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The map label for this gene is 110633391

Identifier: 110633391

GI number: 110633391

Start: 1139261

End: 1140928

Strand: Direct

Name: 110633391

Synonym: Meso_1037

Alternate gene names: NA

Gene position: 1139261-1140928 (Clockwise)

Preceding gene: 110633390

Following gene: 110633392

Centisome position: 25.82

GC content: 63.61

Gene sequence:

>1668_bases
GTGGCGTCCGACGAAGCGGAACTGGTTTTTTGCCCTTTGGGTGGTGTCGGCGAGATCGGCATGAATTTGGCCCTCTATGG
TTACGGGCCGCGCGACAATCGCACCTGGATCATGATCGATTGCGGTGTGAGCTTTCCAGGCGAGAACCTGCCGGGCGTCG
ATCTCATTCTTCCGGATGTCAGCTTCATCGAGGACCAGCTTGAAAATCTCGCGGGCATAATCATCACCCACGCGCATGAG
GACCATTACGGCGCGTTGCTGGACCTTTGGCCGCGCCTCAAGACCAATGTGTGGATGACGCCGTTCACGGCAGGCCTTCT
CGAGGCCAAACGGCAGGGTGAGGTGAACGCGCCGAAAGTGCCGGTGACGATCTACAAGGCCGGCGAGACCTTCACCGTCG
GCCCCTTCGCCATCGAGGCGATCGCCGTCGCCCACTCGATCCCCGAGCCTGTCTCTCTCGCCATCACCACGCCGGCGGGA
ACGGTGATCCATACCGGCGACTGGAAGATCGATCCCGCGCCCGAACTCGGCCCCAAAACGGACGAGGCACGCTTCCGCGC
CCTGGGAGAGAAGGGCGTTCTGGCGCTCATCTGCGATTCCACCAATGCCATGCGCGAGGGTGTTTCCCCCTCGGAGCAGG
ATGTCGGCCGGGGGCTGAGGGAGGTGATCGAGAAGGCGCCGGGTCGCGTGGCCGTTACCACCTTCTCCTCCAATGTCGGG
CGCATCCGCTCGATAGCCGAAGCGGCGCGCGATGCAGGCCGGCAGGTGCTGGTGCTCGGGCGCTCGTTGCAACGCGTCAT
CGATGTCGCCGACGAGCTGGGATATCTGGACGGATTGCCACCCTTCCTCGTCGAGGAGGATTTCGGTTATATCCCGCGCG
AGAACGCGGTGATCCTCTGTACCGGCAGCCAGGGCGAAGCCCGCGCGGCATTGGCAAAGCTTGCGCGCGACGAGATGCGC
AATGTGGCGCTCTCGCCGGGTGATACGGTCATCTTTTCCTCGCGCACCATTCCGGGCAACGAAAAGGCGATCCTCACCAT
CAAAAACCAGCTGATCGAACAGGGGATCAGGGTTGTCGAGGATAGCGACGCGCTCGTTCATGTTTCCGGCCATCCGCGCC
GCAACGAATTGAAGCAGATGTATGAATGGGTAAGGCCGCGCATCCTGGTGCCCGTCCATGGCGAGGCCGCCCATCTGGTT
GCGCAGGGATCGCTCGGCGCCATGTCCGGAATCCCCGAGGTGGCCCAGGTGAGGAATGGCGGCATGCTGCGCCTGGCTCC
AGGTCCGGCCGAAATCATCGACCAGGTTCCGTTTGGCCGCATCTACCGGGACGGCAAGGTGATTGGCACGGACGATGAAG
TGGGCGTGCGCGACAGGCGCAAGCTTTCCTTTGCCGGCCATGTGGCTGTCAATGTCGTGCTCGATGACCGCTATGATCTG
GCGGGCGATCCAGATCTGGTGGCAATCGGCCTGCCGCAGGCGGACTCTGCGGGTGAGCCGATGGAGGATATCATGCTGGA
TGCCGCGGTGGGAGCCGTGCGCAGCATCCCGCGCGGCAACCGCAGGGACCTTGATCTCGTGGGCGAGGCGGTGCGGCGCG
CGGTGCGTGCGGCCGCCAGTGACGCCTGGGGCAAGAAGCCGATCGTGACGGTCTTTGTCACCCAGTAA

Upstream 100 bases:

>100_bases
TTCGTCGTAAGGGAGGATAATGGATCGCGGCTGTTGATCGCCGCGGGCGATGTGCATTTCGGCGCCGTGGCGTCGGCAAG
GGATTAGAAGAGGAGAGGGC

Downstream 100 bases:

>100_bases
GGAGGGAGATGCTCAAGCGGCTCAATCACGTTGCGATCGCTGTGCCCGATCTTGAGGCAGCCGCCGCCACCTATCGTGAC
GTGTTGGGCGCCACCGTCTC

Product: beta-lactamase-like

Products: NA

Alternate protein names: RNase J [H]

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MASDEAELVFCPLGGVGEIGMNLALYGYGPRDNRTWIMIDCGVSFPGENLPGVDLILPDVSFIEDQLENLAGIIITHAHE
DHYGALLDLWPRLKTNVWMTPFTAGLLEAKRQGEVNAPKVPVTIYKAGETFTVGPFAIEAIAVAHSIPEPVSLAITTPAG
TVIHTGDWKIDPAPELGPKTDEARFRALGEKGVLALICDSTNAMREGVSPSEQDVGRGLREVIEKAPGRVAVTTFSSNVG
RIRSIAEAARDAGRQVLVLGRSLQRVIDVADELGYLDGLPPFLVEEDFGYIPRENAVILCTGSQGEARAALAKLARDEMR
NVALSPGDTVIFSSRTIPGNEKAILTIKNQLIEQGIRVVEDSDALVHVSGHPRRNELKQMYEWVRPRILVPVHGEAAHLV
AQGSLGAMSGIPEVAQVRNGGMLRLAPGPAEIIDQVPFGRIYRDGKVIGTDDEVGVRDRRKLSFAGHVAVNVVLDDRYDL
AGDPDLVAIGLPQADSAGEPMEDIMLDAAVGAVRSIPRGNRRDLDLVGEAVRRAVRAAASDAWGKKPIVTVFVTQ

Sequences:

>Translated_555_residues
MASDEAELVFCPLGGVGEIGMNLALYGYGPRDNRTWIMIDCGVSFPGENLPGVDLILPDVSFIEDQLENLAGIIITHAHE
DHYGALLDLWPRLKTNVWMTPFTAGLLEAKRQGEVNAPKVPVTIYKAGETFTVGPFAIEAIAVAHSIPEPVSLAITTPAG
TVIHTGDWKIDPAPELGPKTDEARFRALGEKGVLALICDSTNAMREGVSPSEQDVGRGLREVIEKAPGRVAVTTFSSNVG
RIRSIAEAARDAGRQVLVLGRSLQRVIDVADELGYLDGLPPFLVEEDFGYIPRENAVILCTGSQGEARAALAKLARDEMR
NVALSPGDTVIFSSRTIPGNEKAILTIKNQLIEQGIRVVEDSDALVHVSGHPRRNELKQMYEWVRPRILVPVHGEAAHLV
AQGSLGAMSGIPEVAQVRNGGMLRLAPGPAEIIDQVPFGRIYRDGKVIGTDDEVGVRDRRKLSFAGHVAVNVVLDDRYDL
AGDPDLVAIGLPQADSAGEPMEDIMLDAAVGAVRSIPRGNRRDLDLVGEAVRRAVRAAASDAWGKKPIVTVFVTQ
>Mature_554_residues
ASDEAELVFCPLGGVGEIGMNLALYGYGPRDNRTWIMIDCGVSFPGENLPGVDLILPDVSFIEDQLENLAGIIITHAHED
HYGALLDLWPRLKTNVWMTPFTAGLLEAKRQGEVNAPKVPVTIYKAGETFTVGPFAIEAIAVAHSIPEPVSLAITTPAGT
VIHTGDWKIDPAPELGPKTDEARFRALGEKGVLALICDSTNAMREGVSPSEQDVGRGLREVIEKAPGRVAVTTFSSNVGR
IRSIAEAARDAGRQVLVLGRSLQRVIDVADELGYLDGLPPFLVEEDFGYIPRENAVILCTGSQGEARAALAKLARDEMRN
VALSPGDTVIFSSRTIPGNEKAILTIKNQLIEQGIRVVEDSDALVHVSGHPRRNELKQMYEWVRPRILVPVHGEAAHLVA
QGSLGAMSGIPEVAQVRNGGMLRLAPGPAEIIDQVPFGRIYRDGKVIGTDDEVGVRDRRKLSFAGHVAVNVVLDDRYDLA
GDPDLVAIGLPQADSAGEPMEDIMLDAAVGAVRSIPRGNRRDLDLVGEAVRRAVRAAASDAWGKKPIVTVFVTQ

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 59689; Mature: 59558

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASDEAELVFCPLGGVGEIGMNLALYGYGPRDNRTWIMIDCGVSFPGENLPGVDLILPDV
CCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCEEEECCH
SFIEDQLENLAGIIITHAHEDHYGALLDLWPRLKTNVWMTPFTAGLLEAKRQGEVNAPKV
HHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHCCCCCCCCC
PVTIYKAGETFTVGPFAIEAIAVAHSIPEPVSLAITTPAGTVIHTGDWKIDPAPELGPKT
CEEEEECCCEEEECHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCEEECCCCCCCCCC
DEARFRALGEKGVLALICDSTNAMREGVSPSEQDVGRGLREVIEKAPGRVAVTTFSSNVG
CHHHHHHCCCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHH
RIRSIAEAARDAGRQVLVLGRSLQRVIDVADELGYLDGLPPFLVEEDFGYIPRENAVILC
HHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCCEEEEE
TGSQGEARAALAKLARDEMRNVALSPGDTVIFSSRTIPGNEKAILTIKNQLIEQGIRVVE
ECCCCHHHHHHHHHHHHHHHHEECCCCCEEEEECCCCCCCCEEEEEEHHHHHHHCCEEEE
DSDALVHVSGHPRRNELKQMYEWVRPRILVPVHGEAAHLVAQGSLGAMSGIPEVAQVRNG
CCCCEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCEEEEECCCCCCCCCCCHHHHHCCC
GMLRLAPGPAEIIDQVPFGRIYRDGKVIGTDDEVGVRDRRKLSFAGHVAVNVVLDDRYDL
CEEEECCCHHHHHHCCCCCCEEECCEEECCCCCCCCCCCCEEEEECEEEEEEEEECCCCC
AGDPDLVAIGLPQADSAGEPMEDIMLDAAVGAVRSIPRGNRRDLDLVGEAVRRAVRAAAS
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
DAWGKKPIVTVFVTQ
HCCCCCCEEEEEEEC
>Mature Secondary Structure 
ASDEAELVFCPLGGVGEIGMNLALYGYGPRDNRTWIMIDCGVSFPGENLPGVDLILPDV
CCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCEEEECCH
SFIEDQLENLAGIIITHAHEDHYGALLDLWPRLKTNVWMTPFTAGLLEAKRQGEVNAPKV
HHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHCCCCCCCCC
PVTIYKAGETFTVGPFAIEAIAVAHSIPEPVSLAITTPAGTVIHTGDWKIDPAPELGPKT
CEEEEECCCEEEECHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCEEECCCCCCCCCC
DEARFRALGEKGVLALICDSTNAMREGVSPSEQDVGRGLREVIEKAPGRVAVTTFSSNVG
CHHHHHHCCCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHH
RIRSIAEAARDAGRQVLVLGRSLQRVIDVADELGYLDGLPPFLVEEDFGYIPRENAVILC
HHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCCCEEEEE
TGSQGEARAALAKLARDEMRNVALSPGDTVIFSSRTIPGNEKAILTIKNQLIEQGIRVVE
ECCCCHHHHHHHHHHHHHHHHEECCCCCEEEEECCCCCCCCEEEEEEHHHHHHHCCEEEE
DSDALVHVSGHPRRNELKQMYEWVRPRILVPVHGEAAHLVAQGSLGAMSGIPEVAQVRNG
CCCCEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCEEEEECCCCCCCCCCCHHHHHCCC
GMLRLAPGPAEIIDQVPFGRIYRDGKVIGTDDEVGVRDRRKLSFAGHVAVNVVLDDRYDL
CEEEECCCHHHHHHCCCCCCEEECCEEECCCCCCCCCCCCEEEEECEEEEEEEEECCCCC
AGDPDLVAIGLPQADSAGEPMEDIMLDAAVGAVRSIPRGNRRDLDLVGEAVRRAVRAAAS
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
DAWGKKPIVTVFVTQ
HCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]