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The map label for this gene is yitF [H]

Identifier: 110633425

GI number: 110633425

Start: 1174510

End: 1175619

Strand: Reverse

Name: yitF [H]

Synonym: Meso_1071

Alternate gene names: 110633425

Gene position: 1175619-1174510 (Counterclockwise)

Preceding gene: 110633430

Following gene: 110633424

Centisome position: 26.64

GC content: 61.44

Gene sequence:

>1110_bases
ATGAAGATCACCGACGTCACGATCACCATGTTCGAGAAGCCGATCCCCCCGGCTTCGTACGGGCGGCACACCCTGCCCGG
ATCCGGCAAGCTGACAATGGGTTTGCTGAAGGTCTCGACCGATGAGGGGGTCGACGGCCATGCCTTCCTCGGATCGCCCG
TGCGCACCGCGGAACTCGACGCCGCCTCGCTTATCATCGCGCTCAAGCCCGTCGTGGTCGGGCGCGACCCGCTCCAGCGC
GAAGCAATTTACAAGGATCTCGCCCGCCGCGCGGGACTTTCCACCTGGCGCTGCGTCGGCGCCATCGACGTGGCGTTGTG
GGACATCGCAGGCAAGGTGGCGGGGCTGCCGATTTATCAGCTGATCGGCGGCTTCAGGGAAAAGGCGCCGGCTTATGCCA
GTTCGCCCGGCTGGGCGGAGGTGGAGCAATATGTCGAAGAAGCCCAGACGGTGAAGGCACATGGCTACGCCGCCTATAAA
GTGCATCCGCCTCGCCTCGGCTGGGAAATGGATTTGAAAGTTGCCCGCGCGGTGCGCCGGGTGGTCGGCGACCACTATCG
GCTGATGTTCGATTCGACCGGCGTCTACACCTATGCCGAAGCACTGAAGGTGGGGAGGGAGCTGGAGGAACTCGGCTACT
ACTGGTTCGAGGACCCCCTCCCCTTCGAAGACATCTACAACTACACCAAGCTCAAGCAGAAGCTCGAAATCCAGATCATG
GCGACCGAGCTTTCACCCGGCGCGTTCCATGCTTACGAGCCATGGGTATCGCAAAAGGCGACAGATGCGCTGCGCGGCGA
CGTAGCATTGAAGGGCGGCATCACCGCCTGCCTCAAGACAGCGCATCTCGCCGAAGCCTTCCGCCTCAATTACGAGCTGC
ATCACGGCGGGAATTCGCTCAACAATGTCGCAAACCTGCATGTCTTCTGCGCCATCCCCAACACGGAATTTTTCGAGGTC
GTGTTGCCGGACGAAGCGCAGAAGTGCGGGCTGGTCGTGGATCTTTCCGTCGGCTCTGACGGCTTCGTCCATGTGCCGAA
GGGGCCGGGACTCGGCGCCGAGATCGACTTCGATCTGATCGAAAAATCAAAGATCGGGCTGCTTTCCTGA

Upstream 100 bases:

>100_bases
TCGCGGAACCTCCTCCAAAGGCTCCGGTCAATTGCTTTTGTATACAGAAATATGCAAGGATATGCAAATAGGTTTCAGGA
GGGTTTCTGAGGAGGAGCGC

Downstream 100 bases:

>100_bases
GCTGGACGCGCACCCGAACAAAGGAGAGGGAACGTGGCGGACAATATCGCGGATGAAATCCTGGAGGCTGAGGCCACCCG
CTGCAACGCGCTTACGAATG

Product: mandelate racemase/muconate lactonizing-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MKITDVTITMFEKPIPPASYGRHTLPGSGKLTMGLLKVSTDEGVDGHAFLGSPVRTAELDAASLIIALKPVVVGRDPLQR
EAIYKDLARRAGLSTWRCVGAIDVALWDIAGKVAGLPIYQLIGGFREKAPAYASSPGWAEVEQYVEEAQTVKAHGYAAYK
VHPPRLGWEMDLKVARAVRRVVGDHYRLMFDSTGVYTYAEALKVGRELEELGYYWFEDPLPFEDIYNYTKLKQKLEIQIM
ATELSPGAFHAYEPWVSQKATDALRGDVALKGGITACLKTAHLAEAFRLNYELHHGGNSLNNVANLHVFCAIPNTEFFEV
VLPDEAQKCGLVVDLSVGSDGFVHVPKGPGLGAEIDFDLIEKSKIGLLS

Sequences:

>Translated_369_residues
MKITDVTITMFEKPIPPASYGRHTLPGSGKLTMGLLKVSTDEGVDGHAFLGSPVRTAELDAASLIIALKPVVVGRDPLQR
EAIYKDLARRAGLSTWRCVGAIDVALWDIAGKVAGLPIYQLIGGFREKAPAYASSPGWAEVEQYVEEAQTVKAHGYAAYK
VHPPRLGWEMDLKVARAVRRVVGDHYRLMFDSTGVYTYAEALKVGRELEELGYYWFEDPLPFEDIYNYTKLKQKLEIQIM
ATELSPGAFHAYEPWVSQKATDALRGDVALKGGITACLKTAHLAEAFRLNYELHHGGNSLNNVANLHVFCAIPNTEFFEV
VLPDEAQKCGLVVDLSVGSDGFVHVPKGPGLGAEIDFDLIEKSKIGLLS
>Mature_369_residues
MKITDVTITMFEKPIPPASYGRHTLPGSGKLTMGLLKVSTDEGVDGHAFLGSPVRTAELDAASLIIALKPVVVGRDPLQR
EAIYKDLARRAGLSTWRCVGAIDVALWDIAGKVAGLPIYQLIGGFREKAPAYASSPGWAEVEQYVEEAQTVKAHGYAAYK
VHPPRLGWEMDLKVARAVRRVVGDHYRLMFDSTGVYTYAEALKVGRELEELGYYWFEDPLPFEDIYNYTKLKQKLEIQIM
ATELSPGAFHAYEPWVSQKATDALRGDVALKGGITACLKTAHLAEAFRLNYELHHGGNSLNNVANLHVFCAIPNTEFFEV
VLPDEAQKCGLVVDLSVGSDGFVHVPKGPGLGAEIDFDLIEKSKIGLLS

Specific function: Probably Involved In The Degradation Of Homoserine Lactone (Hsl) Or Of A Metabolite Of Hsl That Signals Starvation. [C]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1787864, Length=383, Percent_Identity=26.8929503916449, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994953, Length=353, Percent_Identity=28.0453257790368, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI226510960, Length=270, Percent_Identity=25.5555555555556, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015654
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: NA

Molecular weight: Translated: 40459; Mature: 40459

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITDVTITMFEKPIPPASYGRHTLPGSGKLTMGLLKVSTDEGVDGHAFLGSPVRTAELD
CEEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCEECCCCCCCCCCC
AASLIIALKPVVVGRDPLQREAIYKDLARRAGLSTWRCVGAIDVALWDIAGKVAGLPIYQ
HHEEEEEEECEEECCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCHHH
LIGGFREKAPAYASSPGWAEVEQYVEEAQTVKAHGYAAYKVHPPRLGWEMDLKVARAVRR
HHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHH
VVGDHYRLMFDSTGVYTYAEALKVGRELEELGYYWFEDPLPFEDIYNYTKLKQKLEIQIM
HHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHEEEEEEE
ATELSPGAFHAYEPWVSQKATDALRGDVALKGGITACLKTAHLAEAFRLNYELHHGGNSL
EEECCCCCCCCCCCHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHEEEEEECCCCCC
NNVANLHVFCAIPNTEFFEVVLPDEAQKCGLVVDLSVGSDGFVHVPKGPGLGAEIDFDLI
CCCEEEEEEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCEEECCCCCCCCCEEEHHHH
EKSKIGLLS
CCCCCCCCC
>Mature Secondary Structure
MKITDVTITMFEKPIPPASYGRHTLPGSGKLTMGLLKVSTDEGVDGHAFLGSPVRTAELD
CEEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCEECCCCCCCCCCC
AASLIIALKPVVVGRDPLQREAIYKDLARRAGLSTWRCVGAIDVALWDIAGKVAGLPIYQ
HHEEEEEEECEEECCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCHHH
LIGGFREKAPAYASSPGWAEVEQYVEEAQTVKAHGYAAYKVHPPRLGWEMDLKVARAVRR
HHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHH
VVGDHYRLMFDSTGVYTYAEALKVGRELEELGYYWFEDPLPFEDIYNYTKLKQKLEIQIM
HHCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHEEEEEEE
ATELSPGAFHAYEPWVSQKATDALRGDVALKGGITACLKTAHLAEAFRLNYELHHGGNSL
EEECCCCCCCCCCCHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHEEEEEECCCCCC
NNVANLHVFCAIPNTEFFEVVLPDEAQKCGLVVDLSVGSDGFVHVPKGPGLGAEIDFDLI
CCCEEEEEEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCEEECCCCCCCCCEEEHHHH
EKSKIGLLS
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]