Click here to switch to the map view.

The map label for this gene is malE [C]

Identifier: 110633448

GI number: 110633448

Start: 1199894

End: 1201198

Strand: Direct

Name: malE [C]

Synonym: Meso_1094

Alternate gene names: 110633448

Gene position: 1199894-1201198 (Clockwise)

Preceding gene: 110633447

Following gene: 110633449

Centisome position: 27.19

GC content: 59.46

Gene sequence:

>1305_bases
ATGATCAGGCTGAAGCTTTTGGCAGCCACCGCATTGATCGCCGGCACCGCGCAGATGGCCGCCGCACAGGAAAAGGTATC
CTGGTGGTATGAGCAGGCGACGCCGGACCAGCAGAAGCTGATCCAGCAGCACATCGTCGAGCCCTTCGCAAAGGCGAACC
CGGACTACAACCTTGTCATCGATTATCGCGGCAACGAGCTGGACAAGCAGTTGCGGGTCGCGATGCTGTCTGGCAACGGC
CCTGACGTCGTCTATACCGCTGGCCCGAGCTATGTGGCGCCGATGGCCCAGTCCGGCCAGCTGATGCCGCTCGACGACTA
TGCCGCGAAGTACAAATGGCAAGACCGAATCCTTCCGGTCTTCCTGAAGATGGGCGAATATAACGGCAAGATCTACGCGC
TCCCCAAGACCTACGAGACGCTCGGCCTGTTCTACAACAAAACGCTTTTTGCCCAGAAGAACTGGCAACCGCCGAAGACG
CTCGACGAGCTGGAAACCCTGGCCGACGCCATGCTGAAGGATGGCATTACGCCATTTGCCGCTGGCAACGCCAATTGGCG
CGGCGCCAACGAATGGTTTGTGACGCTAGCGCTCAACTCGGTCGCCGGCCCCGAAAATCTCAACAAGGCCCTGCGTGGCG
AGATGCCCTGGACGTCCGAGCCTTTCGTCAAGGCGATCGACCGGCTGAATTCCTGGTGGCAGAAGGGCTATTTCGGCAAA
AATTACTTCTCGCTCACGAGCAGCGAAGATACCGCCGATGCTATGGCCACAGGCAGGGCCGGCATGATGCCGACCGGCAC
CTGGCAATTCCAGAATGTCGCTACTTACGGTAAGAAGGCAGGCAGCGATGCCGGCTTCGTTGGTTTCCCGAGCGCTTCGG
GCGATCCGGTTTTCCCGCTCGGCATCGGCTCGACCTTTTCAATCGCCGCAAAGGCCAAAAATCCGGACGGCGCCGCTGCC
GCCATCAACTTTGTTTTCTCGCCCGAGGTTTACGGCACGATGAACTCGGCCTGGCAGGGTGAGTGGAACATCCCGCTGAA
GGACATCTCCAACGTCAAGATGGCGAGCGAAGTCACGCCGCTGTTCACGGAGACGATGAAGAGCCTCTCAGCCGCCGTGA
ATGACGGCAAATACGGCTACTCGACCTGGACCTTCCTGCCGCCGGCGACCGACAGCTATCTCATCAACGGCATCGAAGAG
GTCTGGCTGAACAAGATCACGACTGCCGATTTCCTCGCCAAGATAGACGAGTCCTTCCAGAAGGAAATGAAAGCCGGCAA
GACTCCCGCCGTTCCGGCCCGCTGA

Upstream 100 bases:

>100_bases
GCCAGGCGGAGGAAATGGCCTACGAACTTATCATCCGCGCTTCGGTCGCACCGTTTACGGCGCGGCCGGACCAAACGCAT
CGAACAGGGGAGGAAATATC

Downstream 100 bases:

>100_bases
TCCGCAGATCTTAGGGGCCTGGCCTGCCCAGGCCCCCACATTCCCGCTTTTCCTGGTGGCGCAGGGCGCTCGACGCCTTG
AAAGGTACGCTATGCACCGA

Product: extracellular solute-binding protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MIRLKLLAATALIAGTAQMAAAQEKVSWWYEQATPDQQKLIQQHIVEPFAKANPDYNLVIDYRGNELDKQLRVAMLSGNG
PDVVYTAGPSYVAPMAQSGQLMPLDDYAAKYKWQDRILPVFLKMGEYNGKIYALPKTYETLGLFYNKTLFAQKNWQPPKT
LDELETLADAMLKDGITPFAAGNANWRGANEWFVTLALNSVAGPENLNKALRGEMPWTSEPFVKAIDRLNSWWQKGYFGK
NYFSLTSSEDTADAMATGRAGMMPTGTWQFQNVATYGKKAGSDAGFVGFPSASGDPVFPLGIGSTFSIAAKAKNPDGAAA
AINFVFSPEVYGTMNSAWQGEWNIPLKDISNVKMASEVTPLFTETMKSLSAAVNDGKYGYSTWTFLPPATDSYLINGIEE
VWLNKITTADFLAKIDESFQKEMKAGKTPAVPAR

Sequences:

>Translated_434_residues
MIRLKLLAATALIAGTAQMAAAQEKVSWWYEQATPDQQKLIQQHIVEPFAKANPDYNLVIDYRGNELDKQLRVAMLSGNG
PDVVYTAGPSYVAPMAQSGQLMPLDDYAAKYKWQDRILPVFLKMGEYNGKIYALPKTYETLGLFYNKTLFAQKNWQPPKT
LDELETLADAMLKDGITPFAAGNANWRGANEWFVTLALNSVAGPENLNKALRGEMPWTSEPFVKAIDRLNSWWQKGYFGK
NYFSLTSSEDTADAMATGRAGMMPTGTWQFQNVATYGKKAGSDAGFVGFPSASGDPVFPLGIGSTFSIAAKAKNPDGAAA
AINFVFSPEVYGTMNSAWQGEWNIPLKDISNVKMASEVTPLFTETMKSLSAAVNDGKYGYSTWTFLPPATDSYLINGIEE
VWLNKITTADFLAKIDESFQKEMKAGKTPAVPAR
>Mature_434_residues
MIRLKLLAATALIAGTAQMAAAQEKVSWWYEQATPDQQKLIQQHIVEPFAKANPDYNLVIDYRGNELDKQLRVAMLSGNG
PDVVYTAGPSYVAPMAQSGQLMPLDDYAAKYKWQDRILPVFLKMGEYNGKIYALPKTYETLGLFYNKTLFAQKNWQPPKT
LDELETLADAMLKDGITPFAAGNANWRGANEWFVTLALNSVAGPENLNKALRGEMPWTSEPFVKAIDRLNSWWQKGYFGK
NYFSLTSSEDTADAMATGRAGMMPTGTWQFQNVATYGKKAGSDAGFVGFPSASGDPVFPLGIGSTFSIAAKAKNPDGAAA
AINFVFSPEVYGTMNSAWQGEWNIPLKDISNVKMASEVTPLFTETMKSLSAAVNDGKYGYSTWTFLPPATDSYLINGIEE
VWLNKITTADFLAKIDESFQKEMKAGKTPAVPAR

Specific function: Probably part of a binding-protein-dependent transport system PH1214/15/16 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 720 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 47723; Mature: 47723

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLKLLAATALIAGTAQMAAAQEKVSWWYEQATPDQQKLIQQHIVEPFAKANPDYNLVI
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEE
DYRGNELDKQLRVAMLSGNGPDVVYTAGPSYVAPMAQSGQLMPLDDYAAKYKWQDRILPV
EECCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHCCHHCCCEEE
FLKMGEYNGKIYALPKTYETLGLFYNKTLFAQKNWQPPKTLDELETLADAMLKDGITPFA
HEEECCCCCEEEECCCHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCC
AGNANWRGANEWFVTLALNSVAGPENLNKALRGEMPWTSEPFVKAIDRLNSWWQKGYFGK
CCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
NYFSLTSSEDTADAMATGRAGMMPTGTWQFQNVATYGKKAGSDAGFVGFPSASGDPVFPL
CEEEECCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEECCCCCCCEEEEE
GIGSTFSIAAKAKNPDGAAAAINFVFSPEVYGTMNSAWQGEWNIPLKDISNVKMASEVTP
CCCCCEEEEEECCCCCCCEEEEEEEECCCHHCCCCCCCCCCCCCCHHHHCCCHHHHHCCH
LFTETMKSLSAAVNDGKYGYSTWTFLPPATDSYLINGIEEVWLNKITTADFLAKIDESFQ
HHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEMKAGKTPAVPAR
HHHHCCCCCCCCCC
>Mature Secondary Structure
MIRLKLLAATALIAGTAQMAAAQEKVSWWYEQATPDQQKLIQQHIVEPFAKANPDYNLVI
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEE
DYRGNELDKQLRVAMLSGNGPDVVYTAGPSYVAPMAQSGQLMPLDDYAAKYKWQDRILPV
EECCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHCCHHCCCEEE
FLKMGEYNGKIYALPKTYETLGLFYNKTLFAQKNWQPPKTLDELETLADAMLKDGITPFA
HEEECCCCCEEEECCCHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCC
AGNANWRGANEWFVTLALNSVAGPENLNKALRGEMPWTSEPFVKAIDRLNSWWQKGYFGK
CCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
NYFSLTSSEDTADAMATGRAGMMPTGTWQFQNVATYGKKAGSDAGFVGFPSASGDPVFPL
CEEEECCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEECCCCCCCEEEEE
GIGSTFSIAAKAKNPDGAAAAINFVFSPEVYGTMNSAWQGEWNIPLKDISNVKMASEVTP
CCCCCEEEEEECCCCCCCEEEEEEEECCCHHCCCCCCCCCCCCCCHHHHCCCHHHHHCCH
LFTETMKSLSAAVNDGKYGYSTWTFLPPATDSYLINGIEEVWLNKITTADFLAKIDESFQ
HHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEMKAGKTPAVPAR
HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]