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The map label for this gene is ade

Identifier: 110633436

GI number: 110633436

Start: 1186006

End: 1187808

Strand: Reverse

Name: ade

Synonym: Meso_1082

Alternate gene names: 110633436

Gene position: 1187808-1186006 (Counterclockwise)

Preceding gene: 110633438

Following gene: 110633432

Centisome position: 26.92

GC content: 63.17

Gene sequence:

>1803_bases
ATGAGCACCCTCACCCGCTTTTCCGTGCGCCCGCTGGCAACCATGACACGGCATCTTGCCGATGTGGCTTCCGGCCGCGC
AGAACCCGACCTCGTCATCAAGGGCGCACGGGTGCTCTCCACCTATTCCGAGCGTATCCTGCCGGATCGCGAAGTGTGGA
TCTCGGGCGGGCGAATCGCTGCGGTAAAGCCCGCGGGCAGCTATCGCGGCAGCGCGGCGACCATTTACGACGCGGCGGGC
GGACTGATCGCGCCGGGGCTGGTGGACCCGCACATTCATATCGAATCAAGCATGGTCACCGCCTGCTCCTATGCGGAGGC
GGCCCTTCTCAACGGCACCACCACGATCTTCTGCGACAGCCACGAAATCGGCAATGTCATGGATGTGGCGGGAGTCGAGG
CAATGCTTGAGGATGCCCGCCAGGCACCATCGTCGATTTTCCTTACCGTTCCGAGCACGGTCCCCGCAACGTCTCCCGAA
CTTGAAACGGCAGGCGGCGACCTCACGGCCGAAAAGATCGCAGCCCTATTCGACAAATGGCCGGAGGCCGTTGCGCTGGG
CGAAAAAATGGATTTCGTGCAGGTTGCCATGGGTGACGAACGCAGCCATGCAATCCTGGCCGCGGCGCTGGAGCGCGGGC
GCCCAGTGTCCGGCCATGTCTATGGCCGGGAGTTCGTCGCAGCCTATGCTGCCTCGGGCGTGACCGACACGCATGAGGCG
ATCGATCGCGAGATCGCGGACGACCTGCTCGAAGCCGGCATCTGGCTTTTCCTGCGCGGCGGGCCGCCCACGACGCCTTG
GCACAGCCTGCCGCAGGCCATCAAGACCATCACGGAGCTTGGCGCCTCGCACAAGCGCATTGCGGTCTGCACCGACGACA
GGGACGCGGACGACCTGCTGCTCTTCGGCCTCGATTGGGTGACGCGCGAGGCGATGAAGGCGGGGATGAAACCCGAACAG
GCCTGGGCAATGGGTTCTTTGCACGGGGCGACACGCTTTGGCCTGGAGGGCGATATCGGCGGCCTTGGAGGCGGGCGGCG
GGCTGATCTCGTGCTCCTCGACGACGGCTTTAAGCCCGTCAACACCTGGTATGGCGGCGAGCTCGTGGTTGAGAACAGGA
AGATCACGCCTCTGCTCGATACCGCTCTTTCCAACCGCTACCGCTATCCGGAAGCGGCCTATCACACGGTCAAACTGCCG
AAGGCCGTGAAGCTTACGCCGGAACTTCCTACGGCAAGAGTCGTCGCCCATACGATCCGCACCGAGCTTCCCGGCATCAC
GCTCGGCCACGAGCGGATCACGCTGGAGCCTTCGAACCACTGGCAGGATCATTTCGACCGGCACGGGCTCTGCTTTGTGG
CCGTTGTCGAACGGCACGGAAAGTCAGCCGGCAATGTCGCTCACGGGCTCTTGAGCAATTTCAACCTGAAGCGCGGCGCC
GTCGCCTCCTCTGTCGGCCATGACAGCCACAACATCATCGTGGCCGGAACCAACGAGGCGGACATGCAGGTGGCGCTGCG
CGCCATCGAGGAGGCGCAAGGCGGCGTCTGCGTGGTCATGGATGGAAAGGTGACTGCGATGGTGCCCCTGCCCATCGCCG
GTCTCCTGTCTGACAAGCGGGTGACGGAAGTGGCGGAGGAGGTGAAAGCCTTGAAGGTTGAGTGGGAGAAGGCAGGCTGC
TCCATCCCCTATATGGGCTTCAACCTCATCCCGCTTTCAGTAATCCCGGAAATCCGCATTACGGACAAAGGGCTCGTCCT
CGTGCCTGAAATGGAGATCGTGCAACTTTTCGAAGCGGCTTGA

Upstream 100 bases:

>100_bases
CCGCCGAAGAAGGCGCAGGTGAATTTGGACGCCGCTTGATCCGTCGCCGCGCCAGGGTCATTCTGCAAGGAAGCATGTGT
CTCCATATCCGAGGTCATCC

Downstream 100 bases:

>100_bases
GCAATAGATGCGAGATAGGCTAGGTCCGGCATTTCGGCCCTTACACAGCCTGGCTTTCTGCAACGAACTTCGCCAAGGCG
AGAGAGGATGTCAGGCCGGG

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase

Number of amino acids: Translated: 600; Mature: 599

Protein sequence:

>600_residues
MSTLTRFSVRPLATMTRHLADVASGRAEPDLVIKGARVLSTYSERILPDREVWISGGRIAAVKPAGSYRGSAATIYDAAG
GLIAPGLVDPHIHIESSMVTACSYAEAALLNGTTTIFCDSHEIGNVMDVAGVEAMLEDARQAPSSIFLTVPSTVPATSPE
LETAGGDLTAEKIAALFDKWPEAVALGEKMDFVQVAMGDERSHAILAAALERGRPVSGHVYGREFVAAYAASGVTDTHEA
IDREIADDLLEAGIWLFLRGGPPTTPWHSLPQAIKTITELGASHKRIAVCTDDRDADDLLLFGLDWVTREAMKAGMKPEQ
AWAMGSLHGATRFGLEGDIGGLGGGRRADLVLLDDGFKPVNTWYGGELVVENRKITPLLDTALSNRYRYPEAAYHTVKLP
KAVKLTPELPTARVVAHTIRTELPGITLGHERITLEPSNHWQDHFDRHGLCFVAVVERHGKSAGNVAHGLLSNFNLKRGA
VASSVGHDSHNIIVAGTNEADMQVALRAIEEAQGGVCVVMDGKVTAMVPLPIAGLLSDKRVTEVAEEVKALKVEWEKAGC
SIPYMGFNLIPLSVIPEIRITDKGLVLVPEMEIVQLFEAA

Sequences:

>Translated_600_residues
MSTLTRFSVRPLATMTRHLADVASGRAEPDLVIKGARVLSTYSERILPDREVWISGGRIAAVKPAGSYRGSAATIYDAAG
GLIAPGLVDPHIHIESSMVTACSYAEAALLNGTTTIFCDSHEIGNVMDVAGVEAMLEDARQAPSSIFLTVPSTVPATSPE
LETAGGDLTAEKIAALFDKWPEAVALGEKMDFVQVAMGDERSHAILAAALERGRPVSGHVYGREFVAAYAASGVTDTHEA
IDREIADDLLEAGIWLFLRGGPPTTPWHSLPQAIKTITELGASHKRIAVCTDDRDADDLLLFGLDWVTREAMKAGMKPEQ
AWAMGSLHGATRFGLEGDIGGLGGGRRADLVLLDDGFKPVNTWYGGELVVENRKITPLLDTALSNRYRYPEAAYHTVKLP
KAVKLTPELPTARVVAHTIRTELPGITLGHERITLEPSNHWQDHFDRHGLCFVAVVERHGKSAGNVAHGLLSNFNLKRGA
VASSVGHDSHNIIVAGTNEADMQVALRAIEEAQGGVCVVMDGKVTAMVPLPIAGLLSDKRVTEVAEEVKALKVEWEKAGC
SIPYMGFNLIPLSVIPEIRITDKGLVLVPEMEIVQLFEAA
>Mature_599_residues
STLTRFSVRPLATMTRHLADVASGRAEPDLVIKGARVLSTYSERILPDREVWISGGRIAAVKPAGSYRGSAATIYDAAGG
LIAPGLVDPHIHIESSMVTACSYAEAALLNGTTTIFCDSHEIGNVMDVAGVEAMLEDARQAPSSIFLTVPSTVPATSPEL
ETAGGDLTAEKIAALFDKWPEAVALGEKMDFVQVAMGDERSHAILAAALERGRPVSGHVYGREFVAAYAASGVTDTHEAI
DREIADDLLEAGIWLFLRGGPPTTPWHSLPQAIKTITELGASHKRIAVCTDDRDADDLLLFGLDWVTREAMKAGMKPEQA
WAMGSLHGATRFGLEGDIGGLGGGRRADLVLLDDGFKPVNTWYGGELVVENRKITPLLDTALSNRYRYPEAAYHTVKLPK
AVKLTPELPTARVVAHTIRTELPGITLGHERITLEPSNHWQDHFDRHGLCFVAVVERHGKSAGNVAHGLLSNFNLKRGAV
ASSVGHDSHNIIVAGTNEADMQVALRAIEEAQGGVCVVMDGKVTAMVPLPIAGLLSDKRVTEVAEEVKALKVEWEKAGCS
IPYMGFNLIPLSVIPEIRITDKGLVLVPEMEIVQLFEAA

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=593, Percent_Identity=30.8600337268128, Blast_Score=207, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC_MESSB (Q11JE6)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_673644.1
- ProteinModelPortal:   Q11JE6
- STRING:   Q11JE6
- GeneID:   4181242
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_1082
- NMPDR:   fig|266779.1.peg.2499
- eggNOG:   COG1001
- HOGENOM:   HBG725357
- OMA:   DSHEIGN
- PhylomeDB:   Q11JE6
- ProtClustDB:   CLSK910980
- BioCyc:   MSP266779:MESO_1082-MONOMER
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 64391; Mature: 64260

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLTRFSVRPLATMTRHLADVASGRAEPDLVIKGARVLSTYSERILPDREVWISGGRIA
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHCCCCCCEEEECCEEE
AVKPAGSYRGSAATIYDAAGGLIAPGLVDPHIHIESSMVTACSYAEAALLNGTTTIFCDS
EECCCCCCCCCEEEEEECCCCEECCCCCCCCEEECCHHHHHHHHHHHHHCCCCEEEEECC
HEIGNVMDVAGVEAMLEDARQAPSSIFLTVPSTVPATSPELETAGGDLTAEKIAALFDKW
CCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
PEAVALGEKMDFVQVAMGDERSHAILAAALERGRPVSGHVYGREFVAAYAASGVTDTHEA
HHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEECHHHHHHHHHHCCCCHHHHH
IDREIADDLLEAGIWLFLRGGPPTTPWHSLPQAIKTITELGASHKRIAVCTDDRDADDLL
HHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEE
LFGLDWVTREAMKAGMKPEQAWAMGSLHGATRFGLEGDIGGLGGGRRADLVLLDDGFKPV
EECHHHHHHHHHHCCCCHHHHHHHHCCCCCEECCCCCCCCCCCCCCEEEEEEEECCCCCC
NTWYGGELVVENRKITPLLDTALSNRYRYPEAAYHTVKLPKAVKLTPELPTARVVAHTIR
CCCCCCEEEEECCCCCHHHHHHHHCCCCCCCHHEEEEECCCEEEECCCCCHHHHHHHHHH
TELPGITLGHERITLEPSNHWQDHFDRHGLCFVAVVERHGKSAGNVAHGLLSNFNLKRGA
HCCCCEEECCCEEEECCCCCCHHHHCCCCEEEEEEEHHCCCCCCHHHHHHHHCCCCCCCC
VASSVGHDSHNIIVAGTNEADMQVALRAIEEAQGGVCVVMDGKVTAMVPLPIAGLLSDKR
HHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCHHHHHCCHH
VTEVAEEVKALKVEWEKAGCSIPYMGFNLIPLSVIPEIRITDKGLVLVPEMEIVQLFEAA
HHHHHHHHHHHEEEHHHCCCCCCCCCCEEEEHHHCCCEEECCCCEEEECCHHHHHHHHCC
>Mature Secondary Structure 
STLTRFSVRPLATMTRHLADVASGRAEPDLVIKGARVLSTYSERILPDREVWISGGRIA
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHCCCCCCEEEECCEEE
AVKPAGSYRGSAATIYDAAGGLIAPGLVDPHIHIESSMVTACSYAEAALLNGTTTIFCDS
EECCCCCCCCCEEEEEECCCCEECCCCCCCCEEECCHHHHHHHHHHHHHCCCCEEEEECC
HEIGNVMDVAGVEAMLEDARQAPSSIFLTVPSTVPATSPELETAGGDLTAEKIAALFDKW
CCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHC
PEAVALGEKMDFVQVAMGDERSHAILAAALERGRPVSGHVYGREFVAAYAASGVTDTHEA
HHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEECHHHHHHHHHHCCCCHHHHH
IDREIADDLLEAGIWLFLRGGPPTTPWHSLPQAIKTITELGASHKRIAVCTDDRDADDLL
HHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEE
LFGLDWVTREAMKAGMKPEQAWAMGSLHGATRFGLEGDIGGLGGGRRADLVLLDDGFKPV
EECHHHHHHHHHHCCCCHHHHHHHHCCCCCEECCCCCCCCCCCCCCEEEEEEEECCCCCC
NTWYGGELVVENRKITPLLDTALSNRYRYPEAAYHTVKLPKAVKLTPELPTARVVAHTIR
CCCCCCEEEEECCCCCHHHHHHHHCCCCCCCHHEEEEECCCEEEECCCCCHHHHHHHHHH
TELPGITLGHERITLEPSNHWQDHFDRHGLCFVAVVERHGKSAGNVAHGLLSNFNLKRGA
HCCCCEEECCCEEEECCCCCCHHHHCCCCEEEEEEEHHCCCCCCHHHHHHHHCCCCCCCC
VASSVGHDSHNIIVAGTNEADMQVALRAIEEAQGGVCVVMDGKVTAMVPLPIAGLLSDKR
HHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCHHHHHCCHH
VTEVAEEVKALKVEWEKAGCSIPYMGFNLIPLSVIPEIRITDKGLVLVPEMEIVQLFEAA
HHHHHHHHHHHEEEHHHCCCCCCCCCCEEEEHHHCCCEEECCCCEEEECCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA