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The map label for this gene is sugE [H]

Identifier: 110633336

GI number: 110633336

Start: 1077887

End: 1078204

Strand: Direct

Name: sugE [H]

Synonym: Meso_0982

Alternate gene names: 110633336

Gene position: 1077887-1078204 (Clockwise)

Preceding gene: 110633333

Following gene: 110633343

Centisome position: 24.43

GC content: 62.26

Gene sequence:

>318_bases
ATGGCCTGGTTTGCACTGTTTGCCGCTGGCCTCTTTGAAGTGGGATGGGCGGTCGGACTGAAATACACGGACGGCTTCAC
CCGGCTTTGGCCGACGGTCTGGACCATCCTCTCCATGATCGTCAGCCTTGGCCTTCTCGGGATCGCGCTTCGCACCCTCC
CGCTTGGGACGGCCTATGCGATCTGGACCGGCGTTGGCACGATCGGCACCGTCATTCTCGGCATTATGCTTTTCGGCGAG
TCGGCCGAGGCCATCCGGCTCGCCTGCATCGGCCTGATCGTGGCCGGCATTATCGGCCTGAAGCTCGTCACACCTTGA

Upstream 100 bases:

>100_bases
TTGCGGCCACCGGCCGGTACCTTTATATCGGCGGTGCAGGGACGGCCTTGCTTTCTTCTATCCGGATGAGGACGGCCTCA
TCGCTATTGTGGAGATCAGC

Downstream 100 bases:

>100_bases
ATGTCACTATTGCCCGCCCGCCGCGAGCAGCGACAGCTGGCGTACATTGTCGGTACCATGGTGGTCGGTAAGCTGGGTCG
GATATTCGGCGGTGAAGCAG

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 105; Mature: 104

Protein sequence:

>105_residues
MAWFALFAAGLFEVGWAVGLKYTDGFTRLWPTVWTILSMIVSLGLLGIALRTLPLGTAYAIWTGVGTIGTVILGIMLFGE
SAEAIRLACIGLIVAGIIGLKLVTP

Sequences:

>Translated_105_residues
MAWFALFAAGLFEVGWAVGLKYTDGFTRLWPTVWTILSMIVSLGLLGIALRTLPLGTAYAIWTGVGTIGTVILGIMLFGE
SAEAIRLACIGLIVAGIIGLKLVTP
>Mature_104_residues
AWFALFAAGLFEVGWAVGLKYTDGFTRLWPTVWTILSMIVSLGLLGIALRTLPLGTAYAIWTGVGTIGTVILGIMLFGES
AEAIRLACIGLIVAGIIGLKLVTP

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=104, Percent_Identity=61.5384615384615, Blast_Score=123, Evalue=3e-30,
Organism=Escherichia coli, GI1786755, Length=85, Percent_Identity=38.8235294117647, Blast_Score=59, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11083; Mature: 10951

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWFALFAAGLFEVGWAVGLKYTDGFTRLWPTVWTILSMIVSLGLLGIALRTLPLGTAYA
CHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
IWTGVGTIGTVILGIMLFGESAEAIRLACIGLIVAGIIGLKLVTP
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AWFALFAAGLFEVGWAVGLKYTDGFTRLWPTVWTILSMIVSLGLLGIALRTLPLGTAYA
HHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
IWTGVGTIGTVILGIMLFGESAEAIRLACIGLIVAGIIGLKLVTP
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA