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The map label for this gene is birA [H]

Identifier: 110633390

GI number: 110633390

Start: 1138423

End: 1139247

Strand: Direct

Name: birA [H]

Synonym: Meso_1036

Alternate gene names: 110633390

Gene position: 1138423-1139247 (Clockwise)

Preceding gene: 110633389

Following gene: 110633391

Centisome position: 25.8

GC content: 64.97

Gene sequence:

>825_bases
ATGTTCGCGCTCGCGGCTTCGGCTTCTGCCGCAGGGTACCGGCTGGAGGCGCATGAGAGCGTCGGGTCGACAAATGTCTT
GGCGCTCGAAAGGGCTGTGAGCGGCGATCCCGGAAAGCTTTGGGTCGTCTCGAAAAACCAGACAAGTGGGCGCGGCAGGC
GGGGCCGGACCTGGGAAACGCCTGCGGGCAACCTCGCCGCCACGCTGCTTCTTGCCGACCGGATTGAACCGGGCGCTGCC
GCAACGCTCGGCTTCGTGGCCGGATTGTCACTTTCGGATGCTCTGCGTCAGGCCGCGCCGTCGGCGCGGCTCGGCATCGG
GATCGATGGCGGCGAGGGGAAGGCAGAGCGCACCCGCTTCGAGCTCAAATGGCCAAATGATGTGCTTGCGGATGGCGCCA
AGCTCGCGGGCATCCTGCTTGAATCCTCCGTGCTGGGGGAGGGCCGGTTCGCGGTGGCGATCGGCATCGGCGTCAACATC
GTCTCGCATCCCGTCGACACGCCTTACCCGGCGATCTCCCTGCAGGGGCTTGGGGCGGATTGCGATGCCGAACGTCTATT
TGAGGCGCTGTCGGCCGCGTGGGTCGAAAATTTTGCTCTTTGGCAAGGGCCGCGCGGCATGTCGGCCATCCGCGACCGCT
GGCTGGAAAACGCCGCGGGCCTCGGTTCCACAGTTTCGGTGCGTGCCGATGGAAGAGTGGTGCGCGGGATTTTCGAAACA
ATCGACGAACAATGCCGGTTCGTCGTAAGGGAGGATAATGGATCGCGGCTGTTGATCGCCGCGGGCGATGTGCATTTCGG
CGCCGTGGCGTCGGCAAGGGATTAG

Upstream 100 bases:

>100_bases
CTTGTGCTTACTCTATCGGGCGCTTTCGTGCTTCTTTACGTGTTCTTCGGCGGCCCTGTCGGCCGGCTGGCGGAAGCCGC
AGCGTCGACGTTCTTTTAAG

Downstream 100 bases:

>100_bases
AAGAGGAGAGGGCGTGGCGTCCGACGAAGCGGAACTGGTTTTTTGCCCTTTGGGTGGTGTCGGCGAGATCGGCATGAATT
TGGCCCTCTATGGTTACGGG

Product: biotin--acetyl-CoA-carboxylase ligase

Products: NA

Alternate protein names: Biotin--protein ligase [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MFALAASASAAGYRLEAHESVGSTNVLALERAVSGDPGKLWVVSKNQTSGRGRRGRTWETPAGNLAATLLLADRIEPGAA
ATLGFVAGLSLSDALRQAAPSARLGIGIDGGEGKAERTRFELKWPNDVLADGAKLAGILLESSVLGEGRFAVAIGIGVNI
VSHPVDTPYPAISLQGLGADCDAERLFEALSAAWVENFALWQGPRGMSAIRDRWLENAAGLGSTVSVRADGRVVRGIFET
IDEQCRFVVREDNGSRLLIAAGDVHFGAVASARD

Sequences:

>Translated_274_residues
MFALAASASAAGYRLEAHESVGSTNVLALERAVSGDPGKLWVVSKNQTSGRGRRGRTWETPAGNLAATLLLADRIEPGAA
ATLGFVAGLSLSDALRQAAPSARLGIGIDGGEGKAERTRFELKWPNDVLADGAKLAGILLESSVLGEGRFAVAIGIGVNI
VSHPVDTPYPAISLQGLGADCDAERLFEALSAAWVENFALWQGPRGMSAIRDRWLENAAGLGSTVSVRADGRVVRGIFET
IDEQCRFVVREDNGSRLLIAAGDVHFGAVASARD
>Mature_274_residues
MFALAASASAAGYRLEAHESVGSTNVLALERAVSGDPGKLWVVSKNQTSGRGRRGRTWETPAGNLAATLLLADRIEPGAA
ATLGFVAGLSLSDALRQAAPSARLGIGIDGGEGKAERTRFELKWPNDVLADGAKLAGILLESSVLGEGRFAVAIGIGVNI
VSHPVDTPYPAISLQGLGADCDAERLFEALSAAWVENFALWQGPRGMSAIRDRWLENAAGLGSTVSVRADGRVVRGIFET
IDEQCRFVVREDNGSRLLIAAGDVHFGAVASARD

Specific function: Activates biotin to form biotinyl-5'-adenylate and transfers the biotin moiety to biotin-accepting proteins [H]

COG id: COG0340

COG function: function code H; Biotin-(acetyl-CoA carboxylase) ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the biotin--protein ligase family [H]

Homologues:

Organism=Escherichia coli, GI1790408, Length=243, Percent_Identity=29.6296296296296, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004408
- InterPro:   IPR003142
- InterPro:   IPR004143 [H]

Pfam domain/function: PF02237 BPL_C; PF03099 BPL_LipA_LipB [H]

EC number: =6.3.4.15 [H]

Molecular weight: Translated: 28662; Mature: 28662

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFALAASASAAGYRLEAHESVGSTNVLALERAVSGDPGKLWVVSKNQTSGRGRRGRTWET
CEEEECCCCCCCEEEEEHHCCCCCCEEEEEHHHCCCCCEEEEEECCCCCCCCCCCCCCCC
PAGNLAATLLLADRIEPGAAATLGFVAGLSLSDALRQAAPSARLGIGIDGGEGKAERTRF
CCCCHHEEEHHHHCCCCCHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEECCCCCCCCEEE
ELKWPNDVLADGAKLAGILLESSVLGEGRFAVAIGIGVNIVSHPVDTPYPAISLQGLGAD
EEECCCHHHHCCHHHHHHHHHHHHCCCCCEEEEEEECCEEEECCCCCCCCEEEEECCCCC
CDAERLFEALSAAWVENFALWQGPRGMSAIRDRWLENAAGLGSTVSVRADGRVVRGIFET
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHH
IDEQCRFVVREDNGSRLLIAAGDVHFGAVASARD
HHHHCEEEEEECCCCEEEEEECCEEECCCCCCCC
>Mature Secondary Structure
MFALAASASAAGYRLEAHESVGSTNVLALERAVSGDPGKLWVVSKNQTSGRGRRGRTWET
CEEEECCCCCCCEEEEEHHCCCCCCEEEEEHHHCCCCCEEEEEECCCCCCCCCCCCCCCC
PAGNLAATLLLADRIEPGAAATLGFVAGLSLSDALRQAAPSARLGIGIDGGEGKAERTRF
CCCCHHEEEHHHHCCCCCHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEECCCCCCCCEEE
ELKWPNDVLADGAKLAGILLESSVLGEGRFAVAIGIGVNIVSHPVDTPYPAISLQGLGAD
EEECCCHHHHCCHHHHHHHHHHHHCCCCCEEEEEEECCEEEECCCCCCCCEEEEECCCCC
CDAERLFEALSAAWVENFALWQGPRGMSAIRDRWLENAAGLGSTVSVRADGRVVRGIFET
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHH
IDEQCRFVVREDNGSRLLIAAGDVHFGAVASARD
HHHHCEEEEEECCCCEEEEEECCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8422400 [H]