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The map label for this gene is appC [H]

Identifier: 110633351

GI number: 110633351

Start: 1094320

End: 1095201

Strand: Reverse

Name: appC [H]

Synonym: Meso_0997

Alternate gene names: 110633351

Gene position: 1095201-1094320 (Counterclockwise)

Preceding gene: 110633352

Following gene: 110633350

Centisome position: 24.82

GC content: 62.7

Gene sequence:

>882_bases
ATGTCCTCGGCAGATCTGACCCAAACGCAACAGACGCCACGCCCGGCTTTCGGCATTCTGGCCCGCATTCGCCGTCAGGT
GCCGGCTTCCGTAGGGTTTGGCATCTTGTGGCTCGCTGCCATGGTGCTGATTGCGATCCTGGCCGATTGGCTGCGTCCCT
ACGGCATCACCGCCATGGATCTGACCAGCCGCCTCTCCCCGCCGGGAACCCCCGGCCATTGGCTGGGTACCGACGAGCTT
GGCCGGGACGTGCTCTCCCGCCTCATCCAGTCAATCCGCGTTTCGCTGGTCATCGCCTTCGGCGCGACCATCATCTCCGC
CGTCTTTGGAACTACGCTCGGCTTTCTGGCCGCCCAGTTCCGCGGCACGGTCGAGCATCTGGTGCTCGTGCTTGCAGACT
TTCAAGCCGCCTTGCCCTTTCTCATCATGTCGCTGGCAGTTCTGGCCTTCTTTGGCTCCTCCATGATGCTCCTGGTCTGC
CTCATGGGCTTCTACGGCTGGGAGAGATATGCGCGCATAGCGCGCGGGCTTGCGATTTCGGCCGGGGCGCAGGGCTATGC
CGCGTCTGTGGTCCAGCTTGGGGCCAACCCCGCCCGCGTCTATTTCCGGCACATATTGCCCAACGTCGCCTCGACGCTGA
TCGTCTCGATGACACTCACCTTTCCCGAGATCATTCTCATGGAAAGCGGGCTCTCCTTCCTCGGCCTCGGCGTGCAGCCG
CCGGAATCGAGCCTCGGCAACATGGTCGGGTTCGGGCGTGAATATCTCACCAGCGCACCATGGATCATGCTCGCGCCTGC
GGCCGTGATCATGGTGACAACGCTTTCCATATCGCTTGTCGGGGACTGGCTTCGCGACAAGCTCGACCCAACCATCCGCT
AA

Upstream 100 bases:

>100_bases
GCCGCCATGGTGATTTCCAACCTGGTTGTGGACCTCCTCTACGGCTGGCTCGACCCGCGACTGCGCGCGCATGTCGCGCA
TTAGGTAACAGGAAGAAGGC

Downstream 100 bases:

>100_bases
GAGGTAGCCATGACACTGATCACCGGCCATCGCGGAGCCCGCAACCTCTGGCCTGAAAATTCCCTGACCGGATTTCGTAA
CGTGCTTCAGCTTGGCGTCG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSSADLTQTQQTPRPAFGILARIRRQVPASVGFGILWLAAMVLIAILADWLRPYGITAMDLTSRLSPPGTPGHWLGTDEL
GRDVLSRLIQSIRVSLVIAFGATIISAVFGTTLGFLAAQFRGTVEHLVLVLADFQAALPFLIMSLAVLAFFGSSMMLLVC
LMGFYGWERYARIARGLAISAGAQGYAASVVQLGANPARVYFRHILPNVASTLIVSMTLTFPEIILMESGLSFLGLGVQP
PESSLGNMVGFGREYLTSAPWIMLAPAAVIMVTTLSISLVGDWLRDKLDPTIR

Sequences:

>Translated_293_residues
MSSADLTQTQQTPRPAFGILARIRRQVPASVGFGILWLAAMVLIAILADWLRPYGITAMDLTSRLSPPGTPGHWLGTDEL
GRDVLSRLIQSIRVSLVIAFGATIISAVFGTTLGFLAAQFRGTVEHLVLVLADFQAALPFLIMSLAVLAFFGSSMMLLVC
LMGFYGWERYARIARGLAISAGAQGYAASVVQLGANPARVYFRHILPNVASTLIVSMTLTFPEIILMESGLSFLGLGVQP
PESSLGNMVGFGREYLTSAPWIMLAPAAVIMVTTLSISLVGDWLRDKLDPTIR
>Mature_292_residues
SSADLTQTQQTPRPAFGILARIRRQVPASVGFGILWLAAMVLIAILADWLRPYGITAMDLTSRLSPPGTPGHWLGTDELG
RDVLSRLIQSIRVSLVIAFGATIISAVFGTTLGFLAAQFRGTVEHLVLVLADFQAALPFLIMSLAVLAFFGSSMMLLVCL
MGFYGWERYARIARGLAISAGAQGYAASVVQLGANPARVYFRHILPNVASTLIVSMTLTFPEIILMESGLSFLGLGVQPP
ESSLGNMVGFGREYLTSAPWIMLAPAAVIMVTTLSISLVGDWLRDKLDPTIR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=293, Percent_Identity=32.4232081911263, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1787760, Length=251, Percent_Identity=33.4661354581673, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789889, Length=245, Percent_Identity=33.8775510204082, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1789964, Length=257, Percent_Identity=35.0194552529183, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787498, Length=260, Percent_Identity=35, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1787549, Length=262, Percent_Identity=30.1526717557252, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1788505, Length=245, Percent_Identity=25.7142857142857, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31543; Mature: 31412

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSADLTQTQQTPRPAFGILARIRRQVPASVGFGILWLAAMVLIAILADWLRPYGITAMD
CCCCCCCCCCCCCCHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LTSRLSPPGTPGHWLGTDELGRDVLSRLIQSIRVSLVIAFGATIISAVFGTTLGFLAAQF
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGTVEHLVLVLADFQAALPFLIMSLAVLAFFGSSMMLLVCLMGFYGWERYARIARGLAIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHC
AGAQGYAASVVQLGANPARVYFRHILPNVASTLIVSMTLTFPEIILMESGLSFLGLGVQP
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
PESSLGNMVGFGREYLTSAPWIMLAPAAVIMVTTLSISLVGDWLRDKLDPTIR
CHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SSADLTQTQQTPRPAFGILARIRRQVPASVGFGILWLAAMVLIAILADWLRPYGITAMD
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LTSRLSPPGTPGHWLGTDELGRDVLSRLIQSIRVSLVIAFGATIISAVFGTTLGFLAAQF
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGTVEHLVLVLADFQAALPFLIMSLAVLAFFGSSMMLLVCLMGFYGWERYARIARGLAIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHC
AGAQGYAASVVQLGANPARVYFRHILPNVASTLIVSMTLTFPEIILMESGLSFLGLGVQP
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
PESSLGNMVGFGREYLTSAPWIMLAPAAVIMVTTLSISLVGDWLRDKLDPTIR
CHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]