGYQPNRFAQALRTKRTHVIACVVPDLTNPFYPSL
VVAVQKIARAAGYEVVTIDTEGELANELQVILAAQQGRFDGVVGVFFKANARDLAPLGKSGVPVVRIEVSRKAGGPLPID
DLFIDNVAAARALTLHLLELGHRSIAMIAAPGGPQQVRLQGYLEAMATIGAEPIVLEAAHFTLEAGREVADRLIESGRSV
SAIIAANDLMAIGVMQGLAANGLSVPGDVSVAGFDDILAAALVTPALTTVAQFQDRLGARAAEKLIKRLAGEPTAPGQAE
EMAYELIIRASVAPFTARPDQTHRTGEEIS

Specific function: Involved in the control of degradation of B.subtilis amidophosphoribosyltransferase (purF). Probably activates the gene for a degradative protease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=335, Percent_Identity=34.3283582089552, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1790369, Length=342, Percent_Identity=30.7017543859649, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787948, Length=340, Percent_Identity=30.8823529411765, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786540, Length=321, Percent_Identity=29.595015576324, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789068, Length=294, Percent_Identity=31.2925170068027, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1789202, Length=293, Percent_Identity=31.3993174061433, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI48994940, Length=320, Percent_Identity=27.1875, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788474, Length=290, Percent_Identity=31.3793103448276, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1787580, Length=317, Percent_Identity=27.4447949526814, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787906, Length=332, Percent_Identity=29.8192771084337, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1790715, Length=315, Percent_Identity=22.5396825396825, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1786268, Length=321, Percent_Identity=25.8566978193146, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790689, Length=321, Percent_Identity=24.9221183800623, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1790192, Length=265, Percent_Identity=29.4339622641509, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36959; Mature: 36828

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQRATQKQVAERAGVAQATVSLVLNGGRDKVAPETAERIEAAISELGYQPNRFAQALRT
CCCCHHHHHHHHHHCHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
KRTHVIACVVPDLTNPFYPSLVVAVQKIARAAGYEVVTIDTEGELANELQVILAAQQGRF
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCC
DGVVGVFFKANARDLAPLGKSGVPVVRIEVSRKAGGPLPIDDLFIDNVAAARALTLHLLE
CCEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LGHRSIAMIAAPGGPQQVRLQGYLEAMATIGAEPIVLEAAHFTLEAGREVADRLIESGRS
HCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCC
VSAIIAANDLMAIGVMQGLAANGLSVPGDVSVAGFDDILAAALVTPALTTVAQFQDRLGA
EEEEEEHHHHHHHHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCH
RAAEKLIKRLAGEPTAPGQAEEMAYELIIRASVAPFTARPDQTHRTGEEIS
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SQRATQKQVAERAGVAQATVSLVLNGGRDKVAPETAERIEAAISELGYQPNRFAQALRT
CCCHHHHHHHHHHCHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
KRTHVIACVVPDLTNPFYPSLVVAVQKIARAAGYEVVTIDTEGELANELQVILAAQQGRF
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCC
DGVVGVFFKANARDLAPLGKSGVPVVRIEVSRKAGGPLPIDDLFIDNVAAARALTLHLLE
CCEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LGHRSIAMIAAPGGPQQVRLQGYLEAMATIGAEPIVLEAAHFTLEAGREVADRLIESGRS
HCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCC
VSAIIAANDLMAIGVMQGLAANGLSVPGDVSVAGFDDILAAALVTPALTTVAQFQDRLGA
EEEEEEHHHHHHHHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCH
RAAEKLIKRLAGEPTAPGQAEEMAYELIIRASVAPFTARPDQTHRTGEEIS
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407808; 9353932; 9384377 [H]