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The map label for this gene is pleC [H]

Identifier: 110633259

GI number: 110633259

Start: 998227

End: 1000551

Strand: Reverse

Name: pleC [H]

Synonym: Meso_0905

Alternate gene names: 110633259

Gene position: 1000551-998227 (Counterclockwise)

Preceding gene: 110633260

Following gene: 110633241

Centisome position: 22.68

GC content: 63.23

Gene sequence:

>2325_bases
ATGGCGAGCGCGTATGCGTGGGCATTGCCTACCGCCCTGTTCTCCAGGGGCGGAAGGCCTAAGGCGGAAACCGAGGTCGC
CGGCAATGCGAAGATCATTGCCGCGCCGGCTTATGAGCGCCTGCTCGCAATCGAGCCCTACCTGCGTCGGGCCATTCCGA
TCCTGATCGTCATTTTCCTGCTGATCCTCGCGGCGGCGCGCCTGGTGACACTGCTCAACTGGCACGGCGACATCGAGAAG
GATACCAAACGGCATCTCGGCATGGTCGCCAGCAACCTTGCCCAGGCGGTGCAGATTGCGGGTGTGGAGTCGCTCGCTGA
GGTGGGTCAAGCCGAAGTGCTGATCGACGAGACGATCCTGCGTGCCAGCATGGATGCCGGCTGGGTGCTCGCGCTCACCG
ATTCCCGGTTCGCTGTCACTGCCGTTTCCGCGAGCGCGCAGAAGATGAAGGGGCAATCCCTCGAAACCGTCGTTTCGGGC
GGGCAGCCGCTCTTCATGTTTGGCGACAGAGCCGGCGTGCTGGAGGTGCAGATCGGCGAGGCGACATGGTATGCCGCGGT
GAGCCTGCTTCCCGGTGGTGACGGCGCCGCCGTCGCACTTGCGCCCCAGGACCAGGTGTTCGGCGCGTGGCGCAGCACCG
TCTCGCTCAATGTGACGCTCTTTGCCCTGACCGCCGGGGTGCTGATGGCGATCCTTTACGCCTATTTCAGCCAGGCCGCA
CGCGCGCAGGCAGCCGACCGCATTTACCGCGAAGCACATCAAAGGGTGGACCTCGCCCTTGTGCGCGGGAAGTGCGGCCT
TTGGGACTGGGACATGGCGCGCGGCAAGATGTACTGGTCCGCCTCCATGTACGAGATGCTGGGCTACGAGGCCGCCGATG
TGATGCTTTCCTTCGGCGATGTGGCGAGCTTGCTTCATCCCGATGACAGCGATCTGTTCGCCGTCGCGAACAGGATCGTC
GCACGCGAGGTCGAGCAGGTCGACCAGGTGTTCCGGATGCGCCATGCCAACGGCCAATGGATCTGGATCCGGGCCAGAGC
GCAGGTGGTGGACCCGGATGCGCCGGAGATTCACCTGATCGGCATTGCGGTGGACGTGACGGAACAACGCACGCTGGTGC
AGCAGTCGGAGGCCGCGGACCAAAGGCTGCGCACGGCGATCGAGAACATCACGGAATCCTTCGTGCTTTGGGACGCGTCC
GAGCGGCTCGTGATGTGCAATTCACGTTATCTGCAGGACACGGGCCTTGATCCAAGCGAGATCGTTCCGGGCCTGCCCCG
CCAGGAAATCGAATCCCGCATGAAGGCCACGCGCTATGAGCGGCGGCTGACGGGATCGAACAACGCCAGCGAGGGCATCA
CCTATGAACGGCAGCTGGCGGACGGCCGCTGGCTGCAGGTGACGGAGCTGAAGACGCGTGACGGCGGCACGGTTTCCGTG
GGAACCGACATTACCCAGCTCAAGCAGCACCAGGAAAAGCTGGTGGAGAGCGAACGCCGGCTGATGGCGACGATCCATGA
TCTGTCCCTCGCGCGCCGCGCGGAGCAGGAGCGCGGCCAGGAGCTCGTGGAGCTCAACCGCAAATATATGCGCGAGACCG
AGCGCGCCGAATCCGCCAACCGCGCGAAATCGGAATTCCTCGCGAATATGTCCCACGAGTTGCGGACACCGCTCAACGCC
ATCATCGGCTTCTCGGAACTGATGCAGCAGGGACTGTTCGGTCCGCTCGGCTCGGAGCGCTATCAGGAATATGTGAACGA
CATCTACTCCAGCGGCACATATCTGCTCGGCGTGATCAATGACATCCTCGACATGTCGAAGATCGAGGCAGGCCAGTTCT
CAATCCACCGGGAGAGCATCGACCTTTCCGAGGTCATCCGCGAAACCATGCGCGTGGTGACGCTGCAGGCGGGAAAGAAG
AACATAGAACTGACAAGCGACGTTCCAGCCTCTCTCTCGCTTCACGCGGACCGTCGCGCGGTGAAGCAGATCCTCATCAA
TCTCCTCTTCAACGCCGTCAAATTCACCGGCCAAGGTGGACGCGTGACGCTTCGGGCCCGCGTGGTTTCGAACTCACTGA
TGCTGACGATCAAGGACACCGGCTGCGGCATTCCACGCGAGGCATTGAAGAAGCTCGGCCGGCCATTCGAGCAGGTGGAG
AACCAGTATTCGCGCAGTCACAACGGCTCCGGCCTCGGCCTGGCGATTTCGCGTTCGCTCACCGAGCTTCATGGCGGCGC
GCTGCGCATCCGCTCCACCGAAGGCGTGGGCACGATCGTCTCCATCCGGCTACCCGTGCAGATGGCGCGCAGGATGGCGG
CGTAG

Upstream 100 bases:

>100_bases
TAGACAAGGCGAATCAGCTTTGATTCTTTATGGATGATTCGCATGTACGCGTTCGCGGATCGGTCAAGCAGAATCCAGCA
GGAAGAAAGGGCCCGTCGGG

Downstream 100 bases:

>100_bases
CGGCATTCAAACTGCCCGATATGTTTGCGCTCCCCTTCGCGCCCCTCGTGTGGGAGATGGCCGGCAGAGGCCAGAGGGGG
GCGCGACCGGCACAAACCTG

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 774; Mature: 773

Protein sequence:

>774_residues
MASAYAWALPTALFSRGGRPKAETEVAGNAKIIAAPAYERLLAIEPYLRRAIPILIVIFLLILAAARLVTLLNWHGDIEK
DTKRHLGMVASNLAQAVQIAGVESLAEVGQAEVLIDETILRASMDAGWVLALTDSRFAVTAVSASAQKMKGQSLETVVSG
GQPLFMFGDRAGVLEVQIGEATWYAAVSLLPGGDGAAVALAPQDQVFGAWRSTVSLNVTLFALTAGVLMAILYAYFSQAA
RAQAADRIYREAHQRVDLALVRGKCGLWDWDMARGKMYWSASMYEMLGYEAADVMLSFGDVASLLHPDDSDLFAVANRIV
AREVEQVDQVFRMRHANGQWIWIRARAQVVDPDAPEIHLIGIAVDVTEQRTLVQQSEAADQRLRTAIENITESFVLWDAS
ERLVMCNSRYLQDTGLDPSEIVPGLPRQEIESRMKATRYERRLTGSNNASEGITYERQLADGRWLQVTELKTRDGGTVSV
GTDITQLKQHQEKLVESERRLMATIHDLSLARRAEQERGQELVELNRKYMRETERAESANRAKSEFLANMSHELRTPLNA
IIGFSELMQQGLFGPLGSERYQEYVNDIYSSGTYLLGVINDILDMSKIEAGQFSIHRESIDLSEVIRETMRVVTLQAGKK
NIELTSDVPASLSLHADRRAVKQILINLLFNAVKFTGQGGRVTLRARVVSNSLMLTIKDTGCGIPREALKKLGRPFEQVE
NQYSRSHNGSGLGLAISRSLTELHGGALRIRSTEGVGTIVSIRLPVQMARRMAA

Sequences:

>Translated_774_residues
MASAYAWALPTALFSRGGRPKAETEVAGNAKIIAAPAYERLLAIEPYLRRAIPILIVIFLLILAAARLVTLLNWHGDIEK
DTKRHLGMVASNLAQAVQIAGVESLAEVGQAEVLIDETILRASMDAGWVLALTDSRFAVTAVSASAQKMKGQSLETVVSG
GQPLFMFGDRAGVLEVQIGEATWYAAVSLLPGGDGAAVALAPQDQVFGAWRSTVSLNVTLFALTAGVLMAILYAYFSQAA
RAQAADRIYREAHQRVDLALVRGKCGLWDWDMARGKMYWSASMYEMLGYEAADVMLSFGDVASLLHPDDSDLFAVANRIV
AREVEQVDQVFRMRHANGQWIWIRARAQVVDPDAPEIHLIGIAVDVTEQRTLVQQSEAADQRLRTAIENITESFVLWDAS
ERLVMCNSRYLQDTGLDPSEIVPGLPRQEIESRMKATRYERRLTGSNNASEGITYERQLADGRWLQVTELKTRDGGTVSV
GTDITQLKQHQEKLVESERRLMATIHDLSLARRAEQERGQELVELNRKYMRETERAESANRAKSEFLANMSHELRTPLNA
IIGFSELMQQGLFGPLGSERYQEYVNDIYSSGTYLLGVINDILDMSKIEAGQFSIHRESIDLSEVIRETMRVVTLQAGKK
NIELTSDVPASLSLHADRRAVKQILINLLFNAVKFTGQGGRVTLRARVVSNSLMLTIKDTGCGIPREALKKLGRPFEQVE
NQYSRSHNGSGLGLAISRSLTELHGGALRIRSTEGVGTIVSIRLPVQMARRMAA
>Mature_773_residues
ASAYAWALPTALFSRGGRPKAETEVAGNAKIIAAPAYERLLAIEPYLRRAIPILIVIFLLILAAARLVTLLNWHGDIEKD
TKRHLGMVASNLAQAVQIAGVESLAEVGQAEVLIDETILRASMDAGWVLALTDSRFAVTAVSASAQKMKGQSLETVVSGG
QPLFMFGDRAGVLEVQIGEATWYAAVSLLPGGDGAAVALAPQDQVFGAWRSTVSLNVTLFALTAGVLMAILYAYFSQAAR
AQAADRIYREAHQRVDLALVRGKCGLWDWDMARGKMYWSASMYEMLGYEAADVMLSFGDVASLLHPDDSDLFAVANRIVA
REVEQVDQVFRMRHANGQWIWIRARAQVVDPDAPEIHLIGIAVDVTEQRTLVQQSEAADQRLRTAIENITESFVLWDASE
RLVMCNSRYLQDTGLDPSEIVPGLPRQEIESRMKATRYERRLTGSNNASEGITYERQLADGRWLQVTELKTRDGGTVSVG
TDITQLKQHQEKLVESERRLMATIHDLSLARRAEQERGQELVELNRKYMRETERAESANRAKSEFLANMSHELRTPLNAI
IGFSELMQQGLFGPLGSERYQEYVNDIYSSGTYLLGVINDILDMSKIEAGQFSIHRESIDLSEVIRETMRVVTLQAGKKN
IELTSDVPASLSLHADRRAVKQILINLLFNAVKFTGQGGRVTLRARVVSNSLMLTIKDTGCGIPREALKKLGRPFEQVEN
QYSRSHNGSGLGLAISRSLTELHGGALRIRSTEGVGTIVSIRLPVQMARRMAA

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=233, Percent_Identity=38.1974248927039, Blast_Score=147, Evalue=4e-36,
Organism=Escherichia coli, GI1788713, Length=249, Percent_Identity=34.9397590361446, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI87081816, Length=258, Percent_Identity=36.4341085271318, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI145693157, Length=236, Percent_Identity=37.7118644067797, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI48994928, Length=252, Percent_Identity=33.3333333333333, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1786600, Length=224, Percent_Identity=31.25, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788549, Length=224, Percent_Identity=29.4642857142857, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1788393, Length=279, Percent_Identity=25.8064516129032, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=30.2631578947368, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790436, Length=252, Percent_Identity=25.3968253968254, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI87082128, Length=245, Percent_Identity=28.1632653061224, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790861, Length=250, Percent_Identity=27.2, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786783, Length=249, Percent_Identity=26.1044176706827, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788279, Length=229, Percent_Identity=24.8908296943231, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1790346, Length=227, Percent_Identity=25.1101321585903, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1789808, Length=231, Percent_Identity=27.7056277056277, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790300, Length=254, Percent_Identity=24.0157480314961, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 85494; Mature: 85363

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASAYAWALPTALFSRGGRPKAETEVAGNAKIIAAPAYERLLAIEPYLRRAIPILIVIFL
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
LILAAARLVTLLNWHGDIEKDTKRHLGMVASNLAQAVQIAGVESLAEVGQAEVLIDETIL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHH
RASMDAGWVLALTDSRFAVTAVSASAQKMKGQSLETVVSGGQPLFMFGDRAGVLEVQIGE
HHCCCCCEEEEEECCCEEEEEEHHHHHHHCCCHHHHHHCCCCEEEEECCCCCEEEEEECC
ATWYAAVSLLPGGDGAAVALAPQDQVFGAWRSTVSLNVTLFALTAGVLMAILYAYFSQAA
EEEEEEEEEEECCCCCEEEECCCHHHHHHHHCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
RAQAADRIYREAHQRVDLALVRGKCGLWDWDMARGKMYWSASMYEMLGYEAADVMLSFGD
HHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHCCEEEEHHHHHHHHCCHHHHHHHHHHH
VASLLHPDDSDLFAVANRIVAREVEQVDQVFRMRHANGQWIWIRARAQVVDPDAPEIHLI
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCEEEE
GIAVDVTEQRTLVQQSEAADQRLRTAIENITESFVLWDASERLVMCNSRYLQDTGLDPSE
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCCHHCCCCCHHH
IVPGLPRQEIESRMKATRYERRLTGSNNASEGITYERQLADGRWLQVTELKTRDGGTVSV
HCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHCCCCEEEEEEEECCCCCEEEE
GTDITQLKQHQEKLVESERRLMATIHDLSLARRAEQERGQELVELNRKYMRETERAESAN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAKSEFLANMSHELRTPLNAIIGFSELMQQGLFGPLGSERYQEYVNDIYSSGTYLLGVIN
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
DILDMSKIEAGQFSIHRESIDLSEVIRETMRVVTLQAGKKNIELTSDVPASLSLHADRRA
HHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCEEEHHHHHH
VKQILINLLFNAVKFTGQGGRVTLRARVVSNSLMLTIKDTGCGIPREALKKLGRPFEQVE
HHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCEEEEEECCCCCCCHHHHHHHCCCHHHHH
NQYSRSHNGSGLGLAISRSLTELHGGALRIRSTEGVGTIVSIRLPVQMARRMAA
HHHHHCCCCCCEEEHHHHHHHHHCCCEEEEEECCCCCEEEEEECCHHHHHHHCC
>Mature Secondary Structure 
ASAYAWALPTALFSRGGRPKAETEVAGNAKIIAAPAYERLLAIEPYLRRAIPILIVIFL
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
LILAAARLVTLLNWHGDIEKDTKRHLGMVASNLAQAVQIAGVESLAEVGQAEVLIDETIL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHH
RASMDAGWVLALTDSRFAVTAVSASAQKMKGQSLETVVSGGQPLFMFGDRAGVLEVQIGE
HHCCCCCEEEEEECCCEEEEEEHHHHHHHCCCHHHHHHCCCCEEEEECCCCCEEEEEECC
ATWYAAVSLLPGGDGAAVALAPQDQVFGAWRSTVSLNVTLFALTAGVLMAILYAYFSQAA
EEEEEEEEEEECCCCCEEEECCCHHHHHHHHCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
RAQAADRIYREAHQRVDLALVRGKCGLWDWDMARGKMYWSASMYEMLGYEAADVMLSFGD
HHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHCCEEEEHHHHHHHHCCHHHHHHHHHHH
VASLLHPDDSDLFAVANRIVAREVEQVDQVFRMRHANGQWIWIRARAQVVDPDAPEIHLI
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCEEEE
GIAVDVTEQRTLVQQSEAADQRLRTAIENITESFVLWDASERLVMCNSRYLQDTGLDPSE
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCCHHCCCCCHHH
IVPGLPRQEIESRMKATRYERRLTGSNNASEGITYERQLADGRWLQVTELKTRDGGTVSV
HCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHCCCCEEEEEEEECCCCCEEEE
GTDITQLKQHQEKLVESERRLMATIHDLSLARRAEQERGQELVELNRKYMRETERAESAN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAKSEFLANMSHELRTPLNAIIGFSELMQQGLFGPLGSERYQEYVNDIYSSGTYLLGVIN
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
DILDMSKIEAGQFSIHRESIDLSEVIRETMRVVTLQAGKKNIELTSDVPASLSLHADRRA
HHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCEEEHHHHHH
VKQILINLLFNAVKFTGQGGRVTLRARVVSNSLMLTIKDTGCGIPREALKKLGRPFEQVE
HHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCEEEEEECCCCCCCHHHHHHHCCCHHHHH
NQYSRSHNGSGLGLAISRSLTELHGGALRIRSTEGVGTIVSIRLPVQMARRMAA
HHHHHCCCCCCEEEHHHHHHHHHCCCEEEEEECCCCCEEEEEECCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]